MACROMOLECULAR BIOSCIENCE
·
2026
·Vol. 26
·期 9
·e70258
·
IF 4.2
Yue Yu,Chengde Liu,Yizheng Li,Zihan Ma,Jian Xu,Xigao Jian
The treatment of osteoporotic bone defects remains challenging due to the pathological microenvironment with impaired regenerative capacity and imbalanced bone formation and resorption. In this study, a methacrylated gelatin (GelMA) and methacrylated chitosan (CSMA) composite hydrogel coating is developed on poly(phthalazinone ether nitrile ketone) (PPENK), showing pro‐osteogenic and anti‐osteoclastic effects in vitro. Nano‐zinc oxide (nano‐ZnO), nano‐hydroxyapatite (nano‐HA), and phosphate‐ester‐functionalized alendronate (ALNP) are incorporated to confer antibacterial activity, promote osteogenesis, and enable enzyme‐responsive release of anti‐osteoporosis alendronate (ALN). SEM/EDS results confirm the homogeneous dispersion of the nanoparticles within the porous hydrogel. The stability of the hydrogel coating is verified by smooth scratch edges and no visible detachment in the cross‐hatch test. ALN release experiments confirm that the release amount of ALN is positively correlated with alkaline phosphatase (ALP) concentration, indicating significant enzyme‐responsive characteristics. In vitro studies show that the hydrogel coating on PPENK exhibits antibacterial activity. Nano‐HA and nano‐ZnO enhance the expression of osteogenic‐related genes and proteins in MC3T3‐E1 pre‐osteoblasts. The released ALN inhibits the receptor activator of nuclear factor‐κB ligand (RANKL)‐induced differentiation of RAW264.7 macrophages into osteoclasts. Overall, this surface modification strategy integrates enzyme‐responsive ALN release with composite hydrogel coating on PPENK, realizing antibacterial, osteogenic, and anti‐osteoclastic effects in vitro. This study reports a methacrylated gelatin/methacrylated chitosan/nano‐HA/nano‐ZnO/phosphate‐ester‐functionalized alendronate hydrogel coating on vinyl‐modified PPENK (G/C/H/Z/A@PPENK‐DB). The composite hydrogel coating enables enzyme‐responsive release of the anti‐osteoporotic drug alendronate via hydrolysis of phosphate ester bonds by alkaline phosphatase. In vitro tests confirm its favorable antibacterial, osteogenic, and anti‐osteoclastic effects, showing great potential for the repair of osteoporotic bone defects.
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PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Mei Chen,Xu Li,Yinxiang Li,Yanhu Li,Ziyu Qin,Qingji Wang
ZnO nanoflower was directly fabricated on ceramic and then Co 3 O 4 was grown in-situ on ZnO nanoflower by a MOF-derived method. Co 3 O 4 nanoparticles were successfully coated on the surface of ZnO nanoflower to develop a sensor for the detection of carbon monoxide . Notably, the Co 3 O 4 /ZnO sensor exhibits an outstanding response of 38 % to 100 ppm CO at 210 ℃ with a fast response/recovery time (38 s/50 s). In addition, the sensor showed excellent selectivity for CO, which is 14 times better than for the second gas (500 ppm CO and NH 3 ). In the meantime, the sensor's response remained a stable value when the 100 ppm CO is mixed with 100 ppm H 2 , CH 4 and HN 3 , respectively. The prominent CO sensing performance of the sensor is attributed to its unique structure charaterastics of nanoflower and the constructed heterostructure , which provides a large surface area and abundant active sites. Therefore, the sensor based on MOF-derived Co 3 O 4 nanoparticles directly on ZnO nanoflower have promising application for constructing high performance CO sensor in the detection domain.
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Surfaces and Interfaces
·
2023
·
IF 6.2
Xinhai Li,Ruixia Jin,Min Liu,Haiming Xu,Xiaoman Yu,Xinyi Xie
Boosting photo-Fenton performance by enhancing mass transfer process of peroxy sulphate (PS) and inhibiting the recombination of photo-generation carriers is an appealing strategy. Herein, ZnO/BiOCl porous microsphere assembled by thin nanosheets was successfully fabricated via microwave-assistant method. The results discern that BOZ-30 can eliminate 75.2 % carbamazepine (CBZ, 2.5 mg L −1 ) in 180 min, which is 1.7 and 1.3 times folder than ZnO and BiOCl, respectively. Moreover, the catalytic mechanism revealed that 3D axial channels and interfacial oxygen vacancies (IOVs) enhance mass transfer process of PS, promote forming of BOZ-PS* complex, and boost the separation efficiency of photo-generated carriers. Therefore, myriad electrons are quickly arrived at surface active sites through thin nanosheets and trapped by BOZ-PS* composites, and then effectively transfer to CBZ. Eventually, PS was activated under the synergistic of IOVs and 3D axial channels. Furthermore, the structure-properties relationship of removal rate, specific area and total oxygen vacancies was established. This work shed a new light on to remove refractory pollution by the cooperation of defect engineering and morphology engineering.
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高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Kaida Kuang,Ya Li,Yu Ji,Yang Liu,Nengqin Jia
In this work, a quenched molecularly imprinting-electrochemiluminescence (MIP-ECL) sensor based on Ru(bpy) 3 2+ @ZnO-Au nanocomposites was constructed to realize the sensitive detection of acrylamide (AM). Ru(bpy) 3 2+ @ZnO-Au nanomaterials show high ECL efficiency. AuNPs has excellent properties and can improve the properties of electrochemiluminescence by promoting the electron transfer process of the luminescent body. The MIP polymer film was formed on the surface of the material and eluted with eluent, leaving an AM imprinting cavity as a specific recognition site. When adding different concentrations of AM, it was specifically recognized by the MIP membrane, and the ECL signal decreased gradually, thus realizing the sensitive detection of AM. Under the optimal conditions, the detection ranges of the MIP-ECL sensor are 1–10 8 nM and the limit of detection (LOD) is 0.123 nM. Therefore, this sensor proposed in this work opens up a new way for the sensitive detection of AM in food.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Shuaishuai Liu,Junhao Jiang,Chengzhao Jin,Ruixve Sun,Zengming Man,Pengxin Li,Kun Chang
Constructing Z-scheme heterojunctions by establishing a unique charge transfer pathway at the interface has garnered growing attention in photocatalytic technology. In this study, a p-n heterojunction of Z-scheme was developed by employing an in-situ annealing strategy following the electrostatic self-assembled chemistry, with n-type ZnO and p-type Bi 2 O 3 as the constituent materials. Upon AM 1.5 G irradiation, the optimal ZnO/Bi 2 O 3 (Zn/BO) photocatalysts achieved a remarkable H 2 -evolution reaction (HER) rate of 458.3 μmol∙h −1 , which was 10.5 times higher than that of the original ZnO and 5 times higher than that of Bi 2 O 3 , respectively. Moreover, its efficiency in degrading 100 mg∙L −1 rhodamine B (RhB) reached 100% within a 60-minute period. Its rate constant was 24.70 and 11.71 times higher compared to ZnO and Bi 2 O 3 , respectively. The proposed Z-scheme mechanism of electron transfer was put forward to explain the observed enhancement in photocatalytic performance, as determined by in-situ XPS experiments. Furthermore, the Zn/BO photocatalyst exhibited exceptional catalytic activity when exposed to visible light (λ > 420 nm). The remarkable cycle stability of the hollow Z-scheme catalyst further suggests its potential for facilitating the industrialization of photocatalytic technology.
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MOLECULES
·
2023
·Vol. 28
·期 20
·7034
·
IF 4.6
Ali M. Ali,Abdelrahman M. Hamed,Mahmoud A. Taher,Mohamed H. Abdallah,Mohamed Abdel-Motaleb,Zyta M. Ziora,Ahmed M. Omer
Developing a variety of safe and effective functioning wound dressings is a never-ending objective. Due to their exceptional antibacterial activity, biocompatibility, biodegradability, and healing-promoting properties, functionalized chitosan nanocomposites have attracted considerable attention in wound dressing applications. Herein, a novel bio-nanocomposite membrane with a variety of bio-characteristics was created through the incorporation of zinc oxide nanoparticles (ZnONPs) into amine-functionalized chitosan membrane (Am-CS). The developed ZnO@Am-CS bio-nanocomposite membrane was characterized by various analysis tools. Compared to pristine Am-CS, the developed ZnO@Am-CS membrane revealed higher water uptake and adequate mechanical properties. Moreover, increasing the ZnONP content from 0.025 to 0.1% had a positive impact on antibacterial activity against Gram-positive and Gram-negative bacteria. A maximum inhibition of 89.4% was recorded againstEscherichia coli, with a maximum inhibition zone of 38 ± 0.17 mm, and was achieved by the ZnO (0.1%)@Am-CS membrane compared to 72.5% and 28 ± 0.23 mm achieved by the native Am-CS membrane. Furthermore, the bio-nanocomposite membrane demonstrated acceptable antioxidant activity, with a maximum radical scavenging value of 46%. In addition, the bio-nanocomposite membrane showed better biocompatibility and reliable biodegradability, while the cytotoxicity assessment emphasized its safety towards normal cells, with the cell viability reaching 95.7%, suggesting its potential use for advanced wound dressing applications.Keywords:aminated chitosan;ZnO nanoparticles;antibacterial activity;antioxidant activity;biodegradable membrane
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PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Bao-hui Chen,Bo-wen Wang,Peng-zhao Gao,Pei Zhang,Hui-hui Chen
In this paper, the effect of the raw particle size and the annealing process on the compositions, microstructure, mechanical, thermal, and electrical properties of ZnO varistors was investigated using X-ray diffraction, infrared, X-ray photoelectron spectroscopy, scanning electron microscopy, electric field–current density, capacitance–voltage, mechanical, and thermal expansion measurements. Furthermore, the ZnO grain growth mechanism during the annealing process was discussed in detail. Results show that when the raw particle size equaled 90 nm and sintering was performed at 1100 °C for 2 h, the obtained ZnO-based varistors possessed excellent mechanical, thermal, and electrical properties; the E 1mA , α, J L , and K values were 1015.3 V mm –1 , 37.98, 2.45 μA cm –2 , and 1.37, respectively, due to the highest bulk density and the finest uniform particle size distribution . When annealing occurred at 300 °C for three times, values of σ f , K IC , E 1mA , α, J L , and K reached 175.35 MPa, 1.96 MPa m 1/2 , 1180.2 V mm –1 , 43.58, 2.15 μA cm –2 , and 1.2, indicating improvements of approximately 14.7%, 4%, 16.2%, 14.7%, − 12.2%, and 11.11% compared with those of the non-annealed ZnO-based varistors, respectively, being due to the improved uniformity of grain size distribution and the re-distribution of donor Al 3+ and Y 3+ in the ZnO crystal and grain boundary. The annealing process lead to the transformation of Sb 3+ to Sb 5+ in the ZnO crystal, which could generate two additional coordination sites. The newly generated sites could combine with O 2- in other crystals to increase the grain growth, resulting in clear grain growth on the surface, improved grain size distribution, and regular grain shape in the interior of ZnO-based varistors.
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SYNTHETIC METALS
·
2021
·
IF 3.266
Zixiong Liu,Rong Hu,Junsheng Yu,Ruilin Wang,Jiang Cheng,Ming-ming Huo,Taiqi Wu,Lu Li
To improve the morphology and charge transport property of zinc oxide (ZnO) interface layer in the field of organic solar cells (OSCs), a novel ZnO sol-gel precursor was developed by redox reaction among zinc powder (Zn), hydrogen peroxide (H 2 O 2 ), and ammonia (NH 3 ·H 2 O) in aqueous solvent. This aqueous ZnO sol-gel precursor has advantages in cost and stability. Furthermore, photoelectric conversion performance of OSCs with ZnO layer (aqueous) is better than that of device with ZnO layer (nonaqueous). To further elaborate the relevance between the ZnO interface layer and the device performance, optical and morphology characteristics of precursor solutions, ZnO layers, and active layers were studied. Meanwhile, electrical characteristics of the OSCs were also analyzed. The results show less anion and larger colloidal particle size in aqueous sol-gel solution, which making the ZnO interface layer have fewer defects and larger surface roughness than nonaqueous-phase prepared ZnO layer. Thus, free electron could transfer from the active layer to ZnO layer more easily, and charge recombination is reduced at the interface. Moreover, the electron mobility of OSCs is also enhanced by the aqueous-phase prepared ZnO layer. Therefore, short-circuit current and photoelectric conversion performance of device are promoted.
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Catalysts
·
2021
·Vol. 11
·期 5
·535
·
IF 4.146
Shuaikang Zhu,Xiaona Ren,Xiaoxue Li,Xiaopo Niu,Miao Wang,Shuang Xu,Zheyuan Wang,Yunxi Han,Qingfa Wang
The copper-based catalyst is considered to be the only catalyst for electrochemical carbon dioxide reduction to produce a variety of hydrocarbons, but its low selectivity and low current density to C2products restrict its development. Herein, a core-shell xZnO@yCu2O catalysts for electrochemical CO2reduction was fabricated via a two-step route. The high selectivity of C2products of 49.8% on ZnO@4Cu2O (ethylene 33.5%, ethanol 16.3%) with an excellent total current density of 140.1 mA cm−2was achieved over this core-shell structure catalyst in a flow cell, in which the C2selectivity was twice that of Cu2O. The high electrochemical activity for ECR to C2products was attributed to the synergetic effects of the ZnO core and Cu2O shell, which not only enhanced the selectivity of the coordinating electron, improved the HER overpotential, and fastened the electron transfer, but also promoted the multielectron involved kinetics for ethylene and ethanol production. This work provides some new insights into the design of highly efficient Cu-based electrocatalysts for enhancing the selectivity of electrochemical CO2reduction to produce high-value C2products.Keywords:CO2electrochemical reduction;core-shell structure;ZnO@Cu2O;synergy effect;C2products selectivity
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2021
·Vol. 37
·期 3
·565-570
·
IF 1.307
Jian Shaoju,Tian Zhiwei,Zhang Kaiyin,Duan Gaigai,Yang Weisen,Jiang Shaohua
C e/ZnO decorated carbon nanofibers(CNFs) heteroarchitectures(Ce/ZnO/CNFs) have been synthesized using electrospinning technique followed hydrothermal method, which have a high visible light photocatalytic activity. The samples were characterized by means of SEM, FTIR and XRD. The photocatalytic performance of Ce/ZnO/CNFs was tested with the methylene blue in the presence of visible light irradiation. In this work, we have analyzed the effects of Ce doping amount, initial methylene blue(MB) concentration and dosage of Ce/ZnO/CNFs on photocatalytic efficiency of the composite. The results showed that the photocatalyst containing 1.0% Ce in molarity(CZC1) obtained by autoclaving at 150 °C has the best photocatalytic degradation of MB than other as-synthesized samples. Ce/ZnO/CNFs catalysts exhibit a good stability and reusability, which would be an economical and environmentally friendly photocatalyst for various practical applications.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Cheng Qian,Juanjuan Yin,Jianxun Zhao,Xuetong Li,Sufeng Wang,Zhenhua Bai,Tifeng Jiao
Water pollution is an urgent problem in the world today. The discharge of industrial wastewater such as organic dyes will cause serious pollution to water bodies, thereby affecting people's lives. Facing the increasingly severe water pollution problem, the demand for efficient dye degradation materials is also increasing. Artemia cyst shell (ACS), as a natural biological material, has a large number of microporous structures, so it can be used as a carrier for high-efficiency nanoscale catalytic materials. In this work, ACS-ZnO nanocomposites were successfully synthesized by a combination of high-temperature calcination and hydrothermal synthesis, and their properties and photocatalytic degradation properties for dyes were studied. Artemia cyst shells are calcined at high temperature to form an organic porous skeleton after pretreated. The structure is then loaded with ZnO nanoparticles to synthesize the target product through a hydrothermal reaction. Finally, the material is used to degrade methylene blue, Rhodamine B, and neutral red respectively under light irradiation. The results show that the photodegradation effect of ACS-ZnO nanocomposites with a certain ZnO content is significantly stronger than that of pure ZnO nanoparticles. At the same time, cyclic experiments show the high stability and sustainable use of this composite material.
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Micro & Nano Letters
·
2020
·Vol. 15
·期 15
·1126-1129
·
IF 0.975
Jun Wang,Aifeng Ning
Various sizes and morphologies of noble metal/zinc oxide hybrid materials have promising applications in surface-enhanced Raman scattering (SERS). Generally, organic agents used during the synthesis of metal nanoparticles will inexorably induce organic pollution on the surface of SERS substrate, resulting in a negative effect on detection sensitivity. Herein, a stable and clean 3D flower-like ZnO/Ag hierarchical microstructure SERS substrate was designed and fabricated via a simple photocatalytic method. This synthetic strategy does not involve usage of any organic agents, which ensures the cleanness and free of impurities interferences. As anticipated, the as-fabricated 3D flower-like ZnO/Ag SERS substrates with high surface-to-volume ratio increased numerous hot spots, and exhibited excellent detection sensitivity to Rhodamine 6G. A linear relationship between the Raman intensity and the concentration of Rhodamine 6G ranging from 10 −11 to 10 −4 M was realised. This work demonstrated a performance-enhanced SERS sensor based on microflower-like ZnO@Ag hybrids, which provides a potential method to develop highly sensitive and stable SERS sensor for organic molecules detection.
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