Arabian Journal of Chemistry
·
2022
·
IF 6.212
Shuyun Guo,Lingling Zheng,Wenjing He,Chaofan Chai,Xianghui Chen,Shaofang Ma,Ning Wang,Martin M.F. Choi,Wei Bian
A novel nanoprobe based on S,O-doped carbon nitride quantum dots (S,O-CNQDs) was designed and synthesized. The as-prepared S,O-CNQDs exhibits good biocompatibility and strong fluorescence at excitation 360 nm. It is found that folic acid (FA) could efficiently quench the fluorescence of S,O-CNQDs. The obtained S,O-CNQDs is capable of acting as a sensitive and selective probe for FA detection in the range 5.0–83.3 μM with a detection limit of 90 nM. The as-prepared probe has been successfully utilized for the detection of FA in various real samples with satisfactory recoveries (98.8–107 %) and small relative standard deviation (<5%). The reaction mechanism between S,O-CNQDs and FA has been discussed. In addition, FA-S,O-CNQDs formed through a classical cross-linking reaction between FA and S,O-CNQDs easily accesses and penetrates into HepG2 cells with high folate receptors expression. FA-S,O-CNQDs with low cytotoxicity and good biocompatibility shows great potential in FA detection and targeted imaging of cancer cells.
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Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 44
·9258-9265
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IF 7.571
Chenglong Dong,Mengfan Lu,Hailong Fan,Zhaoxia Jin
Developing advanced soft machines and tissue engineering for load-bearing cartilage or tendons requires tough hydrogels. However, the construction of double or triple crosslinked networks for these tough hydrogels, i.e., a strong network crosslinked by covalent bonds and one or two sacrificial networks built by hydrogen bonds or coordinate bonds, generally asks for multiple steps. It remains a challenge to develop hydrogels with a combination of excellent toughness and a high content of water through the time-saving one-pot process. This study demonstrates that this puzzle could be solved through engineering zirconium(IV)–amide coordinate bonds. To be specific, the combination of strong Zr(IV)–O and moderate Zr(IV)–N coordinate bonds in Zr-polyacrylamide (Zr-PAAm) hydrogels has the advantage that they are usually generated through multiple cross-linked networks. Compared to chemical crosslinked PAAm hydrogels, the highly transparent Zr-PAAm hydrogels crosslinked by Zr(NO3)4 displayed a 26-times increase in fracture stress, 4-times in fracture strain, 6-times in elastic modulus, and over 250-times in toughness. Besides, the mechanical properties of Zr-PAAm hydrogels could be altered over a wide range via changing the anion species, showing a dependence on the Hofmeister effect. The co-existence of Zr(IV)–N and Zr(IV)–O has been confirmed through XPS and FTIR characterizations. In particular, the effect of Zr(IV)–N in Zr–PAAm hydrogels has been verified by comparing the property changes of Zr-PAAm hydrogels before and after swelling in water, in which the Zr(IV)–N in the as-prepared hydrogels was replaced by Zr(IV)–O in the swollen gels. With ultra-stretchability and high transparency, the colorless Zr-PAAm hydrogels displayed rich interference colors under stretching, which brought great potential in anti-counterfeiting materials.
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高影响因子
Catalysis Science & Technology
·
2023
·Vol. 13
·期 6
·1748-1754
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IF 5
Shaoyuan Guo,Xinli Tong,Lingwu Meng,Guobao Yang
Selective oxidative C–C and C–O bond cleavage is of significance to the efficient utilization of biomass and biomass-derived platform compounds. In this work, the selective oxidative cleavage of C–C and C–O bonds has been developed with an iron-based catalyst (Fe–N–C) in the presence of molecular oxygen. Specifically, the β-O-4 lignin model compound was successfully converted to phenol and methyl benzoate in a methanol solvent, where the substrate conversion was 95.0% and the yields of phenol and methyl benzoate were 94.9% and 63.7%, respectively, when the reaction was performed with the Fe–N–C-850 catalyst at 120 °C for 4 h. Also, the oxidative transformations of other lignin models to phenols and methyl benzoates were achieved. Further investigations showed that the existence of the Fe3C phase in the catalyst plays an important role in the aerobic oxidative cleavage of C–C and C–O bonds in the β-O-4 lignin model.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2022
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IF 6.371
Xiaofei Fu,Junwu Tao,Zuming He,Yong Gao,Yongmei Xia,Zizhou Zhao
High-efficiency interfacial charge transfer is the key to achieve better spatial carrier separation, and thus to develop advanced heterogeneous photocatalysts for environmental remediation. However, It still remains a great challenge to design and exploit the effective charge transfer scheme. Herein, a novel Z-scheme In 2 S 3 /BiOBr with S−O covalent bonding was prepared by hydrothermal and subsequent thermal annealing methods. The obtained photocatalysts were systematically characterized and used for tetracycline hydrochloride degradation and Cr(VI) reduction in aqueous solution. As a result, the optimized In 2 S 3 /BiOBr heterostructure (IS/BOB-39) exhibited superior photocatalytic activities for tetracycline hydrochloride degradation and Cr(VI) reduction under simulated solar light irradiation compared with individual materials. The Z-scheme transfer mechanism was corroborated by trapping experiments, ESR and XPS analysis , which provided an effective transfer pathway for spatial separation of carriers. Moreover, the formation of chemical S−O bond between In 2 S 3 and BiOBr, which acted as a specific bridge to expediently transmit interfacial electrons, showed a synergistic effect with Z-scheme transfer model on the significantly enhanced photocatalytic performance. In addition, the In 2 S 3 /BiOBr heterojunction presented excellent cycle stability, resulting from the tight heterointerface. This work provides a promising approach to design and fabricate high effect Z-scheme heterojunction in wastewater treatment.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2022
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IF 4.598
Mingzhu Cui,Zhiqiang Xie,Meiling Wang,Xianming Zhang
Development of a high-performance electrode materials for the simultaneous sensing of ascorbic acid (AA), dopamine (DA) and uric acid (UA) is critical in clinical diagnostics. Novel polymer hydrogel-derived porous carbon has been investigated in sensing due to their high conductivity, hierarchical porous structure and environmental benignity. However, the high cost and cumbersome synthesis of the crosslinker for polymer hydrogel precursors make carbon production by pyrolysis greatly compromised. To address this challenge, here, a facile approach to N, O, S co-doped three-dimensional porous carbon frameworks (N, O, S-HCF) derived from methyl orange (MO) crosslinked polypyrrole hydrogel is developed. Experimental and spectroscopy demonstrate that the derived 3D porous structure and heteroatom doping effect create multidimensional electron transfer pathways and electrocatalytic activity centers. Specifically, the sensor exhibits potent and persistent electrochemical behavior with well-separated oxidation peaks and enhanced oxidation peak currents towards ascorbic acid (AA), dopamine (DA) and uric acid (UA). As a result, the N, O, S-HCF contributes to the effective determination of the three analytes in their mixture and the calibration curves show linear range of 2.5 × 10 −6 –1.0 × 10 −2 M, 1.8 × 10 −7 –8.7 × 10 −5 M, and 2.5 × 10 −7 –1.0 × 10 −4 M with detection limits of 1.0 × 10 −6 , 1.2 × 10 −7 , and 1.8 × 10 −7 M for AA, DA and UA, respectively. This study provides a simple strategy to build heteroatom doped porous carbon for the simultaneous monitoring of multiple electroactive species.
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Foods
·
2022
·Vol. 11
·期 6
·882
·
IF 5.561
Liangqin Xie,Zeyuan Deng,Jie Zhang,Huanhuan Dong,Wei Wang,Banghuai Xing,Xiaoru Liu
Flavonoids are well known for their extensive health benefits. However, few studies compared the differences between flavonoid O-glycoside and C-glycoside. In this work, flavonoid O-glycoside (isoquercitrin), C-glycoside (orientin), and their aglycones (quercetin and luteolin) were chosen to compare their differences on antioxidant activities and metabolism during in vitro digestion and in vivo. In vitro digestion, the initial antioxidant activity of the two aglycones was very high; however, they both decreased more sharply than their glycosides in the intestinal phase. The glycosidic bond of flavonoid O-glycoside was broken in the gastric and intestinal stage, while the C-glycoside remained unchanged. In vivo, flavonoid O-glycoside in plasma was more elevated than C-glycoside on the antioxidant activity; however, flavonoid C-glycoside in urine was higher than O-glycoside. These results indicate that differences of flavonoid glycosides and their aglycones on antioxidant activity are closely related to their structural characteristics and metabolism in different samples. Aglycones possessed higher activity but unstable structures. On the contrary, the sugar substituents reduced the activity of flavonoids while improving their stability and helping to maintain antioxidant activities after digestion. Especially the C-glycoside was more stable because the stability of the C–C bond is higher than that of the C–O bond, which contributes to the difference between flavonoid O-glycoside and C-glycoside on the absorption and metabolism in vivo. This study provided a new perspective for comparing flavonoid O-glycoside, flavonoid C-glycoside, and their aglycones on their structure–activity relationship and metabolism.Keywords:flavonoid;O-glycoside;C-glycoside;aglycones;in vitro digestion;antioxidant activity
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INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
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2022
·Vol. 57
·期 8
·5268-5279
·
IF 3.612
Yuhang Xing,Ruyi Li,Lu Xue,Mianhong Chen,Xuli Lu,Zhihao Duan,Wei Zhou,Jihua Li
Summary Mangiferin (MGF) is a phenolic compound isolated from mango, but its poor solubility significantly limits its use. In this study, MGF was embedded into the inner aqueous phase of W 1 /O/W 2 emulsions. Firstly, the dissolution method of MGF was determined. MGF remained stable in solution with pH 13 at 30 min, and its solubility reached 10 mg mL −1 . When the pH of MGF solutions was adjusted from pH 13 to pH 6, MGF did not immediately crystallise, providing sufficient time to construct the MGF-loaded W 1 /O/W 2 emulsions. Subsequently, the MGF-loaded W 1 /O/W 2 emulsions were constructed using polyglycerol polyricinoleate (PGPR) and calcium caseinate (CAS). The formation and stability of the W 1 /O/W 2 emulsions were investigated. The MGF-loaded W 1 /O/W 2 emulsions stabilised with 1% PGPR and 1% – 3% CAS exhibited a low viscosity, limited loading capacity, and poor stability. Conversely, the MGF-loaded W 1 /O/W 2 emulsions stabilised by 3%PGPR–3%CAS exhibited optimal loading capacity (encapsulation efficiency = 95.31% and loading efficiency = 0.91%) and stability, which was attributed to the fact that high viscosity and gel state retarded the migration of inner aqueous phase. These results indicated that the W 1 /O/W 2 emulsions stabilised by PGPR and CAS may be a potential alternative for encapsulating mangiferin.
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Foods
·
2022
·Vol. 11
·期 18
·2720
·
IF 5.561
Yaping Dai,Xuli Lu,Ruyi Li,Yupo Cao,Wei Zhou,Jihua Li,Baodong Zheng
W/O/W emulsions can be used to encapsulate both hydrophobic and hydrophilic bioactive as nutritional products. However, studies on protein stabilized gel-like W/O/W emulsions have rarely been reported, compared to the liquid state multiple emulsions. The purpose of this study was to investigate the effect of different oil–water ratios on the stability of W/O/W emulgels fabricated with salt-soluble proteins (SSPs) ofSipunculus nudus. The physical stability, structural characteristics, rheological properties, and encapsulation stability of vitamin C and β-carotene of double emulgels were investigated. The addition of W/O primary emulsion was determined to be 10% after the characterization of the morphology of double emulsion. The results of microstructure and rheological properties showed that the stability of W/O/W emulgels increased with the increasing concentration of SSPs. Additionally, the encapsulation efficiency of vitamin C and β-carotene were more than 87%, and 99%, respectively, and still could maintain around 50% retention of the antioxidant capacity after storage for 28 days at 4 °C. The aforementioned findings demonstrate that stable W/O/W emulgels are a viable option for active ingredients with an improvement in shelf stability and protection of functional activity.Keywords:W/O/W emulgels;Sipunculus nudus;salt-soluble proteins;vitamin C;β-carotene;co-encapsulation
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高影响因子
JOURNAL OF FOOD ENGINEERING
·
2022
·
IF 6.203
Xiang Huang,Rui Tu,Hongbo Song,Kai Dong,Fang Geng,Lei Chen,Qun Huang,Yingmei Wu
Double emulsions have very promising application prospects in the pharmaceutical, cosmetic, and food industries. Nevertheless, its usage in the food industry is restricted mainly due to its immense stability problems. Here, W 1 /O/W 2 double emulsion was prepared by two-step emulsification method using ultrasonic emulsification technology. The physicochemical stability, rheological properties, thermal stability, and microstructure of the double emulsion were investigated. The results revealed that W 1 /O/W 2 double emulsion with optimum stability was prepared on the parameters that the ratio of W 1 (gelatin)/O primary emulsion to the external aqueous phase (gelatin-EGCG-high methoxyl pectin ternary complex) was 6:4, ultrasonic power was 80 W, ultrasonic time was 6 min, and ternary complex concentration was 0.75%. The double emulsion produced under these conditions had the smallest particle size (1143 nm) and the maximum absolute zeta potential value (39.17 ± 0.50 mV). The results of full-featured stability analyzer manifested that the emulsion system no longer underwent phase separation. Confocal laser scanning microscopy (CLSM) successfully observed a uniformly dispersed double emulsion. Furthermore, dynamic rheological properties demonstrated that the cohesive strength of W 1 /O/W 2 double emulsion was strength than that of W 1 /O primary emulsion. Differential scanning calorimetry (DSC) analysis suggested that both remained stable throughout the temperature change, while the W 1 /O/W 2 double emulsion was more thermally stable. Hence, the gelatin-EGCG-high methoxyl pectin ternary complex can act as an effective emulsion stabilizer to stabilize the W 1 /O/W 2 double emulsion.
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高影响因子
Green Energy & Environment
·
2022
·
IF 12.781
Yang Zhou,Qiang Zeng,Hongyan He,Kejia Wu,Fuqiao Liu,Xuehui Li
In order to better understand the specific substituent effects on the electrochemical oxidation process of β -O-4 bond, a series of methoxyphenyl type β -O-4 dimer model compounds with different localized methoxyl groups, including 2-(2-methoxyphenoxy)-1-phenylethanone, 2-(2-methoxyphenoxy)-1-phenylethanol, 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethanone, 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethanol, 2-(2,6-dimethoxyphenoxy)-1-(4-methoxyphenyl)ethanone, 2-(2,6-dimethoxyphenoxy)-1-(4-methoxyphenyl)ethanol have been selected and their electrochemical properties have been studied experimentally by cyclic voltammetry, and FT-IR spectroelectrochemistry. Combining with electrolysis products distribution analysis and density functional theory calculations, oxidation mechanisms of all six model dimers have been explored. In particular, a total effect from substituents of both para -methoxy (on the aryl ring closing to C α ) and C α -OH on the oxidation mechanisms has been clearly observed, showing a significant selectivity on the C α -C β bond cleavage induced by electrochemical oxidations.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 17
·9722
·
IF 6.208
Xinliang Ye,Zhi He,Yuming Liu,Xiaoying Liu,Rouye He,Ganhang Deng,Ziqing Peng,Jiayu Liu,Zicai Luo,Xiaoling He,Xiang Wang,Jing Wu,Xiaowei Huang,Jingying Zhang,Chong Wang
How to fabricate bone tissue engineering scaffolds with excellent antibacterial and bone regeneration ability has attracted increasing attention. Herein, we produced a hierarchical porous β-tricalcium phosphate (β-TCP)/poly(lactic-co-glycolic acid)-polycaprolactone composite bone tissue engineering scaffold containing tetracycline hydrochloride (TCH) through a micro-extrusion-based cryogenic 3D printing of Pickering emulsion inks, in which the hydrophobic silica (h-SiO2) nanoparticles were used as emulsifiers to stabilize composite Pickering emulsion inks. Hierarchically porous scaffolds with desirable antibacterial properties and bone-forming ability were obtained. Grid scaffolds with a macroscopic pore size of 250.03 ± 75.88 μm and a large number of secondary micropores with a diameter of 24.70 ± 15.56 μm can be fabricated through cryogenic 3D printing, followed by freeze-drying treatment, whereas the grid structure of scaffolds printed or dried at room temperature was discontinuous, and fewer micropores could be observed on the strut surface. Moreover, the impartment of β-TCP in scaffolds changed the shape and density of the micropores but endowed the scaffold with better osteoconductivity. Scaffolds loaded with TCH had excellent antibacterial properties and could effectively promote the adhesion, expansion, proliferation, and osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells afterward. The scaffolds loaded with TCH could realize the strategy to “kill bacteria first, then induce osteogenesis”. Such hierarchically porous scaffolds with abundant micropores, excellent antibacterial property, and improved bone-forming ability display great prospects in treating bone defects with infection.Keywords:bone tissue engineering;cryogenic 3D printing;Pickering emulsion;osteogenesis;antibacterial
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高影响因子
CARBOHYDRATE POLYMERS
·
2021
·
IF 9.381
Lin Pan,Tianyu Fu,Hao Cheng,Jianchen Mi,Qingsen Shang,Guangli Yu
Gloiopeltis furcata is an edible alga that has long been consumed in China. However, the bioactive polysaccharides from G. furcata have been largely unexplored. Here, we show for the first time that a sulfated polysaccharide from G. furcata (SAO) could improve the integrity of the colonic epithelial layer and protect against dextran sulfate sodium-induced intestinal mucosal damage. Mechanistically, SAO attenuated colonic mucosal damage by therapeutically remodeling the interactions between gut microbiota and mucin O -glycans. Specifically, SAO increased the proportions of complex long-chain mucin O -glycans in the epithelial layer with two terminal N -acetylneuraminic acid residues and promoted the growth of probiotic bacteria including Roseburia spp. and Muribaculaceae . Altogether, our study demonstrates a novel application of SAO for the treatment of inflammatory bowel disease-associated mucosal damage and forms the basis to understand the therapeutic effects of natural polysaccharides from the perspective of symbiotic interactions between host mucin O -glycome and gut microbiome .
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高影响因子
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