Foods
·
2023
·Vol. 12
·期 12
·2302
·
IF 5.2
Yuanfei Li,Huadi Mei,Yanchen Liu,Zhenming Li,Hammad Qamar,Miao Yu,Xianyong Ma
Consumer demand for tasty and quality meat has been quickly increasing. This study investigated how dietary supplemented rutin affects meat quality, muscle fatty acid profile, and antioxidant capacity in the Chinese indigenous Qingyuan partridge chicken. A cohort of 180 healthy 119-day-old chickens was subjected to a randomized assignment into three groups, identified as the control, R200, and R400 groups, with respective supplementation of 0, 200, and 400 mg/kg of rutin. The results revealed insignificance in growth performance, namely, average daily gain, average daily feed intake, and feed-to-gain ratio, across the various treatment groups (p> 0.05). Nevertheless, dietary rutin supplementation increased (p< 0.05) breast muscle yield and intramuscular fat content in breast muscle and decreased (p< 0.05) drip loss in breast muscle. Rutin supplementation increased (p< 0.05) the content of high-density lipoprotein but decreased (p< 0.05) the contents of glucose, triglyceride, and total cholesterol in serum. Rutin supplementation increased (p< 0.05) the levels of DHA (C22:6n-3), total polyunsaturated fatty acids (PUFAs),n-3 PUFAs, decanoic acid (C10:0), the activity of Δ5 + Δ6 (22:6 (n− 3)/18:3 (n− 3)), and the ratio of PUFA/SFA in breast muscle but decreased (p< 0.05) the level of palmitoleic acid (C16:1n-7), the ratio ofn-6/n-3 PUFAs, and the activity of Δ9 (16:1 (n− 7)/16:0). Rutin treatment also reduced (p< 0.05) the contents of malondialdehyde in serum and breast muscle, and increased (p< 0.05) the catalase activity and total antioxidant capacity in serum and breast muscle and the activity of total superoxide dismutase in serum. Additionally, rutin supplementation downregulated the expression ofAMPKαand upregulated the expression ofPPARG,FADS1,FAS,ELOVL7,NRF2,andCATin breast muscle (p< 0.05). Convincingly, the results revealed that rutin supplementation improved meat quality, fatty acid profiles, especiallyn-3 PUFAs, and the antioxidant capacity of Qingyuan partridge chickens.Keywords:rutin supplementation;antioxidant capacity;fatty acid profile;lipid metabolism;meat quality;Chinese yellow-feathered broiler;Qingyuan partridge chickens
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Yujiao Sun,Xushuang Yuan,Zhaojun Luo,Yungang Cao,Shuai Liu,Yang Liu
Liquid-state fermentation (LSF) of tea leaves is a promising way to obtain tea-based nutraceutical products rich in various bioactive compounds. In the study, the changes of bioactive compounds, tea pigments and complex metabolites from LSF of primary dark tea, green tea and white tea infusions with Aspergillus cristatus were determined. Chemical analyses revealed that soluble sugars, monosaccharide composition, total polyphenols, total flavonoids, free amino acids, soluble proteins and tea pigments were changed in different ways. An untargeted metabolomic analysis and ribonucleic acid sequencing (RNA-seq) based transcriptomic analysis were performed to investigate the metabolic differentiation and clarify the key differentially expressed genes (DEGs, fold change >2 and p < 0.05), showing that amino acid metabolism, carbohydrate metabolism and lipid metabolism were the most enriched pathways during A. cristatus fermentation of primary dark tea, green tea and white tea infusions. In addition, glycerophospholipid metabolism, linoleic acid metabolism and phenylalanine metabolism were greatly accumulated in the fermentation of primary dark tea and white tea infusions; Pyruvate metabolism, glycolysis/gluconeogenesis, fatty acid degradation, tyrosine metabolism, phenylalanine, tyrosine and tryptophan biosynthesis and valine and leucine, isoleucine degradation were greatly accumulated in the fermentation of primary dark tea and green tea infusions; Starch and sucrose metabolism was greatly accumulated in the fermentation of green tea and white tea infusions; Galactose metabolism was significantly enhanced in the fermentation of primary dark tea infusion; Amino sugar and nucleotide sugar metabolism, sphingolipid metabolism and alanine, aspartate and glutamate metabolism were significantly enhanced in the fermentation of green tea infusion. Besides, some other pathways involving aminobenzoate degradation, biosynthesis of cofactors, pyrimidine metabolism, benzoxazinoid biosynthesis and phenazine biosynthesis, tropane, piperidine and pyridine alkaloid biosynthesis and flavone and flavonol biosynthesis also differed from each other. These findings support that A. cristatus plays a vital role in the biochemical and genetic regulation of metabolite profile, and could be considered a potential prospect for better use of A. cristatus on different kinds of tea materials.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Chemistry-X
·
2023
·
IF 6.1
Xiao-Hua Zhang,Xiang-Dong Qing,Jing-Jing Zheng,Yan Yu,Jiaojiao Huang,Chao Kang,Zhi Liu
In this study, an accurate, rapid, green, and environment friendly method for the extraction and quantitative analysis of flavonoids in honey was established by using the aqueous two-phase extraction combined with the chemometrics-assisted HPLC-DAD. The first purpose of this study was to extract seven flavonoids in five different types of honey using alcohol/salt aqueous two-phase system (ATPS). The system with 2.82 mL sodium citrate (30%), 1.58 mL water, and 3.10 mL isopropanol, showed the highest flavonoids extraction yields in the top phase (87.66–101.50%). Additionally, the three-way array of honey samples based on HPLC-DAD was decomposed mathematically by the alternating trilinear decomposition (ATLD) algorithm to obtain reasonable chromatograms, spectra, and concentration profiles for each analyte. Compared with the traditional solid-phase extraction method, the ATPS-ATLD-based method showed satisfactory spiked recoveries, lower limit of detection, and higher sensitivity, further verifying its accuracy and stability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Foods
·
2023
·Vol. 12
·期 12
·2326
·
IF 5.2
Juan Liu,Yongling Lu,Bo Si,Anqi Tong,Yang Lu,Lishuang Lv
Acrolein (ACR) is a toxic unsaturated aldehyde that is produced during food thermal processing. Here, we investigated the synergistic effect of polyphenols in binary, ternary, and quaternary combinations on ACR by the Chou–Talalay method, and then explored the synergistic effect of cardamonin (CAR), alpinetin (ALP), and pinocembrin (PIN) in fixed proportion fromAlpinia katsumadaiHayata (AKH) combined with curcumin (CUR) in the model, and roasted pork using LC–MS/MS. Our results showed that their synergistic effect depended on the intensification of their individual trapping ACR activities, which resulted in the formation of more ACR adducts. In addition, by adding 1% AKH (as the carrier of CAR, ALP, and PIN) and 0.01% CUR (vs. 6% AKH single) as spices, more than 71.5% (vs. 54.0%) of ACR was eliminated in roast pork. Our results suggested that selective complex polyphenols can synergistically remove the toxic ACR that is produced in food processing.Keywords:acrolein;cardamonin;alpinetin;pinocembrin;Alpinia katsumadaiHayata;curcumin
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Qiang Lyu,Wanying Zheng,Qiyuan Shan,Lichuang Huang,Yiwen Wang,Lu Wang,Haodan Kuang,Muhammad Azam,Gang Cao
Chemical structural characterization of chemical compounds from hawthorn fruits and its thermal processed products was carried out in present study. By linking Global Natural Products Social (GNPS) Molecular Networking and MolNetEnhancer workflow, seventy-four chemical compounds in hawthorn fruits and its thermal processed products were tentatively identified. Three quercetagetin derivatives (quercetagetin-3- O -glucoside, quercetagetin-di-glucoside and its isomer), five quercetin or kaempferol derivatives (quercetin-acetylapiosyl-hexoside, quercetin-3- O -(6″-malonyl-hexoside), quercetin-3- O -(6″-malonyl-hexoside)-(1 → 2)- O -hexoside, quercetin-3- O -(6″-malonyl-hexoside)-(1 → 2)- O -deoxyhexoside, kaempferol-3- O -(6″-malonyl-hexoside)), six procyanidins including four (E)C-ethyl-procyanidins and two A-type procyanidins digallate, as well as 13 triterpenoids including ursolic aldehyde, triterpenoid glycosides, and triterpene acids were reported for the first time in hawthorn fruits. In addition, triterpenoids exhibited considerable thermal stability, while all of flavonoid glycosides, proanthocyanidins and 10 in 13 organic acids showed dramatic decrease after thermal processing.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2023
·Vol. 46
·期 11
·2300037
·
IF 3.1
Yue Xiong,Zhuhui Chen,Peng-Bo Duan,Ranran Ma,Gisèle Ineza Urujeni,E-Hu Liu,Deli Xiao
In the classical natural product extraction and separation process, it is tedious and requires large amounts of reagents and time. In this study, an efficient coaxial liquid centrifugal oil-water-oil triple-liquid-phase system with a simple structure and convenient operation was successfully constructed and used to extract flavonoids from Platycladi Cacumen. The results showed that the coaxial liquid centrifugal platform constructed in this study had good stability and 6 ml was the minimum volume of the middle phase for 1000 rpm to stabilize the system. Besides, it was easy to repeat the operation: the relative standard deviations of the extraction yields of flavonoids and sugar in six parallel operations were all less than 10%. Moreover, it was only one-tenth of the time required for this method as traditional liquid-liquid extraction while reducing the use of volatile organic reagents. Finally, the new method was more selective than the traditional method for the extraction of flavonoids. Therefore, this study provides a possibility for the coaxial liquid centrifugal platform to be used in multi-liquid phase systems to achieve the simultaneous extraction of different parts of natural products by different liquid phases. It is expected to provide a reliable reference for further expansion of small-scale experimental operations to industrial production.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Bioscience
·
2023
·
IF 5.2
Qianwei Ma,Yang Yu,Zhongkai Zhou,Lili Wang,Ruge Cao
To take better advantage of the soluble dietary fibers (SDF) of buckwheat bran, different treatments including extrusion, steam explosion, microwave, roasting , superheated steam, ultrasound and enzymolysis were applied to buckwheat bran, and the monosaccharide compositions, structural, physicochemical and biological properties of SDF were estimated. Except enzymolysis treatment, all the other treatments have significantly increased ( p < 0.05) the content of SDF in buckwheat bran. Compared to natural SDF, the SDF in treated buckwheat bran showed porous and wrinkled surface, lower crystallinity, increased thermal stability and better rheological and hydration properties. These treatments have significantly improved the glucose adsorption capacity, nitrite ion adsorption capacity, antioxidant and antibacterial properties of SDF of buckwheat bran, among which extrusion showed the best effect. The microstructure, molecular size, monosaccharide and bound phenolics composition of SDF in buckwheat bran were effectively modified by appropriate treatments, with preferable physicochemical and biological properties.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 16
·7566-7574
·
IF 3.3
Shengbiao Zheng,Tianna Liu,Nini Zhang,Liang Li,Yanli Zhu,Erhui Zhang,Jing Tang,Jiahao Guo
In this report, CoNi-bimetal metal–organic framework (CoNi-MOF) nanosheets with a three-dimensional (3D) flower-like hierarchical structure have been fabricated to modify a glassy carbon electrode and improve its efficiency for determination of quercetin. Scanning electron microscopy, X-ray photoelectron spectroscopy, N2 adsorption–desorption isotherms and impedance spectroscopy were used for the characterization of the CoNi-MOF. Under optimal electrochemical conditions, the anodic peak current measured around 0.44 V (vs. SCE) increased linearly in two linear ranges: 0.05 to 1.0 μM and 1.0–20 μM with a sensitivity of 13.21 μA μM−1 cm2 and 0.934 μA μM−1 cm2, respectively. The excellent electrochemical performance might be attributed to the hierarchical structure, large specific surface area and enhanced electrical conductivity. Finally, the analytical utility of the CoNi-MOF sensor was evaluated by detecting quercetin in human plasma samples.
✓ 已验证
产品关联
DOI
高影响因子
Antioxidants
·
2023
·Vol. 12
·期 3
·664
·
IF 7
Mei Han,Fengxian Yang,Kun Zhang,Jiyan Ni,Xia Zhao,Xuelin Chen,Zhennan Zhang,Hanlei Wang,Jing Lu,Yumei Zhang
Tectona grandisis a traditional Dai medicine plant belonging to the Lamiaceae family, which can be used to treat malaria, inflammation, diabetes, liver disease, bronchitis, tumors, cholelithiasis, jaundice, skin disease and as an anti-helminthic. To find more novel therapeutic agents contained in this medicinal plant, the antioxidant, anti-inflammatory and anti-diabetic activities ofT. grandismethanolic extract, fractions and compounds were evaluated. In this study, 26 compounds were isolated from the leaves and branches ofT. grandis. Their structures were identified based on extensive spectral experiments, including NMR, ESI-MS and comparison with published spectral data. Among them, compounds1–2,4–6,9–14and16–22were reported for the first time for this plant. The antioxidant activity screening results showed that compounds5,15and23had potent antioxidant capacities, with SC50values from 0.32 to 9.92 µmol/L, 0.92 to 1.10 mmol Trolox/L and 1.02 to 1.22 mmol Trolox/L for DPPH, ABTS and FRAP, respectively. In addition, their anti-inflammatory effects were investigated by releasing TNF-α, IL-1βand IL-6 through the use of mouse monocytic macrophages (RAW 264.7). Compounds1,13,18and23had the effects of reducing the expression of inflammatory factors. Compounds13and18were reported for the first time for their anti-inflammatory activities. Furthermore, the methanolic extract (ME), petroleum ether extract (PEE) and EtOAc extract (EAE) ofT. grandisshowed significant glucose uptake activities; compounds21and23significantly promoted glucose uptake of 3T3-L1 adipocytes at 40 µM. Meanwhile, compounds4,5and7showed significant inhibitory activities against α-glucosidase, with IC50values of 14.16 ± 0.34 µmol/L, 19.29 ± 0.26 µmol/L and 3.04 ± 0.08 µmol/L, respectively. Compounds4and5were reported for the first time for theirα-glucosidase inhibitory activities. Our investigation explored the possible therapeutic material basis ofT. grandisto prevent oxidative stress and related diseases, especially inflammation and diabetes.Keywords:Tectona grandis;chemical composition;antioxidant activity;anti-inflammatory activity;α-glucosidase;glucose uptake
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Surfaces and Interfaces
·
2023
·
IF 6.2
Yulin Xu,Zhiqiang Xu,Congcong Chen,Weihao Ye,Baoyan Guo,Jiemin Qiu,Jianle Zhuang,Chaofan Hu,Bingfu Lei,Guangqi Hu,Yingliang Liu
In this paper, a kind of novel fully UV absorbing carbon dots (R-CDs) were prepared as UV absorbers by a one-step hydrothermal method using natural renewable rutin as raw material. R-CDs can achieve multifunctional applications under acid-base amphoteric conditions. Under acidic conditions, R-CDs have high absorption efficiency (over 98%) in the whole ultraviolet region (200–400 nm) which have wider UV absorption range than commercial water-soluble organic UV absorbers (BP-4) and are almost completely transmitted in the visible light region. The UV absorption mechanism of R-CDs be investigated to the UV absorption systems of degradable cellulose coating (CMC) and the R-CDs@CMC coating was applied to prevent UV leakage of the 395UV chip. Under alkaline conditions, R-CDs remain fully UV absorbing and good absorption stability, but BP-4 loses its function as a UV absorber. Finally, R-CDs was applied to the UV absorption and anti-blue light systems of PU . The R-CDs@PU are more effective than commercially available anti-blue light lenses. At present, the preparation process of R-CDs is simple and rutin is a natural renewable energy source. So, R-CDs have the potential to become a new generation of water-soluble UV absorbers and be applied to prevent blue light.
✓ 已验证
产品关联
DOI
高影响因子
Antioxidants
·
2023
·Vol. 12
·期 3
·552
·
IF 7
Abid Naeem,Chengqun Yu,Zhenzhong Zang,Weifeng Zhu,Xuezhen Deng,Yongmei Guan
Oxidants play a significant role in causing oxidative stress in the body, which contributes to the development of diseases. Rutin—a powerful antioxidant—may be useful in the prevention and treatment of various diseases by scavenging oxidants and reducing oxidative stress. However, low solubility and oral bioavailability have restricted its use. Due to the hydrophobic nature of rutin, it cannot be easily loaded inside hydrogels. Therefore, first rutin inclusion complexes (RIC) with hydroxypropyl-β-cyclodextrin (HP-βCD) were prepared to improve its solubility, followed by incorporation into xanthan gum-based (hydroxypropyl methylcellulose-grafted-2-acrylamido -2-methyl-1-propane sulfonic acid) hydrogels for controlled drug release in order to improve the bioavailability. Rutin inclusion complexes and hydrogels were validated by FTIR, XRD, SEM, TGA, and DSC. The highest swelling ratio and drug release occurred at pH 1.2 (28% swelling ratio and 70% drug release) versus pH 7.4 (22% swelling ratio, 65% drug release) after 48 h. Hydrogels showed high porosity (94%) and biodegradation (9% in 1 week in phosphate buffer saline). Moreover, in vitro antioxidative and antibacterial studies (Staphylococcus aureus,Pseudomonas aeruginosa, andEscherichia coli) confirmed the antioxidative and antibacterial potential of the developed hydrogels.Keywords:hydrogels;flavonoids;anti-oxidants;inclusion complexes;oral formulations
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nutrients
·
2023
·Vol. 15
·期 5
·1078
·
IF 5.9
Shengxiang Yi,Gaowei Zhang,Mingyan Liu,Wenjie Yu,Guohua Cheng,Liping Luo,Fangjian Ning
Citrus honey (CH) is rich in nutrients that have a wide variety of biological functions, such as antibacterial, anti–inflammatory, and antioxidant activities, and which demonstrate therapeutic properties, such as anti–cancer and wound–healing abilities. However, the effects of CH on alcohol–related liver disease (ALD) and the intestinal microbiota remain unknown. This study aimed to determine the alleviating effects of CH on ALD and its regulatory effects on the gut microbiota in mice. In total, 26 metabolites were identified and quantified in CH, and the results suggested that the primary metabolites were abscisic acid, 3,4–dimethoxycinnamic acid, rutin, and two markers of CH, hesperetin and hesperidin. CH lowered the levels of aspartate aminotransferase, glutamate aminotransferase, and alcohol–induced hepatic edema. CH could promote the proliferation of Bacteroidetes while reducing the abundance of Firmicutes. Additionally, CH also showed some inhibitory effects on the growth of Campylobacterota andTuricibacter. CH enhanced the secretion of short–chain fatty acids (SCFAs), such as acetic acid, propionic acid, butyric acid, and valeric acid. Given its alleviating functions in liver tissue damage and its regulatory effects on the gut microbiota and SCFAs, CH could be a promising candidate for the therapeutic treatment of ALD.Keywords:citrus honey;gut microbiota;alcohol–related liver disease;short–chain fatty acids
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）