Polymer Chemistry
·
2013
·Vol. 5
·期 8
·2951-2960
·
IF 5.231
Minghui He,Guangxue Chen,Xun Huang,Ruixin Xu,Zhaohua Zeng,Jianwen Yang
N-Phthaloyltranexamic acid ammonium salt derivatives integrating with peroxides can invoke redox photopolymerization and propagating polymerization. A series of N-phthaloyltranexamic acid ammonium salt derivatives based on benzophenone, thioxanthen, and naphtha chromophores as novel photocaged bases were synthesized and characterized. In combination with a benzoyl peroxide initiator, these structures were able to initiate the amine-mediated redox photopolymerization of acrylates. In particular, the covalent binding of N-phthalimidoamino acid and type II chromophores (thioxanthone, benzophenone) improved remarkably the photoreactivity of photocaged bases (thioxanthen-DBU and benzophenone-DBU) compared to the parent compound. Furthermore, naphthal-DBU matches well the emission spectra of the mercury lamp with a dominant emission wavelength at 365 nm. More importantly, phthal-DBU & BPO as a new photocaged redox combination can invoke controlled redox polymerization within an irradiation time of 3 min. Finally, due to the persistent interaction of the produced longeval amine with peroxides, remarkable post conversion after irradiation, which is significant for preparation of photo-screened materials, was thus initially achieved in the redox photopolymerization.
研究领域:
材料化学
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高分子科学
·
有机化学
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DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 4
·655
·
IF 5.719
Wenjing Yu,Bo Liu,Xiaojiao Zhao
To develop high-performance microwave absorption materials with the features of lightweight, thin thickness, broad bandwidth, and strong absorption, an ultralight Ni3S2@N, S-codoped graphene aerogel with a density of 13.5 mg/cm3has been fabricated by the use of metal-organic frameworks (MOFs) to directly initiate the gelation of graphene oxide strategy. In such a strategy, dual-functional 1D Ni-MOF nanorods not only act as the gelation agent but also afford the doping elements (N and S) originated from the organic species and the precursor for metal sulfide. Due to the synergistic effects of good impedance matching and multiple losses, the optimal reflection loss (RL) of as-prepared Ni3S2@N, S-codoped graphene aerogel reaches −46.9 dB at 17.1 GHz with only 2.0 mm and ultralow filling content (1.75 wt%). The maximum effective absorption bandwidth (EAB) reaches 6.3 GHz (11.7–18.0 GHz) at 2.38 mm, covering the whole Ku band. Moreover, the value of EAB with the RL less than −30 dB can be tuned to 12.2 GHz (5.8–18 GHz) at the absorber thickness ranging from 1.9 to 5.0 mm. This work provides insight for rational design and fabrication of multicomponent-containing graphene aerogels, showing the potential application in lightweight and high-performance microwave absorption.
研究领域:
材料科学
·
电磁学
·
化学工程
✓ 已验证
DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
·
2022
·
IF 6.267
Fang Wang,Zhe Chen,Zhenzhou Zhu,Jia Guo
Antibiotics in pharmaceutical and aquaculture wastewater is a growing threat to the environment of world, due to the induction of drug-resistant bacteria and the harm to the aquatic organisms. Photocatalytic membrane, which has immobilized photocatalyst on membrane is an effective and environmentally friendly technology for antibiotics degradation. In this study, a novel photocatalytic membrane was prepared by loading ZnO/N-g-C 3 N 4 composite on commercial polymer membrane with glutaraldehyde as a crosslinker through pressure driven filtration. The loading of the photocatalyst over the membranes was validated by Fourier transform infrared spectroscopy, scanning electron microscope and X-ray photoelectron spectroscopy. The photocatalytic properties of ZnO/N-g-C 3 N 4 composite membrane were observed efficient for degradation of tetracycline, ciprofloxacin and ofloxacin in both immersion and filtration model under visible light (λ > 420 nm). Especially, a ZnO/N-g-C 3 N 4 loading amount of 1.12 g/cm 2 and glutaraldehyde concentration of 45% led to the degradation rate of 100% and 80% for tetracycline at 5 mg/L and 10 mg/L, respectively. Low trans-membrane pressure (0.005 MPa) and narrow membrane size (50 kDa) were favorable for antibiotics degradation in filtration model due to long reaction time on membrane surface. Construction and performance of ZnO/N-g-C 3 N 4 composite membrane might provide new strategy for energy saving wastewater treatment.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 6
·976
·
IF 5.719
Haiyan Qi,Qiuying Li,Jing Jing,Tao Jing,Chuntong Liu,Lixin Qiu,Rokayya Sami,Mahmoud Helal,Khadiga Ahmed Ismail,Amani H. Aljahani
In our study, a unique ratiometric fluorescent sensor for the rapid detection of arginine (Arg) and acetaminophen (AP) was constructed by the integration of blue fluorescent N-CDs and yellowish-green fluorescent calcein. The N-CD/calcein ratiometric fluorescent sensor exhibited dual emission at 435 and 519 nm under the same excitation wavelength of 370 nm, and caused potential Förster resonance energy transfer (FRET) from N-CDs to calcein. When detecting Arg, the blue fluorescence from the N-CDs of the N-CD/calcein sensor was quenched by the interaction of N-CDs and Arg. Then, the fluorescence of our sensor was recovered with the addition of AP, possibly due to the stronger association between AP and Arg, leading to the dissociation of Arg from N-CDs. Meanwhile, we observed an obvious fluorescence change from blue to green, then back to blue, when Arg and AP were added, exhibiting the “on–off–on” pattern. Next, we determined the detection limits of the N-CD/calcein sensor to Arg and AP, which were as low as 0.08 μM and 0.02 μM, respectively. Furthermore, we discovered that the fluorescence changes of the N-CD/calcein sensor were only responsible for Arg and AP. These results suggested its high sensitivity and specificity for Arg and AP detection. In addition, we have successfully achieved its application in bovine serum samples, indicating its practicality. Lastly, the logic gate was generated by the N-CD/calcein sensor and presented its good reversibility. Overall, we have demonstrated that our N-CD/calcein sensor is a powerful sensor to detect Arg and AP and that it has potential applications in biological analysis and imaging.
研究领域:
生物化学
·
分析化学
·
医学检测
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2015
·
IF 2.912
Jun Huang,Haihua Xie,Sheng Hu,Tian Xie,Jinyan Gong,Chengjun Jiang,Qing Ge,Yuanfeng Wu,Shiwang Liu,Yanli Cui,Jianwei Mao,Lehe Mei
Chitosan was prepared by alkaline N-deacetylation of β-chitin from squid pens, and N-carboxyethylated derivatives (N-CECS) with different degrees of substitution (DS) were synthesized. The carboxyethylation of the polysaccharide was identified by Fourier transform infrared, 1H and 13C nuclear magnetic resonance (NMR), and X-ray diffraction analyses. The DS of the derivatives was calculated by 1H NMR and elemental analysis. All three N-CECS samples showed good water solubility at pH > 6.5. The antioxidant properties and bile acid binding capacity of the derivatives were studied in vitro. The highest bile acid binding capacity of all N-CECS reached 36.9 mg/g, which was 2.6-fold higher than that of chitosan. N-CECS showed a stronger scavenging effect on 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical ability, and EC50 values were below 2 mg/mL. The scavenging ability of N-CECS against superoxide radicals correlated well with the DS and concentration of N-CECS. These results indicated that N-carboxyethylation is a possible approach to prepare chitosan derivatives with desirable in vitro biochemical properties.
研究领域:
生物化学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2017
·
IF 1.9
Kwanghyok Jong,Benzhi Ju,Shufen Zhang
In this study, a novel type of pH-responsive polymer PyHES-NAC (2-hydroxy-3-(2-propynyloxy) propyl hydroxyethyl starch (PyHES)) – (N-acetyl-cysteine (NAC)) was synthesized. First, PyHES was prepared via hydrophobic modification of hydroxyl groups in hydroxyethyl starch (HES) with propynylglycidyl ether (PGE), and then pH-responsive carboxylic acid group was connected to propynyl group via thiol-yne click reaction with NAC. Aqueous PyHES-NAC solutions exhibited a good transference between hydrophobic (or self-assembly) and hydrophilic static along with the change of pH value and protective properties of drugs under acidic conditions. 10.0% DOX was released under artificial gastric fluid after 2 h, whereas an immediate release (above 80%) was observed under artificial intestinal fluid. Drug loading capacity of PyHES-NAC was increased by the increase of degree of substitution (DS) of hydrophobic propynyl groups in PyHES, and 41 wt% DOX Loading capacity was the highest value in our study area.
研究领域:
药剂学
·
生物材料学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF TOXICOLOGY
·
2023
·
IF 2.2
Xu Fang,Wei Zhu,Huiying Zhao,Wencheng Yin,Xiao Song,Fengxin Liu
Lacto-N-triose II (LNT II), an essential human milk oligosaccharide and precursor to lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT), was evaluated for safety. Genotoxicity was assessed through in vitro tests including Bacterial Reverse Mutation Test and mammalian cell micronucleus test, and a subchronic oral gavage toxicity study was conducted on juvenile Sprague-Dawley rats. In this study, LNT II was administered at dose levels of 0, 1,500, 2,500, or 5,000 mg/kg body weight (bw)/day for 90 days, followed by a 4-week treatment-free recovery period. LNT II was non-genotoxic in the in vitro assays. No compound-related effects were observed across all dosage levels based on various measures, including clinical observations, body weight gain, feed consumption, clinical pathology, organ weights, and histopathology. Consequently, the highest dosage of 5,000 mg/kg bw/day was established as the no-observed-adverse-effect-level (NOAEL). These results suggest the safe use of LNT II in young children formula and as a food ingredient, within the limits found naturally in human breast milk.
研究领域:
营养学
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毒理学
·
儿科学
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Jia-Xi Shen,Rui Guo,Miao-Yan Wang,Hai-Liang Zhu,Hao-Xiang Jiang,Han-Bin Cui,Kai Wang
Cardiovascular disease, a chronic and progressive arterial wall disease, is increasingly recognized for its clinical significance. Aminopeptidases N (APN), crucial in the pathophysiological processes of vulnerable plaque, have been linked to endothelial dysfunction, oxidative stress, and plaque formation, thus highlighting their potential as biomarkers for disease progression. However, current detection methods for APN in body fluids and in vivo have limitations, including insufficient sensitivity and specificity, time delays, and the inability to directly reflect enzyme activity in plaques. To address these challenges, we developed an optical probe, HD-APN, for in vivo imaging of aminopeptidases, providing a potential implementation in cardiovascular disease. Our work demonstrated the applicability of HD-APN for specific monitoring of aminopeptidase levels in plaques and serum, shedding light on its potential for further research in cardiovascular disease.
研究领域:
心脏病学
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分子生物学
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生物医学工程
·
成像科学
✓ 已验证
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Shuhui Liang,Manman He,Jingjing Guo,Jie Yue,Xipeng Pu,Bo Ge,Wenzhi Li
The BiOBr:Yb 3+ ,Er 3+ /g-C 3 N 4 (BYE/CN) p-n junction photocatalysts were successfully fabricated by a stepwise method. Experimental results show that Er 3+ /Yb 3+ were successfully doped into BiOBr lattice. As-obtained BYE/CN exhibited strong NIR light absorption and upconversion emission from NIR to UV–visible due to the upconversion transition of Er 3+ . The p-n junction was constructed due to the appropriate alignment band structure of BYE and g-C 3 N 4 , which distinctly suppresses the recombination rate of electron-hole pairs. Compared with pure BYE and CN, as-synthesized BYE/CN samples exhibit distinctly improved photoactivities under the irradiation of visible or NIR light, which can be attributed to the upconversion effect of Er 3+ and the construction of p-n junction. This result may provides a promising system for efficient harvest of the NIR light, which will contribute to the utilization of solar energy in the future.
研究领域:
材料科学
·
光催化
·
能源利用
✓ 已验证
DOI
高影响因子
Catalysis Science & Technology
·
2019
·Vol. 9
·期 20
·5651-5659
·
IF 5.726
Hossain M. Shahadat,Hussein A. Younus,Nazir Ahmad,Md. Abdur Rahaman,Zafar A. K. Khattak,Serge Zhuiykov,Francis Verpoort
Water-soluble homogeneous nickel catalysts have been rarely investigated for catalytic water oxidation as compared to their heterogeneous counterparts. Herein, we report homogenous electrochemical water oxidation by a nickel(II) complex, ([NiL](PF6)2 (L = bis(2-pyridyl-methylimidazolylidene)methane), based on a macrocyclic N-heterocyclic carbene/pyridine hybrid ligand under neutral and alkaline conditions. The catalyst displayed the stable catalytic current of 0.65 mA cm−2 at the overpotential of 0.80 V (∼0.55 V at GCE for CV) with a ∼93% Faradaic efficiency at pH 9.0 for oxygen evolution in long-term bulk electrolysis. The CV, UV-vis, ESI-MS, SEM, and EDX results demonstrated that the catalyst was impressively stable even after long-term controlled potential electrolysis (CPE) (11 h) and homogeneous in nature. The synthesis of this catalyst is straightforward, and its complex is air and moisture stable. To the best of our knowledge, this is the first study on the investigation of a Ni–NHC complex for water oxidation under aqueous conditions (acetate/phosphate). According to the literature, the role of the phosphate ion in homogenous nickel-catalysed water oxidation was found to vary from catalyst poisoning to activation. Interestingly, the catalytic activity of our catalyst in phosphate buffer was significantly higher than that with acetate ions at the same pH value; this might indicate the key role of phosphate ions as proton acceptors, which boosted the catalyst activity via enhanced PCET during catalysis.
研究领域:
无机化学
·
电化学
·
催化化学
·
配位化学
·
能源化学
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Yu Lu,Lujia Sun,Cheng Li,Xiaoqin Wang,Wenqing Li,Tong Zhao,Linjuan Huang,Zhongfu Wang
Extensive cross-allergic reactivity exists among food-borne plants. As most allergens are glycoproteins, protein sensitization has been extensively studied. However, little attention has been given to the glycan component of glycoproteins. Here, we qualitatively and quantitatively compared the N -glycans of eight cross-reactive plant glycoproteins derived from peach pollen, soy, pine nut, cashew nut, pistachio, walnut, almond, and hazelnut. Cross-reactive carbohydrate determinants (CCDs) were widely present in the allergic glycoproteins according to the following order: pollen > soybean > pistachios > pine nuts > walnuts > cashews > hazelnuts > almonds. The N -glycan structure presented clear differences between the germplasm and vegetative tissue. Importantly, fucosylation and xylosylation levels correlated positively with extensive cross-reactivity between plants, which suggests that CCDs may be one of the causes of cross-allergy. This result provides the foundation for mechanistic studies on plant-derived CCDs as a source of food cross-allergies.
研究领域:
生物化学
·
免疫学
✓ 已验证
DOI
高影响因子
ENZYME AND MICROBIAL TECHNOLOGY
·
2022
·
IF 3.705
Shi-Wei Zhao,Qian Zhou,Neng-Bing Long,Rui-Feng Zhang
A novel polymer support was prepared by curing of epoxy resin in ethanol solution in the macropores of a melamine sponge. The produced polymer gel could uniformly deposit on the surface of melamine in either porous or nonporous morphology. The composite sponge with porous coating can be used as a large-sized and well-mass transferred support for the immobilization of β-galactosidase from Bacillus circulans through method of adsorption and crosslinking, and a column reactor was made for the preparation of N-acetyllactosamine in a sealed circulation way. The porosity and specific surface area of the support were 91.6 % and 46 m 2 /g, respectively. The loading amount and the specific activity of immobilized β-galactosidase under the optimal immobilization conditions were 41.2 mg/g support and 16.5 U/mg protein , respectively. In the biosynthesis of N-acetyllactosamine lactose and N-acetylglucosamine were used as donor and acceptor, respectively. Under optimized conditions the N-acetyllactosamine yield reached 54 % within 150 min at 50 °C. After 10 cycles, the immobilized β-galactosidase retained 70 % of the original activity.
研究领域:
生物化学
·
酶工程
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）