Environmental Science-Nano
·
2022
·Vol. 9
·期 7
·2572-2586
·
IF 9.473
Wen Chen,Xiang Ye,Qiong Tang,Ting Yu,Pengcheng Tu,Xiaodong Zheng
Nano-plastic pollution has been increasingly recognized as a key environmental issue. Nano-plastic exposure is linked to a multitude of environmental and health effects, and we have previously reported that cyanidin-3-O-glucoside (C3G) promoted discharge and reduced the biotoxicity of polystyrene (PS). This study further determines the impact of C3G on PS exposure, and investigates the role of energy metabolism in the ameliorative effects of C3G. Through a Caenorhabditis elegans (C. elegans) model, C3G was discovered to be capable of promoting discharge and alleviating biotoxicity induced by environment-relevant PS exposure. C3G was also found to restore PS-induced ATP reduction accompanied by improved mitochondrial dysfunction, suggesting involvement of energy metabolism. Using a Caco-2 cell model, we found that the molecular mechanism involves C3G protecting against PS-induced ATP reduction by activating the AMPK/SIRT1/PGC-1α signaling pathway. C3G-mediated ATP production and mitochondrial functions, which improve the activity of ABC transporters and cellular efflux of PS, may constitute the primary toxicity-alleviating mechanism through which C3G acts. Furthermore, in a mouse model administered with PS, it was discovered that C3G activates the AMPK/SIRT1/PGC-1α signaling pathway regulating the ATP level in colon tissue, in addition to the increased fecal PS discharge. These findings suggest that C3G protects against adverse effects of PS exposure on multiple organism models, and the underlying mechanism involves mitochondria-related energy metabolism and efflux.
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Food & Function
·
2021
·Vol. 12
·期 18
·8351-8365
·
IF 5.396
Yonglu Li,Xin Yu,Yaxuan Wang,Xiaodong Zheng,Qiang Chu
Lung cancer has been threatening human health worldwide for a long time. However, the clinic therapies remain unsatisfactory. In this study, the anti-adenocarcinoma lung cancer A549 cell line abilities of Tetrastigma hemsleyanum tuber flavonoids (THTF) were evaluated in vivo, and isobaric tags for relative and absolute quantification (iTRAQ)-based proteomic analysis was conducted to detect the protein alterations in THTF-treated solid tumors. The differentially expressed proteins were related to the cytoskeleton and mostly accumulated in the calcium signaling pathway. The in vitro study illustrated that 80 μg mL−1 THTF significantly suppressed cellular viability to approximately 75% of the control. Further results suggested that kaempferol-3-O-rutinoside (K3R), the major component of THTF, effectively triggered cytoskeleton collapse, mitochondrial dysfunction and consequent calcium overload to achieve apoptosis, which remained consistent with proteomic results. This study uncovers a new mechanism for THTF anti-tumor ability, and suggests THTF and K3R as promising anti-cancer agents, providing new ideas and possible strategies for future anti-lung cancer prevention and therapy.
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ACS Applied Optical Materials
·
2025
·
IF 3.8
Lipeng Huang,Yanjie Liang,Xulong Lv,Xihui Shan,Yi Zhang,Xiao-Jun Wang
Short-wave infrared (SWIR) light sources, as crucial components of SWIR imaging and spectroscopy technologies, have garnered significant attention recently. The rapid development of portable electronic devices has created a demand for compact and efficient SWIR emitters, and phosphor-converted SWIR LEDs represent the optimal technological solution to meet this requirement. Here, a Cr(PO3)3:Yb3+ phosphor with highly efficient and pure SWIR luminescence under 450 nm blue LED excitation is reported. Upon doping with Yb3+ in the Cr(PO3)3 matrix, the resulting material is capable of effectively converting blue excitation photons to SWIR luminescence spanning from 900 to 1200 nm, with a dominant emission peak at 1003 nm due to the efficient energy transfer from Cr3+ to Yb3+. Notably, this phosphor demonstrates an ultrahigh internal quantum efficiency (IQE) of 95.7% and a record external quantum efficiency (EQE) of 60.3% upon 450 nm blue light excitation. Moreover, the fabricated SWIR LED prototype device by combining the Cr(PO3)3:Yb3+ phosphor and a commercial 450 nm blue LED chip exhibits SWIR output power of 24.1 mW at 200 mA input current and a photoelectric conversion efficiency of 12.8% at 20 mA. This study not only opens avenues for realizing high-efficiency SWIR luminescence by deliberately controlling energy transfer pathways in Cr-based material systems but also paves the way for the development of high-power SWIR light sources.
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ANALYST
·
2013
·Vol. 138
·期 6
·1851-1857
·
IF 3.969
Huanshun Yin,Zhenning Xu,Yunlei Zhou,Mo Wang,Shiyun Ai
A label-free electrochemical immunosensor for ultra-sensitive detection of indole-3-acetic acid (IAA), a very important phytohormone, has been developed in this work. The detection strategy was mainly based on 4-aminophenylboronic acid, magnetic nanoparticles functionalized with horseradish peroxidase-conjugated goat anti-rat immunoglobulin G (HRP-IgG-Fe3O4) and rat monoclonal antibody against IAA-modified gold nanoparticles (anti-IAA-AuNPs). HRP-IgG-AuNPs was covalently assembled on the electrode surface through the specific chemical reaction between boronic acid and the vicinal diol in HRP-IgG. Then, anti-IAA-AuNPs was further assembled on the electrode via the interaction between IgG and antibody. Through the dual amplification of HRP-IgG-Fe3O4 and anti-IAA-AuNPs, the trapping capacity of the immunosensor for IAA was significantly enhanced based on the promotion of the immunoreaction between antibody and antigen, which resulted in a large decrease of the electrochemical response of the redox probe, Fe(CN)63−, and an increase in sensitivity. The developed electrochemical immunosensor exhibited a wide linear range from 0.02 to 500 ng mL−1 with a low detection limit of 0.018 ng mL−1 (S/N = 3). Moreover, the proposed immunosensor showed acceptable selectivity, reproducibility, accuracy and stability. The IAA extracted from various seeds was successfully detected using the developed immunosensor. This assay method might provide an alternative strategy for the detection of various phytohormones.
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CATALYSIS TODAY
·
2025
·
IF 5.3
Yaoyi Hu,Xiqiang Yuan,Zhengquan Zhang,Yu Zhang,Han Ma,Yunfei He,Shaoyun Shan,Tianding Hu
Natural borneol has enormous medicinal value (like clearing heat, detoxifying, relieving pain, and other effects) but has a low yield and high price. Compared with the natural extraction method to obtain borneol, a synthetic method has significant advantages such as high yield, environmental protection, and high economic benefits. In the synthesis method, the catalyst is the most key factor. In this study, two catalysts (SO 4 2- /ZrO 2 -TiO 2 and Al 2 (SO 4 ) 3 /ZrO 2 -TiO 2 ) with high catalytic performance and high positive selectivity were synthesized by impregnation method to synthesize borneol from α-pinene. The optimum synthesis conditions of SO 4 2- /ZrO 2 -TiO 2 were as follows: n(Zr): n(Ti) = 3: 1, sulfuric acid concentration 2 mol/L, calcination temperature 550 °C, the yield of borneol was 68.14 %. Based on the preparation of catalyst SO 4 2- /ZrO 2 -TiO 2 , the optimum synthesis conditions of Al 2 (SO 4 ) 3 /ZrO 2 -TiO 2 were as follows: the concentration of aluminum sulfate was 0.4 mol/L, the calcination temperature was 600 °C, and the yield of borneol was 74.58%, Compared with the highest yield of 59.89% reported in the existing literature, the performance is improved by 13.96%. In addition, the mechanism of the esterification and saponification reaction of borneol has been in the blank stage. We used the density functional theory (DFT) to explore the reaction mechanism.
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WATER RESEARCH
·
2025
·
IF 12.4
Jung-Hyun Son,Wen-Long Wang,Peng-Hui Liu,Hang Su,Ju-Won Lee,Min-Yong Lee,Qian-Yuan Wu
This study investigates the enhancement of ozonation efficiency through the introduction of manganese ions (O 3 /Mn(II)) that significantly improve the degradation of ozone-persistent organic pollutants. Manganese ions accelerate hydroxyl radical generation by catalyzing ozone decomposition, thereby facilitating more effective oxidative reactions. The application of O 3 /Mn(II) to degrade N, N-Diethyl-3-toluamide (DEET) achieved a decomposition efficiency of 3.6 to 4.1 times higher than ozonation alone. The promotive effect was highly pH-dependent, with the observed rate constant ( k obs ) for O 3 /Mn(II) reaching 97.05 M −1 s −1 at pH 4, approximately 3.3 times greater than ozonation alone, and 686.93 M −1 s −1 at pH 7, around 1.7 times higher. O 3 oxidation contributed approximately 1% to the overall process, while hydroxyl radicals accounted for approximately 80%, and manganese species accounted for approximately 20%. Furthermore, the oxidation state of manganese significantly influenced the cooperative oxidation efficiency, with Mn(VII) achieving the highest k obs (680.87 M −1 s −1 ), while Mn(IV) exhibited the lowest (304.6 M −1 s −1 ). Additionally, intermediate products formed during DEET oxidation were identified using Orbitrap technology, elucidating various degradation pathways (such as decarboxylation, tri-hydration, and aromatic ring opening). These findings provide valuable insights into enhancing ozonation processes for environmental remediation.
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CARBOHYDRATE POLYMERS
·
2010
·Vol. 83
·期 4
·1631-1635
·
IF 3.167
Kun Huang,Jianling Xia,Mei Li,Jianwei Lian,Xiaohua Yang,Guifu Lin
Cellulose stearates with different degrees of substitution (DS) were prepared homogeneously in ionic liquid 1-butyl-3-methylimidazolium chloride ([C 4 mim] + Cl − ) solution. Cellulose stearates with DS values of 2.15, 2.19 and 2.57 exhibited good solubility in nonpolar organic solvents . It was indicated by differential scanning calorimetry (DSC) that the melting temperatures of the three cellulose stearates ranged from 38.66 to 56.63 °C. Thermogravimetric (TG) analysis showed that the commencing degradation temperature of the three cellulose stearates were 300 °C, 325 °C and 370 °C, respectively. The cellulose stearate with the DS value of 2.57 has better thermal stability than cellulose.
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Journal of Materials Chemistry C
·
2021
·Vol. 9
·期 10
·3672-3681
·
IF 7.393
Sheng Wu,Puxian Xiong,Xiaoqi Liu,Yubin Fu,Quan Liu,Yang Chao,Quan Dong,Yuanyuan Li,Weiwei Chen,Yan Chen,Zhijun Ma,Mingying Peng
In this study, a blue fluorescent material Sr3Y(BO3)3:Bi3+ was synthesized by the high temperature solid-state reaction method. The corresponding structural characteristics, concentration and temperature dependent luminescence characteristics of Sr3Y(BO3)3:Bi3+ and the LED device performances were systematically studied. At different excitation wavelengths in the range of 340–375 nm, the photoluminescence (PL) region can be adjusted from green (CIE: (0.2524, 0.4063); Peak: 511 nm) to blue (CIE: (0.1936, 0.1236); Peak: 415 nm). The best excitation peaked at ∼370 nm, which well matches with the emission of a commercial near-ultraviolet (NUV) light-emitting diode (LED) chip. The thermal quenching experiment was performed, and the activation energy was calculated as 0.23 eV. At high temperature, the Sr2.55Y(BO3)3:0.45Bi3+ phosphor presented good thermal stability (79.99% of RT emission intensity at 420 K). LED devices (chip: 370 nm) using the Sr2.55Y(BO3)3:0.45Bi3+ phosphor as a fluorescent material showed excellent electroluminescence performance. Under a driving current of 20 mA, the devices showed CIE coordinates of (0.3842, 0.3980), a correlated color temperature (CCT) of 4053 K and a high color rendering index (Ra) of 91.6. This work demonstrates that Sr3Y(BO3)3:Bi3+ is a promising NUV excited blue fluorescent material which shows advantage in white light-emitting diodes for solid-state lighting.
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JOURNAL OF MEMBRANE SCIENCE
·
2013
·
IF 4.093
Wen-hao Luo,Lian-hua Zhao
New silicon source (3-glycidyloxypropyltrimethoxysilane (GPTMS)) was used to make non-glass inorganic–organic hybrid membranes with diethylethylammonium trifluoromethanesulfonate ([dema][TfO]) by the sol–gel method. The hybrid membranes were studied with respect to their structural, thermal, proton conductivity and pores properties. The Fourier transform infrared spectroscopy (FT-IR) results showed that there was intermolecular interaction between ionic liquid and Si–O–Si skeleton structure in the inorganic–organic hybrid membranes. The thermogravimetric (TG) and differential scanning calorimetry (DSC) analysis showed that the hybrid membranes displayed good chemical stability and were thermally stable up to more than 200 °C in air. The N 2 adsorption test showed the hybrid membranes had good pore property and ionic liquid influenced the structure of hybrid membrane. Proton conductivity was measured from 20 °C to 220 °C and high conductivity of 1.2×10 −2 S/cm was obtained for a 60 wt% [dema][TfO] doped hybrid membrane (ionogel) at 220 °C under anhydrous conditions. This method for the preparation of hybrid membranes is promising and may be used for the proton exchange membrane in fuel cells.
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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2025
·
IF 3.5
Boruo Yang,Mei Lan,Jin Liu,XuanYi Liu,Weihao Xiong,Luan Lin,Min Zhang,Peng Liang
BACKGROUND Triglyceride-type n-3 polyunsaturated fatty acids (n-3 PUFAs) are often used to improve the quality of meat products, while the potential of phospholipid-type n-3 PUFAs remains underexplored. This study evaluated the gel and flavor quality of minced pork gel (MPG) with marine-sourced large yellow croaker roe phospholipids (LYPLs) as phospholipid-type n-3 PUFA supplements. RESULTS The addition of LYPLs increased the n-3 PUFA content in MPG and caused no visually significant color changes. Textural properties, water-holding capacity and binding water percentage increased with the incorporation of LYPLs, with the best MPG quality obtained at 1.6% LYPLs. The addition of LYPLs enriched flavor compounds such as aldehydes, ketones and alcohols in MPG while enhancing the perception of saltiness and freshness of MPG. CONCLUSION LYPLs can be successfully applied as a potential n-3 PUFA supplementation in gel-form meat products and subsequently improve their quality and flavor attributes. This study informs using LYPLs as phospholipid-type n-3 PUFA supplements in meat products. © 2025 Society of Chemical Industry.
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Light-Science & Applications
·
2026
·Vol. 15
·期 1
·135
·
IF 24
Maimaitizi Hujiabudula,Ågren Hans,Chen Guanying
The development of pure-blue perovskite light-emitting diodes (PeLEDs) still lags behind that of green and red-emitting PeLEDs. Mixed halide (Br/Cl) perovskite nanocrystals (PeNCs) are commonly employed for blue emission but suffer from halide vacancies and ion migration. Here, we present a passivation strategy using the multifunctional fluorinated phosphonic acid molecule (1H,1H,2H,2H-heptadecafluorodec-1-yl)phosphonic acid (HFPA), which possesses active functional groups that improve the stability and electroluminescence performance of CsPb(Br/Cl) 3 NCs. The HFPA molecule is shown to interact with uncoordinated Pb 2+ on the PeNC surface through the phosphonate groups, concurrently establishing hydrogen bonds with adjacent halide ions. Moreover, the presence of fluorine atoms promotes ionic bond formation with the halide octahedra, thereby stabilizing the octahedral structure. The fabricated PeNC-LEDs exhibited a spectrally stable pure-blue emission peak at 467 nm, achieving a significantly improved external quantum efficiency (14.8%, 9-fold higher), maximum luminance (1052 cd·m -2 , 10-fold higher), and half-life (342 s, 13-fold higher) compared to the device fabricated with unmodified CsPb(Br/Cl) 3 NCs. Furthermore, the effective passivation of surface vacancies and stabilization of halogen ions by the HFPA molecules successfully suppressed ion migration in the PeNC-LEDs, thereby significantly enhancing the stability of the device.
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JOURNAL OF BIOTECHNOLOGY
·
2026
·
IF 4
Malik Jan,Kashif Hayat,Israr Khan,Aadil Ahmed Memon,Ibrar Khan
The new metabolite 3-hydroxyphenazine 1-carboxylic acid (3-OH-PCA) was obtained by Aspergillus sclerotiorum ASJ82 whole-cell biocatalysis of phenazine 1-carboxylic acid. Despite the biotechnological perspective, the lack of favorable methods for 3-OH-PCA separation and purification from complex biotransformation media has considerably hampered further experimental studies for large-scale industrial applications because of insufficient amounts of purified compounds. In this context, the present work aimed to develop a simple and proficient technique for the separation and purification of 3-OH-PCA from the crude extraction and culture medium of A. sclerotiorum ASJ82. The static adsorption and desorption characteristics of five macroporous resins were evaluated, namely, HP-20, HZ-818, HZ-801, D001, and D155. Remarkably, compared with the other resins, the HZ-818 resins exhibited notable advantages in the adsorption and desorption of 3-OH-PCA. Additionally, the equilibrium adsorption data of the HZ-818 resins were assessed via the Langmuir and Freundlich isotherm models. The analysis revealed that the experimental data exhibited a favorable fit with the Langmuir isotherm model, providing valuable insights into the adsorption behavior of 3-OH-PCA on the HZ-818 resins. Furthermore, a chromatographic column packed with HZ-818 resins was employed, and dynamic adsorption and desorption experiments were conducted. These tests aimed to establish and optimize the operational parameters required to effectively separate and purify 3-OH-PCA. Under the optimized separation and purification conditions, the average adsorption capacity and desorption ratio of 3-OH-PCA were 21.1 ± 1.2 mg/g dry resin and 88 ± 1.2 %, respectively. After treatment with HZ-818 resin, the 3-OH-PCA content considerably increased. These findings revealed that the purity of 3-OH-PCA was 96.5 ± 2.1 %, whereas the recovery rate was 85.32 ± 1.2 %. The results indicate that the HZ-818 resin has significant potential as an adsorbent for effectively separating and purifying 3-OH-PCA from complex media. Overall, this methodology demonstrates great promise for achieving high yields in the separation and purification of 3-OH-PCA and could be utilized in the large-scale production of 3-OH-PCA purification from A. sclerotiorum ASJ82 extracts in industry, presenting an avenue for further investigation and application.
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