MICROCHIMICA ACTA
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2021
·Vol. 189
·期 1
·1-7
·
IF 5.833
Xia Chunqiu,Huang Wenying,Kang Xiutang,Chen Pingyun,You Longjie,Guo Liangqia
Mo 5 N 6 nanosheets were synthesized by a nickel-induced growth method and were found to possess peroxidase-like activity in acidic condition and catalase-like activity in weak basic condition. In acidic condition, Mo 5 N 6 nanosheets can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H 2 O 2 to form a blue color product (TMB OX ). At the co-existence of 4-aminophenol (4-AP), 4-AP can react with H 2 O 2 and TMB OX , resulting in the decrease of TMB OX and the fading of blue color. Therefore, a facile, sensitive colorimetric method for the quantitative detection of 4-AP was developed. The linear range for 4-AP was 1.0 to 80.0 μmol⋅L ‒1 ( R 2 = 0.999), and the detection limit was 0.56 μmol⋅L ‒1 based on 3 σ / k . Resorcinol, aniline, humic acid, and common ions and anions in surface water did not interfere the determination of 4-AP. This colorimetric method was applied to measure the 4-AP in real water sample from Wulong River in Fujian Province of China. The relative standard deviation for the determination of 4-AP was ranged from 0.03 to 1.88%, and the recoveries from spiked samples were ranged between 99.2 and 107.6%. The determination results were consistent with those obtained by HPLC. Graphical abstract
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2021
·
IF 4.539
Qixia Guan,Hao Guo,Ning Wu,Yujuan Cao,Mingyue Wang,Longwen Zhang,Wu Yang
As a new kind of porous organic material, covalent organic framework materials (COFs) have many advantages and have been widely used in catalysis, sensing, drug delivery, gas separation and other fields. In this paper, A COF was successfully prepared based on Schiff base reaction of 1, 3, 6, 8-tetrakis(4-formyl phenyl) pyrene (TFPPy) and 1, 3, 6, 8-tetrakis(4-amino phenyl) pyrene (PyTTA) named as TF-Py COF, and its structure was characterized in detail. By physically combining a pre-prepared three-dimensional carbon material containing nitrogen (3D NCNF-T) and TF-Py COF, followed by deposition of AuNPs, relatively poor conductivity of TF-Py COF was efficiently overcome and a novel electrochemical sensing platform with high sensitivity and high selectivity for simultaneous detection of acetaminophen (ACOP) and 4-aminophenol (4-AP) was successfully constructed. The synergistic effect between TF-Py COF, 3D NCNF-T and AuNPs effectively improves the analytical sensitivity of target analytes. Under optimized experimental conditions, the electrochemical sensing platform has a sensitive volt-ampere response and a wide linear range to both ACOP and 4-AP, and the detection limits are 0.13 μM and 0.05 μM (S/N = 3), respectively. The sensor has been successfully applied to the determination of ACOP and 4-AP in acetaminophen tablets and Yellow River water samples, with high recovery rate, good selectivity and reproducibility, and strong anti-interference ability. It is expected to be widely used in the actual sample detection.
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JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
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2021
·
IF 6.064
Yafei Li,Xiaocheng Lan,Boyang Liu,Tiefeng Wang
A stable and highly efficient supported Cu-Ni catalysts for the conversion of ethyl levulinate (EL) to γ-valerolactone (GVL) was developed. The catalysts were characterized by XRD, TEM, TPD, TPR, and XPS. The support effect of metal oxides (Al 2 O 3 , SiO 2 , ZrO 2 , and TiO 2 ) revealed that Cu-Ni supported on Al 2 O 3 showed the highest activity for EL hydrogenation to ethyl 4-hydroxypentanoate (EHP) and the subsequent intramolecular esterification of EHP to GVL. EHP intramolecular esterification to GVL in the ethanol solution was a reversible reaction with an equilibrium constant of 24 at 453 K. A simplified reaction kinetic network was established. The solvent had a significant influence on the reaction equilibrium and the catalyst stability. Cu-Ni/Al 2 O 3 in n-hexane solvent gave a higher GVL yield than that in ethanol solvent, and showed better recyclability than that in toluene solvent. With optimizing the conditions, Cu-Ni/Al 2 O 3 gave 99.9% conversion and 98% selectivity to GVL with a space–time yield of 1.13 g GVL g cat -1 h −1 in n-hexane solvent with good recyclability.
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MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Yuanyuan Niu,Jianfeng Zhou,Haohong Lai,Qing Zhou,Shumei Wang,Haiyun Zhai
A sensitive and selective electrochemical sensor for sensing 4-nitroquinoline N-oxide (4-NQO) by differential pulse voltammetry was designed. Poly L-histidine (P-L-his) composite and metal-organic framework UiO-66 (Zr) modified electrode was used as the working electrode which had large specific surface area, mesoporous structure and excellent conductivity. Unlike most modification methods, UiO-66 was electrodeposited in this study. Compared with drop coating, electrodeposition proceeds efficiently under mild conditions and often requires shorter time. FTIR, EDX, TEM, SEM and electrochemical assay were used to characterize the prepared materials and modified electrodes. After that, some experimental conditions like electro-polymerization time, deposition time, pH and scan rate were also improved and optimized separately. At the UiO-66/P-L-his-modified glassy carbon electrode, a good linear relationship between 4-NQO concentration and its peak current was obtained under the best conditions in a wide range from 0.2 to 50.0 μM, and the limit of detection (S/N = 3) was 66.7 nM. Moreover, multiple experiments elucidated that the as-synthesized sensor could be applied to detect 4-NQO in actual samples, and the recoveries results obtained were satisfactory.
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Nanoscale
·
2021
·Vol. 13
·期 31
·13473-13486
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IF 7.79
Wei Xiong,Lin Qi,Deli Si,Xin Jiang,Yu Liu,Chunjuan Zheng,Yuan Li,Jianliang Shen,Zaigang Zhou
Background: Currently, limited tumor drug permeation, poor oxygen perfusion and immunosuppressive microenvironments are the most important bottlenecks that significantly reduce the efficacy of photodynamic therapy (PDT). The main cause of these major bottlenecks is the platelet activation maintained abnormal tumor vessel barriers. Thus, platelet inhibition may present a new way to most effectively enhance the efficacy of PDT. However, to the best of our knowledge, few studies have validated the effectiveness of such a way in enhancing the efficacy of PDT both in vivo and in vitro. In this study, perfluoro-N-(4-methylcyclohexyl) piperidine-loaded albumin (PMP@Alb) nanoparticles were discovered, which possess excellent platelet inhibition ability. After PMP@Alb treatment, remarkably enhanced intra-tumoral drug accumulation, oxygen perfusion and T cell infiltration could be observed owing to the disrupted tumor vessel barriers. Besides, the effect of ICG@Lip mediated PDT was significantly amplified by PMP@Alb nanoparticles. It was demonstrated that PMP@Alb could be used as a useful tool to improve the efficacy of existing PDT by disrupting tumor vessel barriers through effective platelet inhibition.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Runmin Huang,Dan Liao,Zhenhua Liu,Jingang Yu,Xinyu Jiang
Construction of high-sensitive analytical platform to monitor organic pollutants in the environment is of significance. Nitrophenol is toxic organic pollutant, causing serious damage to biosphere. Herein, a simple self-assembled method was proposed to design a novel heterostructure (MXene/ ZIF) composed of Nb 2 CT X and Zn-Co-ZIFs derived bimetallic Zn, Co embedded N-doped carbon (Zn-Co-NC) nanocage. The Nb 2 CT X / Zn-Co-NC composite modified electrodes were applied for the electrochemical detection of 4-nitrophenols (4-NP). SEM images revealed that the insertion of Zn-Co-NC can effectively avoid Nb 2 CTx from restacking. EDS and XPS demonstrated the successful synthesis of bimetallic Zn, Co embedded N-doped carbon nanocage. Excellent conductivity and large specific surface area of Nb 2 CTx as well as superior catalytic activity of Zn-Co-NC nanocage enhance the electrochemical performance of Nb 2 CTx/ Zn-Co-NC sensor. Under optimal conditions, the achieved wide linear range was 1 μM to 500 μM. The low detection limit of 0.070 μM with high sensitivity of 4.65 μA μM −1 cm -2 was obtained. Furthermore, the Nb 2 CTx/ Zn-Co-NC sensor holds outstanding selectivity and stability. Therefore, the innovative structure and excellent properties of MXene/ ZIF make them alternative materials for various electrochemical sensors for the detection of other toxic organic pollutants.
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Solar RRL
·
2021
·Vol. 5
·期 8
·2100216
·
IF 8.582
Bin Xu,Xiatong Qin,Xiaoshuang Lu,Yulin Liu,Ye Chen,Hui Peng,Pingxiong Yang,Junhao Chu,Lin Sun
Cu 2 ZnSn(S,Se) 4 has been widely regarded as a promising thin-film solar cell material. In recent years, the development of Cu 2 ZnSn(S,Se) 4 solar cells has encountered a bottleneck, and the higher open-circuit voltage deficit mainly caused by the secondary phase, CZTSSe/CdS interface recombination, deep-level defects, and band-tailing effects has been an outstanding issue. Herein, the influence of the composition and phase distribution of the precursor thin film on the defect and performance of Cu 2 ZnSn(S,Se) 4 solar cells is studied. By modifying the distribution of composition and phase for precursor films, a Cu 2 ZnSn(S,Se) 4 absorber layer without secondary phase and with fewer detrimental defects can be obtained from the pure-phase precursor film. Thanks to the reduction of the band-tailing effects, the increase in the depletion width for heterojunction, and the decrease in CZTSSe/CdS interface recombination, the photovoltaic performance of CZTSSe thin-film solar cells is significantly improved. Finally, based on the excellent kesterite absorber layer, a Cu 2 ZnSn(S,Se) 4 solar cell with 11.51% power conversion efficiency (the active area efficiency is 12.4%) is prepared.
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SOLAR ENERGY
·
2021
·
IF 5.742
Junye Tong,Shaotong Wang,Gang Wang,Yue Liu,Yuxiang Wang,Liping Chen,Lingling Wang,Daocheng Pan,Xintong Zhang,Yichun Liu
Ion doping strategy is a promising method to enhance the efficiency of Cu 2 ZnSn(S,Se) 4 (CZTSSe) solar cells, however, most of the reported works focus on studying the single ion doping in CZTSSe absorber layers . Here, Li + &Ag + and Li + &Cd 2+ double-ion-doping strategy are applied to improve the microstructure and device performances. We found that the double-ion-doping strategy can obviously increase the grain size, reduce the thickness of fine-grain layers and enhance the device performances. Furthermore, the PCEs of Li + &Ag + and Li + &Cd 2+ doped CZTSSe solar cells are up to 8.87% and 8.39%, respectively. It shows an encouraging improvement of over 43.5% and 35.8% enhancement compared with the traditional method (6.18%), and significantly higher than single ion doping strategy (7.60%, 7.99% and 7.11% for Li + , Ag + , and Cd 2+ doped CZTSSe solar cells). This work provides a new solution to improve the microstructure and device performances of CZTSSe solar cells.
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Materials Chemistry Frontiers
·
2021
·Vol. 5
·期 16
·6145-6151
·
IF 6.482
Rui Zhao,Hui Peng,Faqiang Wang,Jianghong Zhen,Lu Li,Guofu Ma,Ziqiang Lei
Poly(4-aminodiphenylamine) (P(4-ADPA)) is a kind of polyaniline derivative and is promising as one of the alternatives to polyaniline because its monomer has a lower oxidation standard potential for oxidation and a faster oxidation rate than that of the aniline monomer. Herein, to explore the factors affecting the structural and electrochemical properties of novel conducting P(4-ADPA) materials, a series of P(4-ADPA) has been prepared by using different organic or inorganic proton acids as dopants and a cationic surfactant as the structure-directing agent. The result shows that the shape and stability of the self-assembled surfactant lamellar micelles are strongly affected by the species and the counter-ion size of proton acids, which in turn affects the morphology, crystallinity and the electrochemical properties of P(4-ADPA). Specifically, P(4-ADPA)-L with lactic acid as the dopant under a mild polymerization environment possesses a uniform intertwined nanosheet morphology and shows superior electrochemical properties with a high specific capacitance of 388 F g−1 at 0.5 A g−1 and a superlong cycle stability. In addition, P(4-ADPA)-S and P(4-ADPA)-P with sulfuric acid and perchloric acid as dopants, respectively, exhibit high conductivity and specific capacitance, and due to the high acidity of reaction solutions, a large size of counter-ions and thereby good crystallinity.
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JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
·
2021
·Vol. 96
·期 6
·1523-1532
·
IF 3.174
Shiting Xu,Xixi Chen,Shujuan Zhan,Shuanghong Tian,Ya Xiong
BACKGROUND To strengthen the treatment efficiency of photocatalytic ozonation, it is necessary to develop a stable bifunctional catalyst active in both processes of photocatalysis and catalytic ozonation. RESULTS A series of Fe doped CeO 2 nanocubes with the main exposure of active (100) crystal facets were simply synthesized by a one-pot hydrothermal method and applied in photocatalytic ozonation for the first time. It was found that doping did not change the morphology of nanocubes but it decreased the crystal size, induced abundant defects of oxygen vacancies and Ce 3+ , and shifted the optical absorption edge to the visible region. Due to these structure modifications, Fe doped CeO 2 nanocubes enhanced the mineralization rate of 4-chlorophenol by 55.4–74.7% and reduced the formation of carcinogenic bromate by 60.2–85.4%, depending on the doping content. Due to the simultaneous occurrence of photocatalysis, catalytic ozonation, and their synergy in 5%Fe-CeO 2 mediated photocatalytic ozonation under solar irradiation, 4-chlorophenol almost completely degraded within 9 min, 74.7% of mineralization rate was achieved within 45 min, and the first order kinetics reaction constant reached 2.97 × 10 −2 ·min −1 , about 4.1 times that of photo ozonation without any catalysts. Moreover, the introduction of 5%Fe-CeO 2 to the ozonation, photolysis, and photo ozonation decreased the corresponding energy consumption by 60.2%, 84.2%, and 62.5%, respectively. CONCLUSION In this study, an efficient and economical Fe doped CeO 2 nanocubes-mediated photocatalytic ozonation process was successfully developed for the refractory organics-containing wastewater treatment under solar light irradiation. © 2021 Society of Chemical Industry
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
·
2020
·Vol. 25
·期 2
·1140-1150
·
IF 4.486
Jie Xu,Dazhi Chen,Lanling Jin,Zhengkang Chen,Yulu Tu,Xiaozhe Huang,Feiben Xue,Jialu Xu,Mingzhuan Chen,Xiaodong Wang,Yongping Chen
Inflammation and fibrosis are major consequences of autoimmune hepatitis, however, the therapeutic mechanism remains to be investigated. USP4 is a deubiquitinating enzyme and plays an important role in tissue fibrosis and immune disease. Vialinin A is an extract from mushroom and is a specific USP4 inhibitor. However, there is lack of evidences that Vialinin A plays a role in autoimmune hepatitis. By employing S100-induced autoimmune hepatitis in mice and AML12 cell line, therapeutic mechanism of Vialinin A was examined. Inflammation was documented by liver histological staining and inflammatory cytokines. Fibrosis was demonstrated by Masson, Sirius red staining and fibrotic cytokines with western blot and real-time RT-PCR. In experimental animal, there were increases in inflammation and fibrosis as well as USP4, and which were reduced after treatment of Vialinin A. Vialinin A also reduced Rheb and phosphorylated mTOR. Moreover, in LPS-treated AML12 cells, LPS-induced USP4, inflammatory and fibrotic cytokines, phosphorylated mTOR and Rheb. Specific inhibitory siRNA of USP4 reduced USP4 level and the parameters mentioned above. In conclusion, USP4 was significantly elevated in autoimmune hepatitis mice and Vialinin A reduced USP4 level and attenuate inflammation and fibrosis in the liver. The mechanism may be related to regulation of Rheb/mTOR signalling.
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Journal of Materials Chemistry A
·
2020
·Vol. 9
·期 4
·2292-2300
·
IF 11.301
Yafang Qi,Xiaoyue Zhao,Yao Liu,Dongxing Kou,Wenhui Zhou,Zhengji Zhou,Shengjie Yuan,Yuena Meng,Sixin Wu
In Cu2ZnSn(S,Se)4 photovoltaic devices, the exceptionally high density of 2CuZn + SnZn donor defects may induce bandgap fluctuations and thus limit Voc and PCE enhancement. We have previously reported that the partial substitution of Ag for Cu in Cu2ZnSn(S,Se)4 provides a promising way to effectively suppress CuZn defects and considerably enhance the cell performance for Cu2ZnSn(S,Se)4 photovoltaic devices. However, the bandgap fluctuations and detrimental band tailing fundamentally still limit cell performance. On the basis of a Ag-substituted CZTSSe system, in this paper, we demonstrate that partially substituting Zn with Mn could be a feasible tactic to pronouncedly decrease the bandgap fluctuations and prevent detrimental band tailing. Our in-depth investigation reveals that Mn substitution could increase depletion width, decrease the defect densities of the CuZn acceptor and 2CuZn + SnZn donor, and enable grain boundary (GB) inversion in a (Cu,Ag)2ZnSn(S,Se)4-based cell. As a result, an impressive PCE of 11.81% was achieved when the Mn substitution level was 10%, with a Voc of 478 mV, a Jsc of 37.89 mA cm−2, and an FF of 65.23%. This is so far the highest efficiency among Mn-substituted CZTSSe-based photovoltaic devices. By thoroughly understanding these photoelectric properties of the CZTSSe-based photovoltaic devices, we believe that the breakthrough in device efficiency will come soon through our continuous efforts.
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