ACS Chemical Neuroscience
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2022
·
IF 5.78
Mingming Xu,Hong Jin,Zhen Wu,Ying Han,Jing Chen,Chengjie Mao,Piliang Hao,Xumin Zhang,Chun-Feng Liu,Shuang Yang
It is urgently needed to find reliable biofluid biomarkers for early diagnosis of Parkinson’s disease in order to achieve better treatment. Promising biomarkers can be found in Parkinson’s disease-related glycoproteins as aberrant protein glycosylation plays an important role in disease progression. However, current information on serum N-glycoproteomic changes in Parkinson’s disease is still limited. Here, we used glycoproteomics methods, which combine the solid-phase chemoenzymatic method, lectin affinity chromatography, and hydrophilic interaction chromatography with high-resolution mass spectrometry, to analyze the glycans, glycosites, and intact glycopeptides of serum. Increased abundance of glycans containing core fucose, sialic acid, and bisecting N-acetyl glucosamine was detected at the overall glycan level and also at specific glycosites of glycopeptides. Five Parkinson’s disease-associated proteins with this type of N-glycosylation changes were also identified. We propose that the revealed site-specific N-glycosylation changes in serum can be potential biomarkers for Parkinson’s disease.
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PubMed
高影响因子
CATALYSIS TODAY
·
2022
·
IF 6.562
Zhen Liu,Hu Li,Yi Wang,Yu Wang,Peng Peng,Xinmei Liu
Due to higher thermal and hydrothermal stability, suitable acidity properties, Beta zeolite is considered as promising catalyst for naphtha catalytic cracking process. However, high cost and environmental pollution issue limit its industrial application by using high content of N-containing organic structural directing agent (SDA). In this paper, different SiO 2 /Al 2 O 3 ratios of Beta zeolites were prepared assisting by seeds induced method with low SDA and cheap industrial silica sol as the silicon source. Physical and chemical properties of as-prepared Beta zeolites were characterized by XRD, N 2 adsorption-desorption, NH 3 -TPD, Py-FTIR and SEM. N-Heptane was used as model compound for catalytic cracking performance evaluation. The results showed that Beta zeolite with high SAR was successfully synthesized, which had well defined crystallinity, proper specific surface area and pore structure, high B/L ratio and strong acid site. n-Heptane catalytic cracking performance showed high yield of low-carbon olefins with relative low activity on hydrogen transfer reaction and coke formation.
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高影响因子
JOURNAL OF POLYMER SCIENCE
·
2022
·Vol. 60
·期 13
·1954-1961
·
IF 3.046
Jingrui Liu,Wei Sun,Zhaoqiang Wu,Hong Chen
A novel trithiocarbonate reversible addition−fragmentation chain transfer (RAFT) reagent, 3-azidopropyl (4-[fluorosulfonyl]benzyl)trithiocarbonate (Az-FSBCT), which has both clickable azidopropyl and sulfonyl fluoride moieties, was designed and synthesized. Using the RAFT agent Az-FSBCT and triethylboron as an initiator, well-defined poly( N -vinylpyrrolidone) (PVP), in which the azide and sulfonyl fluoride groups are at the α and ω positions of the polymer chains, were prepared without prior deoxygenation at room temperature. Moreover, the possibilities for the construction of new functionalized polymers were also demonstrated by a “click” copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) and sulfur(VI)-fluoride exchange (SuFEx) postreaction using these terminal functional PVPs. Graphical
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Yanning Zheng,Dapeng Xu,Lixia Sun,Junrong Ji,Jianhua Sun,Zhangfa Tong,Lingyi Qin,Youquan Zhang,Jiangxue Luo,Dankui Liao
The catalytic synergy of different nanomaterials is a potential technique used to develop a highly active and stable nanozyme . Here, magnetite on nitrogen-doped hollow carbon sphere (Fe 3 O 4 /N-HCS) composites were prepared through solvent thermal method and exhibited excellent oxidase and peroxidase-like catalytic activity under different pH levels. The dual enzyme-like catalyzed reaction of Fe 3 O 4 /N-HCS conformed to the typical Michaelis–Menten kinetics, and Fe 3 O 4 /N-HCS had a strong affinity for substrate 3,3′,5,5′-tetramethylbenzidine (TMB) with H 2 O 2 . The remarkable performance of the composites was achieved by the synergistic effect of Fe 3 O 4 and N-doped activated graphite carbon, which accelerated the formation of O 2 •- and •OH during the dual enzyme-like catalytic reaction . Furthermore, an effective colorimetric glutathione (GSH) sensor with a wide linear range from 0.02 µM to 250 µM and a detection limit as low as 9.3 nM was constructed based on the superior peroxidase-like activity of Fe 3 O 4 /N-HCS. The convenient colorimetric sensor monitored the content of GSH in the serum of mice, and the detection results were satisfactory, with a recovery of 96–103% and an RSD between 0.80% and 3.30%. This study discussed the internal mechanism of Fe 3 O 4 /N-HCS nanozyme and developed an efficient method for GSH detection to expand nanozyme application in bioanalysis .
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高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Yifan Song,Tianyu Zhang,Guangda Zhou,Peizhi Liu,Xiaoli Yan,Bingshe Xu,Junjie Guo
Earth-rich transition metal-based catalysts are considered to be the most promising candidates to alternate noble metal-based electrocatalysts for oxygen reduction reaction (ORR). Nevertheless, the practical applications have been hampered due to their poor electrocatalytic behaviors and stability. Here, we report the facial thesis of Cu nanoclusters supported on N-doped carbon nanotubes by a simple grinding and heat treatment method, which presented a superior electrocatalytic performance than commercial Pt/C. In alkaline media, an onset potential (E 0 ) and half-wave potential (E 1/2 ) of 0.98 V and 0.88 V (RHE) have been achieved, respectively. In addition, the synthesized catalysts present a good tolerance and long-term stability to methanol, and exhibit less than 7% H 2 O 2 formation. It is inferred that the enhanced electrocatalytic behavior could be attributed to the formation of Cu-N X active sites, which are coupled into the nitrogen-rich carbon nanotubes. This low-cost, extremely durable and stable electrocatalyst showed a great potential as an efficient cathode material for a variety of renewable energy conversion technologies, such as fuel cells and metal-air cells.
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高影响因子
NEW JOURNAL OF CHEMISTRY
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2022
·Vol. 46
·期 11
·5312-5320
·
IF 3.925
Keping Wang,Mei Wu,Yixuan Liu,Ying Yang,Hu Li
Five-membered nitrogen heterocyclic pyrroles have extremely high physiological activity and are widely used in medicine, agriculture, materials chemistry, industry, and supramolecular chemistry. Developing a mild and eco-friendly way to synthesize functionalized pyrroles from biologically derived materials is desirable. In this study, biomass-derived 2,5-dimethylfuran can react with a series of aromatic amines to synthesize 2,5-dimethyl-N-arylpyrroles through acid-enabled ring-opening and Paal–Knorr condensation in one pot. Among the tested acid catalytic materials, a new magnetic biocarbon-based sulfonic acid solid catalyst (WK-SO3H) showed excellent catalytic performance in the synthesis of N-substituted pyrroles (up to ca. 90% yield) and was easy to separate and recover by an external magnetic field. The ring-opening of furan proved to be the rate-determining step of the above one-pot multi-step conversion process, and 2,5-hexanedione is a key intermediate for the cascade reaction, while the addition of water could significantly enhance the above-mentioned ring-opening reaction. Furthermore, multiple characterization methods (e.g., FT-IR, TGA, XRD, NH3-TPD, and XPS) confirmed that WK-SO3H has good stability in the aqueous reaction system.
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高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Hanxiao Zhou,Huimin Shang,Tianhui Li,Wenjing Liu,Zhihao Guo,Yuxuan Guo,Jingjing Gao,Meizhen Qu,Huan Zhang,Gongchang Peng
Lithium anodes have attracted much attention because of their high energy density, but the existence of lithium dendrites tremendously limits their practical application. Herein, it is creatively proposed to employ N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) as an electrolyte additive to stabilize the solid electrolyte interface. BSTFA is reduced on the lithium anode surface prior to other components to form a passivation layer composed of LiF, Li3N, and SiOx, which not only significantly prevents the continuous consumption of the electrolyte and reduces side reactions but also effectively promotes the uniform deposition of lithium ions with fast Li+ transmission, thereby solving the problem of lithium dendrites. Electrochemical results indicate that BSTFA can obviously reduce polarization in a Li||Li battery at a current density of 1 mA cm–2. Besides, an excellent cycling performance (107 mA h g–1) and Coulombic efficiency (99%) can be obtained for a Li||LiNi0.6Co0.2Mn0.2O2 (NCM622) battery with 0.5 wt % BSTFA at 2 C after 200 cycles, even at a high NCM622 loading of 6 mg cm–2.
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高影响因子
POLYMER
·
2022
·
IF 4.432
Junping Lv,Lin Zhu,Meng Zhang,Zexu Zhao,Shu-Wei Chen,Jinyi Wang
Actuators with controllable and reversible morphing towards environment stimuli have great potential applications in diverse fields. In spite of good progress made over the past decades, simple and efficient preparation of multi-response actuators is still a challenge. Here, we report a strategy to prepare humidity and near infrared (NIR) dual-response actuators with controllable and reversible bending or twisting deformation. The actuators were made up of two layers, one was polyvinyl butyral (PVB) layer with humidity and NIR inertness, and the other was chlorine-modified polypyrrole (PPy-Cl) doped poly(N-isopropylacrylamide-co-benzophenone) (PNIPAM-ABP) composite layer, taking advantage of the NIR photothermal conversion capability of PPy-Cl, along with the thermal-responsive PNIPAM-ABP. Upon NIR light irradiation , PPy-Cl converted light energy into heat, which subsequently induced the shrinkage of poly(N-isopropylacrylamide) (PNIPAM) chains; upon a high-humidity environment, PPy-Cl absorbed water molecular and transferred it into PNIPAM polymer , which further caused the bilayer to shrink or swell in an asymmetric manner, consequently leading to reversible bending or unbending behaviors. Interestingly, upon ultraviolet (UV) light irradiation with a grid photomask, the bilayer actuators showed bending or twist behaviors along with a special direction. The bionic flowers made from the actuators could imitate sunflower's opening and closing behaviors in response to NIR or humidity. The dual-response actuator could also imitate the lifting weight behaviors of forklifts. As an interesting example for potential utilization, a smart four-wheel vehicle was constructed using the bilayer actuator, showed excellent fast-moving performance.
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高影响因子
Separations
·
2022
·Vol. 9
·期 3
·64
·
IF 3.344
Weibin Cai,Jiangyu Xie,Jingyu Luo,Xiaohan Chen,Mingqian Wang,Yujun Wang,Jiding Li
In this study, zeolite molecular sieve SAPO-34/polydimethylsiloxane (PDMS) mixed matrix membranes (MMMs) were prepared to recover propane. n-Octyltrichlorosilane (OTCS) was introduced to improve compatibility between SAPO-34 and PDMS, and enhance the separation performance of the MMMs. Physicochemical properties of the MMMs were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and water contact angle (WCA). Results showed that, after modification, alkyl chains were successfully grafted onto SAPO-34 without changing its crystal structure, particles in the MMMs were evenly distributed in the base film, and the hydrophobicity of the MMMs was enhanced. Moreover, the effects of SAPO-34 filling content, operating pressure, and feed gas concentration on the separation performance was explored. This indicated that the modification with OTCS effectively enhanced the separation performance of SAPO-34/PDMS MMMs. When the filling content of modified SAPO-34 was 15%, the maximal separation factor of 22.1 was achieved, and the corresponding propane permeation rate was 101 GPU.Keywords:MMMs;SAPO-34;PDMS;OTCS;propane recovery
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高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2022
·
IF 8.91
Guangyu Duan,Zhanfang Cao,Hong Zhong,Xin Ma,Shuai Wang
Heavy metal wastewater pollution has become an ecological challenge worldwide. This study reports the development of a novel poly (6-acryloylamino-N-hydroxyhexanamide) (PAHHA) resin for effective adsorption of heavy metal ions , including Cu 2+ , Pb 2+ and Ni 2+ . The chelating resin was synthesized by the grafting reaction between 6-amino-N-hydroxyhexanamide and polyacrylic resin , thus containing the hydroxamate and acylamino groups. The batch adsorption experiments revealed that the PAHHA resin exhibited an excellent adsorption performance for Cu 2+ , Pb 2+ and Ni 2+ . The maximum adsorption capacities of Cu 2+ , Pb 2+ and Ni 2+ were determined to be 238.59, 232.48 and 115.77 mg·g −1 , respectively. Based on the adsorption kinetics , the pseudo-second-order kinetic model was noted to fit well for all metal ions. The metal ion concentration as a function of the equilibrium adsorption capacity fitted well with the Langmuir isotherm , thus indicating the single layer adsorption process . The adsorption mechanism was investigated by using Fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), density functional theory (DFT) calculations, X-ray photoelectron spectroscopy (XPS) and adsorption isotherms . It was revealed that the PAHHA resin possessed multiple active sites, including –CONHOH, –CONH– and –COOH, which could strongly adsorb the metal ions. Specifically, the –CONHOH group displayed a high affinity by forming a stable five-membered ring with heavy metal ions. Overall, the developed resin exhibits advantages such as simple synthesis, inexpensive raw material and good recyclability , along with high adsorption ability, thus providing a new approach for efficiently treating wastewater contaminated with heavy metal ions.
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高影响因子
POLYMER
·
2022
·
IF 4.432
Chenghao Li,Jingye Sun,Ulla Sana,Yongjun Ma,Xianyan Ren,Cailin Liu
Herein, carbon dots (CDs) and N,N-dimethylaniline (DMA) were designed as a redox couple for redox-initiated polymerization of N-vinylcarbazole (NVC) under mild conditions. Several ratios of CDs to DMA and various temperatures were adopted to prove the feasibilities of the redox-initiated polymerization. Meanwhile, the CDs as fillers were encapsulated, crosslinked and passivated by the resulting poly (N-vinylcarbazole) (PVK) to form red emissive PVK-CDs composites with a fluorescence quantum yield up to 28.75%, which is significantly higher than that of pristine CDs. In particular, the loading of CDs also enhanced the electron-transfer properties and thermostability of PVK. Hence, this work not only applied CDs to redox-initiated polymerization of NVC so as to prepare CDs modified PVK, but also illustrated the electron-transfer properties of CDs in polymerization and PVK modification. Expectedly, by taking advantages of electron-transfer properties of CDs, it is expectable for redox-initiated polymerization to synthesize more CDs modified polymers for promising applications.
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高影响因子
POLYMER DEGRADATION AND STABILITY
·
2022
·
IF 5.204
Wentao He,Huahui Xu,Pingan Song,Yushu Xiang,Shuhao Qin
Flame-retardant functionalized nanomaterials have attracted much research interests due to the combined advantages of organic and inorganic components. In the present study, P, N-decorated halloysite nanotube (MA-PPA@HNT) was prepared via simple steps of phenphosphinic acid intercalation and subsequent electrostatic interaction with melamine. Compared to unmodified HNT, the incorporation of MA-PPA@HNT into polyamide 6 (PA6)/aluminum diethylphosphinic acid (AlPi) composite results in significant improvement of flame retardancy. At equal HNT loading of 2wt%, the UL-94 rating grade of PA6/AlPi/MA-PPA@HNT composite was V-0, whereas that of PA6/AlPi/HNT composite V-2. And compared with PA6 , there is a decrease of peak heat release rate (pHRR) and total heat release (THR) by 72.6% and 17.4%, respectively. The flame retardant mechanism was analyzed by cone calorimetry, gas volatility and characterization of char residues. It is considered that MA-PPA@HNT plays the critical role of promoting the formation of P, Si-rich intumescent char in the condensed phase and enhancing the barrier effect for heat and mass transfer.
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