RSC Advances
·
2017
·Vol. 7
·期 45
·28476-28482
·
IF 3.108
Xiuqin Cai,Yunhua Xu,Rong Yang,Hui Yang
A novel calix[4]arene-based tetracholesteryl derivative was synthesized, and its gelation behaviours in 30 organic solvents were studied. It showed that 1 gelled long chain alkane, some of alcohol, kerosene, ethyl acetate benzene and toluene. Interestingly the gel of 1/kerosene possessed special property, which was that the mixture solution of the compound 1/kerosene heating for a while was put on the flat contact heater and formed a gel film at 25 °C and 65 °C. Unlike ordinary film, gel film had higher strength and toughness at 65 °C, by contrast other was fragile and broken easily at 25 °C, this phenomenon was few reported before. In order to explore the phenomenon, the mechanism of the gel of 1/kerosene was discussed by Scanning Electron Microscope (SEM), High Nuclear Magnetic Resonance (H NMR), Fourier Transform Infrared Spectrometer (IR) and micro-rheology. SEM revealed that the xerogel of 1/kerosene assembled network through some long and thick fibers at 65 °C, with concentration reducing fibers become thin and its networks were clearly observed. In contrast the morphology of xerogel was porous at low concentration and was a bulk at high temperature system. According to EI data in micro-rheology, the gelation process could be divided into three stages at 65 °C and they could be that some cholesterol segments in the gelator interacting with each other formed some small aggregation in the first stage, and other cholesterol section of the gelator sufficiently were cross-linked with time and assembled into large assembly in the second plateau. In the final moment the large assembly build gel network and the system of gel tended to stable. But there are two stages at low temperature and could be some cholesterol segments that didn't take part in assembly, which may be the cause that the performance of gel was fragile.
研究领域:
材料科学
·
化学
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产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2018
·
IF 6.042
Jian Sun,Jiahui Zhao,Xingfu Bao,Qifeng Wang,Xiurong Yang
Diethanolamine (DEA) has been extensively utilized as an alkaline buffer in current assays of alkaline phosphatase (ALP) activity in the past decades. While playing the role of a buffer, the chemical reactivity of DEA has been widely ignored in such assays. Herein, we report an interesting chromogenic interaction between DEA and 4-aminophenol (AP) in the presence of H2O for the first time, which inspires us to develop a novel DEA-participated ALP activity assay by using 4-aminophenyl phosphate (APP) as a substrate. This APP/DEA-based colorimetric approach has been proved to be comparable and even superior to the conventional p-nitrophenyl phosphate (pNPP)-based one, especially in the low ALP activity region, due to its higher sensitivity. The clear response mechanism and excellent sensing performance ensure that it can be further applied to determining ALP activity in real biological samples, screening potential ALP inhibitors in vitro, establishing ALP-enabled ELISA, and even fluorophore-assisted fluorescent ALP activity assay. It is demonstrated that this strategy not only possesses a good feasibility, but also exhibits a promising outlook for a series of ALP-related and -extended detections.
研究领域:
生物化学
·
医学检测
·
酶学研究
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF HETEROCYCLIC CHEMISTRY
·
2022
·Vol. 60
·期 1
·145-155
·
IF 2.035
Abdalla Khallaf,Ping Wang,Shuping Zhuo,Hongjun Zhu,Hui Liu
The insecticidal activity of 1,3,4-oxadiazole-ring containing pyridylpyrazole-4-carboxamides against diamondback ( Plutella xylostella ) and noctuid ( Spodoptera frugiperda ) moths were evaluated. Only substitutions on the 1,3,4-oxadiazole moiety dictated bioreactivity, with 8q2 m -CF 3 Ph being the most effective against Plutella xylostella, showing 80%–93% mortality at a concentration of 0.5–500 μg ml −1 while the others remained inactive or less active (highest mortality being 63%). The larvicidal activity against Spodoptera frugiperda was inferior compared with that of Plutella xylostella , with the highest mortality being 33%. A crystal of 8q5 was obtained and analyzed, revealing the effects of intramolecular H-bonds and intermolecular π π interactions.
研究领域:
昆虫学
·
有机化学
·
农药科学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Xiaowen Wang,Dameng Gao,Xiao Liu,Xingyue He,Jian-Gong Ma,Peng Cheng
4-Nitrophenol (4-NP) is a common stuff involved in industrial production as well as a toxic pollutant which poses a threat to the environment and human health if not handled properly. Here, we have designed and synthesized two new metal-organic frameworks (MOFs), namely Ce-MOF-1 and Ce-MOF-2 with both fluorescent and electrochemical activities, which exhibite dual-mode sensing of 4-NP. The fluorescence emission spectra at 366 nm of both Ce-MOF-1 and Ce-MOF-2 displayed a significant turn-off signal affected by the competitive absorption and photoelectron transfer of 4-NP with the detection limits of 1.25 and 0.78 μM, respectively. Simutanously, in electrochemical sensing, 4-NP is irreversibly reduced to 4-hydroxylamine phenol under the catalysis of Ce-MOFs coating on electrode, which exhibit higher accuracy than fluorescence with detection limits of 0.36 and 0.41 μM, respectively, for the quantitatively sensing of 4-NP. Due to their complementary immunity to interference in electrochemical and fluorescence methods for 4-NP detection, Ce-MOFs exhibit more accurate 4-NP detection ability compared to other sensors. Finallly, both Ce-MOFs demonstrate excellent stability, reproducibility and selectivity in dual-mode sensing of 4-NP in tap water, that provides superior adaptability, reliability and accuracy compared to the traditional single-mode sensing method.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
·
2023
·
IF 1.7
Bo Zhou,Lu-Lu Liu,Wang-Yu Zhao,Li-Juan Han,Ai-Juan Li,Chun Zhao,Wen-Jun Wu,Ji-Wen Zhang
A series of 4-(propargyloxy) benzenesulfonamide derivatives with different substituents on the benzene ring were synthesized and evaluated for their insecticidal activity. Some of the compounds showed good insecticidal activity against Mythimna separata, and the LC50 value of the most active compound B2.5 was 0.235 mg/ml. Ultrastructural changes in the midgut epithelial cells of Mythimna separata were observed using transmission electron microscopy, and severe structural damage was found in microvilli, mitochondria and rough endoplasmic reticulum. It indicates that the possible site of action of these benzenesulfonamides is the cytoplasmic membrane and endomembrane system of the midgut epithelial cells. The above provides a basis for the development of novel insecticidal active compounds with a novel mechanism of action.
研究领域:
农药化学
·
昆虫生理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2013
·
IF 2.206
Yan-Chao Qu,Zhi Wang,Qiang Lu,Ying Zhang
4-Vinylphenol is an important chemical that can be used as the monomer for the production of poly(4-vinylphenol) (PVPh). Currently, 4-vinylphenol was prepared by the dehydrogenation of 4-ethylphenol over chromia/alumina catalyst at 600 °C. In this study, a low-cost process involving low-temperature fast pyrolysis of biomass without any catalyst was developed to selectively produce 4-vinylphenol. Pyrolysis gas chromatography/mass spectrometry (Py–GC/MS) was used for the fast pyrolysis of bagasse, cornstalk, bamboo, rice husk, rice straw, cotton straw, and poplar wood to investigate the effects of different materials on the selectivity of 4-vinylphenol. It was found that some of the herbaceous materials, such as bagasse, cornstalk, and bamboo, were suitable for the production of 4-vinylphenol, whereas woody materials were not applicable. The effects of temperature on 4-vinylphenol production were also investigated. 4-Vinylphenol contents of up to 7 and 20 wt % were achieved at 300 °C from bagasse and bagasse EMAL, respectively. For the first time, 4-vinylphenol was separated from the pyrolysis oil obtained by the fast pyrolysis of bagasse using a benchtop unit, and its structure was confirmed by various methods. Additionally, it was verified that 4-vinylphenol could be produced from compounds with a β-5 linkage, and a possible mechanism for the generation of 4-vinylphenol from a lignin model compound with a β-5 linkage is proposed.
研究领域:
生物化学
·
可再生能源
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2014
·Vol. 22
·期 5
·3856-3864
·
IF 2.757
Yang Xingjian,Lu Guining,Wang Rui,Guo Chuling,Zhang Hongliang,Dang Zhi
This paper is focused on the selection of cosolvents in the remediation of contaminated soils. The aim of this study was to investigate the combined effects of Triton X-100 (TX-100) and different cosolvents on the solubilization behavior of 4,4′-dibromodiphenyl ether (BDE-15) and the washing of BDE-15 from a contaminated soil. 1 H NMR spectroscopies were used to elucidate the interactions among TX-100, cosolvents, and BDE-15 in aqueous micellar solution. Results showed that the solubility of BDE-15 was enhanced by the observed synergism among TX-100, BDE-15, and cosolvents, and the TX-100/dimethyl sulfoxide (DMSO) system exhibited the best performance in the solubilization of BDE-15. Similar synergism was further evidenced in the washing of BDE-15 from a contaminated soil. With 10 % ( v / v ) DMSO and 6.4 mM TX-100 solution added, considerable synergistic effect was achieved in TX-100/DMSO system, leading to the highest removal efficiency (92.9 %) of BDE-15 from the soil, relative to that of 67.3 % with TX-100 alone at the same concentration.
研究领域:
环境科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2013
·Vol. 180
·期 11
·1051-1057
·
IF 3.434
Wang Ai-Jun,Guo Han,Zhang Ming,Zhou Dan-Ling,Wang Rui-Zhi,Feng Jiu-Ju
We have developed a simple, sensitive and selective colorimetric method for the detection of cadmium(II) (Cd 2+ ) using gold nanoparticles modified with 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole. Organic solvents or additives are not required. It is found that Cd 2+ induces the aggregation of the modified Au-NPs via chelation, leading to a color change from red to blue. This change can be seen with bare eyes, and monitored by UV–vis spectroscopy, transmission electron microscopy and dynamic light scattering. The detection limit is 30 nM (at a signal-to-noise ratio of 3). The new approach was successfully applied to the detection of Cd 2+ in spiked samples of tap water and lake water, and the results agree well with those obtained by flame atomic absorption spectroscopy.
A simple, sensitive and selective colorimetric method was developed for the detection of Cd 2+ , where 4-amino-3-hydrazino-5-mercapto-1,2,4-triazol (AHMT) modified gold nanoparticles (AuNPs) were used as optical probes. The presence of Cd 2+ induced the aggregation of the AHMT-AuNPs through the chelation process. This approach was successfully applied for the detection of Cd 2+ in spiked samples of tap water and lake water.
研究领域:
分析化学
·
环境科学
·
纳米技术
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Qing Zheng,Nannan Wu,Ruijuan Qu,Gadah Albasher,Wanming Cao,Beibei Li,Nouf Alsultan,Zunyao Wang
4- tert -butylphenol (4-tBP) is a phenolic endocrine disrupting chemical that has attracted great attention due to its wide occurrence, environmental persistence, and possible toxic effects. In this study, we systematically investigated the transformation of 4-tBP in ferrate (VI) oxidation process. The second-order reaction rate constant ( k app ) of Fe(VI) with 4-tBP decreases with solution pH, and the k app value was determined as 295 M −1 ·s −1 at pH 8.0. The removal efficiency of 4-tBP was slightly decreased by Mg 2+ and HCO 3 – , while accelerated at varying degrees by the presence of Cu 2+ and humic acid. Product analysis revealed that 4-tBP was mainly transformed into hydroxylation products, benzene-ring cleavage products, dimers and higher polymerization products via oxygen atom transfer, ring-opening of the benzene ring and radical coupling reaction. Furthermore, initial reactions of 4-tBP were rationalized by theoretical analysis of atom partial charges, frontier electron densities, and spin densities. Nearly complete removal of 4-tBP (20 μM) was achieved after 5 min of reaction in both ultrapure water and natural waters, demonstrating the feasibility of this Fe(VI) oxidation method in treating phenols-contaminated waters.
研究领域:
环境科学
·
化学动力学
✓ 已验证
DOI
PubMed
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2019
·Vol. 38
·期 1
·53-62
·
IF 2.804
Chen Tao,Zhong Guo-Cheng,Zhang Yuan-Ting,Zhao Li-Ming,Qiu Yong-Jun
Novel bio-based and biodegradable block copolymers were synthesized by “click” reaction between poly(L-lactide) (PLLA) and polyamide 4 (PA4). Upon tuning the molar mass of PLLA block, the properties of copolymers and electrospun ultrafine fibers were investigated and compared with those of PLLA and PA4 blends. PLLA and PA4 were found incompatible and formed individual crystalline regions, along with reciprocal inhibition in crystallization. Electrospun fibers were highly hydrophobic, even if hydrophilic PA4 was the rich component. The crystallinity of either PLLA or PA4 decreased after electrospinning and PLLA-rich as-spun fibers were almost amorphous. Immersion tests proved that fibers of block copolymers were relatively homogeneous with micro-phase separation between PLLA and PA4. The fibrous structures of copolymers were different from those of the fibers electrospun from blends, for which sheath-core structure induced by macro-phase separation between homopolymers of PLLA and PA4 was confirmed by TEM, EDS, and XPS.
研究领域:
材料科学
·
生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2018
·Vol. 165
·期 11
·B491
·
IF 3.662
Junjuan Qian,Depeng Zhang,Lirong Liu,Yinhui Yi,Mwenze Nkulu Fiston,Odoom Jibrael Kingsford,Gangbing Zhu
As a novel nanomaterial after graphene, molybdenum disulfide (MoS2) has potential applications in electrochemical sensing and other fields, while the low electric conductivity of MoS2 limits its application significantly. In this paper, carbon spheres (CSs) wrapped with molybdenum disulfide (CSs@MoS2) novel nanostructure was successfully prepared via a green hydrothermal method and then used for firstly electrochemical sensing of 4-aminophenol (4-AP, one toxic pollutant). The morphology and structure of CSs@MoS2 were characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, Raman spectroscopy and electrochemical impedance spectroscopy. As an electrochemical sensor, CSs@MoS2 nanohybrids modified electrode exhibits excellent electrochemical sensing performance toward 4-AP analysis owing to the synergetic advantages of MoS2 and CSs. Under the optimized conditions, the detection limit of 4-AP obtained in this work is 3 nM and the linear range is 0.01–18.00 μM.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2015
·
IF 3.65
Li Qingcong,Pan Xiaoxia,Li Hongli,Yuan Minglong
A relatively high molecular weight of 4-arm star PELA was obtained by ring-opening polymerization of l -lactic acid O -carboxyanhydride with 4-arm-PEG in the presence of DMAP as an initiator. The results via 1 H NMR and 13 C NMR show that the end of the star PELA chain is a hydroxyl group and the central core is a PEG group. Rotavirus (strain SA11) was incorporated into 4-arm star PELA microspheres formulated by the water in oil in water emulsification solvent extraction method. The microspheres produced were spherical, and the mean diameter was 1.34 μm with a narrow size distribution. The drug release profile displayed a low burst release effect of 1.8% on the first day and a sustained release of antigen over 100 days. After the immunization of mice, the microsphere-entrapped RV elicited improved and long-lasting IgA and IgG antibody response in serum detected by ELISA in comparison to the free RV antigen. This study shows that 4-arm-PEG is an effective initiator for the ring-opening polymerization of Lac-OCA by DMAP as an initiator and that the resulting polymer is useful as a delivery system for the rotavirus vaccine .
研究领域:
生物材料学
·
疫苗学
·
药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）