INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
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2013
·Vol. 48
·期 11
·2324-2330
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IF 1.24
Ming Cai,Xiangyang Guo,Hanhua Liang,Peilong Sun
Summary In this study, microwave-assisted extraction with ethanol (MAEE) of star anise oil from Illicium verum Hook.f . has been optimised by response surface methodology (RSM). A maximum yield of star anise oil was obtained at an optimum condition: the ratio of solvent to sample 17 mL g −1 , extraction time 16 min and microwave power 505 W. Accordingly, the highest yield of star anise oil was about 24.98%, which was much higher than that of steam distillation (SD), 7.17%. Oxygenated organic compounds in representative of trans-anethole are a major component in star anise oil, nearly 94.21% for SD and 86.66% for MAEE, identified and determined by GC-MS. The oils extracted by SD and MAEE both have strong antioxidant activities that were demonstrated by the DPPH and ABTS assays.
研究领域:
植物化学
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食品科学
·
分析化学
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高影响因子
POLYMER
·
2016
·
IF 3.586
Liao Peng,Zilin Wang,Anchao Feng,Meng Huo,Tommy Fang,Ke Wang,Yen Wei,Jinying Yuan
Research interest in electrochemical redox stimulus has grown considerably due to its easy trigger mode, in which the linkers have played important roles, such as the β-cyclodextrin-ferrocene (β-CD-Fc) linker. Star amphiphilic copolymers with well-defined and flexible structures are considered to be excellent choices for drug delivery systems (DDSs). Driven by the idea that using star polymers to improve the biocompatibility and efficiency of the β-CD-Fc-based DDS, we designed and synthesized star polymer 4 arm-poly(ε-caprolactone)-β-CD ( 4A PCL-CD ) and linear polymer polyethylene glycol-Fc ( PEG-Fc ). They can form supramolecular block copolymer 4A PCL-CD / Fc-PEG and self-assemble to micelles , which are electrochemical responsive and can be applied as drug carriers for potential controlled release, with higher efficiency and better biocompatibility compared with their linear analogues.
研究领域:
材料科学
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药物递送系统
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生物医学工程
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EUROPEAN POLYMER JOURNAL
·
2023
·
IF 6
Shusu Ren,Xiang Xu,Jiyuan Sun,Haitao Zhao,Weiwei He,Lifen Zhang,Zhenping Cheng
Antimicrobial resistance is still a major clinical challenge worldwide today and the development of novel antimicrobial agents with high antimicrobial activity and low bacterial resistance is of great importance. In this work, quaternized 2-(dimethylamino) ethylmethacrylates iodonium salt-type monomers with different lengths of pendent alkyl (qDMAEMA(C x ), x = 3, 6 and 8) are synthesized for preparation of a series of cationic porphyrin-based star-shaped (co)polymers by photo-controlled bromine-iodine transformation reversible-deactivation radical polymerization (BIT-RDRP). Especially, qDMAEMA(C x ) not only acts as a monomer but also can be used as an intrinsic catalyst for the BIT-RDRP. In addition, effects of alkyl chain length (x), degree of polymerization and hydrophilic-hydrophobic balance ( H.L.B. ) on the antibacterial activity of the prepared (co)polymers are investigated. The resulting zinc ion coordinated copolymers [email protected] (qDMAEMA(C 8 ) 20 - co -PEGMA 35 ) (denoted as [email protected] ) exhibits good water solubility and is able to be absorbed effectively on the surfaces of bacteria, exhibiting excellent photodynamic inhibition activity against both S. aureus and E. coli under irradiation with 570 nm light source according to the coated plate experiments. The minimum bactericidal concentration (MBC) of [email protected] against S. aureus and E. coli are 1.5 and 2.0 μM, respectively, in the presence of light. Meanwhile, [email protected] shows quite low cytotoxicity and satisfying photolysis ability at working concentrations, displaying promising biological application prospects.
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Polymer Chemistry
·
2022
·Vol. 13
·期 14
·2026-2035
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IF 5.364
Wencheng Shi,Boyu Wu,Xiaofeng Guo,Anchao Feng,San H. Thang
Fluorescent end-functional mikto-arm star copolymers were prepared by an “arm-first” approach mediated by a mixture of macro-RAFT agents. RAFT copolymerization of coumarin-POEGMA, boron-dipyrromethene (BODIPY)-PDMA and bisindolylmaleimide (BIM)-PNIPAM with different fluorophore-labeled end-groups was performed with polyethylene glycol diacrylate as a cross-linker. The fluorescence spectra of fluorophore-labeled homopolymers showed that there was a good linear correlation existing between fluorescence intensity and polymer concentration in dilute solutions. According to the fluorescence results, after carefully choosing the peaks and calculation, the arm components of star polymers can be quantitatively analyzed with obvious similarity to 1H NMR approaches which are considered to be less valid in a complicated chemical environment. Overall, it is reasonably expected that the current study expands the characterization methods for star polymers and promotes the development of the synthesis of well-defined multifunctional star polymers.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 24
·52326
·
IF 3.057
Qintian Gu,Guixiang Cheng,Bowen Ji,Jian Hu,Xibin Yue,Qiuyue Guo,Chongyang Mai,Li Yang,Chengcheng Lv,Hongwen Zhang,Yan Jiang
In this article, the titanium-oxo cluster containing bromine had been prepared by solvothermal synthesis, which was used to initiate the atom transfer radical polymerization of butyl methacrylate in order to obtain organic–inorganic hybrid materials. The structures and compositions of titanium-oxo cluster and its hybrid materials were characterized by X-ray photoelectron spectroscopy (XPS), 1 H nuclear magnetic and infrared spectra tests. The hybrid materials with different molecular weights were dissolved in tetrahydrofuran and coated on the surface of polyethylene terephthalate (PET) film, which was used to study the surface properties. Compared with 89.7% light transmittance of the pure PET film, the light transmittance of the modified films was up to 93.3%. Meanwhile, the water contact angles of the modified films also significantly increased. It would be conducive to the self-cleaning of the film surface. The coatings prepared by the static respiration diagram method had better hydrophobic effect and show the performance of light scattering. All of that could be proved through the scanning electron microscope (SEM) images. The elastic modulus and hardness of hybrid materials also change with the increase of molecular weight. In addition, the T g of the hybrid materials increased, which means they have better thermal stability than that of Polybutylmethacrylate (PBMA).
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LANGMUIR
·
2021
·
IF 3.882
Huimin Kong,Wenjie Zhang,Ge Shi,Zhe Cui,Peng Fu,Minying Liu,Yanjie He,Xiaoguang Qiao,Xinchang Pang
A colloidal nanocrystal cluster (CNC) is a hierarchical nanostructure formed by clustering several nanocrystals into one nano-ensemble, which may exhibit unique optical or catalytic properties different from individual nanocrystals owing to the mutual interactions among neighboring component nanocrystals. However, there is still no universal synthetic route that could be applicable to diverse material compositions with precisely controlled hierarchical structures (i.e., nanocrystal number density, component nanocrystal size, and overall diameter of the CNC) up to now. Herein, a general and novel synthetic strategy was reported for crafting a wide range of inorganic CNCs (i.e., noble metal, semiconductor, and metal oxide) via utilizing amphiphilic star-like poly(4-vinylpyridine)-block-polystyrene diblock copolymers as nanoreactors prepared by sequential atom transfer radical polymerization. The hierarchical structure of rationally designed CNCs could be readily tailored by varying the P4VP molecular weight of star-like nanoreactors and the parameter optimization during the CNC preparation process, which was inaccessible by conventional synthetic methods.
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PubMed
高影响因子
EUROPEAN POLYMER JOURNAL
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2020
·
IF 3.862
Youjun He,Jiming Chen,Irum Rafique,Zaijun Lu
The catechol groups in mussel adhesive proteins exhibit excellent adhesion property to the skin and tissue surfaces. Inspired by catechol groups, the aim of this study is to synthesize the star-shaped polycaprolactone bio-adhesive bearing catechol end-groups (s-PCL 19 -CA 9 ). Firstly, star-shaped polycaprolactone was synthesized through ring-opening polymerization of caprolactone monomers initiated by β-cyclodextrin, and then the s-PCL 19 -CA 9 was obtained through end-group functionalization using succinic anhydride and dopamine. The structure of s-PCL 19 -CA 9 was characterized by 1 H NMR, FTIR, and static light scattering. Adhesive strength measurements demonstrate that the incorporation of multifunctional catechol groups endows the crosslinked s-PCL 19 -CA 9 with an excellent adhesion property (102 ± 10 kPa). The swelling ratio of crosslinked s-PCL 19 -CA 9 is as low as 3.4 ± 0.2% owing to the hydrophobicity of PCL and the crosslinking structures. Besides, the cytotoxicity studies show that s-PCL 19 -CA 9 is noncytotoxic. The TGA measurements indicate that s-PCL 19 -CA 9 possesses a good thermal stability. Therefore, this work provides a new way for developing multifunctional bio-adhesives with excellent adhesion property and low swelling ratio.
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Biomaterials Science
·
2021
·Vol. 9
·期 7
·2721-2731
·
IF 6.843
Hao Liu,Xu Zhang,Ziyin Zhao,Fangping Yang,Ruizhong Xue,Lichen Yin,Ziyuan Song,Jianjun Cheng,Shifang Luan,Haoyu Tang
Antimicrobial peptides (AMPs) have been considered as a promising new tool to combat the antimicrobial resistance (AMR) crisis. However, the high toxicity and high cost of AMPs hampered their further development. Herein, a series of star poly(L-lysine) (PLL) homo- and copolymers with excellent antimicrobial activity and improved biocompatibility were prepared by the combination of ultra-fast ring opening polymerization (ROP) and side-chain modification. The amine-terminated polyamidoamine dendrimer (Gx-PAMAM) mediated ROP of Nε-tert-butyloxycarbonyl-L-lysine N-carboxyanhydride (Boc-L-Lys-NCA) and γ-benzyl-L-glutamic acid-based N-carboxyanhydride (PBLG-NCA) was able to prepare star PLL homo- and copolymers with 400 residues within 50 min. While the star PLL homopolymers exhibited low minimum inhibitory concentration (MIC = 50–200 μg mL−1) against both Gram-positive and Gram-negative bacteria (i.e., S. aureus and E. coli), they showed high toxicity against various mammalian cell lines. The star PLL copolymers with low contents of hydrophobic and hydroxyl groups showed enhanced antimicrobial activity (MIC = 25–50 μg mL−1) and improved mammalian cell viability. Both SEM and CLSM results indicated the antimicrobial mechanism of membrane disruption.
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PubMed
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BIOCONJUGATE CHEMISTRY
·
2019
·
IF 4.349
Jian-Bin Zhen,Peng-Wei Kang,Mu-Han Zhao,Ke-Wu Yang
The traditional antibiotics have specific intracellular targets and disinfect in chemical ways, and the drug-resistance induced by the antibiotics has grown into an emerging threat. It is urgent to call for novel strategies and antibacterial materials to control this situation. Herein, we report a class of silver-decorated nanocomposite AgNPs@PCL-b-AMPs as potent nanoantibiotic, constructed by ring-opening polymerization of the monomers ε-caprolactone, Z-Lys-N-carboxyanhydrides (NCAs), and Phe-NCAs, then decorated with AgNPs, and characterized by SEM, TEM, and DLS. The biological assays revealed that the nanocomposite possessed strong antibacterial efficacy against both Gram-positive and Gram-negative bacteria including clinical isolated bacteria MRSA, VRE, P. aeruginosa, and K. pneumonia, exhibiting a MIC value range in 2–8 μg/mL. Importantly, the S. aureus and P. aeruginosa treated with the nanocomposite did not show drug-resistance even after 21 passages. Also, in vivo anti-infective assays showed that the nanocomposite was able to effectively kill bacteria in the infected viscera of mice. The study of the sterilization mechanism showed that the nanocomposite exhibited a multimodal antimicrobial mechanism, including irreversibly damaging the membrane structure, making the leakage of intracellular ions and subsequently inducing generation of the reactive oxygen species (ROS), ultimately sterilizing the bacteria. The nanocomposite exhibits effective broad-spectrum antibacterial properties and shows low toxicity to the mammalian cells/animal. Overall, the AgNPs@PCL-b-AMPs gained in this work show great potential as a highly promising antibacterial material for biomedical applications including drug-resistant bacterial infection.
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PubMed
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2017
·
IF 4.217
Rui Liu,Wanfen Pu,James J. Sheng,Daijun Du
This work fabricated a novel star-like hydrophobically associative polyacrylamide called SHPAM used in enhanced oil recovery (EOR) processes in harsh reservoir conditions. SHPAM composed of a core of nano-silica and a layer of amphiphilic-polymeric chains was synthesized via a facile water free radical polymerization. It was systematically characterized using TEM, SEM, IR, 1 H NMR and DLS. Measurements from solubility, thickening efficiency, long-term stability and rheological performance indicated that the three-dimensional microstructure and intermolecular associations provided SHPAM solution with fantastically comprehensive properties, outperforming hydrophobically associative polyacrylamide. The evidence from rectangle cores in a serial model experiments implied that SHPAM was well compatible with permeable cores and it had desirable injectivity with sustainable mobility control in porous media. Moreover, core flooding tests revealed that after extensive water flooding, SHPAM with the concentration of 1500 mg/L increased the oil recovery factor by 20% in sandstone cores. This study showed the robust potential of SHPAM as a polymer flooding candidate in high temperature and high salinity reservoirs where harsh conditions associated with lack of fresh water constrain the applications of conventional polymers.
研究领域:
石油工程
·
高分子化学
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POLYMER
·
2010
·Vol. 52
·期 2
·391-399
·
IF 3.573
Yuan Meng,Xing-Hong Zhang,Bin-Yang Du,Bo-Xuan Zhou,Xin Zhou,Guo-Rong Qi
Core crosslinked star (CCS) polymers, which have crosslinked poly (divinyl benzene-co-styrene) [P(DVB-St)] core and multiple arms of polystyrene- b -poly(ethylene oxide) diblock copolymer (PEO- b -PS) [denoted as PEO- b -PS/P(DVB-St) CCS], were synthesized via atom transfer radical polymerization(ATRP). PEO- b -PS/P(DVB-St) CCS polymer was spherical with average diameters of scores of nanometers from transmission electron microscopy (TEM) and dynamic light scattering (DLS), and blended with diglycidyl ether of bisphenol (DGEBA) and 4,4′-diamino diphenyl methane (DDM) in tetrahydrofuran (THF). With 5 or 10 wt% PEO- b -PS/P(DVB-St) CCS polymer, spherical core–shell nanodomains with average diameters of 29 or 32 nm were observed from atomic force microscopy (AFM), which were randomly distributed in the resultant thermosets . Considering the difference in miscibility of the epoxy with P(DVB-St) and PEO- b -PS after and before curing reaction, a reaction-induced microphase separation (RIMPS) mechanism was proposed to account for the formation of the core–shell nanodomains in the thermosets . During curing, the RIMPS of PS subchain occurred but was confined by P(DVB-St) core, resulting in formation of thermoplastic PS shell around the crosslinked core. Such core–shell nanodomain could be easily etched away by THF, whereas the control thermosets containing PEO/P(DVB-St) CCS polymer could not be etched by THF. The glass transition temperatures ( T g s) of the epoxy thermosets containing PEO- b -PS/P(DVB-St) CCS polymer were significantly improved compared with pure epoxy thermosets.
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FOOD CONTROL
·
2026
·
IF 7
Xiangmin Kuang,Qingbo Huang,Jiapeng Wu,Sakamon Devahastin,Chaofan Guo,Yongli Jiang,Junjie Yi
Pesticide residues on dried star anise remain major barrier to product safety and quality; current washing practices unfortunately fail to balance decontamination efficiency with retention of bioactive compounds. Suitability of emerging decontamination media, in particular alkaline electrolyzed water (ALEW), for star anise has nevertheless not been assessed. The present study therefore compared use of ALEW with use of conventional methods at ambient and high-temperature conditions to decontaminate star anise; four representative fungicides were tested. Quality of dried star anise was then determined in terms of color, rehydration behavior, shikimic acid and volatile oil contents. ALEW treatment at ambient temperature provided superior pesticide reduction (9.3–14.7%) compared with other treatments; such treatment also led to enhanced rehydration capacity and color. Unexpectedly, high-temperature soaking markedly reduced effectiveness of ALEW and caused significant losses of shikimic acid and volatile oils. Machine learning modeling identified support vector regression as most accurate tool to predict influences of pH, soaking temperature and soaking time of ALEW on pesticide residues decontamination and reveals distinct parameter sensitivities among different pesticides. Short-duration, ambient ALEW treatment offers practical and quality-preserving solution for pesticide control in star anise processing, with clear implications for sustainable spice manufacturing.
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危险品化学品经营许可证（带存储）