SURFACE & COATINGS TECHNOLOGY
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2021
·
IF 4.158
Lixuan Ren,Yanzhen Zhao,Liu Yang,Wenling Cao,Huifang Wang,Xiaojie Lian,Xianghua Gao,Baolong Niu,Wenfeng Li
The bacterial infection is one of the main reasons for the failure of implant surgery. In this paper, catechol functionalized chitosan (CSCT) was used as a reducing agent and stabilizer to synthesize CSCT-Ag NPs. The composite coating of titanium surface was then electrodeposited by a CSCT layer initially, followed by spin-coating of a CSCT/gelatin (G)/CSCT-Ag NPs layer. The results of XRD , UV–Vis, and TEM showed that the silver nanoparticles were successfully synthesized with uniform distribution, and the particle size was 4–22 nm. The cytotoxicity test results of CSCT-Ag NPs on A549 and EA.Hy926 cells showed when the concentration of CSCT-Ag NPs was less than 25 μg/mL, the survival rate of the two kinds of cells was greater than 80%. First electrodeposition and then spin-coating is feasible through the coating adhesion test and the adhesion level up to 5B. Compared with the pure Ti substrate, the corrosion resistance and hydrophilicity of the composite coating surface are significantly improved. The antibacterial rate of the composite coating against E. coli and S. aureus can reach 99% and 96%. In conclusion, CSCT-Ag NPs and the method of preparing coatings by electrodeposition and then spin-coating have good clinical application potential.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Xiaoyong Qiu,Jun Huang,Hui Wang,Yulu Qi,Jiwei Cui,Jingcheng Hao
Hypothesis Water contamination from heavy metal ions is a major global environmental concern. Adsorbents based on biomaterials have been demonstrated to possess remarkable removal efficiency for metal ions, but the adsorption model of biosorbents is not clear and much efforts should be devoted to study the adsorption behaviors and understand the adsorption mechanism. Experiments The multifunctional rhodamine-modified chitosan (RMC) hydrogel for Hg 2+ adsorption with fluorescent turn-ON properties was fabricated through grafting the rhodamine-modified poly (ethylene glycol) benzaldehyde (RM-PEG) onto the hydrogel network serving as the fluorescence/colorimetric sensing receptor. The adsorption behaviors and colorimetric sensing mechanism of RMC hydrogel towards Hg 2+ were investigated in detail. Findings RMC hydrogel can remove more than 96.5% of Hg 2+ from aqueous solution with significant fluorescence response and colorimetric change. The high adsorption selectivity and colorimetric sensing mechanism of RMC hydrogel towards Hg 2+ can be explained by the hard and soft acid/base (HSAB) theory. The O atom in hydroxyl and carbonyl groups together with the N atom in amine/imine groups of RMC hydrogel play a vital role in the adsorption of Hg 2+ , while the colorimetric response and fluorescence enhancement of the hydrogel after adsorption are attributed to the specific spiro-lactam structure of rhodamine moieties. The adsorption isotherms and kinetics were investigated and well described by Freundlich isotherm and pseudo-second-order kinetic model . Furthermore, RM-PEG showed low cytotoxicity towards mouse embryonic fibroblast cells and RMC hydrogel can be used as a fluorescent pH indicator from 4.2 to 7.4, demonstrating the potential applications of RMC hydrogel in biological diagnosis.
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高影响因子
Desalination and Water Treatment
·
2016
·
IF 1.272
Manfeng Li,Zhaomei Wang,Bingjie Li
A cellulose/chitosan hydrogel bead was prepared by extruding and regenerating the blends from ionic liquid 1-ethyl-3-methylimidazolium acetate ([Emim]Ac) in ethanol. FT-IR, scanning electron microscopy (SEM) and X-ray powder diffraction techniques were used to prove the successful blending of both natural polymers (cellulose and chitosan). Brunauer–Emmet–Teller surface area and pore diameter analysis showed that the beads were nanoporous with pores measuring from 10 to 20 nm. Batch adsorption experiments demonstrated that the bead had a maximum adsorption capacity of 40 mg/g for congo red (CR) dye removal from aqueous solutions, which was more efficient than the most reported natural biosorbents. The CR adsorption capacity at equilibrium was related to initial CR concentration, dosage of beads and pH values of the CR solution. When the initial concentration of CR was 30 mg/L, and the adsorbent dosage was 2.0 g/L, the equilibrium of adsorption was reached within 115 min with the removal rate of 89.6%. The Langmuir model represented the adsorption isotherm data and the experimental results followed a pseudo-second-order rate model, indicating that intraparticle diffusion dominated the adsorption process. The cellulose/chitosan hydrogel beads can be used as an efficient adsorbent for dye contaminant removal from wastewater.
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RSC Advances
·
2015
·Vol. 5
·期 47
·37640-37647
·
IF 3.84
Haiyue Gong,Yiming Li,Mutai Bao,Dong Lv,Zhining Wang
The effective emulsification of oil and retention of the stability of this emulsion in sea water is an important requirement for the remediation process following a marine oil spill. To identify alternate dispersants for emulsifying oil following a spill, we investigated oil-in-water emulsions stabilized by self-assembled complexes of a hydrophilic petroleum hydrocarbon degrading bacteria, Bacillus cereus S-1, with the linear polysaccharide chitosan. We found that the addition of chitosan improves the ability of hydrophilic Bacillus cereus S-1 to function as an effective emulsifier. The self-assembled complex of Bacillus cereus S-1 and chitosan is able to adsorb on the interface and stabilize oil-in-water emulsions for months. Confocal laser scanning microscope (CLSM) imagings and SEM results showed that the oil-in-water emulsions were stable against coalescence by formation of a thin film of bacteria–chitosan complex. Bacillus cereus S-1 associated with chitosan in the aqueous phase gave rise to a network, which was also responsible for the emulsion stability. The ability of this complex work in seawater was still very effective. In addition to stabilization, the addition of chitosan dramatically enhanced the oil degradation rate of Bacillus cereus S-1. Due to the sustainability and low environmental impact of chitosan and petroleum hydrocarbon degrading bacteria, this is an environmentally friendly and inexpensive way to treat marine oil spills.
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Polymer Chemistry
·
2022
·Vol. 13
·期 12
·1751-1762
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IF 5.364
Yan Wang,Yuyong Ai,Xiaolin Liu,Bowei Chen,Yong Zhang
Herein, a novel indole-modified cross-linked chitosan aerogel (IAA-CTSA) was fabricated by grafting 3-indoleacetic acid onto chitosan and adding glutaraldehyde as a crosslinking agent through a facile two-step one pot method. The uptake properties and mechanism of uranium (U(VI)) by the constructed IAA-CTSA were discussed. IAA-CTSA was discovered to be a powerful and effective adsorbing material for the capture of U(VI) at pH 6.5. Equilibrium was achieved within 6 h, and the adsorption process accorded well with the pseudo-second-order kinetic model, inferring the chemical adsorption was the rate controlling step. The maximum capture capacity for U(VI) reached 847.5 mg g−1 calculated from the Langmuir model at 289 K. The removal efficiency for U(VI) of IAA-CTSA was strongly pH-dependent but insensitive to ionic strength. Furthermore, the removal efficiency of IAA-CTSA for U(VI) was maintained above 80% after 4 successive cycles using HCl and NaOH as eluents. The practical potential was tested using simulated U(VI) wastewater and illustrated that the resulting IAA-CTSA could be a competitive candidate for the elimination of U(VI) in simulated water environments. FTIR and XPS results illustrated that complexation, electrostatic and cation–π interactions were involved in the capture of U(VI). Briefly, the IAA-CTSA possesses good application prospects for wastewater remediation.
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RSC Advances
·
2019
·Vol. 9
·期 11
·6287-6298
·
IF 3.049
Yuanfeng Wei,Jianjun Zhang,Yazhen Zheng,Yaxiang Gong,Meng Fu,Chengran Liu,Liang Xu,Changquan Calvin Sun,Yuan Gao,Shuai Qian
The present study aims to develop cubosomes with surface cross-linked chitosan for sustained drug delivery and enhanced oral bioavailability of vinpocetine (VPT). GMO based liquid cubosomes with VPT loading were prepared by the high pressure homogenization method. In order to enhance the anti-digestion effect, chitosan was cross-linked on cubosomes by the Schiff reaction, followed by solidification via spray drying. The obtained spray-dried cubosomes (chito-cubosomes) are spherical microspheres with nano-sized holes on the surface. After reconstitution, the particle size and zeta potential of chito-cubosomes were determined to be ∼250 nm and +35.9 mV, respectively. In comparison to unmodified liquid cubosomes, chito-cubosomes exhibited a significant anti-digestion effect with a typical sustained release profile. In comparison to a VPT suspension, liquid cubosomes showed a 2.5-fold higher Cmax and 3.0-fold higher AUC0–∞, while chito-cubosomes further enhanced bioavailability (5.0-fold) with prolonged MRT (2.2-fold) and delayed Tmax (2.8-fold). The results suggested that chito-cubosomes could be a promising drug carrier for enhancing oral absorption with sustained release behavior.
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PubMed
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
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2016
·Vol. 16
·期 2
·1871-1882
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IF 1.338
Shi Haowei,Yang Junya,Zhu Lizhong,Yang Yuxiang,Yuan Hongming,Yang Yubing,Liu Xiangnong
In this paper, the chain-like core–shell structure Fe3O4@SiO2@Chitosan composite nanoparticles were synthesized by a two-step coating and following crosslinking glutaraldehyde on chitosan shell. The composite particles showed nearly monodisperse
105 sized particles with a core diameter of 80 nm and chitosan shell thickness of 12 nm. The synthesis conditions of the product were studied, and the morphology and properties of the composite nanoparticles were characterized by IR, XRD, TEM, SEM, EDS and VSM. The adsorption properties of
Hg2+, Pb2+ or Cu2+ ions on Fe3O4, Fe3 O4@SiO2 and the composite particles were in detail studied using the colorimetric method based on forming colored mercuric dithizone, rhodamine-Pb2+ complex and DDTC-Cu(2+)
complex. The results showed, adsorption isotherm, kinetics and separation coefficient of heavy metal ions on these three magnetic nanoparticles were concerned with pH, metal ions’ electronic configuration, silica coating and chitosan shell respectively. In addition, the recycle efficiency
was also studied. The findings demonstrated that Fe3O4@SiO2@Chitosan composite nanoparticles have great application value in the adsorption and separation of heavy metal ions.
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高影响因子
KINETICS AND CATALYSIS
·
2020
·Vol. 61
·期 3
·480-485
·
IF 0.934
Zhong S.
Abstract Nanofibers are attractive supporting matrices for catalytically active metallic catalysts. Herein, palladium species were successfully incorporated into the modified chitosan/poly(ethylene oxide)/maleic acid nanofibers by electrospinning. Then, the hybrid nanofibers were thermally cross-linked at elevated temperature to improve stable behavior in solution. X-ray diffraction and transmission electron microscopy characterizations show that the palladium nanoparticles are dispersed uniformly inside the hybrid nanofibers. This novel hybrid nanofiber mat displayed high catalytic activity for the Sonogashira coupling reaction of phenyl acetylene with aromatic iodides under copper free condition with moderate to excellent yields. Moreover, this nanofiber mat could be reused 10 times with little activity loss. Thus, we have proposed a facile way to prepare highly active and stable heterogeneous palladium catalyst.
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2022
·Vol. 29
·期 10
·1-17
·
IF 3.061
Shikhani Amani,Karam Sami,Said Majd,Atassi Yomen,Sarhan Hala
In this work, a hemostatic hydrogel is synthesized from biodegradable and biocompatible natural resources, namely chitosan and lactic acid. Without harsh chemicals as catalysts, the graft polymerization of lactic acid onto the chitosan backbone is carried out utilizing a domestic microwave to stimulate the grafting reaction, and create a physically cross-linked hydrogel. Structural characterization of the prepared hydrogel is performed using Fourier transformation infrared spectroscopy (FTIR) and X-ray diffraction (XRD), whereas morphological changes are determined using scanning electron microscopy (SEM). In vitro and in vivo tests are conducted to investigate the hemostatic performance of the hydrogel. The results of In vitro results reveal the effectiveness of the hydrogel in hemostasis, where it exhibits a significant low value of blood coagulation index (3.3%), a remarkable decrease in blood clotting time (110 s), and a good ability to adsorb red blood cells (45.6%) in comparison with the control samples. Furthermore, the findings of blood coagulation index and erythrocytes adsorption tests are remarkably better than those of some commercially available hemostatic products (GelSpon and Gas Hydrophel bandage). In addition, the in vivo test on mice shows that the hydrogel reduces blood coagulation time (58 s) in comparison with the regular physiological conditions without using any hemostatic material (93 s).
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Polymers
·
2022
·Vol. 14
·期 11
·2286
·
IF 4.967
Meiyan Wu,Wangfang Deng,Yidong Zhang,Chao Chen,Zhexuan Liu,Pedram Fatehi,Bin Li
It is highly desirable to develop a safe, highly efficient, and biodegradable drug carrier with an enhanced drug transport efficiency. Cellulose nanofibrils (CNF) and chitosan (CS) composite hydrogels are promising candidate carriers with biological compatibility and non-cytotoxicity. Herein, the CNF/CS composite beads were prepared by dissolving cellulose and CS in LiBr molten salt hydrate and regenerating in ethanol. This preparation method is facile and efficient, and the obtained porous CNF/CS beads with the weight ratio of 8:2 exhibited a large specific surface area, uniform micro-nano-sized pores, strong mechanical property, and water absorption-resistance. Moreover, these beads as drug (tetracycline hydrochloride, TH) carriers showed a higher encapsulation efficiency (47.4%) at the TH concentration of 5 mg/mL in 24 h, and a higher drug loading rate (12.0%) than pure CNF and other CNF/CS beads prepared with different ratios. In addition, the TH releasing behavior of CNF/CS (8:2) beads fitted well into the zero-order, first-order, and Higuchi models under an acid condition, indicating that the drug release of these pH-sensitive beads was mainly affected by drug concentration under an acid condition. Therefore, these CNF/CS beads have great potential to be used as drug carriers for medical applications.Keywords:cellulose nanofibrils;chitosan;drug carrier;tetracycline hydrochloride;drug release
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
·
IF 6.953
Die Wang,Luminita Marin,Xinjian Cheng
The detection of heavy metals, such as Hg 2+ and Fe 3+ , is of great significance. In this work, fluorescent small-molecule BODIPY (BY-3) bearing C C group was synthesized firstly. And then, the chitosan-based polymer sensor CY-1 was synthesized through the spontaneous NH 2 /C≡C click reaction. The synthesized CY-1 can effectively bind and recognize Hg 2+ /Hg + by the –C=N groups formed in the click reaction. Moreover, the macromolecular sensors CS-1 and CS-2 were synthesized by incorporating another recognition sites to CY-1. These synthesized macromolecular sensors can not only recognize Hg 2+ /Hg + , but also effectively recognize Fe 3+ /Fe 2+ . All of them exhibited significant quenching effect, visible to the naked eye under UV irradiation. The detection limit of CY-1 for Hg 2+ was 1.51 × 10 −6 mol/L, and the detection limit of CS-2 for Fe 3+ was 2.30 × 10 −6 mol/L. The BODIPY-chitosan sensors synthesized in this work have the functions of removing heavy metal ions besides the identifying ability. The maximum adsorption capacity of 1 g chitosan to Hg 2+ was 108 mg as the best one. This article provides a new method to prepare macromolecular sensors for the detection and removal of heavy metal ions. As a useful natural polymer, chitosan's application scope was enlarged.
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高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2021
·Vol. 33
·期 3
·795-806
·
IF 3.665
Fangzhou Yang,Bihe Yuan,Yong Wang,Xianfeng Chen,Liancong Wang,Hongming Zhang
Using layer-by-layer self-assembly technology, an intelligent nano-coating was constructed on melamine foam (MF) by electrostatic interactions between chitosan (CS) molecules and graphene oxide (GO) nano-sheets. According to the principle that GO is quickly reduced to reduced GO under high temperature, a fast fire-warning network can be constructed. Due to the protective effect of nano-coating constructed on MF, the thermal stability and flame retardancy of melamine composite foams are improved. As the nano-coating self-assembly layer increases to 20, its flame-response time is only 3 s, and the continuous alarm time is as high as 1280 s. These indicate that the prepared GO-CS composite foam possesses excellent flame retardancy and super-fast fire response. This study provides a novel idea for the application of bio-based nano-coating in the fire early response and warning.
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