SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2026
·
IF 4.8
Siting Zhou,Shuyi Qin,Qin Zhang,Baizhen Yuan,Yan Pang,Jiali Liang,Jinqiu Yang,Hai-Bo Liu,Jing Wang
The increasing environmental contamination by tetracycline antibiotics (TCs) necessitates efficient detection and removal strategies. This study presents the development of a bifunctional material, Eu-NU-1000, which integrates ratiometric fluorescence detection and high-capacity adsorption of TCs. The material is constructed by doping europium ions (Eu 3+ ) into the zirconium-based metal-organic framework (MOF) NU-1000, offering a dual-channel fluorescence response for selective TCs detection and enhanced adsorption performance. Eu-NU-1000 enables highly sensitive and selective detection of TCs through ratiometric fluorescence at 617 and 472 nm, the detection mechanism was based on antenna effect and photoinduced electron transfer, with a low limit of detection (LOD): 22.14 nM for tetracycline and 11.83 nM for oxytetracycline. Furthermore, the material exhibits a high adsorption capacity of 440.6 mg·g −1 for tetracycline, surpassing several existing MOF-based adsorbents. The study also investigates the adsorption mechanisms, including electrostatic interactions, coordination chelation, and π-π stacking, which collectively contribute to the exceptional tetracyclin removal efficiency of Eu-NU-1000. The material maintains over 80% adsorption efficiency after five regeneration cycles, highlighting its reusability and practical applicability in environmental remediation.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
·
IF 5.4
Chenxi Wang,Mantang Liu,Haonan Zeng,Guangming Tian,Dong Yang,Jianhua Ma
The real-time monitoring of the wound microenvironment, coupled with on-demand and precise drug release, presents a key challenge in the development of next-generation smart dressings. Conventional dressings are often inadequate for addressing the complex pathological environment of chronic wounds. Herein, we designed and constructed a core-sheath fiber integrating environmental sensing, fluorescent signal feedback, and enzyme-responsive drug delivery. This was achieved through an integrated fabrication strategy combining wet spinning, dip-coating, and photocuring. The core, an interpenetrating polymer network (IPN) of europium-crosslinked sodium alginate and sodium polyacrylate (Eu@SA/PAAS), functions as the fluorescent sensing component. Leveraging the coordination chemistry of Eu 3 + , the core exhibits a dual fluorescence response to pH and Fe 3+ . The high concentration of Fe 3+ during hemostasis leads to fluorescence quenching, whereas the alkaline milieu of the inflammatory phase triggers stable red emission. This mechanism enables visual, real-time monitoring of the wound healing process. The therapeutic function is imparted by the sheath layer, composed of photo-cured methacryloyl gelatin (GelMA) loaded with ceftriaxone sodium (CEFNa). This layer undergoes specific enzymatic degradation by matrix metalloproteinase-9 (MMP-9), which is overexpressed in chronic wounds, thereby triggering the on-demand release of the antibiotic. Consequently, the released CEFNa demonstrated potent antibacterial activity against E. coli , S. aureus , and P. aeruginosa , with inhibition zone radii of 6 ± 0.3 mm, 8 ± 0.4 mm, and 9 ± 0.4 mm, respectively. This core-sheath architecture establishes an autonomous closed-loop system of “microenvironment sensing → fluorescent feedback → enzyme-triggered drug release,” offering a novel strategy for the intelligent and personalized management of chronic wounds.
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RSC Advances
·
2026
·Vol. 16
·期 2
·1322-1334
·
IF 4.6
Ruipeng Guo,Sujiao He,Bing Zhu,Zhiwen Xi,Jiaxin Wang,Mingsha Jie
Tetracycline (TC) residues in animal-derived foods pose potential risks to human health; thus, the establishment of detection methods with high accuracy, strong sensitivity, and easy operation is of considerable importance. Within the present work, a dual-emission fluorescent probe derived from a dual-ligand europium-based MOF (NH2-BDC-Eu-DPA) was developed and thereafter integrated into a fluorescent hydrogel to enable the rapid detection of TCs in animal-derived foods. The probe uses Eu3+ as the metal node, with 2-aminoterephthalic acid (BDC-NH2) and pyridine-2,6-dicarboxylic acid (DPA) as dual ligands. Upon excitation at 260 nm, it exhibits dual fluorescence peaks at 427 nm and 617 nm. TCs can specifically quench the fluorescence at these two wavelengths through the IFE, and the quenching effect at 427 nm is more significant. Quantitative analysis is achieved based on the fluorescence intensity ratio (F427/F617). After optimizing the experimental conditions, this method exhibits a linear detection range of 1–200 µmol L−1 for doxycycline hydrochloride (DOX), tetracycline (TC), and oxytetracycline (OTC), with a limit of detection of 31.0 nmol L−1, 29.7 nmol L−1, 35.1 nmol L−1, respectively. In actual sample detection, the spiked recoveries for milk and pork are 91.0–106.8% and 89.7–106.4%, respectively, with a relative standard deviation (RSD) ≤ 6.5%. Furthermore, as the concentration of TCs increases, the intensity of the purple fluorescence emitted by the hydrogel shows a gradual downward trend, showing a good linear relationship. The method possesses high selectivity, anti-interference capability, and rapid response characteristics, providing reliable technical support for on-site monitoring of TC residues in animal-derived foods.
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RSC Advances
·
2021
·Vol. 11
·期 34
·21073-21083
·
IF 3.361
Yi Qian,Jinying Zheng,Long Li,Peng Qiao,Ying Li,Yinghui Duan,Guozhang Chang
In this paper, a certain amount of rare earth (europium) was doped into magnesium aluminum salt solution and assembled with graphene oxide (GO) by electrostatic interaction under alkaline conditions. Then, the EuMgAl-LDH/GO hybrid material was synthesized by a hydrothermal method. Its microstructure was analyzed and tested by X-ray diffraction (XRD), energy dispersive spectrometry (EDS), transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR), the results indicated that the EuMgAl-LDH/GO hybrid material had been successfully prepared. Next, it was mixed with zinc borate and added to a thermoplastic polyurethane (TPU) (thermoplastic polyurethane) matrix by melting blending. The flame retardant and smoke suppression effect of the composite was tested by conical calorimetry. The results showed that, compared with simple TPU, the PHRR (peak heat release rate), THR (total heat release), PSPR (peak smoke production rate) and TSP (total smoke production) value of the composite material decreased by 65.6%, 16.2%, 61% and 37.1%, respectively. Finally, through analysis of the carbon residue after combustion of the TPU composite material, we found that the formed carbon layer is denser and the char yield is greatly improved.
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CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Yibiao Zou,Fei Sun,Chengmei Liu,Chunhan Yu,Mojue Zhang,Qianyuan He,Yuxuan Xiong,Zushun Xu,Shengli Yang,Guangfu Liao
A simple method is presented for the preparation of novel europium complexes-grafted-oxidative dopamine (ECOD) nanoparticles with uniform sizes (ca. 220 nm), as a high-performance nanotheranostic agent guided by X-ray computed tomography (CT) and photoluminescence (PL). Here, an oxidative dopamine precursor with a rough surface is first prepared by copper (II) ionic catalysis. Then, europium complexes are successfully grafted onto the oxidative dopamine precursor by surface-initiated atom transfer radical polymerization (ATRP). Interestingly, as the additional amount of europium (III) complexes increases, the roughening extent of the ECOD nanoparticles is increased, and the roughening surface expands to a porous network structure. This nanoagent with a rough surface exhibits not only excellent X-ray attenuation properties, but also prominent eminent near-infrared (NIR) absorbance and strong optical imaging efficiency. In addition, ECOD can provide an effective photothermal therapy (PTT) effect, and 39% photothermal conversion efficiency can be achieved. Furthermore, there is no widely detectable toxicity induced in vivo/vitro , and blood circulation can last for a long time in the presence of ECOD nanoparticles, leading to efficient accumulation at the tumor site by a persistently of enhanced permeability and retention (EPR) effect. With the combination of NIR laser irradiation (1.5 W/cm 2 ) for 10 min at 808 nm, effective photothermal ablation of a tumor in vivo can be achieved. Thus, ECOD nanoparticles can be used for effective antitumor treatment and may further exhibit potential as a nanotheranostic agent for clinical diagnosis and treatment.
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Nanoscale
·
2018
·Vol. 10
·期 15
·7163-7170
·
IF 7.233
Jiahui Zhao,Shuang Wang,Shasha Lu,Jian Sun,Xiurong Yang
As a ubiquitous hydrolysis enzyme in phosphate metabolism, alkaline phosphatase (ALP) is a significant biomarker in laboratory research and clinic diagnosis. Herein, we report a highly water-soluble Eu(DPA)3@Lap nanohybrid material for the rapid and selective assay of PPi and ALP through a luminescence off–on recognition process. Eu(DPA)3@Lap was successfully prepared in an aqueous solution, and it exhibited strong luminescence emission, high photostability, and long lifetime. More interestingly, the strong luminescence of Eu(DPA)3@Lap can be remarkably quenched by Cu2+ due to the high impetus of coordination between the DPA ligand and Cu2+ ion. Using Cu2+ as a signal transducer, the luminescence could be recovered upon the addition of PPi ion owing to the formation of a Cu2+–PPi complex; thus, a luminescence turn-on assay for PPi ions was realized. Utilizing the ability of Cu2+ to differentiate between PPi and Pi, a convenient and straightforward luminescence assay for ALP activity was accomplished based on the specific dephosphorylation of PPi to Pi. To the best of our knowledge, this elaborate luminescence sensing system constitutes the first luminescent nanohybrid material based on a europium organic complex for ALP activity assay. Furthermore, the recognition process of PPi and ALP was completed in a convenient and facile mix-and-readout manner, and it revealed significant potential in point of care testing.
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POLYHEDRON
·
2014
·
IF 2.047
Tianzhi Yu,Ruizhi Liang,Yuling Zhao,Yalu Song,Bin Gao,Minghao Li,Luofu Min,Hui Zhang,Duowang Fan
Lanthanide complexes of the form Ln(DBM) 3 (Cz-PBM) (where Ln = Gd(III), Tb(III) and Eu(III); DBM = dibenzoylmethane and Cz-PBM = (4-(9 H -carbazol-9-yl)phenyl)methyl-2-(2′-pyridyl)benzimidazole) have been successfully synthesized and characterized. The crystal structures of the Gd(III) and Tb(III) complexes were determined by single-crystal X-ray analysis. The results reveal that in the complexes the central metal ions assume a square antiprismatic geometry and are octa-coordinated by six oxygen atoms from DBM ligands and two nitrogen atoms from the Cz-PBM ligand. Under excitation with ultraviolet light, the Eu(III) complex exhibited a strong red emission, but the Tb(III) complex did not show the characteristic emissions of the Tb 3+ ion. The results show that the ligands favor energy transfers to the emitting energy level of Eu 3+ .
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DYES AND PIGMENTS
·
2014
·
IF 3.468
Xia Kong,Qi Jia,Fanghua Wu,Yanli Chen
A new sandwich-type bis(phthalocyaninato) europium complex [Pc(OAr) 8 ]Eu[Pc(OAr) 8 ] [Pc(OAr) 8 = 2,3,9,10,16,17,23,24-octanaphthoxy phthalocyanine], was synthesized and fabricated into organic field-effect transistors devices on a flexible plastic substrate by using a simple solution-based quasi–Langmuir–Shäfer method. Ambipolar transport has been obtained in [Pc(OAr) 8 ]Eu[Pc(OAr) 8 ]-based thin film transistors with the carrier mobilities to 0.10 cm 2 V −1 s −1 for holes and 0.01 cm 2 V −1 s −1 for electrons, respectively. The energy levels of the highest occupied molecular orbital (−4.63 eV) and the lowest unoccupied molecular orbital (−3.41 eV) were obtained based on electrochemical studies of this double-decker complex. These values just simultaneously meet the energy levels required for p -type and n -type natures of organic semiconductors , suggesting the ambipolar organic semiconducting nature of this double-decker complex. Organized film microstructures and J -type molecular stacking mode for the double-decker complex in the quasi–Langmuir–Shäfer film are revealed. This study constitutes the first attempt to fabricate low-cost, flexible ambipolar phthalocyanine-based organic field-effect transistors by using simple solution-processing methods.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2017
·
IF 3.359
Xin Lu,Dongxiang Zhang,Shengnan He,Jian Feng,Alemtsehay Tesfay Reda,Cong Liu,Zhi Yang,Lei Shi,Jinying Li
In this paper, extraction behaviors of different carboxylic acid modified calixarenes towards Eu(III) and Nd(III) were performed. These extractants were extensively evaluated for the extraction abilities for extraction of Eu(III) and Nd(III) under different conditions, including pH, concentration of extractants and temperature. Carboxylic acid modified calix[6]arene (extractant- 2 ) showed remarkably high extraction ability for Eu(III) and Nd(III). The thermodynamic parameters (enthalpy, entropy and Gibbs free energy) were determined. The extraction of Eu(III) with extractant- 2 occurred with a cation exchange reaction and this extraction reaction is an exothermic process. Kinetic studies of reactive extraction of Eu(III) with extractant- 2 were performed in a stirred cell. The value of mass-transfer coefficient of Eu(III) in chloroform was evaluated to be 3.35 × 10 −6 m s −1 . The Hatta number was calculated and observed to vary in the range of 3.80 × 10 −4 –9.10 × 10 −4 . The effects of stirring speed, the phase volume ratio and species concentration on the initial extraction rate and Hatta number, demonstrate that the reaction is a very slow chemical reaction process occurring at the bulk of the organic phase. The rate constants of forward and backward reactions were determined to be 3.05 × 10 −2 (kmol m −3 ) −0.64 s −1 and 1.55 × 10 −3 (kmol m −3 ) −2.64 s −1 , respectively.
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OPTICAL MATERIALS
·
2016
·
IF 2.183
Muhua Chen,Yuhui Zheng,Jinwei Gao,Qianming Wang
A new type of Eu(III)-gatifloxacin complex with characteristic red luminescence has been prepared. Due to the presence of ionization effect linked to the organic chromophore , the molecular fluorescent sensor demonstrated variable pH-sensitive absorption and emission curves. The red emission derived from europium ions was strong during pH range 8–10. Between pH = 7 and 4, the europium emission remained relatively stable and fluorescence signals of gatifloxacin has been improved substantially. Under acidic conditions (pH = 1 to 3), the dramatic changes in the emission colors (from red, yellow to green) were clearly observed. Moreover, the excitation wavelength can be extended into the visible light range (Ex = 411 nm) by using the concentration effect experiment. Importantly, it gave turn- off emissions in the presence of Cu 2+ or Fe 3+ and the detection limits were determined to be 6.5 μM for Cu 2+ and 6.2 μM for Fe 3+ respectively.
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ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Li Li,Lin-Lin Zhang,Jin Zou,Jiamin Zou,Lu-Ying Duan,Yansha Gao,Guanwei Peng,Xigen Huang,Limin Lu
Background Lanthanide metal-organic frameworks (Ln-MOFs) are a kind of emerging crystalline porous materials with high fluorescence and easy-to-tunable properties, making them ideal for sensing applications. However, current Ln-MOFs based fluorescent probes are primarily single-emissive or fluorescence-quenched, which greatly limited the detection performances such as sensitivity, accuracy and repeatability, thereby hindering their applications in efficient target monitoring and related disease diagnosis. To address these issues, the reasonable design of Ln-MOFs equipped with dual fluorescence emissions and light-up mode is urgently needed for a high-performance biosensor . Results A dual-emissive europium doped UiO-66 (Eu@UiO-66-NH 2 -PMA)-based ratiometric fluorescent biosensing platform was constructed for highly sensitive and selective detection of the histidinemia biomarker-histidine (His). Eu@UiO-66-NH 2 -PMA (pyromellitic acid abbreviated as PMA) was synthesized utilizing a post-synthetic modification method via coordination interactions between the free –COOH of UiO-66-NH 2 -PMA and Eu 3+ , which exhibited characteristic peaks of broad ligand emission and sharp Eu 3+ emissions simultaneously. Considering that Cu 2+ had the excellent fluorescence quenching ability toward Eu 3+ and superior affinity with His, it was deliberately introduced into the Eu@UiO-66-NH 2 -PMA, acting as active sites for target His responsiveness. The Eu@UiO-66-NH 2 -PMA/Cu 2+ /His ternary competition system demonstrated a low detection limit of 74 nM, excellent selectivity and good anti-interference capability that allowed for sensitive analysis of His levels in milk and human serum samples. Significance Attributing to the superior luminescent properties, good stability and self-calibration capability of Eu@UiO-66-NH 2 -PMA, the developed ratiometric light-up sensing platform enabled sensitive, selective and credible analysis of His in complex practical samples, which might provide an available tool for food nutrition guideline and diagnostic applications of His related diseases.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 4
·1-12
·
IF 5.3
Zhou Xiayu,Wang Yue,Song Jiayi,Xiong Lihao,Zhao Xin,Chen Sihan,Zhao Weichao,Li Le,Zhen Deshuai
Three types of carbon dots were synthesized using the same precursor (folic acid and europium nitrate) via different preparation methods (doping and direct coordination). A comprehensive comparison and analysis of the morphology, surface groups, and optical properties of the prepared carbon dots (CD), europium-doped carbon dots (CD-Eu), and europium-functionalized carbon dots (CD@Eu) were conducted. Moreover, due to the higher quantum yield, excellent stability, and outstanding selectivity for UO 2 2+ exhibited by CD-Eu, we selected CD-Eu as the probe for subsequent applications. CD-Eu showed a sensitive response to UO 2 2+ within the concentration range 25 ~ 200 nM, with a detection limit of 0.84 nM (0.42 μg·L −1 ). Additionally, CD-Eu demonstrated excellent accuracy and recovery in spiked detection of real water samples. Furthermore, we discovered that this probe could detect UO 2 2+ both in vitro and in viv o. This strategy provides a promising fluorescent sensor for the detection of UO 2 2+ in water and biological samples, holding significant implications for addressing UO 2 2+ contamination issues. Graphical abstract
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危险品化学品经营许可证（带存储）