JOURNAL OF NATURAL PRODUCTS
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2014
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IF 3.947
Hongmin Wang,Ruonan Ning,Yu Shen,Zhenhua Chen,Jinlong Li,Rujun Zhang,Ying Leng,Weimin Zhao
Fourteen new 3,4-seco-cycloartane-type triterpenes, lithocarpic acids A–N (1–14), together with one known compound, coccinetane E (15), were identified from the cupules of Lithocarpus polystachyus. The structures of 1–14 were determined by spectroscopic data analysis and chemical methods, and the absolute configurations of 1 and 4 were defined unequivocally by X-ray crystallography using Cu Kα radiation. Compounds 1–15 are the first examples of 3,4-seco-cycloartane derivatives isolated from the genus Lithocarpus. Among them, compounds 1 and 2, 9 and 10, and 11 and 12 were found to be three pairs of C-24 epimers, while compounds 7 and 8 represent the first examples of 3,4-seco-norcycloartane-type triterpenes. Compound 1, as the major component of the plant extract, showed potent antibacterial activity against Micrococcus luteus and Bacillus subtilis, with MIC values of 3.1 and 6.3 μg/mL, respectively, as well as inhibitory activity against human and mouse 11β-hydroxysteroid dehydrogenase type 1, with IC50 values of 1.9 and 0.24 μM, respectively.
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Catalysts
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2023
·Vol. 13
·期 12
·1459
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IF 3.9
Ou Sha,Xifeng Lu,Pei Su
The electrochemical advanced oxidation process is a promising technology for tackling wastewater pollution, but it suffers from poor pH adaptability and slow catalytic kinetics in a neutral and alkaline environment in a homogeneous system, as well as fast release of metal ions in a heterogeneous system. Herein, a boron- and nitrogen-codoped carbon nanotube-encapsulated transition metal (M@BN-C, M–Co, Cu) cathode with a similar structure was synthesized to explore activity trends and mechanisms. Characteristics of Co@BN-C and Cu@BN-C cathodes were examined and compared with the previously synthesized Fe@BN-C bifunctional cathode. The activity of sulfamethazine (SMT) degradation by the Co@BN-C cathode was higher than both Fe@BN-C and Cu@BN-C at pH = 3 and pH = 7, respectively. However, the activity of Co@BN-C was also higher than that of Cu@BN-C and lower than that of Fe@BN-C at pH = 9. It was observed that•OH and1O2were the main reactive oxygen species (ROS) using Co@BN-C and Cu@BN-C cathodes. The Co@BN-C generated the highest•OH for efficient SMT degradation through abundant H2O2generation, exhibiting the highest catalytic activity compared with the Cu@BN-C cathode. Overall, SMT degradation on the Co@BN-C cathode demonstrated better catalytic performance in real wastewater. This study provided insights into the fundamental catalytic trends and mechanisms of ROS production via the M@BN-C cathode, thus contributing to the development of the M@BN-C cathode for catalytic organic pollutant degradation.Keywords:electrocatalysis;water treatment;bifunctional cathode;reactive oxygen species;mechanism
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APPLIED SURFACE SCIENCE
·
2023
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IF 6.7
Yubao Li,Hanke Li,Shuang Li,Ming Li,Ping He,Yao Xiao,Jiufu Chen,Yafen Zhou,Tongyan Ren
Photocatalytic water splitting for hydrogen evolution is viewed as a promising strategy to address the energy and environmental issues. In this study, a series of NiO/Zn 3 In 2 S 6 (NiO/ZIS 6 ) p-n heterojunction photocatalysts have been prepared by the facile ultrasonic assisted deposition method. The as-obtained samples were systematically characterized employing various testing techniques. The photocatalytic performance of the p-n photocatalysts were evaluated by photocatalytic hydrogen production and the effect of different mass ratios of NiO to ZIS 6 on photocatalytic hydrogen evolution performance was also explored. The results indicated that the 25% NiO/ZIS 6 sample demonstrates optimal photocatalytic hydrogen evolution activity with a hydrogen evoluton rate of 21.79 mmol g −1 h −1 , which is 7.65 times higher than that of ZIS 6 . The mechanism exploration proves that the formation of NiO/ZIS 6 p-n heterojunction effectively promotes the separation and migration of photoinduced electrons and holes. Meanwhile, the recombination of charge carriers was restrained observably. This work may shed light on the design and preparation of novel p-n heterojunction photocatalysts with efficient photocatalytic hydrogen evolution performance and high stability.
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Food & Function
·
2023
·
IF 6.1
Zouyan HE,Hanyue Zhu,Jianhui Liu,Erika Kwek,Ka Ying Ma,Zhen-Yu Chen
Trimethylamine-N-oxide (TMAO), originating from dietary trimethylamine-containing nutrients such as choline, has been recognized as a risk factor for atherosclerosis. Mangiferin is a bioactive xanthone initially extracted from mango (Mangifera indica). The present study aimed to investigate the effect of mangiferin on TMAO-induced atherogenesis in mice fed a high-choline diet. Female ApoE-/- mice were randomly divided into three groups and fed either a control diet, a high-choline diet with 1% free choline, or an experimental diet with 1% free choline plus 0.5% mangiferin for 15 weeks. Our results showed that a high-choline diet elevated plasma TMAO level, accelerated atherogenesis, promoted cholesterol accumulation, and reduced the generation of short-chain fatty acids (SCFAs) by gut microbes. Mangiferin alleviated inflammation, and lowered plasma total cholesterol level by facilitating the elimination of neutral and acidic sterols in feces, resulting in a 16.7-29.0% reduction in aortic atherosclerotic lesions. Notably, mangiferin could favorably remodel the composition of gut microbiota by fostering the growth of the beneficial taxa Akkermansia, Parabacteroides, and Bifidobacteriaceae, while reducing the relative abundance of the pathogenic genus Helicobacter. This modulation led to a decrease in plasma lipopolysaccharide level, enhanced production of total SCFAs by gut microbes, and reduced susceptibility to atherosclerosis. In conclusion, mangiferin exhibited its ability to alleviate TMAO-induced atherosclerosis through its anti-inflammatory, cholesterol-lowering, and gut microbial modulatory activities.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
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IF 8.6
Hai Liang,Jianjiang Wang,Wanting Wang,Yingli Wang,Xinzhong Deng,Zhishuang Xue,Yang Sun,Gaohong He,Xuehua Ruan
Developing efficient biochar (BC) adsorbent for pollution removal has been a long-term exploration. However, the negative charge surface of pristine BC seriously impedes the transfer of anionic dye through the pore of BC and results in low adsorption capacity. Herein, N-doping enriched porous MgO-modified biochar (MBC) was successfully prepared through a facile nitrate activation method for anionic acid fuchsin (AF) removal. The N-doped group of secondary amine in MBC changes the surface charge of BC and facilitate the AF adsorption onto MgO . The as-prepared MBC exhibited superior adsorption capacity of 328 mg⋅g −1 . The adsorption process was well aligned with the Freundlich and pseudo-second-order kinetics models indicating a hybrid physicochemical adsorption mechanism. Further mechanism investigation indicates that N-doped group, MgO and functional groups in biochar matrix primarily contribute to AF adsorption. The mechanism includes: electrostatic attraction, π-π interaction, hydrogen bonding and pore filling. This research provides an environmentally friendly nitrate activation strategy for BC, which overcomes the inherent defects of BC in negative charge surface and provides a facile way of biomass valorization for pollution removal from the aquatic environment.
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JOURNAL OF HAZARDOUS MATERIALS
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2021
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IF 10.588
Songlin Zhao,Fushan Chen,Xiandi Zhu,Weijun Liu,Chenlin Wu,Jie Zhang,Shibin Ren,Zhengzhong Yan,Wenli Cao,Qunfeng Zhang,Xiaonian Li
In this study, a novel hierarchically porous N–doped carbon (HPNC) material was successfully prepared by soft-templating method. The commercial triblock copolymer of Pluronic F127 and a polyazine derived from hydrazine hydrate & glyoxal were used as soft template and precursor, respectively. The obtained materials were fully characterized and tested as a sorbent for the removal of hydrophilic dyes of Methylene blue (MB), Basic Fuchsin (BF), Eosin Y (EY) and Rhodamine B (RB) from their aqueous effluents. According to the characterization results, the synthesized material of HPNC-1000 presented thick fibrous morphology with micron size in diameter, hierarchically porous structure with surface area of 1853 m 2 /g, pore volume of 1.59 cm 3 /g and nitrogen content of 4.5 wt%. Adsorption-desorption investigation reveals that synergistic effect of hydrophobic interaction and hydrogen-bonding formation of the dye molecules with the sorbent was most pronounced in the adsorptions. The maximum adsorption capacities for MB, BF, EY and RB reached 0.83, 0.92, 1.23 and 1.83 mmol g −1 , respectively. The adsorption processes well fitted by the pseudo first-order kinetic model and the Liu′s isotherm. The sorbent can be regenerated by above 90% of the initial adsorption efficiency after six regeneration cycles.
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JOURNAL OF CHROMATOGRAPHY A
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2021
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IF 4.759
Huimin Deng,Ying Wang,Jinbang Wang,Shanshan Liu,Yuan Ji,Ziyan Fan,Zhonghao Li,Fei Yang,Zhaoyang Bian,Gangling Tang
N′ -nitrosonornicotine (NNN) is one of the most prevalent and toxic tobacco-specific nitrosoamines. A chiral center at its 2′-position results in R and S enantiomers, the partial double bond character of the N N = O group also results in E and Z isomers, therefore, NNN can form a total of four absolute configurations ( E -( R )-NNN, E -( S )-NNN, Z -( R )-NNN, and Z -( S )-NNN). This study investigated the resolution of R/S enantiomers and E/Z isomers of NNN by supercritical fluid chromatography tandem mass spectrometry (SFC-MS/MS). The baseline separation of E / Z -( R,S )-NNN isomers/enantiomers was accomplished through the optimization of chiral columns and co-solvents. Due to the lack of single standard of E / Z isomers, only R -NNN (sum of E -( R )-NNN and Z -( R )-NNN) and S -NNN (sum of E -( S )-NNN and Z -( S )-NNN) were further examined. Through the comprehensive optimization of SFC-MS/MS conditions, R -NNN and S -NNN were separated with a run time of 5 min, the developed method was validated, and its applicability to the determination of NNN enantiomers in burley tobacco samples was demonstrated. This study could be applied to preparative separation of single enantiomer and/or isomer of NNN, and could provide potential benefits to biologic activity studies on these enantiomers and isomers.
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JOURNAL OF CHROMATOGRAPHY A
·
2021
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IF 4.759
Huikai Shao,Liang Lai,Dongsheng Xu,Jacques Crommen,Qiqin Wang,Zhengjin Jiang
In this study, to selectively enrich N -glycans from complex biological samples, a novel Zr(IV) modified adenosine triphosphate (Zr(IV)-ATP) functionalized monolith was prepared through a facile approach. Well-defined macroporous structure was observed in the ATP functionalized monolith, which allows rapid mass transfer under low backpressure and is beneficial for the enrichment of N-glycans. After being modified with Zr(IV), the resulting Zr(IV)-ATP functionalized monolith could selectively capture N -glycans through the specific interactions between the sulfonate groups of 1-aminopyrene-3,6,8-trisulfonic acid (APTS) labeled N -glycans and Zr(IV). An APTS labeled maltooligosaccharide ladder was used to optimize the enrichment conditions for APTS labeled N -glycans, and capillary electrophoresis (CE) coupled with laser-induced fluorescence (LIF) detector was employed to evaluate the enrichment efficiency. The results show that the APTS labeled maltooligosaccharides could be enriched under the selected conditions and the signal amplify factors of the maltooligosaccharides were between 7.4 and 19.5 with RSDs for reproducibility from 4.0% to 8.3% (n = 3). Finally, the proposed method was successfully used for the enrichment and detection of N -glycans released from Ribonuclease B.
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MICROCHEMICAL JOURNAL
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2021
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IF 4.821
Liya Zhou,Xitong Zhou,Congli Zhao,Yihang Liu,Yaoxuan Li,Li Ma,Ying He,Yanjun Jiang,Jing Gao
Molybdenum carbide (Mo 2 C) doping nitrogen nanoparticles (Mo 2 C/NCS) were synthesized by a facile and friendly method. Owing to the high surface area and structural tunability, Mo 2 C/NCS possesses the excellent electron conduction channels and exposes numerous active sites. Based on these characteristics, Mo 2 C/NCS was adopted to fabricate glassy carbon electrodes to construct acetylcholinesterase (AChE) biosensors for detecting organophosphorus pesticides (OPs). The prepared biosensors exhibited wide linear ranges from 1.0 × 10 −14 to 1.0 × 10 −6 M with the detection limit of 4.47 × 10 −15 M for malathion and 1.0 × 10 −13 to 1.0 × 10 −5 M with a limit of detection of 2.57 × 10 −14 M for methyl paraoxon. The AChE biosensor also displayed the outstanding stability and selectivity. The prepared AChE biosensor was also employed to detect OPs in cabbage and apple samples with high accuracies and satisfactory recoveries. Therefore, this study manifested a prominent transition metal carbides nanomaterial for biosensors in detecting OPs and provided a way for other enzyme-based biosensors.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Xueqing Guo,Yang Liu,Wenjuan Dong,Qin Hu,Yong Li,Shaomin Shuang,Chuan Dong,Lishuai Cai,Xiaojuan Gong
Azithromycin (AZM) 1 is one of the most widely used antibiotics. AZM abuse is easy to cause great harm to human body, so developing a rapid and sensitive method to detect AZM is of great importance. Herein, 3-aminothiophenol as only reaction precursor, nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs) 2 were fabricated by one-step hydrothermal carbonization method. All characteristics demonstrate that N,S-CQDs possess good water solubility, high fluorescence stability and low cytotoxicity. Without being disturbed by amino acids and drugs, the most interesting finding is that AZM can efficiently quench the fluorescence of N,S-CQDs by a synergistic effect of electrostatic interaction and static quenching. A fluorescent probe for the detection of AZM was constructed with high selectivity and good sensitivity, achieving two linear ranges of 2.5–32.3 μM and 37.2–110 μM and a limit of detection of 0.76 µM. The proposed fluorescent method was used for the detection of AZM in cells with fulfilling results. More importantly, the fluorescent probe was successfully used to the detection of AZM in tablets and human urine with recovery rate and relative standard deviations of 98.2–104.8% and 0.04–3.46%, respectively, which was confirmed by the standard method of HPLC-UV. This finding illustrates the usefulness and feasibility of N,S-CQDs as an effective fluorescent probe for the detection of AZM in tablets and human urine, which is helpful for supervising and guiding pharmacy.
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SOLID STATE SCIENCES
·
2021
·
IF 3.059
Lin Liu,Moying Li,Peng Jiang,Kunyang Cui,Yuqian Wang,Jianlei Kuang,Wenbin Cao
The solid solution of YIn 1- x Mn x O 3 shows intense blue colors as well as excellent properties. In this paper, N- and N/S- doped YIn 1- x Mn x O 3 samples are successfully prepared by the high-energy ball milling method with hexamethylenetetramine (C 6 H 12 N 4 ), urea (CH 4 N 2 O) and thiourea (CH 4 N 2 S). The X-ray diffraction patterns of samples with various anion doping all show single phase and the oxidation state of Mn are maintained as +3. In C 6 H 12 N 4 treated YIn 0.7 Mn 0.3 O 3 , N is in the interstitial site while in CH 4 N 2 O treated YIn 0.7 Mn 0.3 O 3 , N exists in both interstitial site and substitution site. In CH 4 N 2 S treated YIn 0.7 Mn 0.3 O 3 , both S and N are in the substitution site and interstitial site. Due to the anion doping by N and S, the optical properties of the samples are modified and analyzed.
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CHEMISTRY OF MATERIALS
·
2021
·
IF 9.811
Rong Wang,Qingfu Cai,Yunyang Zhu,Zhen Mi,Weijun Weng,Yicheng Liu,Jiaxun Wan,Jianhua Hu,Changchun Wang,Dong Yang,Jia Guo
Low-bandgap covalent organic frameworks (COFs) emerge as one of the most intriguing conjugated polymers for the development of electronic devices, while they often lack desirable electron affinity, thereby compromising the activity and stability in electrochemical transformation. Here, we report an n-type semiconducting two-dimensional (2D) COF, featuring a low bandgap (1.36 eV) and strong electron affinity (4.41 eV) as well as high crystallinity and porosity. The columnar stacking array of the benzobisthiadiazole moiety in 2D COFs plays a critical role in elevating electroactivity. It not only leads to the outstanding electrical conductivity and air stability upon reductive doping but also enables the boost of transformation kinetics for polysulfides on the separators of lithium–sulfur batteries causing a higher capacity and better cycling performance. The design strategy underpins the versatile development of electroactive COF materials with desirable electronic properties and promotes their applicability in energy storage and electronics.
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