JOURNAL OF MEMBRANE SCIENCE
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2026
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IF 8.8
Daojiang Zhu,Shuhong Zhao,Chen Yang,Zheng Liu,Yifan Li,Chang Huang,Yuan Xia,Tingting Xu,Xingya Li,Tongwen Xu
Mixed-matrix membranes (MMMs) incorporating covalent organic frameworks (COFs) offer a promising strategy to overcome the permeability-selectivity trade-off effect in conventional polymer membranes for ion separation. However, agglomeration of COF fillers often leads to structural defects and performance degradation in MMMs. Herein, we report in situ synthesized CA@COF MMMs by integrating fibrous COF (TpPaCOOH) with cellulose acetate (CA) at a low loading of 1.63 wt%, achieving hydrogen bond-enhanced interfacial compatibility and uniform filler dispersion. In the binary-ion system for Li + /Mg 2+ separation, despite this minimal COF content, the resulting CA@TpPaCOOH membrane exhibits 21-fold and 16-fold enhancements in Li + /Mg 2+ selectivity compared with pristine CA and COF membranes, respectively, reaching a selectivity of ∼51 and a Li + flux of ∼0.3 mol m -2 h -1 . Moreover, the CA@TpPaCOOH membranes demonstrate a scalability with consistent performance across batch-to-batch synthesis and retention of >83.2% selectivity in pilot-scale (900 cm 2 ) preparations. This highly reproducible, low-dosage strategy provides a transformative pathway for efficient lithium recovery from brine.
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高影响因子
JOURNAL OF POROUS MATERIALS
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2025
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IF 3.2
Feng Yulin,Xu Fen,Sun Lixian,Shao Qiwei,Xu Rudan,Chen Yue,Yu Chuyu,Du Maozhan,Xie Yingguang
The interfacial chemical bonding strategy has been proposed by utilizing the expanded graphite (EG) as substrate to overcome the inherent low conductivity of covalent organic frameworks (COFs) in supercapacitor in this work. A redox-active COF material grows in situ on the EG surface through a solvent-free synthesis method, successfully constructing a novel layered porous EG@COF composite. Analysis results of BET, XPS and resistivity of materials demonstrate that the EG@COF not only preserves the intrinsic high specific surface area of COFs, but also effectively reduces interfacial contact resistance via amidation reaction, significantly enhancing charge transfer efficiency. Electrochemical studies reveal that the optimized EG@COF-3 electrode has a high specific capacitance of 501 F g − 1 at 1 A g − 1 , with 92.3% capacity retention after 10,000 cycles, demonstrating a good cycling stability. Furthermore, the assembled EG@COF//AC asymmetric supercapacitor achieves an energy density of 16.4 Wh kg − 1 at a power density of 806.0 W kg − 1 . This work provides an effective solution to improve the conductivity of COF materials.
研究领域:
材料科学
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能源科学
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Journal of Materials Chemistry B
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2025
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IF 5.7
Donghan Shao,Xinyu Pei,Yuqin Ma,Sainan Liu,Wenliang Li,Leijiao Li,Ping’an Ma
Sonodynamic therapy (SDT) has emerged as an encouraging route in tumor treatment, due to its exceptional tissue penetration depth and favorable safety profile. Nevertheless, the clinical translation of conventional organic sonosensitizers is hindered by intrinsic limitations, including pronounced hydrophobicity, insufficient chemical stability, and low reactive oxygen species (ROS) production. In contrast, hollow covalent organic frameworks (HCOFs) exhibit exceptional cargo-loading capabilities, structural robustness, and biocompatibility, positioning them as ideal nanoplatforms for advanced therapeutic applications. Herein, we engineered a bowl-shaped HCOF architecture designed to amplify ultrasonic cavitation effects. This nanostructure was subsequently functionalized with the sonosensitizer (Hemin) and subjected to strategic metallization via metal ion incorporation, culminating in the development of a high-efficiency antitumor nanosystem (FeHHCA). FeHHCA can achieve dual-mode ROS generation, namely, sonodynamic synergistically generating 1O2 and being specifically activated by a tumor microenvironment (TME) to generate ˙OH through a Fenton-like reaction, achieving an 78.7% tumor inhibition rate in vivo. These findings offer innovative approaches and strategies for the design of hollow COFs and offer great potential for the application of SDT in cancer treatment.
研究领域:
生物医学工程
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肿瘤学
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纳米医学
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高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2025
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IF 4.7
Xiaochen Li,Xin Qin,Cong Yu,Lan Lin,Jinchao Cao,Qiang Chen,Shi-Peng Sun,Jingcai Chang,Xinbo Wang
Selective and efficient dehydrogenation of neat formic acid (FA) under controlled conditions, eg. light, is important yet scarce. Herein, an organic-metal heterostructurre of COF-Cu was constructed by incorporation of Cu 2+ with a covalent organic framework AQ-COF. COF-Cu showed a remarkable photocatalytic FA dehydrogenation activity, without any solvent or base additive. The optimal H 2 evolution rate reached 190 mmol·g −1 ·h −1 , surpassing most of the state-of-the-art catalyst. The significant performance enhancement of COF-Cu can be attributed to the effective charge transfer process occurring between AQ-COF and Cu 2+ . This study provides valuable insights for the design of efficient catalysts, crucial for advancing sustainable energy storage technologies.
研究领域:
材料科学
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能源化学
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催化反应
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JOURNAL OF MEMBRANE SCIENCE
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2025
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IF 9
Qianxi Yang,Bingqian Kang,Wenjing Han,Haoran Wang,Sinan Cheng,Junjie Liu,Hongwei Fan,Hong Meng
Covalent organic frameworks (COFs) membranes have shown huge potential in low-cost nanofiltration treatment of saline industrial wastewater with high permselectivity. However, their practical application is often limited by complicated preparation processes, particularly the extensive use of toxic solvents such as 1,4-dioxane and dichloromethane. Herein, we present a facile and environmentally-friendly strategy to synthesize high-quality COF membranes exclusively in aqueous system instead of any organic reagents. The procedure involves depositing water-synthesized TpPa-1 onto a porous substrate via vacuum filtration, followed by cross-linking with epichlorohydrin (ECH). This method significantly mitigates health and safety risks by eliminating the use of hazardous organic solvents throughout the entire process. The green metrics assessment further confirmed the environmental advantages of aqueous synthesis strategy. The resultant TpPa-1-ECH membrane exhibited an excellent nanofiltration performance for dye desalination. The separation factor of Congo red/NaCl can reach 139, while the permeation flux can reach 450 L m -2 h -1 MPa -1 . The overall performance not only far surpasses most polymeric membranes but is also comparable to other reported COF membranes prepared with toxic organic solvents.
研究领域:
材料科学
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环境工程
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膜技术
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可持续化学
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2025
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IF 9
Shi-Yuan Zhang,Fan-Xin Kong,Yi Wang,Jin-Fu Chen,Ai-Guo Zhou
Traditional nanofiltration (NF) membranes exhibit low rejection ratios for low-molecular-weight (LMW) or positively charged pharmaceuticals owing to broad pore size distributions and negatively charged surface. Covalent organic frameworks (COFs) are highly promising for membrane fabrication due to their tunable pore functionality and adjustable pore sizes. Herein, dual-charged COF membranes were fabricated via sodium dodecyl sulfate (SDS)-mediated interfacial polymerization (IP), followed by polyethyleneimine (PEI) crosslinking to improve the removal of LMW or positively charged pharmaceuticals. In the SDS-mediated IP process, the reduction of pore size from 0.387 ± 0.60 nm (COF 0-10 membrane fabricated without SDS) to 0.269 ± 0.54 nm (COF 0.25-10 membrane) led to a substantial improvement in Na 2 SO 4 rejection ratio from 43.9 % to 81.4 %. Furthermore, PEI crosslinking with residual free -CHO groups on the COF 0.25-10 membrane surface enhanced size sieving and electrostatic interactions while preserving membrane crystallinity. The optimized COF 0.25-10 -PEI 0.2-2.5 membrane with the pore size of 0.209 nm demonstrated exceptional rejection ratios (>87 %) for five representative pharmaceuticals with different properties. Among them, the optimized COF 0.25-10 -PEI 0.2-2.5 membrane showed superior rejection ratio of 92.6 % for the positively charged and LMW (129.16 Da) metformin. Compared to the pristine COF 0.25-10 membrane without PEI crosslinking, the resulting COF-PEI membranes demonstrated 3.8-6.5 folds improvement in pharmaceutical rejection, particularly for challenging LMW and positively charged pharmaceuticals, owing to the synergistic effects of size exclusion and electrostatic interactions. Furthermore, mechanistic study revealed that SDS in aqueous phase promoted faster and more uniform diffusion of TG Cl monomers, enhancing the crystallinity of the TpTG Cl -COF membranes and improving the pore uniformity, while PEI crosslinking further narrowed the pore size and obtained dual- charged COF layer. This study provides a new paradigm for designing charge-tunable and crystalline COF membranes for precision separation of LMW pharmaceuticals.
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ANALYTICA CHIMICA ACTA
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2025
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IF 6
Jiale Zhang,Qixuan Mu,Xinyue Li,Yifang Liao,Ruijun Li,Yibing Ji
Background Enzymes, with their broad chiral recognition capabilities, are promising but limited by stability issues. Covalent organic frameworks (COFs), with high surface area, porous structure, and biocompatibility, offer an ideal platform for enzyme immobilization. However, the non-matching between the large size of enzyme molecules and the pore size of COFs, along with conformational disturbances during the immobilization process, as well as the complex preparation, low efficiency, and poor stability of traditional enzyme-based chiral stationary phases (CSPs), hinders the application of highly chiral selectivity of enzyme in enatioseparation. Results A green synthesis strategy is introduced to overcome the limitations of conventional enzyme@COF synthesis, enabling the facile anchoring of pepsin onto TpPa-1 with small pores. The in-situ encapsulation approach facilitates high enzyme loading and excellent stability, which lead to the remarkable potential of Pepsin@TpPa-1 for enhanced chiral selectivity. Inspired by the in-situ concept, an innovative chromatographic column preparation technique is developed by growing Pepsin@TpPa-1 directly within capillaries, creating an capillary electrochromatography open-tube column (OT-CEC) with high-density chiral recognition sites, achieving efficient separation of diverse chiral drugs, including β-blockers, esterase inhibitors, and other types. The complex chiral recognition mechanism of pepsin is revealed at the molecular level, and the positive correlation between Pepsin@TpPa-1 activity and chiral selectivity is explored for offering theoretical support for designing high-performance chiral recognition platforms. Significance:This study represents the first application of enzyme-COF composites in CEC CSPs, overcoming challenges like low enzyme loading and instability. This enzyme-based CSP facilitated the extensive separation of chiral drugs. A novel insight is provided into the recognition mechanism, as well as the relationship between pepsin’s activity and its chiral selectivity. Furthermore, the highly stable chiral nanobiohybrid separation platform introduces a pioneering research paradigm for CSP development in OT-CEC.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
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IF 9
Jie Gao,Li-Bo Huang,Xianghao Meng,Lei Xia,Fan Yi,Zexuan He,Zeyu Pei,Changting Hong,Guo Wang,Yuhan Wang,Zhongyi Jiang
Nanofiltration holds significant potential for mitigating water scarcity, yet reconciling high selectivity with efficient mass transfer remains a critical challenge. MXene membranes enable precise molecular sieving through interlayer spacing, while covalent organic framework (COF) membranes leverage penetrating pores for rapid mass transfer. However, MXene membranes suffer from restricted permeability and structural instability, whereas COF membranes face limitations in achieving small-sized pores and compromising sieving efficiency. Herein, we fabricate a heterostructured MXene/COF membrane by synergistically manipulating interlayer spacing of MXene with penetrating pores of COF via sequential vacuum-assisted self-assembly. Matched surface hydrophilicity and electrostatic property between MXene and COF render robust interfacial adhesion. The optimal MXene/COF membrane exhibits a water permeance of 356.6 ± 24.1 L m −2 h −1 bar −1 and a CR rejection of 99.8 %, along with excellent operational stability during 48-hour continuous filtration. The MXene/COF membrane opens a novel avenue for fabricating versatile heterostructured membranes for advanced separations.
研究领域:
材料科学
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环境工程
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化学工程
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Device
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2025
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IF 8
Weikang Wang,Yan Bai,Ning Ding,Zhen You,Weiwei Zhao,Pin Yang,Mingli Liang,Shujuan Liu,Qiang Zhao
Photo-assisted flexible supercapacitors have emerged as transformative power solutions by integrating with solar photoirradiation-enhanced capacity (PIEC) to improve energy storage performance. However, the photogenerated carrier recombination and structural instability of existing metal oxides and carbon-based photoelectrodes hinder enhancement of PIEC performance in flexible supercapacitors for wearable electronics. Herein, we propose a dynamic bonding strategy to construct a core-shell covalent organic framework/MXene heterostructure (COF-316-Ti 3 C 2 T x ) with engineered heterointerfaces for flexible photo-enhanced micro-supercapacitors (FPMSCs). This method facilitates the oriented growth of covalent organic framework-316 (COF-316) on a Ti 3 C 2 T x nanosheet to form a core-shell heterostructure by anchoring monomers. Theoretical calculations and experiments reveal that the built-in electric field modulation accelerates photogenerated electron transfer and suppresses charge recombination (carrier lifetime is doubled). The core-shell heterostructure endows the realization of FPMSCs with enhanced mechano-electrochemical stability, including 180° bending stability and 97.5% of capacitance retention after 10,000 cycles.
研究领域:
材料科学
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纳米科技
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电化学
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能源存储
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柔性电子学
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高影响因子
ANALYTICA CHIMICA ACTA
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2026
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IF 6.1
Siqing Liu,Liping Chen,Xingju Li,Ruxi Lin,Yunxin Zhang,Xiaojun Luo
Background β 2 −agonists, also known as β 2 −adrenoceptor agonists, are secreted by the adrenal medulla of the animal body and have a characteristic catecholamine structure. When inhaled, the drug rapidly relaxes the smooth muscles of the airways in asthma patients, improves ventilation, and temporarily increases alertness during exercise and helps relieve fatigue. However, the use of β 2 −agonists to improve physical performance in a short period of time can lead to extreme dependence and irritation, and there are still many unknown hazards. They are now on the World Anti−Doping Organization (WADA) prohibited list. Results Surface−enhanced Raman spectroscopy (SERS) can directly detect the characteristic peaks associated with β 2 −agonist compounds in a fast and sensitive manner. This study is the first to utilize a direct Raman detection technique, achieving successful acquisition of the fingerprint spectra of three target analytes (vilanterol, fenoterol, bambuterol) as well as the establishment of a corresponding fingerprint spectral analysis method. To further improve its performance, in this study, gold nanoparticles were synthesized via redox methods and integrated with covalent organic framework (COF) to construct a novel highly sensitive detection platform for β 2 −agonists. The Au−COF composite exhibits high adsorption performance and can significantly enhance the SERS signal of the target, thereby achieving low detection limits, including 9.25 × 10 −6 g·mL −1 for bambuterol, 9.76 × 10 −6 g·mL −1 for vilanterol, and 7.54 × 10 −6 g·mL −1 for fenoterol, which makes it promising for improving the overall sensitivity of β 2 −agonist detection. Significance This study develops a novel analytical method utilizing Au−COF composites for highly sensitive SERS detection. It pioneers the application of this strategy in the qualitative and quantitative analysis of trace β2-agonists. The research not only significantly expands the scope of Au−COF composites but also provides a technologically promising approach with substantial practical value for ensuring medical safety through clinical medication monitoring and for detecting banned substances in sports.
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Advanced Membranes
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2024
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IF 0
Meixia Shan,Chaoqun Niu,Decheng Liu,Dongyang Li,Xueling Wang,Junyong Zhu,Qun Xu,Jorge Gascon,Yatao Zhang
Covalent organic frameworks (COFs) featuring high porosity and well-defined pore structures are attractive candidates for organic solvent nanofiltration (OSN). However, preparing defect-free COF membrane and manipulating pore size for precise molecular separation in OSN remains a significant challenge. Herein, we address this challenge by developing composite membranes through molecular soldering a benzimidazole-linked polymer (BILP-101x) onto a continuous ACOF-1 membrane. The shared monomer of ACOF-1 and BILP-101x promotes good compatibility, allowing the amorphous BILP-101x chemically stitch the grain boundary defects of the crystalline ACOF-1 layer and create narrow, staggered pores at the interface, thereby enhancing the OSN performance. Non-equilibrium molecular dynamics simulations were employed to reproduce and explain the permeability order of the solvents and dyes, revealing a hydrogen-bond cluster permeation mode for alcohols. Furthermore, the optimized BILP-101x/ACOF-1 composite membrane exhibits excellent ethanol permeance (13.2 L m −2 h −1 bar −1 ) and outstanding rejection towards various dye molecules, together with desirable and stable OSN performance under continuous filtration operation. This work opens a new avenue for improving the separation performance of continuous COF membranes in OSN applications.
研究领域:
材料科学
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化学工程
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膜分离技术
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INDUSTRIAL CROPS AND PRODUCTS
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2026
·
IF 6.4
Wei Yang,Xiaoyu Du,Hailiang Nie,Yanqing Qu,Hongge Jia,Yongqi Sun,Elena Sashina,Jingyu Xu
CMCS@COF composite aerogels were prepared via chemical crosslinking. • Aerogel adsorbs MG/MB/CV via synergistic electrostatic, π-π, hydrogen bond. • Aerogels' 3D network significantly improves stability and repeatability. • COF introduction increased aerogel's surface area and adsorption performance. With the accelerated industrialization, dye wastewater poses severe threats to the ecological environment and human health. In this study, sulfonated COF was synthesized via a solvothermal method, then crosslinked with CMCS, and the CMCS@COF composite aerogel with a 3D network structure was fabricated via freeze drying. The maximum adsorption capacities of the as prepared material for MG, MB and CV reach 2062.95, 510.96 and 1523.21 mg·g −1 , respectively. This performance is far superior to that of pure CMCS aerogel (228.16, 167.87 and 193.96 mg·g −1 , respectively), and also significantly higher than that of most reported COF based composite adsorbents. The adsorption process conforms to the Langmuir isotherm model and the pseudo second order kinetic model, indicating that the adsorption is monolayer chemisorption, and the mechanism involves the synergistic effects of electrostatic attraction, π-π stacking and hydrogen bonding. Compared to traditional powdered covalent organic framework materials, the developed aerogel exhibits excellent structural stability and convenient solid liquid separation capability, addressing engineering bottlenecks such as powder aggregation and difficult recovery. After five consecutive adsorption desorption cycles, no significant pore collapse was observed in the structure, demonstrating excellent regeneration performance. This strategy provides a technically feasible solution for the practical application of COF based adsorbents in dye wastewater treatment, achieving a balance between high adsorption capacity and operational recyclability. Download: Download high-res image (380KB) Download: Download full-size image
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