MICROCHIMICA ACTA
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2022
·Vol. 189
·期 5
·1-10
·
IF 6.408
Ding Jinglei,Zhang Wenqi,Xue Fengying,Sun Yu,Yan Quizhu,Chen Yanwei,Shan Guiye
Gold nanoclusters (AuNCs) are widely used in the fluorescence detection of biomolecules in human serum due to their good fluorescence properties, low toxicity, and better biocompatibility. However, the weak fluorescence intensity of AuNCs limits the fluorescence detection of molecules within a wide concentration range. It is reported that coating AuNCs in ZIF-8 with adjustable pore size can effectively improve the fluorescence intensity of AuNCs and broaden the detection range. And the AuNCs wrapped in the gaps of ZIF-8 can prevent the fluorescence quenching caused by the aggregation of AuNCs. However, ZIF-8 has high crystallinity, poor dispersion, and easy deposition, which reduces the fluorescence stability of the detection system and affects the detection. Based on the above research, the highly hydrophilic polymer PEI was modified to the surface of ZIF-8, and a kind of nanocomposite material AuNCs/ChOx@ZIF-8/PEI was obtained by co-encapsulating AuNCs prepared with glutathione as a ligand and cholesterol oxidase (ChOx) into ZIF-8 modified with PEI. The composite material emits strong red light at 650 nm under the excitation of 395-nm light, and the system can sensitively detect cholesterol (Chol) in human serum. Compared with other materials, the PEI-modified composite has better solubility and stability, so the detection effect of Chol is better. Encapsulation of ChOx in the ZIF-8 shell can protect the enzyme and increase the local concentration of ChOx, thereby speeding up the reaction rate. Compared with free AuNCs/ChOx, the quenching rate of AuNCs/ChOx@ZIF-8/PEI system is doubled. Secondly, the addition of Fe 2+ to the detection process results in higher quenching rate and detection sensitivity. The system can detect Chol in the concentration range 0.1–2.4 μM, with a detection limit of 0.073 μM. The determination is a fast and sensitive strategy. In addition, the practicability of this assay in the detection of Chol in human serum has been verified. Due to its selectivity and sensitivity, it has potential application value in clinical diagnosis. Graphical abstract
研究领域:
生物化学
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医学诊断
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纳米材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Huimin Yang,Xin Liu,Jihui Wang,Wenbin Hu
The following study is conducted to improve the corrosion resistance of magnesium alloy. First, ZnAl layered double hydroxide (ZnAl LDH) film was prepared on AZ61 magnesium alloy by using hydrothermal method. Then, as-prepared ZnAl LDH was put into 2-methylimidazole (2-mIm) solution to synthetize ZIF-8 film (ZIF-8/LDH). Finally, ZIF-8/LDH film synthesized ZIF-8-DMBIM film (ZIF-8-DMBIM/LDHs) via a shell-ligand-exchange-reaction in the methanol solution containing 5, 6-dimethylbenzimidazole (DMBIM). The surface morphology, structure, and composition of the composite film were observed and determined by scanning electronic microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and energy-dispersive X-ray spectroscopy. The wettability of composite film was measured by using a water contact angle meter, and the corrosion resistance of the composite film was estimated by the polarization curve and electrochemical impedance spectroscopy techniques. Results show that the prepared ZIF-8-DMBIM/LDH composite film has a dense hexagonal plate morphology with a two-layer structure and a thickness of 3.5 μm. Compared with ZnAl LDH and ZIF-8/LDH films, ZIF-8-DMBIM/LDH composite film has a high contact angle (115.7°), low corrosion current density, and high corrosion potential and polarization resistance due to its near-smooth surface, dense two-layer structure, and hydrophobic characters.
研究领域:
材料科学
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电化学
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 48
·期 4
·1642-1649
·
IF 3.3
Xurong Zuo,Pengfei Liu,Qinhao Sun,Jiahui Huang,Yuwei Zhang,Xuecheng Zhu,Runqi Chen,Xiangyu Meng
Because anthrax spores are highly lethal to humans and animals as well as potential biological warfare agents, there is a great need for rapid, sensitive, and selective quantification of dipicolinic acid (DPA) as a biomarker for anthrax spores. Herein, we prepared a novel lanthanide-doped nanoprobe by coordination of Tb3+ ions with tannic acid (TA)-coated zeolitic imidazolate frameworks-8 (ZIF-8) (ZIF-8@Tb–TA). The proposed assay was derived from the unsaturated coordination of Tb3+ ions. In the presence of DPA, Tb3+ ions could be sensitized to emit inherent luminescence due to the energy transfer after coordination with DPA. The results illustrated that ZIF-8@Tb–TA could be used as a sensitive nanoprobe for detecting DPA with a broad linear range (0 μM to 12.0 μM), and the limit of detection (LOD) was 12.3 nM. Moreover, the specific recognition ability of DPA by ZIF-8@Tb–TA was much better than that of other interfering molecules. This study proposed a new strategy to establish lanthanide-functionalized nanoprobes for highly selective and sensitive detection of DPA.
研究领域:
生物化学
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分析化学
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医学检测
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2019
·Vol. 9
·期 1
·117
·
IF 4.034
Hongmei Tang,Wenyao Li,Haishun Jiang,Runjia Lin,Zhe Wang,Jianghong Wu,Guanjie He,Paul Robert Shearing,Dan John Leslie Brett
The harmful nature of high concentrations of antibiotics to humans and animals requires the urgent development of novel materials and techniques for their absorption. In this work, CTAB (Cetyltrimethyl Ammonium Bromide)-assisted synthesis of ZIF-8 (zeolitic imidazolate framework)-derived hollow carbon (ZHC) was designed, prepared, and used as a high-performance adsorbent, and further evaluated by Langmuir and Freundlich isothermal adsorption experiments, dynamic analysis, as well as theoretical calculation. The maximum capacities of ZHC for adsorbing tetracycline (TC), norfloxacin (NFO), and levofloxacin (OFO) are 267.3, 125.6, and 227.8 mg g−1, respectively, which delivers superior adsorptive performance when compared to widely studied inorganic adsorbates. The design concept of ZIF-8-derived hollow carbon material provides guidance and insights for the efficient adsorbent of environmental antibiotics.
研究领域:
环境科学
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材料科学
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2018
·Vol. 20
·期 46
·7486-7491
·
IF 3.304
Guihuan Chen,Bing Yu,Chenghao Lu,Haohao Zhang,Youqing Shen,Hailin Cong
Encapsulating well-defined nanoparticles (NPs) into ZIF-8 to form core–shell structures not only can minimize the drawbacks and maximize the advantages of the disparate components but also may provide synergistic functionality. This work presents novel one-pot synthetic methods to produce Fe3O4@ZIF-8 NPs. Moreover, the morphology of Fe3O4@ZIF-8 NPs can be easily controlled by changing the synthesis conditions (time, temperature, and dosage). The as-obtained Fe3O4@ZIF-8 NPs have good dispersibility and a large specific surface area and they are proven to have potential applications as drug delivery models with good biocompatibility, high drug loading and good pH responsiveness.
研究领域:
材料科学
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药学
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纳米医学
✓ 已验证
DOI
高影响因子
DESALINATION
·
2017
·
IF 5.527
Tie Gao,Haibo Li,Feng Zhou,Mangmang Gao,Sen Liang,Min Luo
In this work, the capacitive deionization (CDI) behavior of mesoporous carbons (MCs) through direct carbonization of ZIF-8 at 1000 °C under Ar + 4%H 2 atmosphere has been explored. The obtained MCs exhibit a well-defined mesoporous structure, with a high specific surface area of 723.41 m 2 ·g − 1 and average pore diameter of 3.2 nm. The specific electrochemical capacitance of MCs was evaluated in a three-electrode configuration with 1 M NaCl electrolyte, showing that the capacitance reached as high as 215.72 F·g − 1 at the scan rate of 5 mV·s − 1 and 186 F·g − 1 with current density of 100 mA·g − 1 , respectively. Moreover, it is found that the electrosorption capacity of MCs was 4.8 mg·g − 1 in NaCl solutions with an initial concentration of 250 mg·L − 1 and cell voltage of 1.2 V. Remarkably, the theoretical maximum electrosorption capacity was estimated at 17 mg·g − 1 from Langmuir isotherm when the cell voltage was fixed at 1.2 V. Finally, the well regeneration of MCs electrode was demonstrated, indicating the great potential application of MCs in desalination .
研究领域:
材料科学
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环境科学
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电化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Xiaohong Hu,Jia Wen,Haibo Zhang,Qian Wang,Caiya Yan,Lang Xing
The most important thing to do with hexavalent chromium (Cr(VI)) removal in wastewater through adsorption-reduction method is to find an adsorbent that has both strong adsorbability and reducibility. Herein, an eco-friendly material ZIF-8-EGCG, which was a combination of epicatechin gallate (EGCG) and ZIF-8, was synthesized to treat Cr(VI)-containing wastewater. At room temperature, the maximum adsorption amount of Cr(VI) reached 136.96 mg·g −1 , and the Cr(VI) reduction rate (96%) was much better than that of the original ZIF-8 (37%). Such outcome was among the best in the existing studies using MOFs to treat Cr(VI). In addition, the characterization results showed that the surface of ZIF-8-EGCG was electronegative. The material was irregular sphere with pore size of 7.12 nm and BET surface area of 113.02 m 2 ·g −1 . The well-fitted Langmuir adsorption isotherm and pseudo first/second-order kinetics model suggested that the adsorption of Cr(VI) on ZIF-8-EGCG was governed by both physical and chemical processes. Stability results revealed that the overall stability of ZIF-8-EGCG due to the etched structure was slightly inferior to ZIF-8, especially at higher temperatures (>35 °C). Simultaneously, the reaction between ZIF-8-EGCG and Cr(VI) was a spontaneous, exothermic, entropic decrease process.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Biomaterials Science
·
2022
·Vol. 10
·期 17
·4837-4847
·
IF 7.59
Essam Abdo Mohammed Saad Obaid,Shuai Wu,Yuan Zhong,Meng Yan,Li Zhu,Bibo Li,Yi Wang,Wei Wu,Guixue Wang
Nanomedicines represent new promising strategies for treating atherosclerosis (AS), because they enhance drug bioavailability and have lower side effects. Nevertheless, nanomedicines have several challenges with these advantages, including a limited circulation life, lack of precise targeting, and insufficient control of drug release. Accordingly, the development of drug delivery systems (DDSs) with abilities to enhance the payload delivery to the AS plaque lesion and to control drug release can boost the therapeutic efficacy and safety for AS treatment. Herein, we employed a one-step self-assembly approach for effectively encapsulating the anti-AS drug simvastatin (SIM) in zeolitic imidazolate framework-8 (ZIF-8) (SIM/ZIF-8), and then coated it with hyaluronic acid (HA) to fabricate the SIM/ZIF-8@HA nanoplatform. The resulting nanoplatform could efficiently accumulate in plaque regions through the specific recognition between HA and CD44. Meanwhile, the acid environment breaks down ZIF-8 to release SIM. The in vitro and in vivo experiments demonstrated that SIM/ZIF-8@HA could inhibit the proliferation of smooth muscle cells and have good biocompatibility. Moreover, SIM/ZIF-8@HA can effectively suppress the development of AS plaques without any considerable side effects in mice treatments. The findings revealed that SIM/ZIF-8@HA may be a promising nanomedicine for safe and efficient anti-AS applications.
研究领域:
纳米医学
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药剂学
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心血管疾病治疗
✓ 已验证
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2022
·
IF 7.129
Yixuan Liang,Hanbing Li,Xiaotong Li,Qiyu Zhang,Jiaying Fei,Sumei Li,Sha Chen
Around 6.6 million tons of spent coffee is produced per year, resulting in resources loss and potential environmental risks. Hence, a green technique is required to reuse the spent coffee grains. In this study, coffee grounds were burnt at 900 °C to generate the biochar (BC) for the synthesis of the porous adsorbent (ZIF-8 @BC) by growing ZIF-8 on the surface of BC. We applied the well-prepared ZIF-8 @BC to remove Congo red (CR) in water. The maximum adsorption capacity of ZIF-8 @BC on Congo red in water was up to 1080.4 mg/g, which was significantly higher than that of many different types of BCs reported in previous studies. The reasons for its highly efficient adsorption of CR probably was attributed to metal ions and coordinatively unsaturated sites in the material. Also, BC enabled the less aggregation of ZIF-8 to provide sufficient specific surface area for CR adsorption. From the analysis of the pseudo-second-order kinetic model and Langmuir model, the adsorption of ZIF-8 @BC on CR was a homogeneously chemical adsorption process regulated by electrostatic interaction, π-π stacking and metal coordination.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Boli Zhao,Ying Wang,Junyi Che,Liquan Xiong,Di Gao,Dongsheng Chen
The development of a catalyst that is efficient, clean, simple, inexpensive, and conducive to a wide range of industrial applications is the key to achieving water electrolysis for hydrogen production. In this paper, iron-doped ZIF-67 materials were synthesized using a one-step hydrothermal method, with the different molar ratios of n (Fe3+): n (Co2+) = 0.05%, 1%, 2%, 5%, 10%. We found that trace amounts of iron greatly changed the particle size of ZIF-67. After high-temperature pyrolysis (400 °C, 600 °C, and 800 °C), the electrochemical results showed that the content of doped iron and different pyrolysis temperatures lead to different hydrogen evolution reaction (HER) effects. The 1% Fe/Co-600 sample with the overpotential (202 mV) at 10 mA·cm–2 and the Tafel slope (125.1 mV·dec–1) was significantly lower than other iron-doped materials and exhibited a better HER performance, though still higher than the commercial Pt/C (5 wt %) catalyst with the overpotential of 179 mV at 10 mA·cm–2 and the Tafel slope of 67.8 mV·dec–1. Significantly, the 1% Fe/Co-600 sample has strong stability. After pyrolysis, the 1% Fe/Co-600 sample still had a large specific surface area of 290.1763 m2·g–1 and a porous structure consisting of micropores and mesopores, which improved the catalytic effect. It may provide a new way to modify the catalyst geometry and design and prepare low-cost and high-activity Co-based catalysts.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Physical Chemistry C
·
2019
·
IF 4.309
Yongke Zhang,Zhiliang Jin
g-C3N4@ZIF-67 composite photocatalyst-supported NiSx are successfully prepared by a hydrothermal method using g-C3N4 and ZIF-67 as carriers. The synthesized composite catalyst has an efficient photocatalytic H2 production effect. Under visible light irradiation, the maximum H2 production within 5 h over the [g-C3N4@ZIF-67/(10%wt)NiSx] photocatalyst is 208 μmol, which is 8.32 times higher than that of pure g-C3N4. Based on the analysis of scanning electron microscopy and transmission electron microscopy, it is not only known that g-C3N4 and ZIF-67 provide space for the loading of NiSx nanoparticles but also that ZIF-67 as a carrier framework can effectively reduce the particle size of NiSx nanoparticles and increase the dispersion of NiSx. Further studies of photoluminescence (PL), time-resolved PL, i–t, linear scanning voltammetry, electrochemical impedance spectroscopy, and Mott–Schottky curves, we can not only know that the modification of NiSx nanoparticles do enhance the electron transfer ability but also that the matched conduction band position between g-C3N4 and ZIF-67 provides a feasible thermodynamic path for the transmission of electrons. Based on the DFT calculations, both NiS2 and Ni3S4 show the metallic characteristics, which means the outstanding electrical conductivity of them and implies the excellent capability to transport electrons. The work function of NiSx with metallic properties is more negative than that of the semiconductor, which indicates that the loading of NiSx can further promote the separation of electrons, thereby improving the H2 production efficiency.
研究领域:
材料科学
·
能源化学
·
催化科学
✓ 已验证
产品关联
DOI
高影响因子
Molecular Catalysis
·
2018
·
IF 0
Yanting Guo,Xing Chen,Xuan Zhang,Shujin Pu,Xutong Zhang,Chengli Yang,Dali Li
The immobilization of enzyme is an important biotechnology in industry. Enzyme immobilization by nanomaterials has attracted interest of researchers due to potentially promising application. Many enzymes had been successfully immobilized by different nanomaterials. In this work, β-glucosidase was immobilized by SiO 2 nanoparticles (nano-SiO 2 ) and zeolitic imidazolate framework-8 (ZIF-8), then the enzymatic properties of them were also compared. The nano-SiO 2 @β-glucosidase and the β-glucosidase@ZIF-8 achieved immobilization yield of 58.5% and 23.0%, respectively. Optimal temperature of the free β-glucosidase, nano-SiO 2 @β-glucosidase and the β-glucosidase@ZIF-8 were around 50 °C. Both free β-glucosidase and nano-SiO 2 @β-glucosidase showed maximal catalytic activity at pH 6.0, while the optimal pH of the β-glucosidase@ZIF-8 was 5.4 roughly. The nano-SiO 2 @β-glucosidase exhibited similar pH stability and thermal stability to those of the free β-glucosidase, and the β-glucosidase@ZIF-8 improved pH stability greatly. Moreover, after the treatment of trypsin for 4 h at 37 °C, the residual activities of the β-glucosidase@ZIF-8 was the highest that retained 94%, which provided huge potential for the application of the β-glucosidase@ZIF-8 in industry. Furthermore, the nano-SiO 2 @β-glucosidase and the β-glucosidase@ZIF-8 can be reused for 5 cycles with 87.5% and 88.7% residual activity, respectively.
研究领域:
生物技术
·
酶工程
·
纳米材料科学
✓ 已验证
产品关联
DOI
危险品化学品经营许可证（带存储）