Nature Photonics
·
2025
·
IF 32.9
Zhai Jianxin,Wang Ruo-Ya,Chen Xiao,Zhou Baowen,Xia Zhanghui,Wu Haihong,Xue Teng,Jia Shuaiqiang,Chen Chunjun,Jing Lihong,He Mingyuan,Han Buxing
The photon-mediated conversion of CH 4 and CO 2 represents a green and sustainable route for producing transportation fuels and chemicals. Here we report an innovative, catalyst-free strategy for the conversion, by light, of CH 4 and CO 2 into CO/H 2 and C 2 H 6 . High-energy photons with a wavelength of 185 nm were found to initiate the reaction, and the additional use of photons with different energies at longer wavelengths further improved the reaction efficiency. In particular, the combination of 185-nm and 200–1,100-nm photons enabled CO, H 2 and C 2 H 6 production rates of 3.1 mmol m −3 h −1 , 1.93 mmol m −3 h −1 and 2.53 mmol m −3 h −1 , respectively. Moderate addition of H 2 O was found to aid the reaction considerably. Moreover, a total gas conversion of 1.51% (24 h) was achieved in experiments simulating an oxygen-free environment. This work opens up a promising route for producing fuels and chemicals using CH 4 and CO 2 without the use of any catalysts, under ambient conditions.
研究领域:
能源化学
·
环境科学
·
光化学
·
可持续能源
·
绿色化学
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Li Haobo,Zhu Yicheng,Zhao Zihan,Ma Ruixin,Lu Jiachen,Wan Wenjie,Chen Qianli
Ionic transport in solids is a critical process for energy devices including batteries and fuel cells. To improve ionic transport, an emerging approach is the selective excitation of atomic vibrations related to the mobile ions. However, there is limited direct experimental evidence demonstrating enhanced macroscopic ionic conductivity through this approach. Here, we use a 140 mW continuous-wave mid-infrared (MIR) light to excite the O–H stretch vibration in proton-conducting yttrium-doped barium zirconate. We observe reversible enhancement of 36.8% in bulk, and 53.0% in grain boundary proton conductivities, controlled by MIR irradiation. Decreases in the activation energy and prefactor for bulk proton conduction suggest possible reduction in activation entropy and attempt frequency of proton hopping. We rationalize the enhancement as the excitation of O–H stretch vibrational states, followed by the relaxation into lattice vibration modes, modulating the potential energy surface of the proton. Our findings highlight MIR irradiation as a power-saving strategy to optimize the performance and operation cost of solid-state electrochemical devices by selective modulation of the vibrational properties.
研究领域:
材料科学
·
电化学
·
固体物理
·
光学
·
能量存储与转换
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOMATERIALS
·
2025
·
IF 12.9
Shiman Lu,Zhaoqing Shi,Chendi Ding,Wenyan Wang,Weilang Zhang,Li Huang,Jiachan Lin,Xinpei Wang,Ran Luo,Xiaowei Zeng,Wenhu Zhou,Hongzhong Chen,Qiangsong Wang,Lin Mei
The targeted protein degradation (TPD) strategy modulates tumor growth pathways by degrading proteins of interest (POIs) and has reshaped anti-tumor drug research and development. Recently, the emergence of photodegradation-targeting chimeras (PDTACs) and laser irradiation at specific sites enables precise spatiotemporal controllability of TPD. Capitalizing on the advances of PDTACs, herein, we report a nanoplatform for efficiently delivering PDTAC molecule for photodegradation of bromodomain-containing protein 4 (BRD4) proteins, the key activators of oncogenic transcription. The PDTAC molecule, named as PPa-JQ1, is synthesized through the covalent attachment of the BRD4-targeting ligand JQ1-acid, to the photosensitizer pyropheophorbide-a (PPa), utilizing a 1,6-hexanediamine linker. The PPa-JQ1 is further encapsulated by human serum albumin (HSA) to obtain the HSA@PPa-JQ1 nanoplatform, which facilitates targeted and efficacious delivery to melanoma lesions. Both in vitro and in vivo therapeutic outcomes demonstrate that HSA@PPa-JQ1 can efficiently generate reactive oxygen species (ROS) to degrade BRD4 upon light irradiation, which eventually induces tumor death. Our study represents the first case to validate the anti-tumor therapeutic efficacy of PDTACs by systemic administration, providing the foundation for further application of PDTACs.
研究领域:
肿瘤学
·
药学
·
纳米技术
·
光化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Scientific Reports
·
2024
·Vol. 14
·期 1
·1-11
·
IF 3.8
Xu Feng,Jin Hang,Wu Huiquan,Jiang Acan,Qiu Bin,Liu Lingling,Gao Qiang,Lin Bin,Kong Weiwei,Chen Songyue,Sun Daoheng
Hydrogels are extensively explored as biomaterials for tissue scaffolds, and their controlled fabrication has been the subject of wide investigation. However, the tedious mechanical property adjusting process through formula control hindered their application for diverse tissue scaffolds. To overcome this limitation, we proposed a two-step process to realize simple adjustment of mechanical modulus over a broad range, by combining digital light processing (DLP) and post-processing steps. UV-curable hydrogels (polyacrylamide-alginate) are 3D printed via DLP, with the ability to create complex 3D patterns. Subsequent post-processing with Fe 3+ ions bath induces secondary crosslinking of hydrogel scaffolds, tuning the modulus as required through soaking in solutions with different Fe 3+ concentrations. This innovative two-step process offers high-precision (10 μm) and broad modulus adjusting capability (15.8–345 kPa), covering a broad range of tissues in the human body. As a practical demonstration, hydrogel scaffolds with tissue-mimicking patterns were printed for cultivating cardiac tissue and vascular scaffolds, which can effectively support tissue growth and induce tissue morphologies.
研究领域:
生物材料学
·
组织工程学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Science
·
2024
·Vol. 11
·期 26
·2402824
·
IF 14.3
Chen Fei Dai,Qing Li Zhu,Olena Khoruzhenko,Michael Thelen,Huiying Bai,Josef Breu,Miao Du,Qiang Zheng,Zi Liang Wu
Creatures, such as Venus flytrap and hummingbirds, capable of rapid predation through snap-through transition, provide paradigms for the design of soft actuators and robots with fast actions. However, these artificial “snappers” usually need contact stimulations to trigger the flipping. Reported here is a constrained anisotropic poly( N -isopropylacrylamide) hydrogel showing fast snapping upon light stimulation. This hydrogel is prepared by flow-induced orientation of nanosheets (NSs) within a rectangular tube. The precursor containing gold nanoparticles is immediately exposed to UV light for photopolymerization to fix the ordered structure of NSs. Two ends of the slender gel are clamped to form a buckle with bistability nature, which snaps to the other side upon laser irradiation. Systematic experiments are conducted to investigate the influences of power intensity and irradiation angle of the laser, as well as thickness and buckle height of the gel, on the snapping behaviors. The fast snapping is further used to kick a plastic bead and control the switch state. Furthermore, synergetic or oscillated snapping of the gel with two buckles of opposite directions is realized by inclined irradiation of a laser or horizontal irradiation with two lasers, respectively. Such light-steered snapping of hydrogels should merit designing soft robots, energy harvests, etc.
研究领域:
软体机器人
·
材料科学
·
仿生学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-10
·
IF 14.7
Yang Shuang,Yuan Huiqing,Guo Kai,Wei Zuting,Ming Mei,Yi Jinzhi,Jiang Long,Han Zhiji
The utilization of low-energy photons in light-driven reactions is an effective strategy for improving the efficiency of solar energy conversion. In nature, photosynthetic organisms use chlorophylls to harvest the red portion of sunlight, which ultimately drives the reduction of CO 2 . However, a molecular system that mimics such function is extremely rare in non-noble-metal catalysis. Here we report a series of synthetic fluorinated chlorins as biomimetic chromophores for CO 2 reduction, which catalytically produces CO under both 630 nm and 730 nm light irradiation, with turnover numbers of 1790 and 510, respectively. Under appropriate conditions, the system lasts over 240 h and stays active under 1% concentration of CO 2 . Mechanistic studies reveal that chlorin and chlorinphlorin are two key intermediates in red-light-driven CO 2 reduction, while corresponding porphyrin and bacteriochlorin are much less active forms of chromophores.
研究领域:
化学
·
生物化学
·
能源科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ChemistrySelect
·
2024
·Vol. 9
·期 41
·e202403137
·
IF 1.9
Hua-Ying Chen,Jian Lv,Ruo-Can Qian,Da-Wei Li,Bin-Bin Chen
Graphical Fluorescent scandium microspheres for highly efficient white-light photocatalysis. Scandium-based fluorescent microspheres (Sc-FMs) are prepared by a facile one-pot hydrothermal polymerization method, which can be well used for the highly-efficient photodegradation of dye pollutants (rhodamine 6 G) under low power white light without the assistance of any radical generating agents due to the strong generation ability of ⋅O 2 - and h + by Sc-FMs Efficient photocatalysts play an important role in the various fields such as pollutant treatment and the generation of clean energy. Therefore, developing a photocatalyst with high activity is of great significance. Herein, scandium-based fluorescent microspheres (Sc-FMs) are facilely prepared through the one-pot hydrothermal polymerization of scandium ions and tartaric acid. The prepared Sc-FMs show strong blue solid-state fluorescence, with a maximum emission at 412 nm. Meanwhile, Sc-FMs possess a strong white-light photocatalysis ability, which can be used for the photodegradation of dye pollutants (rhodamine 6 G) under low power white light without the assistance of any radical generating agents. In addition, the Sc-FMs display good stability and recyclability. As a result, this new and efficient Sc-FMs photocatalysts hold a promise for potential applications in environmental treatment.
研究领域:
环境科学
·
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Haiman Xu,Rongzhen Liu,Chonggao Bao,Hao Li,Zhichao Cao,Na Huang
Aluminum nitride (AlN) ceramics are increasingly utilized across various applications due to their exceptional theoretical thermal conductivity. To enable the fabrication of AlN ceramics with customized structures, digital light processing (DLP) technology has been explored for producing complex geometries. However, challenges arise due to AlN’s high refractive index and susceptibility to moisture absorption, which affect the curing characteristics and rheology of AlN slurries used in DLP. This study systematically examined the curing behavior and rheological properties of AlN slurries. Initially, the impact of photosensitive resin compositions and photoinitiators on curing depth and excess width were investigated. The results revealed that with a resin mixture ratio of 3:4:3 (mixed resin, high refractive index resin, and 9,10-Diphenylanthracene) and the addition of 5wt% of 2,4,6-trimethylbenzoyl-diphenyl phosphine oxide, the optimal curing depth of 90 μm was achieved, with an excess width of less than 0.1 mm. Additionally, the incorporation of 3wt% KH560 reduced the sedimentation rate and viscosity. The AlN slurry with 50vol% solid loading was prepared with the high curing depth of 73μm and low viscosity of 20.5 Pa.s at the shear rate of 27s -1 . Subsequently, the effects of buring powder for debinding process was investigated. Finally, a AlN ceramic body with a porosity of 2.97 %, bulk density of 3.08g/cm 3 , and flexural strength of 107.2MPa was obtained upon sintering at 1900 °C for 4 h.
研究领域:
材料科学
·
陶瓷制造
✓ 已验证
产品关联
DOI
高影响因子
POLYMER
·
2025
·
IF 4.5
Jiahuan Wang,Yuanyang Xu,Dongfei Zhang,Wenkai Liu,Zhen Li,Jiehua Li,Feng Luo,Hong Tan
Multifunctional biomaterials are vigorous development in recent period. Implanting biomaterials with minimal invasion and antibacterial activity are relentless demand. Herein, copper ion-loaded polydopamine nanoparticles (Cu(II)@PDA NPs) were incorporated into shape memory polyurethane (SMPU) to obtained 4D printable nanocomposites with excellent near-infrared (NIR) light responsiveness and antibacterial properties, which are crucial for tissue engineering applications. Firstly, a series of well-dispersed Cu(II)@PDA/PU nanocomposites were successfully prepared, and their structure and properties were systematically investigated. The nanocomposites showed robust mechanical properties and good biocompatibility. Then, under 808 nm NIR laser irradiation, the nanocomposites exhibited significant photothermal effects. Typically, it reached temperature of 53.5 °C for Cu(II)@PDA 0.5 /PU in 10 min under NIR. So that, it achieved 92.7 % antibacterial efficiency to avoid implant infection. Finally, the 4D printing capability of the shape memory nanocomposite was demonstrated, which showed rapid shape recovery within 16 s. Due to their multifunctionality, the nanocomposites hold great potential for use in minimally invasive implant biomaterials.
研究领域:
生物材料学
·
组织工程学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
Laser & Photonics Reviews
·
2024
·
IF 9.8
Zhi Chen,Hao Huang,Jiefeng Deng,Changle Meng,Yule Zhang,Taojian Fan,Lude Wang,Shuo Sun,Yi Liu,Huiling Lin,Shuang Li,Yunpeng Bai,Lingfeng Gao,Junle Qu,Dianyuan Fan,Xueji Zhang,Han Zhang
Genetic engineering faces persistent challenges in achieving precise Deoxyribonucleic acid (DNA) cleavage, especially with the limitations associated with current enzyme-based methods, exemplified by issues in CRISPR technologies. This study introduces a groundbreaking approach: utilizing reactive oxygen species (ROS) generated by Multiphoton Absorption (MPA)-excited Black Phosphorus Quantum Dots (BPQDs) under femto-second laser irradiation. This innovative method not only allows excitation with lower energy but also enhances overall efficiency. The integration of complementary RNA sequences facilitates high-efficiency, site-selective DNA cleavage in the system, named “TADPOLE” (Targeted DNA Precision Oriented Laser Excision). Beyond its precision in targeting arbitrary DNA sequences using quantum dots, TADPOLE harnesses the unique multiphoton absorption property of BPQDs, enabling excitation with lower-energy light sources suitable for in vivo applications in the future. Moreover, the approach integrates guiding RNA and ultrafast laser technology to provide precise control over local ROS generation and minimal heat production. This guarantees site-specific DNA cleavage while mitigating the risk of damage to non-targeted sequences. In summary, this study catalyzes advancements in enzyme-free DNA cleavage technologies, with transformative implications for genetic engineering, biotechnology, and medicine. The holistic precision, versatility, and endurance presented by TADPOLE open new avenues for targeted gene therapies and transformative applications in related fields.
研究领域:
遗传学
·
生物技术
·
医学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Chao Gao,Ye Feng,Suyi Liu,Bin Chen,Miaomiao Ding,Dailing Du,Wenjing Zhang,Daniela A. Wilson,Yingfeng Tu,Fei Peng
Combining artificial cellular compartmentalization and intelligent motion benefits of micro/nanomotors, light is used as energy input to construct an artificial cell-based micromotor capable of photosynthetic anabolism and intelligent directional movement. This system is assembled from phospholipids functionalized with F-ATP synthase and molybdenum disulfide (MoS 2 ) nanoparticles (Vesical@MoS 2 -ATPase). The underlying mechanism involves the generation of protons (H + ) through photo-hydrolysis of MoS 2 nanoparticles within vesicles, which generates a local electroosmotic flow inside the vesicles and drives the negatively charged MoS 2 toward light. The established proton gradient across the phospholipid membrane, in turn, drives the ATP synthase to catalyze ATP production. Both in vitro and in vivo models demonstrate that the micromotor can elevate local intracellular ATP levels upon light and improve the metabolism of denatured chondrocytes. This cell mimicry, with capabilities of migration and biosynthesis, emerges as a promising platform for the next generation of functional bio-interface.
研究领域:
生物医学工程
·
纳米医学
·
再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS
·
2025
·Vol. 25
·期 7
·2051
·
IF 3.5
Chuang Wang,Hao Wu,Quanwang Niu,Xiaohong Yan,Xiangfu Wang
While liquid crystal elastomers (LCEs) show promise for diverse soft actuators due to their strong stimulus responsiveness, limited investigation into their light perception and processing restricts their wider use in intelligent systems. This study employs a hollow double-layer structure to design light-controlled logic soft switches based on LCEs. The design realizes digital logic circuits including AND gates, OR gates, and NOT gates, as well as an optical switch array capable of converting light signals into visualized digital signals. These light-controlled soft switches exhibit strong photothermal responsiveness (~12 s), high programmability, and excellent cyclic stability (>500 times). This research provides a new perspective on light-controlled logic soft switches and their applications in logic circuits.
研究领域:
材料科学
·
光学工程
·
智能系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）