MICROCHIMICA ACTA
·
2017
·Vol. 184
·期 9
·3487-3496
·
IF 4.58
Sun Duanping,Lu Jing,Wang Xiangyan,Zhang Yuanqing,Chen Zuanguang
The authors describe a method for the detection and determination of human liver cancer cells in blood. The cytosensing system consists of a microfabricated chip-based electrochemical aptasensor that contains multifunctional hybrid electrochemical nanoprobes and an indium tin oxide (ITO) electrode array interface functionalized with cell-targeting aptamer and gold nanoparticles (AuNPs). The thiolated cell targeting aptamer (referred to as TLS11a) was immobilized on the ITO electrode/AuNPs for specific adhesion of hepatocellular carcinoma cells (HepG2). The hybrid nanoprobe system consists of hydroquinone (HQ) as an electrochemical probe, horseradish peroxidase (HRP), and an aptamer/hemin/G-quadruplex aggregate that was immobilized on gold/palladium-functionalized ZnO nanorods (ZnO@Au-Pd). The nanoprobes are capable of amplifying the voltammetric signal and capturing the target cells. Best operated at around −90 mV (vs Ag/AgCl), the electrode has a linear response that covers the 10^2 to 10^7 HepG2 cells per mL concentration range, with a 10 cell per mL detection limit. Captured cells may be released from the electrode via electrochemical desorption to break the Au-S bonds.
Schematic of an indium tin oxide (ITO) electrode array-based electrochemical aptamer cytosensor for the specific capture, sensitive detection and controlled release of HepG2 cancer cells. AuNP: gold nanoparticle; HQ: hydroquinone; HRP: horseradish peroxidase.
研究领域:
生物传感器
·
电化学
·
癌症诊断
·
纳米技术
·
分子生物学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Yang Mi,Anqiang Jiang,Lei Kong,Jun Wang,Heng Guo,Sheng-Nian Luo
I–III–VI ternary quantum dots (QDs) have emerged as favorable alternatives to the toxic II–VI QDs for optoelectronic and biological applications. However, their use as optical gain media for microlasers is still limited by a low fluorescence efficiency. Here, we demonstrate amplified spontaneous emission (ASE) and lasing from colloidal QDs of Zn-processed AgIn5S8 (AIS) for the first time. The passivation treatment on the AIS QDs yields a 3.4-fold enhancement of fluorescence quantum efficiency and a 30% increase in the two-photon absorption cross section. ASE is achieved from the AIS/ZnS core/shell QD films under both one- and two-photon pumping with a threshold fluence of ∼84.5 μJ/cm2 and 3.1 mJ/cm2, respectively. These thresholds are comparable to the best optical gain performance of Cd based-QDs reported in the literature. Moreover, we demonstrate a facile whispering-gallery-mode microlaser of the core/shell QDs with a lasing threshold of ∼233 μJ/cm2. The passivated AIS QDs can be promising optical gain media for photonic applications.
研究领域:
量子点
·
光电子学
·
光子学
·
材料科学
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纳米技术
·
激光物理
✓ 已验证
DOI
高影响因子
Journal of Physical Chemistry C
·
2021
·
IF 4.126
Lixian Tian,Xianneng Song,Xi Yu,Wenping Hu
Facile modulation of the rectification behavior of a molecular junction device was achieved by humidity and alkali metal ions using a series of carboxylic acid-terminated self-assembled monolayers (COOH SAMs) on gold and eutectic gallium-indium alloy top contact (EGaIn). The rectification ratio (RR) increased significantly as the humidity (ranging from 1 to 39%) increases for an n-mercaptoalkanoic acid (HSCnO2H, n = 11, 12, 14, 16) SAM device. Meanwhile, K+/Na+, as the counterion of COO– in the same element group with H+, enhanced the RR of the SAM device as well. By the detailed study of the rectifying current–voltage (I–V) response using a theoretical model based on single-level tunneling, we found that the modulated rectification behavior of SAMs was attributed to the change in the coupling strength of the carboxylic group with the EGaIn electrode and the asymmetry factor of the junction in the presence of water and K+/Na+. Our study here suggested that the delicate electronic structure change at the molecule–(GaOx)GaIn interface played the most significant role in the modulation of the rectification performance of the SAM device. The molecule–(GaOx)GaIn interface thus offered a great research opportunity to achieve the desired function of SAM-GaIn-based molecular devices.
研究领域:
纳米技术
·
材料科学
·
电化学
·
表面化学
·
分子电子学
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2014
·Vol. 6
·期 23
·9228-9233
·
IF 1.938
Fen-fang Deng,Cong Ding,Yu Wang,Wen-ting Li,Li-li Liu,He Li
Samarium doped cerium dioxide (CSO) nanostructures possessing a shell-like morphology were synthesised by a simple hydrothermal method. A novel nanocomposite membrane, comprising of CSO nanostructures, chitosan (CH) and a room temperature ionic liquid (RTIL) was deposited onto an indium-tin oxide (ITO) electrode for developing a DNA biosensor related to the breast cancer gene. The properties of the CSO and nano-composite membrane were studied by thermogravimetry (TG), X-ray diffraction (XRD), energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The hybridization capacity of the DNA biosensor was studied by differential pulse voltammetry (DPV) using [Fe(CN)6]3−/4− as an indicator. Under optimal conditions, the fabricated DNA biosensor could quantify a wide range of target DNA concentrations over the range of 1 × 10−13 to 1 × 10−6 M with good linearity (R = 0.9981) and a low detection limit of 1.56 × 10−14 M (3σ). Results showed that the fabricated shell-like CSO nanostructures and RTIL could enhance the electrical conductivity synergistically, which has great potential application in sensitive electrochemical biosensors.
研究领域:
材料科学
·
生物化学
·
电化学
·
癌症诊断
·
纳米技术
✓ 已验证
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2013
·
IF 5.437
Bing Sun,Fengmin Qiao,Lijian Chen,Zhen Zhao,Huanshun Yin,Shiyun Ai
A universal and effective photoelectrochemical (PEC) immunosensing device was fabricated on an indium tin oxide (ITO) electrode for sensitive and specific detection of subgroup J of avian leukosis virus (ALVs-J) based on a signal-on strategy. Bismuth sulfide (Bi 2 S 3 ) nanorods , with good morphology , high crystallinity and differentiated PEC properties, were selected as the photoelectrochemical species and synthesized by a facile hydrothermal method . On the basis of alkaline phosphatase catalytic chemistry to in situ produce ascorbic acid for electron donating, an enhanced photocurrent was obtained. Due to the dependence of the photocurrent signal on the concentration of generated electron donor , an exquisite immunosandwich protocol was successfully constructed for PEC detection of ALVs-J with a linear range from 10 2.14 to 10 3.65 TCID 50 /mL. The detection limit was 10 2.08 TCID 50 /mL ( S / N =3), and high stability and specificity were obtained. The strategy provides a fast and sensitive method for ALVs-J analysis and opens a general format for future development of PEC immunoanalysis.
研究领域:
病毒学
·
光电化学
·
免疫学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
Frontiers in Nutrition
·
2022
·
IF 6.59
Yang Luoxing,Zhang Tongtong,Zhou Huaxu,Yan Fei,Liu Yan
Vertically ordered mesoporous silica film (VMSF) with uniform mesoporous channels perpendicular to electrode substrate has a wide range of applications in direct electroanalysis of complex samples. However, the detection of nucleic acid bases is difficult to realize at the commonly used VMSF-modified indium tin oxide (VMSF/ITO) electrode due to the high overpotentials of underlying ITO for many small organic molecules. In this work, we demonstrated an electrochemical method for the sensitive detection of guanine (G) by integration of VMSF/ITO and tris(2,2′-bipyridine) ruthenium (II) [Ru(bpy)32+] redox mediator. Ru(bpy)32+ electrostatically accumulated by VMSF is able to act as an electron shuttle between G and underlying ITO surface, showing electrocatalytic oxidation of G and enabling the quantitative determination of G with a limit of detection (LOD) of 0.058 μM and a limit of quantitation (LOQ) of 0.2 μM. Electrochemical detection performance for G could be regulated by changing the pH of the supporting electrolyte and the content of Ru(bpy)32+, achieving a wide dynamic linear range from 0.2 to 10 μM (R2 = 0.999), 2 to 100 μM (R2 = 0.999), and 10 to 500 μM (R2 = 0.998). Furthermore, owing to the good anti-fouling and anti-interference ability of VMSF, this simply sensing strategy can be applied to the direct and rapid detection of G in beer samples, and the detection of ganciclovir (G analog) content in ganciclovir eye drops.
研究领域:
分析化学
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纳米技术
·
电化学
·
生物传感器
·
药物分析
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2022
·
IF 4.598
Dongyue Feng,Zhijie Shang,Pan Xu,Haoyu Yue,Xinxue Li
The anode materials play a key role in the electrochemical oxidation process. In this work, a new type of Ti/Sn-SbO x /α-PbO 2 /La-In-β-PbO 2 electrode has been prepared through electrodeposition and applied to the degradation of high concentration aqueous solution of hydrolyzed polyacrylamide (HPAM). Scanning electron microscopy (SEM), X-ray diffraction (XRD), and Energy-dispersive spectroscopy (EDS) were employed to characterize the surface morphological and structural properties of the electrodes, which indicated that the La-In-PbO 2 electrode had smaller grain size, denser surface and larger active surface area compared with undoped and single-doped PbO 2 electrode. Cyclic voltammetry (CV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS) were also utilized to investigate the electrochemical performance of electrodes. The results showed that the La-In-PbO 2 electrode exhibited higher oxidation peak current, oxygen evolution potential (2.22 V) and lower charge transfer resistance. The La-In-PbO 2 electrodes were used as anode to degrade HPAM solution under different conditions. The results revealed that the viscosity reduction rate of HPAM reached to 97.63 % after 60 min under the condition of electrolyte concentration, initial concentration of HPAM, initial pH and current density were 0.05 M, 3 g·L −1 , 7 and 20 mA·cm −2 , respectively. The kinetic behavior of HPAM degradation was analyzed by the viscosity reduction experiment. The intermediates in the electrochemical oxidation process were identified by GC–MS and the possible degradation mechanism of HPAM was explored by UV–visible absorption spectra and the Fourier Transform Infrared (FT-IR) spectra.
研究领域:
环境工程
·
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Zhaoyang Wang,Yinshan Zhang,Yanhua Shi,Zhinmin Dong,Yuanping Jiang,Qian Liu,Zifan Li,Yuhui Liu,Xiaohong Cao,Yingcai Wang,Zhibin Zhang,Yunhai Liu
The main purpose of this paper is to study the extraction and separation of key fragment elements based on the electrolytic refining process of spent fuel dry reprocessing. Firstly, the electrochemical mechanisms of Er(III) and Yb(III) in LiCl-KCl molten salts were investigated on W and In film electrodes with applied cyclic voltammetry (CV), square wave voltammetry (SWV) and open circuit potential (OCP) at 773 K. The results indicated that the reduction behaviour of In(III) and Yb(III) ions were a two-step transfer process and Er(III) ions was a one-step transfer process. Then, the kinetic parameters in electrochemical processes were calculated on an In electrode with different temperatures. The OCP approach was used to determine the equilibrium potential of Er(III)/Er(0) in the temperature range of 773 K∼848 K, and thermodynamic parameters of the In 3 Er alloy were provided. Based on electrochemical behaviour results, the electrochemical extraction of Er(III) and Yb(III) from LiCl-KCl-ErCl 3 molten salts and LiCl-KCl-YbCl 3 molten salts at liquid In electrodes was performed by constant potential and constant current electrolysis, respectively. The electrolysis products were determined by X-ray diffraction (XRD), scanning electron microscopy and energy dispersive spectrometry (SEM-EDS), the primary intermetallic compounds generated in the alloys were In 3 Er and In 3 Yb. The average extraction rates for Er(III) and Yb(III) were 94.70% and 96.54%, respectively, according to inductively coupled plasma atomic emission spectroscopy (ICP-AES) analysis. Er(III) and Yb(III) were selectively extracted and separated from LiCl-KCl-ErCl 3 -YbCl 3 molten salts by potentiostatic control on the basis of the previously studied Lns (Er and Yb) extraction on In electrodes. The separation rate of Er(III) and Yb(III) by electrochemical selective deposition was 94.21%.
研究领域:
电化学
·
材料科学
·
核工程
·
热力学
·
动力学
✓ 已验证
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2024
·
IF 8.1
Xueting Yang,Dezhan Ye,Chenyi Wang,Yazhou Chen,Xiancai Jiang,Yingcheng Yang,Zengjin Liu
The emerging approach of in-situ polymerization of solid polymer electrolytes based on 1,3-dioxolane (DOL) possesses the advantage of low interfacial impedance and relatively high Coulombic efficiency. However, the DOL monomer conversion (C%) under Lewis acid catalysts needs to be further improved, besides their alloying ability with lithium metal to generate protective interfacial layer has been ignored. Here, the above two aims are simultaneously achieved by Indium Trifluoride (InF 3 ) catalyst. It is demonstrated that the highest C% is up to 94% with 15 mg of InF 3 in the 1 mL electrolyte (1 M LiTFSI/DOL). The optimized ionic conductivity and lithium-ion transfer number are 8.9 × 10 −5 S/cm (30 °C) and 0.42, respectively. The stable interface between poly-DOL and lithium metal anode could be proved by the stable over-potential (156mv, 900 h) at current density of 2.0 mA cm −2 . X-ray diffraction results confirm the presence of In and In–Li alloy peaks. After 300 cycles at 1C, the assembled Li/PDI 15 /LiFePO 4 cells deliver a 125.2mAh/g, 90% capacity retention and Coulombic efficiency of 99.75%, respectively. This innovative and facile strategy of dual functional InF 3 on the in-situ polymerization of DOL and solid electrolyte interphase formation provides new ideas for design poly-DOL based solid polymer electrolytes.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
Energy Material Advances
·
2026
·
IF 17.4
Wenying Wang,Xiaojie Ji,Lin Bo,Wenying Zhou,Xingshuo Liu,Zheng Zhang,Degang Zhao
AgInSe2 has been regarded as a highly promising candidate for mid-temperature thermoelectricapplications, primarily attributed to its intrinsic low lattice thermal conductivity and superiorenvironmental friendliness. To enhance its practical applicability and address the critical limitationsof inherently low electrical conductivity and suboptimal power factor, this study adopted the rapidmicrowave melting to synthesis the material, and integrated the dual optimization strategies of Fedoping and carbon nanotubes (CNTs) compositing to synergistically regulate the thermoelectrictransport properties. Systematic investigations revealed that Fe doping effectively optimized thecarrier concentration of the material to 2.96×1019 cm–3, laying a foundational framework for furtheroptimization. The incorporation of CNTs not only furnished high mobility pathways for electrontransport but also introduced more interface phonon scattering centers, synergistically decreasingthermal conductivity while enhancing electrical conductivity. Notably, the AgIn0.99Fe0.01Se2-0.6wt% CNTs sample achieved a peak thermoelectric figure of merit (ZT) of ~ 0.55 at 780 K,representing a 1.5-times enhancement compared to the pristine material. Additionally, the Vickershardness of the optimized composite was improved by 32%, realizing the concurrent optimizationof both thermoelectric transport properties and mechanical performance. By orchestrating a dual-optimization paradigm, this investigation elucidates the microscopic mechanisms governingthermoelectric transport properties enhancement in intrinsically low-carrier AgInSe2, therebyfurnishing a transferable roadmap for elevating environmentally benign energy-harvestingtechnologies toward practical deployment.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Energy Materials
·
2026
·
IF 5.5
Zhongshuo Li,Tingting Zhang,Zhangheng Lai,Yutao Mo,Zhengmao Luo,Ning Qi,Zhiquan Chen
SnTe is widely recognized as a promising alternative to environmentally harmful PbTe for thermoelectric applications at moderate and high temperatures. Nevertheless, due to the ultrahigh hole concentration as well as lattice thermal conductivity, the thermoelectric performance of pure SnTe is greatly constrained. In our work, a novel strategy was put forward to optimize the relatively poor thermoelectric performance of SnTe by simultaneously incorporating In2Se3 and Cd. The Seebeck coefficient was apparently improved through the whole temperature range originating from the introduction of resonant energy levels achieved by In doping, while lattice thermal conductivity was decreased to a relatively low level of ∼0.49 W m–1 K–1 at 873 K, owing to a decrease in sound velocity and strong scattering on phonon caused by nanopores and dislocations after doping. Profiting from the synergistic optimization thermoelectric performance strategies, a peak zT of 1.32 at 873 K was achieved in Sn0.96Cd0.04Te+1%In2Se3, which represents a remarkable 89% increase over pristine SnTe. And an average zT of 0.66 from 303 to 873 K was also obtained. Our work provides a new strategy for multifunctional synergistic modulation of the thermoelectric properties of SnTe-based materials.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Tao Lin,Jiangtao Guo,Qingju Liu,Zhigang Chen,Yong Zhang,Wen Yang,Jun Wang,Peizhi Yang,Liangfei Duan
The non-contact energy harvesting technologies are critical for microelectronic devices, especially in special scenarios such as enclosed spaces or extreme environments. Room-temperature liquid metals (LM), possessing both metallic and fluidic elastic properties, have emerged as the preferred materials for high-density integration, morphological reconfigurability, high performance stability, and stringent biocompatibility standards. Herein, we present a flexible ultrasonic energy harvesting and direct current (DC) generation system based on LM. This system relies on an interface between eutectic gallium‑indium‑tin alloy (eGaInSn) LM and silicon dioxide in the system. The device leverages the inherent properties of LM, utilizing electromechanical coupling technologies to facilitate intelligent perception, collection, and transformation of non-contact ultrasonic energy stimulation. This innovative approach culminates in a high-voltage DC output and facilitates dynamic DC power amplification without rectification circuits. The device outputs a notable voltage of up to 2.5 kV under a load in a double electrode configuration, while a single electrode design attains an exceptional open-circuit voltage ( V oc ) as high as 6 kV. This work expands the basic understanding of LM, electromechanical conversion, and force-electric coupling, leading to straightforward practices for ultrasonic energy harvesting and high-performance DC output. It also offers promising potential for future self-powered sensing systems, human-computer interfaces, arrayed broadcast group high-efficiency charging, and wearable energy solutions.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）