ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Dumei Ma,Yongqi Wang,Jiacheng Ye,Chao Xin,Chuan-Fan Ding,Yinghua Yan
Carbapenem resistance and hypervirulence represent two distinct evolutionary pathways in Klebsiella pneumoniae, posing significant challenges in clinical settings. Of particular concern are convergent strains that combine both traits, complicating timely diagnosis and treatment. Herein, we present a novel MOF-derived bimetallic nanocube hybrid nanosheet (denoted Pt-G@Cu5Zn8C@Au) designed to enhance laser desorption/ionization mass spectrometry (LDI-MS) in distinguishing convergent strains from other variants. The novel material, synthesized through the pyrolysis of pristine MOFs, features uniformly distributed Cu and Zn synergistic metal sites within the carbon matrix, addressing critical limitations of current nanomatrices for in situ extraction of metabolic fingerprints from microbial cells, such as limited sensitivity (e.g., amorphous silicon, TiO2, and metal nanoparticles) or relatively weak conductivity and stability (MOF-based materials). Utilizing this advanced matrix, the metabolic fingerprints of 248 K. pneumoniae isolates were rapidly extracted, identifying 23 top VIP-score peaks as potential biomarkers for differentiating convergent strains from their variants. Combined with machine learning, the prediction model achieved 100% accuracy in distinguishing convergent strains from carbapenem-sensitive isolates (CS_cKP) or hypervirulent isolates (hvKP) using the SVM model, while achieving 78.26% accuracy in differentiating them from carbapenem-resistant isolates (CR_cKP) with the KNN/NB models. These findings highlight the high accuracy and efficacy of our assay in distinguishing convergent strains from their variants.
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PubMed
高影响因子
Advanced Optical Materials
·
2025
·
IF 7.2
Shan-Ping Wang,Wen-Wen Dong,Pan-Pan Cao,Xue Tian,Dong-Dong Xu,Jun Zhao,Dong-Sheng Li,Qichun Zhang
Although dye-encapsulated metal-organic framework (dye@MOF) phosphors exhibit excellent advantages (e.g., high quantum yield (QY) and luminescence tunability) in white light emitting diodes (WLEDs) lighting, the considerable fluorescence quenching of these dye@MOF phosphors remains an unmet challenge due to their low thermal conductivity and strong thermal accumulation. In this research, a high QY dye@MOF phosphor (QY = 78.4%) is successfully prepared using the secondary growth method. Through in situ doping of hexagonal boron nitride (BN), a yellow phosphor dye@MOF/BN is synthesized to mitigate thermal quenching and improve phosphor stability in WLEDs. The WLEDs constructed with 450 nm blue LED chips exhibit a temperature reduction of 10.2 °C at a current of 10 mA after continuous operation for 8 hours, compared to those fabricated by pristine phosphor. The dye@MOF/BN based WLEDs maintain high performance with a luminous efficacy of 93.89 lm W −1 , color rendering index of 86.4, and QY of 64.4%, indicating that the proposed strategy effectively improves heat dissipation without compromising optical performance.
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高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Yaqi Yu,Dilong Hong,Zeyu Zhu,Chuanfeng Zhao,Yuliang Jiang
Tryptophan(Trp), an essential amino acid for the body, plays a crucial role in many physiological processes. Abnormal levels of tryptophan can be harmful to living organisms. Accurate real-time monitoring of its concentration is vital for maintaining health. Since the organism can only obtain tryptophan through external intake, the development of fluorescent probes for detecting tryptophan in various environments holds significant value. In this study, a Zr-MOF was synthesized using Zr 4+ as the metal node, 1,2,4,5-benzenetetracarboxylic acid (H₄BTEC) and 4-carboxyphenylboronic acid (CPB) as organic ligands via a simple one-pot synthesis method, named UiO-66-COOH-B(OH)₂ (UBB). Subsequently, by virtue of the abundant carboxyl groups, UBB was post-synthetically modified with Eu 3+ to form UiO-66-COOH-B(OH)₂ @Eu 3+ (UBBE). UBB and UBBE were investigated as fluorescent probes for the detection of the Trp. UBBE probe demonstrated a significantly lower detection limit than UBB probe as 0.026 μM and 0.79 μM, respectively. Additionally, the UBBE probe exhibits good selectivity, stability, and other advantages, allowing successful detection in fetal bovine serum and various food samples.
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PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Yiyuan Peng,Mengbiao Liang,Ting Chen,Mengdi Zhao,Zhixiang Xie,Chunxian Guo
All-inorganic perovskite nanocrystals (CsPbX 3 NCs, X = Cl, Br, I) have emerged as promising candidates for applications in light-emitting diodes (LEDs), solar cells, photodetectors, and backlight displays, owing to their exceptional optoelectronic properties, including high photoluminescence quantum yield (PLQY), long carrier lifetimes, and narrow emission bandwidths. However, the intrinsic ionic nature of these nanocrystals renders them highly susceptible to environmental degradation, limiting their practical applications. Herein, we report the synthesis of CsPbBr 3 @MOF-5 composites through a physical mixing method: room-temperature supersaturated recrystallization of CsPbBr 3 NCs, followed by encapsulation within a hierarchical porous zinc-based metal-organic framework (MOF-5). By incorporating poly(ethylene oxide)-block-poly(propyleneoxide)-block-poly(ethylene oxide) Pluronic (P123) and 1,3,5-trimethylbenzene (TMB) as structure-directing agents, the pore architecture of MOF-5 was tailored to exhibit hierarchical porosity (2-35 nm), significantly enhancing both the PLQY and stability of CsPbBr 3 NCs. The CsPbBr 3 @MOF-5 composites achieved a remarkable PLQY improvement from 22% to 56%, retained 55% of their initial PL intensity after 60 days of ambient storage, and maintained 65% of PL emission under thermal stress (298-498 K). In contrast, pristine CsPbBr 3 NCs experienced complete quenching under identical conditions. Additionally, the composite exhibited superior resistance to anion exchange when combined with CsPbBr x I 3-x NCs. A white LED (WLED) device fabricated using CsPbBr 3 @MOF-5 composite and K 2 SiF 6 :Mn 2+ (KSF) red phosphor exhibited a luminous efficiency of 20.71 lm/W, a correlated color temperature (CCT) of 5486 K, and a broad color gamut covering 133.3% of the National Television Standards Committee (NTSC) standard, underscoring its potential for advanced lighting and display technologies.
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Food Analytical Methods
·
2020
·Vol. 13
·期 6
·1346-1356
·
IF 2.667
Chen Zhipeng,He Zhaolin,Luo Xiaogang,Wu Fengshou,Tang Sheng,Zhang Juan
Covalent organic framework (COF) was decorated on the surface of magnetic metal organic framework (MOF) to yield novel MOF@COF hybrid magnetic nanospheres, which were employed as a magnetic adsorbent for extraction of sulfonamides (SAs) in food and environmental samples. The morphology and structure of the synthesized hybrid nanospheres were characterized by transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectra, and nitrogen physisorption. Conditions for magnetic solid phase extraction for SAs were optimized by using the MOF@COF hybrid magnetic adsorbent. By coupling with high-performance liquid chromatography, a facile and sensitive method was developed for the determination of six SAs, showing good linearity in the range of 10–2000 ng/mL with R 2 > 0.99, high sensitivity with LODs of 0.1–0.5 ng/mL, and high reproducibility with RSDs < 3.9%. The established method was also applied to the rapid and efficient extraction of SAs in real samples such as tap water, pork, chicken, and shrimp samples.
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Nano Research
·
2021
·Vol. 15
·期 4
·3195-3203
·
IF 8.897
Wang Yan,Gao Hexiang,Wu Wenjia,Zhou Zhuofan,Yang Zhiwei,Wang Jingtao,Zou Yecheng
Porous laminar membranes hold great promise to realize ultrafast ion transfer if efficient and stable transfer channels are constructed in vertical direction. Here, metal-organic framework (MOF) nanosheets bearing imidazole molecules in the pores were designed as building blocks to assemble free-standing MOF laminar membrane. Then, Nafion chains were threaded into the pores induced by electrostatic attraction from imidazole molecules by slowly filtering dilute Nafion solution. We demonstrate that the threaded Nafion chains lock adjacent MOF nanosheets, affording highly enhanced structural stability to the resultant laminar membrane with almost no water swelling. Significantly, abundant acid-base pairs are formed in the pores along Nafion chains, working as efficient, continuous conduction pathways in vertical direction. Proton conductivities as high as 110 and 46 mS·cm −1 are obtained by this membrane under 100% and 40% relative humidity (RH), respectively, which are two orders of magnitude higher than that of pristine MOF membrane. The conductivity under low humidity (40% RH) is even over 2 times higher than that of commercial Nafion membrane, generating the maximum power density of 1,100 mW·cm −2 in hydrogen fuel cell (vs. 291 mW·cm −2 of Nafion membrane). Besides, the influence of water state on proton transfer in confined space is investigated in detail.
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高影响因子
ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Cao Cui,Jingyun Wang,Zhenguo Luo,Jin Wang,Chunxia Li,Zhengquan Li
Cobalt hydroxide in α-form (α-Co(OH) 2 ) is an attractive electrocatalyst for oxygen evolution reaction (OER). Traditional preparation of α-Co(OH) 2 nanosheets often leads to a packing morphology after synthesis or post electrode fabrication, which severely limits the exposure of surface active sites. In this work, we report the synthesis of a self-supported 3D flower-like structure consisting of 2D α-Co(OH) 2 nanosheets through a metal-organic-framework (MOF)-mediated synthetic method. We found that the formation of MOF intermediates can produce dispersive α-Co(OH) 2 nanosheets with a stable 3D hierarchical structure which can effectively avoid the packing of individual nanosheets. The developed α-Co(OH) 2 nanosheets exhibit an obviously enhanced OER activity in comparison with the nanosheets prepared with traditional method. The prepared α-Co(OH) 2 nanosheets have been well characterized and their formation mechanism is proposed.
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高影响因子
Reaction Chemistry & Engineering
·
2020
·Vol. 5
·期 5
·886-895
·
IF 3.441
Xing-Gang Si,Yun-Peng Zhao,Qing-Lu Song,Jing-Pei Cao,Rui-Yu Wang,Xian-Yong Wei
A highly efficient Ni/N–C catalyst was synthesized by facile pyrolysis of a Ni-containing metal–organic framework (Ni-MOF), and its catalytic hydrogenolysis performance towards C–O bonds in lignin was evaluated in detail using diphenyl ether (DPE) as a model compound. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analyses show that the flower-like nanosheets of the Ni-MOF shrink, forming a loose and ordered spherical structure during pyrolysis. Under the optimal conditions, DPE was completely converted and the selectivity to monomers (benzene, cyclohexanol and cyclohexane) reached 99.1%. During the catalytic hydrogenolysis conversion (CHC) of DPE, the direct cleavage of the Caromatic–O bond affording benzene and phenol is the major reaction pathway, and a low H2 pressure is crucial to increase the monomer selectivity. Furthermore, Ni/N–C-450 shows high hydrogenolysis activity for other lignin-derived aryl ethers, such as benzyl phenyl ether, dibenzyl ether, dinaphthalene ether, benzyl 2-naphthyl ether and 3-methoxyphenol.
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高影响因子
MOLECULES
·
2025
·Vol. 30
·期 24
·
IF 4.6
Shuyue Pang,Lina Chen,Yangyuxin Liu,Xiuting Lu,Hongfei Liu,Yuting Shu,Helong Bai,Jing Wang,Dongfang Shi
Mancozeb (MCZ), a widely used fungicide in agricultural production, has been reported as an environmental endocrine disruptor, posing serious risks to ecosystems and human health. In this work, multivalent Co-MOF nanozymes (MVCM) with excellent oxidase-like activity were synthesized, which can promote the oxidation of 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) into a blue oxidative product (ABTS•+), with an obvious absorption peak at 415 nm. With the addition of MCZ, the ABTS•+was reduced to colorless ABTS through the REDOX reactions between MCZ and ABTS•+. Based on the unique reducing behavior of MCZ, a nanozyme-based colorimetric detection platform was proposed for the detection of MCZ, with a linear range of 3–27 μM and a detection limit (LOD) of 0.15 μM. Furthermore, the sensor was integrated with smartphones and test strips, establishing a portable smartphone-based platform for the real-time, on-site, and visual quantitative detection of MCZ. The detection concentration range was 15–90 μM, with LOD as low as 15 μM. The assay exhibited high adaptability in practical applications. In summary, this work provided a simple, accurate, and low-cost approach for visual determination of MCZ without complicated instruments and procedures.
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高影响因子
MATERIALS RESEARCH BULLETIN
·
2025
·
IF 5.7
Xiaopeng Miao,Fanshi Meng,Xinxin Xu,Jiahui Wang,Xinyu Wang,Jian Tian
CuNi alloy nanoparticles loaded on nitrogen-doped carbon nanotubes (CuNi@N-C) were synthesized by using a Cu-Ni binary metal MOF as the precursor and adding melamine as an additional nitrogen source through high-temperature pyrolysis. At -1.0 V vs. RHE, the Faraday efficiency (FE) of CO produced by CuNi@N-C reaches 95.5%, which is much higher than that of Cu@N-C(FE CO : 14.0%) and Ni@N-C(FE CO : 37.0%). In-situ infrared spectra shows that the excellent ECO 2 RR property of CuNi@N-C is attributed to the reconfiguration of the electronic structure of the binary alloy catalyst, which increases the adsorption energy for CO 2 and promotes the desorption of *CO. This study explores and expands new paths for the synthesis of alloy catalysts.
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高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Liyan Liu,Yufei Zhang,Siqi Liu,Zhongbao Han,Zhan Yu
Tetracycline (TC) residues are frequently detected in food products and pose potential risks to human health, thus driving the demand for rapid and reliable analytical methods. In this study, a terbium-based metal-organic framework (Tb-MOF) constructed from a boronic-acid–containing ligand, 3,5-dicarboxyphenylboronic acid (5-bop), was synthesized via a one-pot hydrothermal route and evaluated as a fluorescent probe for TC. Comprehensive structural and optical characterization confirmed the successful synthesis of the crystalline Tb-MOF and its characteristic strong green emission under UV excitation. Mechanistic studies indicated that the fluorescence quenching of Tb-MOF by TC originates from dynamic quenching processes including the inner filter effect (IFE) and photoinduced electron transfer (PET). The Tb-MOF probe exhibited a linear response to TC in the concentration range of 0 to 60 μmol/L, with a detection limit of 153 nmol/L. Furthermore, the Tb-MOF sensor was successfully applied to detect TC in real-world food samples including milk and beef, yielding satisfactory recovery and accuracy. This work provides an effective alternative strategy for the quantitative monitoring of TC in complex food substrates, highlighting its significant potential for enhancing food safety assurance.
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高影响因子
BIOMASS & BIOENERGY
·
2025
·
IF 5.8
Hongrui Guo,Chengjie Sun,Mo Qiu,Hejuan Wu,Zhihui Ma,Jirui Yang,Feng Shen
The catalytic oxidation of glucose to formic acid (FA) represents a crucial route for biomass valorization. Metal–organic framework (MOF)-derived carbon composites offer exceptional tunability for catalyst design. Herein, a series of carbon-regulated Mn x O y /C catalysts from Mn-MOF-74 precursors via controlled calcination atmospheres and temperatures, achieving satisfactory performance in glucose-to-FA conversion. Comprehensive characterization reveals that the carbon matrix plays a synergistic effect: dispersing Mn x O y nanoparticles to enhance substrate accessibility, and preventing Mn leaching to improve stability. The FA yield is determined by fine-tuning key parameters: the (Mn 2+ +Mn 3+ )/Mn valence ratio and Mn x O y particle size. Combined DFT and experimental analyses demonstrate that Mn valence states determine reaction kinetics: Mn 3 O 4 exhibits elevated glucose adsorption energy and reduced formic acid (FA) desorption energy, while MnO displays an opposing trend, rationalizing the activity differences. This work establishes a carbon-mediated synergy strategy for designing efficient Mn-based catalysts in biomass oxidation upgrading.
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