EUROPEAN POLYMER JOURNAL
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2014
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IF 3.242
Ting-Ting Xu,Jun Zhu,Cong Yuan,Qian-Li Yang,Kun Cui,Chun-Hui Li,Liu-He Wei,Zhi Ma
A series of new polymethylene- b -poly(styrene- co -2-hydroxyethyl methacrylate) (PM- b -P(St- co -HEMA)) and polymethylene- b -poly(styrene- co -2-hydroxyethyl methacrylate- g -poly(ε-caprolactone)) (PM- b -P(St- co -HEMA- g -PCL)) copolymers were successfully synthesized via a strategy combined polyhomologation of ylides, reversible addition–fragmentation chain transfer (RAFT) polymerization and ring-opening polymerization (ROP). Firstly, a hydroxyl terminated polymethylene (PM-OH) was obtained via polyhomologation of ylides followed by oxidation. Then, PM-OH was transformed to a macromolecular chain transfer agent (PM-CTA). Subsequently, RAFT copolymerizations of styrene (St) and 2-hydroxyethyl methacrylate (HEMA) were performed using PM-CTA as chain transfer agent, targeting the well-defined PM- b -P(St- co -HEMA) copolymers with controllable molecular weight and narrow molecular weight distribution. Finally, the ring-opening polymerization of ε-caprolactone was carried out using PM- b -P(St- co -HEMA) copolymer as initiator to achieve PM- b -P(St- co -HEMA- g -PCL) copolymer. The molecular weight and chain structure of the obtained copolymers were characterized by gel permeation chromatography (GPC), proton nuclear magnetic resonance ( 1 H NMR) and Fourier Transform Infrared spectroscopy (FTIR). Moreover, the fabrication of highly ordered porous films using the amphiphilic PM- b -P(St- co -HEMA) copolymers via a static breath-figure process was investigated.
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Desalination and Water Treatment
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2024
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IF 1
Jian Wu,Dajun Ren,Shuqin Zhang,Wenting Liu,Xiaoqin Zhang,Xiangyi Gong
Organic pollutants in aqueous solutions may potentially be adsorbed on biochar. In this study, biochar was derived from the pyrolysis of chitosan at 800°C. The removal rate of 2,4-dichlorophenol (DCP) exceeded 80%. Investigations by Fourier transform infrared spectroscopy and Brunauer– Emmett–Teller indicated that the adsorption of organic pollutants on biochar tends to be a physical process. The optimized pH was 5. All three isotherm models involved (Freundlich, Koble–Corrigan, and Henry) could describe the adsorption process of 2,4-DCP well on chitosan-biochar, which was non-uniform surface adsorption in a diluted solution. The adsorption was an endothermic process. It took 40 min to reach the adsorption equilibrium, and kinetics of the Elovich equation and intraparticle diffusion (IPD) model indicated that the adsorption rate at the rapid adsorption stage was simultaneously controlled by surface diffusion and IPD and that at slow adsorption stage was controlled by surface diffusion. The ionic strengths suggested that electrostatic interaction was not the dominant mechanism during this process.
研究领域:
环境科学
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环境工程
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材料科学
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污染控制化学
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吸附技术
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MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Xiao-Liang Yuan,Shu-Chen Yu,Lu Xiao,Ting-Ting Qiu,Xiu-Juan Chen,Xi-Ru Wang,Fang-Qi Cao,Wen-Bin Liu
1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1 H -pyrrolo[2,3- b ]pyridine-3-carboxamide (5F-CUMYL-P7AICA) represents a novel class of synthetic cannabinoids (SCs), constituting one of the most rapidly evolving groups of new psychoactive substances (NPS) that have been widely abused in recent years. However, precise qualitative analysis and accurate quantification pose significant challenges due to the lack of reference materials (RM) available for forensic drug prohibition and sentencing judges. Consequently, RM or certified reference materials (CRM) are essential for ensuring exact measurements and traceability of results in chemical analyses. The pure 5F-CUMYL-P7AICA candidate was autonomously synthesized through a two-step reaction process and subsequently purified via two-column chromatography. Two quantitative analytical methods were employed during the assessment of the pure 5F-CUMYL-P7AICA: quantitative nuclear magnetic resonance spectroscopy of hydrogen ( 1 H qNMR) method and mass balance (MB) method. For the 1 H qNMR, the mass fraction value reached 99.86% which could be traced back to the internal standard (benzoic acid). For the MB methods, the mass fraction value was 99.90% while the structurally related impurities of the candidate (0.05%), inorganic impurities (0.000006%), water (0.05%), and volatile organic solvent (0, or not detected) have been subtracted. Finally, the certified value was assigned to 99.9%, with an expanded uncertainty of 0.3% ( k = 2). Furthermore, the application of CRM would be finished in our subsequent work, and we anticipate that this high-purity CRM could play an essential role in the field of forensic science and sentencing judgement.
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ANALYTICAL LETTERS
·
2022
·
IF 2.267
Lanying Xu,Yingying Huang,Bingshan Zhao,Limin Ren,Tao Long
β-Cyclodextrin modified magnetic microspheres were synthesized and used as an effective adsorbent for the solid-phase extraction of three phenols from water samples. Scanning electron microscopy and Fourier transform infrared spectrometry were used to characterize the adsorbents. The major parameters affecting the extraction and desorption efficiencies, such as adsorbent dosage, extraction time, pH, ionic strength, and eluent type were systematically optimized. Under these conditions, three phenols in water samples were extracted and determined by high performance liquid chromatography (HPLC) with diode array detection (DAD). Limits of detection (LODs) of 0.04–0.34 ng mL−1 and limits of quantification (LOQs) from 0.13 to 1.14 ng mL−1 were achieved with good repeatability (relative standard deviation <7.5%). The developed method was applied for the determination of 2,4-dichlorophenol, 2,4-dinitrophenol and bisphenol A in spiked Yangtze River water, and the recoveries were from 81.0% to 94.9%. The results demonstrated that the combination of magnetic solid-phase extraction (MSPE) with HPLC-DAD is suitable for the determination of trace phenolics in environmental water.
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APPLIED SURFACE SCIENCE
·
2026
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IF 6.6
Zihao Guo,Zeqi Liu,Chaoxuan Wang,Lei Qian
Here, oxygen vacancy was introduced into hexagonal β-Ni(OH) 2 (NV) nanosheets to prepare poly (vinylidene fluoride-co-hexafluoropropylene)-based dielectric composites. Oxygen vacancy gradients were controlled, and the enhanced effects on energy storage performance were systematically investigated. It was found that the oxygen vacancy elevated the Ni 2+ /Ni 3+ ratio, shifted the Fermi level downward and induced formation of deep trap states. The moderate oxygen vacancies produced uniformly distributed deep strap states, which delayed the carrier migration by the capture-release mechanism. The Fermi level (E v − E f ) of NV 1.5 was 1.064 eV and showed the smallest energy separation from the valence-band, resulting in the highest interfacial potential barrier and inhibiting the charge injection. So, the oxygen vacancy obviously affected leakage current, breakdown strength and energy density. It was observed that leakage current density of the composites reduced to 3.48 × 10 −8 A/cm 2 . At the 0.3 wt% loading of NV1.5, the composite achieved a breakdown strength of 792.97 kV/mm and an energy density of 21.15 J/cm 3 (88.17 % over the matrix), with charge–discharge efficiency of 74.12 % and below 1 % performance degradation after 10 4 cycles. This work establishes a novel route based on defect engineering for dielectric storage materials at the atomic level. Download: Download high-res image (101KB) Download: Download full-size image
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ENVIRONMENTAL RESEARCH
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2026
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IF 8.2
Fengling Jiang,Ziwei Lan,Yongzheng Ma,Yuan Zhang,Xiaoqing Li,Dickon H.L. Ng,Jia Li
Micro/nanomotors have demonstrated significant potential in environmental monitoring and water remediation owing to their enzyme-like catalytic properties and self-driven ability. Herein, we developed a conical Co(OH) 2 @MnO 2 micromotor through an integrated oil bath-hydrothermal synthesis strategy. The micromotors feature MnO 2 nanosheets arranged in a two-dimensional cross-array architecture on their microconical surfaces, which effectively catalyze H 2 O 2 decomposition to produce oxygen bubbles, enabling robust self-propulsion. The speed of the micromotor can reach 138.59 ± 2.03 μm/s in7 wt% H 2 O 2 solution. The combination of excellent enzyme-like activity and self-driven ability of micromotor constructs a dynamic sensitive detection platform for resveratrol (RES, 3,4′,5-trihydroxystilbene), a potential pollutant in water, with a low concentration detection limit of 0.23 μM. In addition, hydrogen peroxide and peroxymonosulfate (PMS) were used as catalytic substrates to catalyze the micromotor to generate various reactive oxygen species (ROS), thus achieving efficient synergistic degradation of resveratrol. Under neutral pH conditions, the degradation rate of resveratrol by the micromotors was 91.6% within 40 min. This study provides an intelligent strategy for developing dynamic sensors with the dual functions of detecting and degrading RES simultaneously.
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ACS Applied Nano Materials
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2026
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IF 5.8
Ying Li,Yaozu Jia,Lili Wu,Hong Gao,Jing Yao
Lithium–sulfur batteries (LSBs) have attracted significant attention due to their high energy density and low cost. However, further progress in this technology is severely hindered by the shuttle effect of lithium polysulfides (LiPSs) and the sluggish redox kinetics of sulfur cathodes. To overcome these challenges, the application of nanocatalysts into the separators of LSBs boosts the LiPS conversion efficiency. In this study, MoOx (2 < x < 3) submicrometer rods with different oxidation levels are fabricated through precise temperature and atmosphere process parameters. The results show that the composite crystal structure material combines the high electrical conductivity of MoO2 with the high catalytic activity of MoO3, and when used to modify the polypropylene separator, it exhibits catalytic activity for the sulfur reduction reaction and the sulfur evolution reaction. The LSBs deliver a discharge specific capacity of 632.8 mAh g–1 at 8 C and maintain stable cycling for 700 cycles at 1 C, with 0.056% capacity decay per cycle. This study provides a pathway for the preparation of bifunctional catalysis with an integrated structure for LSBs.
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JOURNAL OF FLUORESCENCE
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2025
·Vol. 36
·期 2
·1445-1456
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IF 3.1
Huang Weihui,Tang Jidong,Ma Wenjin,Tao Xiaoqi
Structure-switching aptamers (SSAs) generate measurable signals through target-induced conformational changes, serving as sensitive molecular recognition elements. We developed a dual-fluorescence SSA for ochratoxin A (OTA) detection by inserting 2-aminopurine (2AP) into the OTA aptamer and hybridizing a complementary DNA (cDNA) strand at the 5’ end. OTA binding induced the aptamer-cDNA duplex to form a G4, enhancing 2AP fluorescence at 370 nm. Together with the intrinsic fluorescence of OTA at 450 nm, this enabled ratiometric dual-fluorescence measurements without external quenchers or fluorophores. To elucidate the molecular mechanism, all-atom molecular dynamics (MD) simulations and spectroscopic experiments assessed the effects of cDNA hybridization sites and strand lengths on sensing performance. Simulations further examined OTA binding at various 2AP insertion sites. Apt@2AP-cDNA1, with cDNA hybridized to bases 1–12, exhibited a binding pattern closely resembling the original aptamer. Umbrella sampling simulations revealed similar binding affinities: 46.3 kJ/mol for Apt@2AP-cDNA1 and 43.2 kJ/mol for the original aptamer. Experimentally, Apt@2AP-cDNA1 converted to G-quadruplexes more efficiently than other designs. A ratiometric dual-fluorescence aptasensor using Apt@2AP-cDNA1 was developed, with a linear detection range of 10–800 nM, a detection limit of 5.9 nM. The dual-fluorescence ratiometric aptasensor has good selectivity and was proven effective for detecting OTA in beer samples.
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Cell Reports
·
2026
·Vol. 45
·期 7
·
IF 7.7
Liwei Zheng,Minghui Li,Weilin Gu,Jing Zhao,Bei Jiang,Qianqian Jiang,Kun Liu,Yu Guo,Ran Xu,Xin Liu,Ting Zhang,Danli Yang,Sidi Yang,Lihong Liu,Qingquan Liu,Lin Wang,Sujun Zheng,Fengmin Lu,Xiangmei Chen
SARS-CoV-2 infection remains a global health threat, yet its pathogenic mechanisms are incompletely understood. Here, we show that viral nucleocapsid protein (NP) is detectable in the serum of patients with SARS-CoV-2 infection independently of viral RNA. Using virus-like particle (VLP) systems and in vitro infection models, we demonstrate that NP is secreted in a vesicle-free form via type I unconventional protein secretion (UPS) pathway. This process is regulated by NP phosphorylation and oligomerization, coordinated by viral structural proteins, and dependent on membrane components including heparan sulfate proteoglycans (HSPGs) and phosphatidylinositol 4,5-bisphosphate (PI (4,5) P 2 ). Secreted NP is preferentially taken up by granulocytes and induces the release of inflammatory cytokines, including IL-6 and TNF-α. Our findings shed a light on the secretion mechanism of this pro-inflammatory NP, highlighting it as a potential therapeutic target for COVID-related systemic inflammation.
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ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Yu Tian,Yifei Guan,Fang Yu,Jichao Li,Jian Liu,Shengqing Xia
While transition metal doping is widely adopted to optimize Mg3(Bi, Sb)2-based thermoelectrics, conventional high-concentration doping inevitably induces detrimental grain boundary segregation, creating a convoluted mixed effect that obscures the intrinsic regulatory roles of the dopants. To systematically unveil these fundamental impacts, we establish a low-concentration doping paradigm. By synergizing a precisely controlled low-concentration strategy with an optimized synthesis process, 3d transition metals (Mn, Fe, Co, Cu) are homogeneously incorporated into the bulk lattice without boundary enrichment. Based on this homogeneous microstructural framework, distinct doping effects are systematically revealed. Fe and Co act as highly efficient electron donors, elevating the carrier concentration to >1.5 × 1020 cm–3. In contrast, Mn fundamentally optimizes the carrier scattering mechanism via effective mass reduction, leading to a remarkable 2.6-fold enhancement in carrier mobility. Consequently, the lightly Mn-doped sample achieves an optimal balance, yielding a peak power factor of ∼30.7 μW/(K2cm) and a maximum zT of 1.03. Furthermore, this homogeneously doped sample demonstrates optimized macroscopic durability, retaining consistent electrical properties after 3-month ambient air exposure and withstanding 50 rigorous thermal shock cycles. Ultimately, this work clarifies how homogeneously incorporated dopants regulate transport properties and stabilize the crystal matrix, establishing precise low-concentration as a robust framework for high-performance and durable thermoelectrics.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Ting Xiao,Fozia Sultana,Xiaojing Liu,Yu Duan,Renkun Li,Kexin Sun,Tongtong Li,Renhong Li
Exploiting low-crystallinity as a structural feature offers a powerful route to unlock new catalytic functionalities by maximizing defect density, tuning electronic structures, and facilitating rapid charge transfer. Moreover, the disordered catalysts are prone to electrochemical reconstruction, generating highly active oxyhydroxide species, thus promoting the catalytic activity. Here, we first prepare a low-crystallinity Ni(OH) 2 /FeOOH heterojunction pre-catalyst directly grown on nickel foam via electrodeposition, followed by electrochemical reconstruction to synthesize the final electrocatalyst with surface-enriched Ni-Fe oxyhydroxide species (ER-Ni(OH) 2 /FeOOH). The defect-rich structure synergistically couples Ni and Fe species, enabling an exceptionally low overpotential of 241 mV at 100 mA cm −2 for the alkaline oxygen evolution reaction (OER), while maintaining stable operation for over 40 h. The density functional theory (DFT) calculations confirm that the low-crystallinity heterointerface tunes the electronic structure and lowers the energy barrier for the rate-determining (RDS) *OH→*O step, thus providing a theoretical basis for the observed enhancement in OER activity. This work underscores the potential of low-crystallinity interface engineering as a powerful approach for constructing next-generation OER catalysts.
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ACS Synthetic Biology
·
2026
·
IF 4.5
Junpeng Jia,Yifeng Wei,Yating Li,Jason Tan,Yiling Hu,Yang Tong,Xinan Jiao,Yan Zhang,Yan Zhou
2-amino-deoxyadenosine (dZ) occurs naturally in certain bacteriophage genomes, where it replaces deoxyadenosine, forming three hydrogen bonds with thymidine. This noncanonical deoxyribonucleoside underlies the unique biophysical properties of dZ-DNA. Its corresponding ribonucleoside has been introduced to RNA to form Z-modified RNA, with promising applications in vaccine production and biomedicine. Unlike dZ-DNA, Z-modified RNA has only been synthesized in vitro, which required the addition of chemically synthesized 2-amino-adenosine triphosphate (ZTP) as a precursor. Here, we describe enzyme engineering studies on dZMP–succinate-synthetase (PurZ), a key enzyme in the bacteriophage dZ-DNA biosynthetic pathway that natively catalyzes the conversion of deoxyguanosine monophosphate (dGMP) to dZMP–succinate. Through site-saturation mutagenesis, we generated mutants with altered substrate specificity, capable of catalyzing the conversion of GMP to ZMP–succinate. We further demonstrated that these mutants, in combination with bacterial adenylosuccinate lyase, guanylate kinase and nucleoside diphosphate kinase, efficiently convert GMP to ZTP, marking a critical step in developing a biosynthetic pathway for Z-modified RNA, and enabling enzymatic synthesis of ZTP on a semipreparative scale. Our work provides the basis for further research on the impacts of Z-modified RNA in living organisms, and supports the cost-effective production of Z-modified RNA vaccines and therapeutics.
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