JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
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2024
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IF 3.3
Min Zheng,Chen Xie,Dan Ye,Yong Chen,Ziyao Wang,Le Wang,Fang Xiong,Sheng Zhang,Qiang He,Hui Wu,Zhinong Wu,Hongfu Zhou,Ling Li,Jun Xing,Xiaolei Miao
BACKGROUND Qingzhuan dark tea polysaccharides (QDTP) have been complexed with Zinc (Zn) to form the Qingzhuan dark tea polysaccharides-Zinc (QDTP-Zn) complex. The present study investigated the protective effects of QDTP-Zn on ulcerative colitis (UC) in mice. The UC mouse model was induced using dextran sodium sulfate (DSS), followed by oral administration of QDTP-Zn (0.2 and 0.4 g kg −1 day −1 ). RESULTS QDTP-Zn demonstrated alleviation of UC symptoms in mice, as evidenced by a decrease in disease activity index scores. QDTP-Zn also regulated colon tissue injury by upregulating ZO-1 and occludin protein expression, at the same time as downregulating tumor necrosis factor-α and interleukin-6β levels. Furthermore, QDTP-Zn induced significant alterations in the abundance of bacteroidetes and firmicutes and notably increased levels of short-chain fatty acids (SCFAs), particularly acetic acid, propionic acid, and butyric acid. CONCLUSION In summary, QDTP-Zn exhibits therapeutic potential in alleviating enteritis by fortifying the colonic mucosal barrier, mitigating inflammation and modulating intestinal microbiota and SCFAs levels. Thus, QDTP-Zn holds promise as a functional food for both the prevention and treatment of UC. © 2024 Society of Chemical Industry.
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Analytical Methods
·
2025
·
IF 2.6
Jiaxi Deng,Yiyao Luo,Jia Zheng,Zirui Yuan,Yi Ma,Huibo Luo,Xiaogang Luo,Danqun Huo,Changjun Hou
Baijiu represents the pinnacle of traditional Chinese culinary culture. The influence of Baijiu is evident in various literary works, rituals and banquets, dishes and healthcare, and numerous other areas. The reduction of substances plays a pivotal role in the flavor, aroma, and quality control of Baijiu. Therefore, the present work focuses on Baijiu and the reducing substances in it. In this study, CDs@ZrFe-MOF and three distinct catalase nanase substrates (ABTS, OPD, and TMB) were employed to create fluorescence and colorimetric dual-mode sensor arrays. The oxidation of the enzyme substrate into the appropriate oxidation substrate is facilitated by CDs@MOF in the presence of H₂O₂. The reducing substance effectively inhibits the formation of the oxidation substrate, resulting in alterations in fluorescence and UV intensity. The dual-mode sensor array was found to be effective in detecting 15 different types of reducing chemicals. Furthermore, the colorimetric and fluorescence sensor array demonstrated exceptional detection capability in detecting 19 different types of Luzhou-flavor liquor samples, achieving a 100% accuracy rate. This study will provide an accurate and rapid method for differentiating Baijiu.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Le Gou,Zhentao Ping,Liyi Dai,Yuanyuan Wang
Organic acids are commonly used additives in the hydrothermal carbonization (HTC) of sewage sludge (SS). Previous studies have demonstrated that organic acids can effectively increase the carbon content of hydrochar, reduce its nitrogen content, and improve its combustion performance. Due to significant differences in molecular structure and chemical reactivity among organic acids with varying carbon chain lengths, they may exert distinct influences on hydrochar yield, carbon content, and combustion behavior. However, there remains a lack of systematic research on the effects of organic acids with varying carbon chain lengths during the HTC process. In this study, an orthogonal experimental design was employed to investigate the influence of C1 to C9 organic acids on the carbon content of hydrochar under various temperatures (170–230 °C) and concentrations (0.1–0.5 mol/L). The results showed that as the carbon chain length increased, organic acids were more likely to incorporate into the hydrochar structure through chemical reactions, resulting in a gradual increase in both carbon content and calorific value. Furthermore, the addition of long-chain organic acids led to a reduction in nitrogen content and enhancement of the combustion characteristics of the hydrochar. Meanwhile, long-chain organic acids were also beneficial for the recovery of nutrients from the aqueous phase. These findings provide a systematic reference for improving hydrochar quality and promoting aqueous phase resource recovery in the HTC of SS using organic acids.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Cong Zhang,Rui Cui,Liang Qi,Minhua Zong,Canyu Zhang,Yufei Cao,Wenyong Lou
Pickering emulsions, with their high specific surface area, serve as promising nanoreactors for highly efficient biocatalysis. These emulsions also provide an effective way to integrate multiple incompatible catalysts, such as enzymatic catalysis and metal catalysis, paving the way for green synthetic chemistry in the future. In this study, we used agar, an accessible and biodegradable material, to produce agar nanoparticles with varying properties by modifying them with phthalic anhydride. The agar nanoparticle-stabilized Pickering emulsion greatly enhanced the lipase-catalyzed esterification reaction, demonstrating 392- and 38-fold improvements compared with monophasic and biphasic catalytic systems, respectively. After 10 reuse cycles of the Pickering emulsion, the product yield remained 86.5 %, with the relative enzyme activity being 86.6 %. Furthermore, we successfully integrated lipase-catalyzed esterification and Pd-catalyzed C C coupling reactions within the Pickering emulsion. By increasing the interfacial reaction area and reducing the mass transfer distance, this system improved the efficiency of the chemoenzymatic cascade reaction. The agar-based Pickering emulsion provides a promising platform for efficient and sustainable green synthesis, utilizing enzyme catalysts or chemical-biological hybrid catalysts.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Lingqi Shen,Yuan Yan,Xiaoyan Jiang,Xuerong Yang,Zhihui Zhang,Zuguang Li
As new green solvents, the low volatility of deep eutectic solvents (DESs) limits their development in natural product extraction. In this work, a series of novel lower critical solution temperature (LCST) type temperature-responsive DESs (TRDESs) were prepared and applied to the extraction of carotenoids from tomato. The highest yields (408.85 ± 4.97 μg/g of lycopene, 68.78 ± 2.00 μg/g of β-carotene) were obtained under the following conditions: extractant DES-16 (methyl 1-benzylpiperidine-4-carboxylate: valeric acid: heptanoic acid = 2:1:1), solid-liquid ratio 1:58 g/mL, extraction temperature 68 °C, and extraction time 44 min. Utilizing the temperature response characteristics of TRDESs, the separation of carotenoids and TRDESs was achieved in a mild way. Upon analysis, hydrophilic polysaccharides were simultaneously extracted and retained in water through the recovery experiment. Green Analytical Procedure Index (GAPI) proved the greenness of the method. This work provides new ideas for DESs in the extraction of natural products.
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AICHE JOURNAL
·
2025
·
IF 4
Qinghua Liu,Guoxuan Li,Chengmin Gui,Minghao Song,Fei Zhao,Shengchao Yang,Zhigang Lei,Pan Xu
Deep eutectic solvents (DESs) were regarded as promising absorbents in many absorption processes. Here, we use randomly methylated β -cyclodextrin (RAMEB) to further improve the absorption capacity of DESs for aromatic VOCs. We found benzene and toluene vapor pressures obviously decreased after adding 2% RAMEB (molar fraction) to DESs. Dynamic absorption experiments also confirmed this enhancement effect; the dynamic absorption efficiency for benzene and toluene increased by 6.12% and 9.23%, respectively, at a 5 mL/min solvent rate. Water was used to reduce the viscosity of DESs; the humidity and regeneration stability were evaluated experimentally. At the molecular level, the strong host–guest interactions between RAMEB and aromatic VOCs were identified as the main reason for improving the absorption capacity of DESs. Additionally, the roles of hydrogen bond donor and acceptor molecules were analyzed. π–π stacking and CH–π interactions were also identified as significant contributors to the aromatic VOCs absorption process.
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Frontiers in Pharmacology
·
2025
·
IF 4.8
Yuhang Xu,Jing Li,Mengyao Cui,Xiaoliang Li,Hongyan Zhai,Deling Wu,Xiaoqin Chu
Introduction: Cinnamomi Ramulus (CR) is the dried bark of Cinnamomum cassia Presl, Lauraceae. Puerariae Lobatae Radix (PLR) is the dried root of the Pueraria lobata (Wild.) Ohwi, Leguminosae. This Chinese herb couple come from the classic formula “Gui Zhi Ge Gen Tang,” which is included in the TCM classic “Treatise on Febrile Diseases.” Our previous studies have found that CR related herbal compound and PLR related herbal compound are useful in improving type 2 diabetes mellitus (T2DM), which is expected to be an antidiabetic candidate with fewer side effects. However the mechanism of action of CR-PLR on T2DM has not yet been fully elucidated.Methods: The decoction of CR-PLR was prepared by aqueous extraction method and the composition of it was analyzed using UPLC-Q-TOF-MS and HPLC. The T2DM model was established by intraperitoneal injection of streptozotocin, and the groups of drug administration were metformin, CR, PLR and CR-PLR groups, with continuous gastric gavage for 6 weeks, and the serological indexes were detected by ELISA. The abundance of rats’ gut flora was detected by 16s rDNA sequencing, and changes in the content of short-chain fatty acids (SCFAs) in feces of rats were detected by GC-MS; and the expression of G protein-coupled receptor43 (GPR43) and glucagon-like peptide-1 (GLP-1) proteins in colonic tissues of rats were detected by Western Blot. The pharmacokinetic behavior of CR-PLR was investigated in both normal and T2DM model rats. Caco-2/HT29 co-culture cell model was established in vitro, transepithelial electrical resistance (TEER) and ALP activity of epithelial cells were measured to evaluate cell model integrity and cell polarization, Alcian blue staining was used to verify the presence of mucus production, and CCK-8 was used to screen drug safe concentration. The bidirectional transport of puerarin was studied to investigate the transport mechanism of puerarin and the effect of leuric acid on puerarin transport.Results and discussion: The results indicated that CR-PLR can stimulate intestinal flora, increase the content of SCFAs, activate intestinal GPR43 protein, and promote the secretion of GLP-1 in intestinal L cells, which plays a therapeutic role in the treatment of T2DM. Additionally, cytology and pharmacokinetics experiments have proved that cinnamic acid (CA) can enhance the absorption and transport of puerarin (PUR) by inhibiting the efflux effects mediated by P-gp and MRP efflux transporters. The present study exhibites the scientific and reasonable menaning of this novel Chinese herb couple treating T2DM from the perspecives of pharmacodynamics and pharmacokinetics.
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APPLIED SURFACE SCIENCE
·
2025
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IF 6.9
Hongyang Ye,Zengyao Guo,Suli Wu,Bingtao Tang,Shufen Zhang
Monodisperse titanium dioxide (TiO 2 ) colloidal nanospheres, which possess a high refractive index (RI), are ideal building blocks for fabricating colloidal photonic crystals (CPCs) with structural colors. However, the intrinsic surface property, especially the low surface charge density, hinders them from assembling into CPCs with long-range ordered structures. Herein, we develop a surface modification strategy aimed at improving the surface potential of monodisperse TiO 2 nanospheres by utilizing vinyltriethoxysilane (VTES) as the modifier. XPS analysis reveals that the VTES molecules attach to the TiO 2 surface via Ti-O-Si chemical bonds and the presence of additional Si-OH groups, which can increase the surface potential. The as-synthesized VTES-modified TiO 2 nanospheres are subjected to calcination to increase their RI by crystallizing into the anatase phase. CPCs with bright and tunable structural colors throughout the visible range are successfully fabricated by utilizing the monodisperse VTES-modified TiO 2 or anatase-TiO 2 nanospheres as building blocks by self-assembly through a dip coating method.
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ACS Earth and Space Chemistry
·
2025
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IF 2.9
Yaru Song,Minglan Xu,Jianlong Li,Narcisse Tsona Tchinda,Kun Li,Lin Du
Atmospheric release of nuclear wastewater results in the introduction of radionuclides into seawater. These radionuclides can be transported back to the atmosphere by interacting with organic matter at the surface of marine aerosol. Organic molecules, such as organic acids (OAs) and alcohols, the primary components of the organic coating on marine aerosol, play a crucial role in this process. However, the discriminated mechanisms of the interactions of these OAs and organic alcohols at the marine aerosol surface urgently need to be explored. This study uses a Langmuir trough to mimic the marine aerosol surface and investigates the interactions of several OAs (formic acid, hexanoic acid, heptanoic acid, octanoic acid, and nonanoic acid) and dodecanol at seawater-relevant ratios. It was found that upon their addition, metal ions (Ba2+, Co2+, Mn2+, Cs+, Sb3+, Sr2+, Rh3+, Ru3+, and La3+) acting as proxies of radionuclides effectively interacted with the carboxyl headgroups of OAs, which was manifested as a significant increase in the carboxylate asymmetric stretch. This asymmetric stretching vibration is significantly increased with the metal ion concentration and enrichment. Furthermore, the apparent surface binding affinity of metal ions with hexanoic acid is significantly higher than that with nonanoic acid, by a factor of ∼1.95. These findings are significant for understanding how metal ion enrichment at the air-sea interface influences the behavior and fate of radionuclides in the marine atmosphere. Additionally, this study provides new insights into the complex interactions between organic compounds and metal ions, offering valuable perspectives and methodologies for advancing research in marine chemistry and environmental science.
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Food Chemistry-X
·
2025
·
IF 8.2
Zhuyu Yang,Zefan Chen,Weijia Zhang,Jinlin Wang,Fan Bai,Ruichang Gao,Yujin Li,Jian Li,Yuanhui Zhao,Xinxing Xu
This is the first comprehensive comparison of key odorants and sensory properties of various caviar with different breeding environments, processing conditions, and grades of quality. Ten aroma attributes were identified and rated by sensory descriptive analysis. 47 and 50 volatile compounds were identified by two aroma extraction methods (SPME, SAFE) combined with GC–MS, respectively. 27 potential key aroma-active compounds were quantitated and further screening through AEDA and OAV calculation. Finally, 21 key aroma active compounds (OAV > 1, FD ≥ 9) were screened, including butanal, hexanal, ( Z )-4-heptenal, ( Z )-2-penten-1-ol, 2-nonanone, nonanal, 1-octen-3-ol, 2-ethyl-1-hexanol, benzaldehyde, acetic acid and other compounds. Recombination and omission tests verified that these compounds played an important role in the overall aroma profile of different caviar samples. The different contribution of key volatile aroma compounds to the overall aroma system of caviar resulted in the difference of caviar flavor quality.
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MOLECULES
·
2025
·Vol. 30
·期 11
·2429
·
IF 4.6
Wei Wang,Xiangyao Chen,Wen-Can Huang,Simiao Di,Jie Luo
This study presents a multilayer magnetic Janus sub-micrometric particle (MMJSP) as a nanoreactor for lipase catalysis. The core of the nanoparticle is constructed from a core-shell Fe3O4@SiO2framework, which serves as a precursor for the sequential amino and aldehyde modifications using 3-aminopropyltriethoxysilane and benzaldehyde. Following localized etching and subsequent modification with N,N-dimethyldodecylamine, a Janus nanoparticle with distinct hydrophilic and hydrophobic domains is synthesized. The resulting MMJSP demonstrates a stable attachment to the reaction interface and significantly enhances lipase performance, exhibiting 1.4-fold and 1.6-fold enhancements in activity after immobilization during 1 h hydrolysis and 24 h esterification reactions, respectively. Additionally, the storage stability of the immobilized lipase is improved by 100% over a period of 30 days. Reusability assessments reveal that the immobilized enzyme retains 80.7% activity after 10 cycles of esterification and 80.6% after 50 cycles of hydrolysis, with the magnetic properties allowing for rapid separation and recovery of the immobilized enzyme.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
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IF 5.4
Ye Zhang,Yujie Qiang,Wenyue Zhang,Seeram Ramakrishna,Abdolreza Farhadian,Ying Jin
Ionic liquids (ILs) have gained attention as green corrosion inhibitors due to their design flexibility and tunability. In this study, two imidazolium-based ILs, BPDB and BADB, were synthesized and systematically evaluated for their corrosion inhibition performance in acid cleaning applications. First, Density Functional Theory (DFT) calculations were employed to predict inhibition efficiency, identifying nitrogen atoms as key adsorption sites. The lower adsorption energy of BADB suggested a stronger inhibition capacity, attributed to the introduction of amino substituents. Based on these theoretical predictions, electrochemical tests at 0.1 mM confirmed high inhibition efficiencies of 93.8 % for BPDB and 96.3 % for BADB, validating the superior performance of BADB. Experimental surface analysis further supported these findings, revealing that nitrogen-containing organic fragments were adsorbed onto the Fe surface. To gain deeper mechanistic insights, Ab Initio Molecular Dynamics (AIMD) simulations were conducted to investigate the dynamic bonding evolution. Coordination number analysis demonstrated that BADB molecules formed stable Fe-N-Fe bonds, ensuring robust and sustained adsorption on the metal surface. By integrating theoretical predictions, experimental validation, and molecular-scale simulations, this study provides a comprehensive understanding of IL-based corrosion inhibition mechanisms. The findings offer valuable guidance for designing high-performance, eco-friendly corrosion inhibitors for industrial acid cleaning applications.
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危险品化学品经营许可证（带存储）