ACS Nano
·
2026
·
IF 17.3
Zhen Fang,Jianbo Wu
Ultrafine high-entropy intermetallics (HEIs), which synergistically combine high-entropy effect, size effect, and ordered intermetallic structure, have attracted considerable attention as promising candidates for highly active and durable catalysts. However, the sluggish diffusion inherent to the complex multielement environment of high-entropy systems necessitates high temperatures to drive atomic ordering, which typically leads to severe nanoparticle sintering in the traditional thermal process. Here, we address this challenge via a multithermal-pulse control strategy that effectively suppresses long-range atomic diffusion-mediated interparticle sintering and intraparticle phase separation during short-range atomic ordering, enabling the synthesis of uniform sub-3 nm HEI nanoparticles. By varying the number of thermal pulses to precisely control the chemical ordering degree of PtFeCuCoNi alloy nanoparticles, we discover a clear positive correlation between the ordering degree and oxygen reduction performance. The HO-PtFeCuCoNi nanoparticles with the highest ordering degree exhibit the best catalytic activity (MA of 0.95 A mgPt–1 and SA of 1.18 mA cmPt–2) and stability (MA retention of 70.8%, SA retention of 70.4%, and ΔE1/2 of 6 mV) compared to their less ordered counterparts and commercial Pt/C. This multipulse strategy provides a feasible route to utilize pulse dynamics for capturing ordered structures and regulating the sintering-ordering trade-off and offers useful guidance for the structural design of multicomponent alloys.
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PubMed
高影响因子
Food Chemistry-X
·
2026
·
IF 9.2
Weiyi Xu,Yutong Meng,Fan Yu,Huanfeng Ye,Xuejiao Xu,Jie Chen,Xianrui Liang,Sheng Fang
This study evaluated Osmanthus fragrans fruit (OFF) peel as a potential source of anthocyanin-based natural colorants. Anthocyanins were extracted using acidified ethanol and purified by macroporous resin adsorption, yielding a pigment-rich extract with a recovery of 10.4 ± 0.2% from dried peel. HPLC–MS/MS analysis indicated that cyanidin-3-O-rutinoside (C3R) was the predominant anthocyanin in the extract. The molar absorptivity of C3R was experimentally determined to enable more accurate quantification of C3R-rich systems. The purified extract exhibited typical pH-dependent color behavior, maintaining a stable red coloration under acidic conditions (pH 2.0–4.0). Thermal stability experiments showed that C3R degradation was strongly influenced by temperature and pH, and the degradation behavior followed first-order kinetics. In addition, the extract displayed measurable antioxidant capacity in DPPH and FRAP assays. These results demonstrate that O. fragrans fruit peel is a promising source of C3R-rich anthocyanins with potential applications as natural colorants in acidic food systems.
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高影响因子
Reaction Kinetics Mechanisms and Catalysis
·
2025
·
IF 1.7
Guo Lirong,Yang Xiaodie,Shao Huijuan,Zhang Xuzhi,Wang Yating,Jiang Tao
We have investigated the effect of different impurities (CO, CO 2 , CS 2 , CH 3 OH, H 2 O, C 4 H 4 S) on the silicon-bridged diphosphine(PNSiP)/CrCl 3 (C 4 H 8 O) 3 /modified methylaluminoxane ethylene tri-/tetramerization system. The results showed that the addition of trace impurities has a certain inhibitory effect on catalytic activity. The influence of impurities on the catalytic activity of the catalyst system was as follows: CO > CO 2 > CS 2 > CH 3 OH > H 2 O > C 4 H 4 S. CO showed the most significant inhibitory effect in reducing activity from 1.75 × 10 6 g/(mol Cr h) to 0.74 × 10 6 g/(mol Cr h) at an addition of 0.2 ppm. Through the analysis of nuclear magnetic resonance (NMR) and ultraviolet–visible spectrophotometry (UV–vis), we found that carbon monoxide mainly inactivates the catalytic system by coordinating with chromium active sites, while methanol and water reduce the catalytic activity by destroying the structure of modified methylaluminoxane. Furthermore, we also proposed a possible reaction path between carbon monoxide and the chromium active center. Graphical abstract
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PLoS One
·
2025
·Vol. 20
·期 6
·e0324586
·
IF 2.6
Jie Yuan,Chongyong Gao,Wang Xin,Fanlin Meng,Hong Zhang
Background
Ulcerative colitis (UC) is a recurrent inflammatory condition of the bowel with a multifaceted pathogenesis, including programmed cell death, oxidative stress, and immune-mediated inflammation. As a recently identified type of cell death, disulfidptosis has an unclear role in UC.
Methods
We analyzed clusters of disulfidptosis-related genes (DRGs) and immune cell infiltration in 361 patients with UC from the GSE73661and GSE92415 datasets. Differentially expressed genes (DEGs) were identified using unsupervised clustering methods, and hub genes were selected using machine learning algorithms. Additionally, potential key components of potential traditional Chinese medicines for the treatment of UC were predicted based on hub genes. Finally, experimental validation was performed through qRT-PCR, western blotting, and immunohistochemistry.
Results
We identified two molecular clusters related to disulfidptosis, each showing significant heterogeneity in gene expression and immune profiles. Hub genes associated with disulfidptosis, CXCL1, HMGCS2, AQP8, and SLC26A2, were further screened and validated. Additionally, potential traditional Chinese medicines for UC were predicted. 3’-Methoxydaidzein (MHD), a key constituent of Puerariae Radix, inhibited LPS-induced inflammatory responses in Caco2 cells and alleviated DSS-induced colonic injury in UC mice via upregulation of SLC26A2.
Conclusion
DRGs demonstrate strong discriminatory power in distinguishing UC subtypes. Cluster with high expression of SLC26A2 showed a UC phenotype with a milder degree of damage. Additionally, we identified the hub gene SLC26A2 as playing a significant role in UC, and MHD demonstrates potential as a targeted therapeutic strategy for UC.
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DOI
PubMed
高影响因子
OPTICAL MATERIALS
·
2025
·
IF 4.2
Pei Zhang,Mengmeng Li,Yibo Zheng,Linjiao Ren,Zirui Qin,Qingfang Zhang,Rubin Qi,Jitao Zhang,Liying Jiang,Dongke Li
The isoreticular metal organic frameworks-3 (IRMOF-3)/non-stoichiometric thiol-ene (OSTE) and 2-aminoterephthalic acid (BDC-NH 2 )/OSTE composites were synthesized via a photo-induced click reaction. Interestingly, through polymerization with OSTE, both the fluorescence lifetime and intensity of IRMOF-3 increased. Moreover, its two lifetimes merged into one, which could be ascribed to the inhibition of the dynamic non-radiative quenching process by the OSTE network. In contrast, the ligand maintained a single lifetime with only minor changes. The dilution effect of the thiol-ene mixed solution could effectively reduce the static photo-induced electron transfer process between the ligand and toluene molecules. After the post-synthetic polymerization (PSP) treatment, the photoluminescence quantum yield (PLQY) of IRMOF-3 was increased from 7.2 % (in toluene) to 42.3 %, and that of the pure BDC-NH 2 ligand was significantly enhanced from 1.8 % (in toluene) to 76.0 %. Moreover, when a commercially available 370-nm light-emitting diode (LED) chip was individually encapsulated by the two composites, it could emit intense indigo light. This rapid PSP treatment via the OSTE polymer holds promise for application in other excellent luminescent MOFs.
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高影响因子
FOOD MICROBIOLOGY
·
2026
·
IF 5.4
Wenzhi Li,Jiling Ma,Youhua Long,Weizhen Wang,Xianhui Yin,Zhuzhu Zhang,Bingce Wang,Lu Yang,Hujun Qin
Botryosphaeria dothidea is one of the primary pathogens responsible for kiwifruit soft rot, leading to significant postharvest economic losses. Streptomyces spp., known for producing abundant volatile organic compounds (VOCs), have emerged as a crucial biological resource for controlling postharvest diseases. This study employed wheat grain cultures of Streptomyces albidoflavus SC-3 to produce VOCs, with the aim of systematically evaluating their antifungal mechanisms against B. dothidea . The VOCs emitted by SC-3 showed remarkable antifungal activity against B. dothidea , effectively inhibiting mycelial growth and suppressing sclerotia germination. Through optimization of culture conditions including inoculation volume, culture temperature, incubation time, and dosage of wheat grains, the antifungal efficacy of VOCs produced by SC-3 was significantly improved. Strain SC-3 VOCs reduced the pathogenicity of B. dothidea in kiwifruit, thereby delaying the progression of fruit soft rot. The VOCs induced abnormal hyphal morphology and compromised cell wall and membrane integrity of B. dothidea . Transcriptomic analysis further revealed that these VOCs primarily function by disrupting energy metabolism, impairing cell membrane integrity, and disturbing redox homeostasis-related metabolic pathways. GC-MS analysis identified three antifungal VOCs, including carvone, 3,5-di-tert-butylphenol, and 3-butylidenephthalide. Carvone exhibited the strongest inhibitory effect with EC 50 value of 0.03 μL mL −1 , suggesting that it serves as the key active compound against B. dothidea . In conclusion, Streptomyces albidoflavus SC-3 VOCs, primarily carvone, effectively control kiwifruit soft rot by inhibiting the pathogen B. dothidea through multiple mechanisms.
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PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2011
·
IF 2.733
Xiaofang Shen,Yan Cui,Yuehong Pang,He Qian
1-Hydroxypyrene (1-OHP) is a widely used biomarker for evaluation of polycyclic aromatic hydrocarbons (PAHs) exposure. In this paper, a 1-OHP sensor, combining pre-concentration and in situ electrochemical determination, was fabricated based on electropolymerized poly(3-methylthiophene) (P3MT). Direct electrochemical properties of 1-OHP on the P3MT modified glass carbon electrode (GCE) were investigated. A pair of well-defined reversible cyclic voltammetric peaks were observed at the P3MT/GCE with Δ E p of 30 mV. The surface coverage ( Г ) of 1-OHP was calculated to be 9.26 × 10 −11 mol cm −2 at the P3MT/GCE and the electron transfer coefficient α was estimated to be 0.53. P3MT offers π-conjugated system to adsorb 1-OHP via π–π stacking interaction. Meanwhile, P3MT films displayed good electrocatalytic activity to the oxidation of 1-OHP. The peak currents of 1-OHP obtained by differential pulse voltammetry were linear with the concentrations of 1-OHP in a range of 0.5–20.0 μM ( R = 0.9953) with a detection limit of 165 nM (S/N = 3) and a sensitivity of 12.72 μA μM −1 cm −2 . The sensor also exhibited good reproducibility (with a relative standard deviation of 1.2%) and long-term stability.
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高影响因子
MATERIALS & DESIGN
·
2017
·
IF 4.364
Quanfeng Tang,Haizeng Li,Yanfang Yue,Qinghong Zhang,Hongzhi Wang,Yaogang Li,Pei Chen
The electrolyte plays an important role in an electrochromic device (ECD), and an ideal electrolyte can greatly improve the electrochromic performance of the device. Here, we report the preparation of a 1-Ethyl-3-methylimidazolium tetrafluoroborate ([Emim]BF 4 )-doped Poly(methyl methacrylate) (PMMA)-based gel electrolyte for electrochromic applications. By the doping of the [Emim]BF 4 , the ionic conductivity of the gel electrolyte is improved (2.9 × 10 − 3 S/cm at room temperature and 10 − 2 S/cm at 40 °C). Most importantly, the addition of the [Emim]BF 4 could reduce the anodic reaction potentials in an ECD, which could enable ECD bleaching at smaller applied voltages and avoid the degradation of optical modulation induced by ion-trapping in tungsten oxide (WO 3 ) films. This novel electrolyte provides a promising platform for low anodic reaction potential electrochromic devices.
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高影响因子
CERAMICS INTERNATIONAL
·
2020
·Vol. 46
·期 13
·20810-20818
·
IF 3.83
Mengjing Liu,Sun-Wai Chiang,Xiaodong Chu,Jia Li,Lin Gan,Yanbing He,Baohua Li,Feiyu Kang,Hongda Du
Herein, oriented boron nitride (BN)/alumina (Al 2 O 3 )/polydimethylsiloxane (PDMS) composites were obtained by filler orientation due to the shear-inducing effect via 3-D printing. The oriented BN platelets acted as a rapid highway for heat transfer in the matrix and resulted in a significant increase in the thermal conductivity along the orientation direction. Extra addition of spherical Al 2 O 3 enhanced the fillers networks and resulted in the dramatic growth of slurry viscosity. This, together with filler orientation induced the synergism and provided large increases in the thermal conductivity . A high orientation degree of 90.65% and in-plane thermal conductivity of 3.64 W/(m∙K) were realized in the composites with oriented 35 wt% BN and 30 wt% Al 2 O 3 hybrid fillers. We attributed the influence of filler orientation and hybrid fillers on the thermal conductivity to the decrease of thermal interface resistance of composites and proposed possible theoretical models for the thermal conductivity enhancement mechanisms.
研究领域:
材料科学
·
高分子化学
·
热管理材料
·
先进制造
·
复合材料工程
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高影响因子
ACS Applied Energy Materials
·
2019
·
IF 0
Jing Yang,Zhen Huang,Peng Zhang,Gaozhan Liu,Xiaoxiong Xu,Xiayin Yao
Developing solid electrolytes with high lithium-ion conductivity is crucial to realize high-performance all-solid-state lithium batteries. The substitution of ions with larger ionic radius can enlarge the Li+ migration tunnels and therefore enhance the lithium-ion conductivity. In this work, Ti4+ is employed to partially replace Ge4+ in Li2O–Al2O3–GeO2–P2O5 glass-ceramics electrolyte in order to improve its conductivity. The highest total lithium-ion conductivity of 1.07 × 10–3 S cm–1 at room temperature is obtained from Li1.5Al0.5Ge1.5(PO4)3-7.5 wt % TiO2 sample sintered at 900 °C for 6 h. The bulk and grain boundary conductivities are 1.67 × 10–3 S cm–1 and 2.99 × 10–3 S cm–1, respectively, which are superior than that of the pristine Li1.5Al0.5Ge1.5(PO4)3 counterpart. Both bulk and grain boundary conductivities of the sample have been significantly improved, which could be attributed to the increase of bottleneck sizes of the Li+ migration tunnels and the decrease of grain boundary area. All-solid-state lithium batteries employing LiFePO4 as cathode and solid electrolyte as separator and ionic conductor are assembled. A reversible capacity of 132.3 mAh g–1 is delivered after 200 cycles under a current density of 0.1C with a capacity retention ratio of 91.1%, showing the solid electrolyte is ideal for all-solid-state lithium-battery applications.
研究领域:
材料科学
·
固体离子学
·
储能技术
·
电化学
·
陶瓷与玻璃
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DOI
RSC Advances
·
2015
·Vol. 5
·期 54
·43489-43495
·
IF 3.84
Yinghui Bian,Jinshe Chen,Shaotang Xu,Lijun Zhu,Yulu Zhou,Yuzhi Xiang,Daohong Xia
Novel metal-free tetra-(3-phenyprop-2-allyloxy) phthalocyanine (TPAO-Pc) was synthesized and characterized by nuclear magnetic resonance spectrum (1H NMR), MALDI-TOF MS, Fourier-transform infrared (FT-IR) and UV-Visible absorption (UV-Vis) spectra. The effects of concentrations and solvents on the properties of self-assembly were investigated via absorption and fluorescence spectra, transmission electron microscopy (TEM). TPAO-Pc was stable in most organic solvents, such as toluene, acetone and dimethylsulfoxide (DMSO). However, the TPAO-Pc exhibited the tendency of forming “face-to-face” stacking mode self-assemblies (H-aggregate) in DMSO–water and acetone–water mixed solutions. Self-assembly of the TPAO-Pc was also demonstrated by fluorescence spectra. The TEM images displayed the core–shell nanospheres and dendritic nanostructure of TPAO-Pc formed in the DMSO–water and acetone–water mixed solutions, respectively. The mechanism of the self-assemblies growth was proposed on the basis of the experimental results. The morphology of the TPAO-Pc self-assemblies was related with the selected solvent conditions and the aggregation time. H-bond, π–π interaction may be the main driving force for the formation of core–shell nanospheres and dendritic nanostructure.
研究领域:
材料科学
·
纳米技术
·
超分子化学
·
有机化学
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2018
·
IF 3.412
Yumeng Zhang,Yuanqi Lv,Lin Chen,Haizhou Wu,Yingyang Zhang,Zhiyao Suo,Shuxin Wang,Yuxin Liang,Xinglian Xu,Guanghong Zhou,Xianchao Feng
Nowadays, natural antioxidants abundant in polyphenols have been widely used to substitute synthetic antioxidants in meat products. In general, high doses of natural antioxidants are required to provide comparative antioxidant effects as synthetic antioxidants. Noticeably, the qualities of meat products can be jeopardized due to interactions between polyphenols and myofibrillar proteins (MPs). In this study, methyl-β-cyclodextrin was used to increase the polyphenol loading amount by preventing interactions between polyphenols and proteins. Solubility, electrophoresis, fluorescence spectroscopy, and surface hydrophobicity analyses indicated that methyl-β-cyclodextrin could dose-dependently inhibit epigallocatechin-3-gallate-induced attacks on MPs under oxidative stress. Gel strength, cooking loss, confocal laser scanning microscopy, dynamic rheological testing, and Raman spectrum during gelation were further analyzed to investigate the effects of methyl-β-cyclodextrin on the qualities of epigallocatechin-3-gallate-treated emulsion gel. Methyl-β-cyclodextrin addition prevented modification of the secondary structure of MPs caused by epigallocatechin-3-gallate. In consequence, the gel and emulsifying properties of MPs were significantly improved. Moreover, β-cyclodextrins could partly inhibit oxidative attacks on MPs and thus increase their solubility. These results indicated that methyl-β-cyclodextrin addition effectively enhanced epigallocatechin-3-gallate loading capacity in meat products.
研究领域:
食品科学与技术
·
蛋白质化学
·
多酚-蛋白质相互作用
·
氧化稳定性
·
功能食品
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高影响因子
危险品化学品经营许可证（带存储）