SENSORS
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2023
·Vol. 23
·期 11
·5218
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IF 3.9
Huiji Chen,Binbin Luo,Shengxi Wu,Shenghui Shi,Qin Dai,Zehua Peng,Mingfu Zhao
Simple SummaryA microfluidic biosensor based on a thin-core microfiber coated with molybdenum disulfide for immune detection ofToxoplasma gondiiwas illustrated. The detection range, limit of detection, detection sensitivity, specificity, and clinical properties of the proposed biosensor were explored.AbstractToxoplasma gondii(T. gondii) is a zoonotic parasite that is widely distributed and seriously endangers public health and human health. Therefore, accurate and effective detection ofT. gondiiis crucial. This study proposes a microfluidic biosensor using a thin-core microfiber (TCMF) coated with molybdenum disulfide (MoS2) for immune detection ofT. gondii. The single-mode fiber was fused with the thin-core fiber, and the TCMF was obtained by arc discharging and flame heating. In order to avoid interference and protect the sensing structure, the TCMF was encapsulated in the microfluidic chip. MoS2andT. gondiiantigen were modified on the surface of TCMF for the immune detection ofT. gondii. Experimental results showed that the detection range of the proposed biosensor forT. gondiimonoclonal antibody solutions was 1 pg/mL to 10 ng/mL with sensitivity of 3.358 nm/log(mg/mL); the detection of limit was calculated to be 87 fg/mL through the Langmuir model; the dissociation constant and the affinity constant were calculated to be about 5.79 × 10−13M and 1.727 × 1014M−1, respectively. The specificity and clinical characteristics of the biosensor was explored. The rabies virus, pseudorabies virus, andT. gondiiserum were used to confirm the excellent specificity and clinical characteristics of the biosensor, indicating that the proposed biosensor has great application potential in the biomedical field.Keywords:thin-core microfiber;microfluidic chip;molybdenum disulfide;optical fiber biosensor;toxoplasma gondii
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
·
IF 8.2
Qiang Yao,Jing Guo,Fucheng Guan,Jia Li,Da Bao,Jiahao He,Xinbin Ji,Xuecui Song,Qiang Yang
In order to improve the adsorption performance of MoS 2 , as well as to solve the problems of MoS 2 -powder in adsorption, which is prone to agglomeration and difficulty to be recycled, we prepared MoS 2 -nanoflowers(MoS 2 -NFs), and mixed them with sodium alginate/polyvinyl alcohol(SA/PVA) to prepare MoS 2 -NFs/SA/PVA xerogel(MSP) by freezing-lyophilization. Then two forms of xerogels - block-MSP(MSPB) and spherical-MSP(MSPS) were prepared, and they were used as methylene blue(MB) and Cu 2+ adsorbent. It was found that MoS 2 -NFs were evenly dispersed inside the SA/PVA with no agglomeration, while the interior of MSPB/MSPS showed the structure of parallel-pores and radial-pores, respectively. The adsorption capacity of MSPB/MSPS on MB can reach 233 mg/g, which is five times higher than SA/PVA-gel, showing excellent synergistic-adsorption effect, and the adsorption capacity for Cu 2+ reaches 271 mg/g. The adsorption mechanism indicated that the adsorption of MB by MSPB/MSPS conformed to pseudo-first-order model, with electrostatic force as the main force. And their adsorption of Cu 2+ conformed to pseudo-second-order model and was dominated by Lewis acid/base soft-soft interactions. Notably, after long-term adsorption, MSPB/MSPS maintains its shape and more than 90 % of the adsorption capacity, ensuring the recovery and reuse of materials. So, MSPB/MSPS has great potential in adsorption, providing a new solution for sewage purification .
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POLYMER TESTING
·
2023
·
IF 5.1
Changhua Yang,Hengtong Zhang,Renqiang Yang,Pengfei Ma,Yuansen Liu,Min Nie
Interventional catheter is the essential assembly part of interventional therapy. Confronted with complex channels, the catheter suffers from weak mechanical property, high catheter-tissue friction and inferior biocompatibility. Herein, the robust mechanical, lubricated and biocompatible molybdenum disulfide (MoS 2 )/polypropylene (PPR) catheter was fabricated via flow-directed preferential alignment and fluorination treatment. By rotating the mandrel and die, a dual-directional flow field was constructed and the two-dimensional MoS 2 plates aligned preferentially with the planar surface perpendicular to the radial direction of the catheter. Benefiting from the preferential alignment of MoS 2 plates, the tensile strength of the rotationally-extruded MoS 2 /PPR catheter increased by 25.1% compared to the pristine PPR catheter. Furthermore, the direct fluorination treatment was applied to endow the optimized tribology performance and biocompatibility. As a result, the MoS 2 /PPR catheter with excellent comprehensive performance was prepared by bulk morphology and surface manipulation strategy, which was suitable for industrial scale preparation.
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ACS Applied Energy Materials
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2023
·
IF 6.4
Xiaoxiao Cheng,Yun Tong
Structural engineering of the molybdenum disulfide (MoS2) retains its importance for the application of the hydrogen evolution reaction (HER) in a full pH range. However, the catalytic performance of reported MoS2-based materials, especially in neutral conditions, is unsatisfactory. Herein, an effective synergy between CoP, Ni2P, and MoS2 nanosheets is established via a simple strategy, which constructs a self-supporting (CoP/Ni2P/MoS2–CC) electrode endowed with abundant catalytic active sites, optimal electronic structure, and improved charge transfer capability. The optimized CoP/Ni2P/MoS2–CC sample shows low overpotentials of 335, 119, and 211 mV at 100 mA cm–2 in neutral, alkaline, and acidic electrolytes with small Tafel slopes of 63, 62, and 82 mV dec–1, respectively. Remarkably, the catalytic performance in neutral medium is superior to that of most of the reported MoS2-based hybrid electrocatalysts. Our work proves a facile and feasible strategy to promote the pH-universal catalytic activities of MoS2-based heterogeneous structures for hydrogen production.
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JOURNAL OF HAZARDOUS MATERIALS
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2020
·
IF 9.038
Yadong Li,Yingliang Liu,Desong Yang,Qian Jin,Cailan Wu,Jianghu Cui
Molybdenum disulfide sheets loaded with copper nanoparticles (MoS 2 -CuNPs) was prepared and its antibacterial activity against phytopathogen Xanthomonas oryzae pv. oryzae (Xoo) was investigated in vitro and in vivo for the first time. In a 2 h co-incubation, MoS 2 -CuNPs exhibited 19.2 times higher antibacterial activity against Xoo cells than a commercial copper bactericide (Kocide 3000). In the detached leaf experiment, the disease severity decreased from 86.25 % to 7.5 % in the MoS 2 -CuNPs treated rice leaves. The results further demonstrated that foliar application of MoS 2 -CuNPs could form a protective film and increase the density of trichome on the surface of rice leaves, finally prevent the infection of Xoo cells. This was probably due to the synergistic effect of MoS 2 -CuNPs. Additionally, foliar application of MoS 2 -CuNPs (4−32 μg/mL) increased obviously the content of Mo and chlorophyll (up 30.85 %), and then improved the growth of rice seedlings. Furthermore, the obtained MoS 2 -CuNPs could activate the activities of the antioxidant enzymes in rice, indicating higher resistance of rice under abiotic/biotic stresses. The multifunctional MoS 2 -CuNPs with superior antibacterial activity provided a promising alternative to the traditional antibacterial agents and had great potential in plant protection.
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SCIENCE OF THE TOTAL ENVIRONMENT
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2020
·
IF 6.551
Hongwei Luo,Ying Cheng,Yifeng Zeng,Kai Luo,Xiangliang Pan
Accelerating the rate-limiting step of Fe 3+ /Fe 2+ conversion is a major challenge for H 2 O 2 decomposition in conventional Fenton process. In this study, the catalytic mechanism of H 2 O 2 by molybdenum disulfide (MoS 2 ) nanoparticles and Fe 3+ ions was revealed and the abatement of organic micropollutants was investigated. The presence of both MoS 2 and Fe 3+ can efficiently decompose H 2 O 2 . Reaction system of H 2 O 2 /MoS 2 /Fe 3+ is found to remove most of the tested pollutants by over 80% (except 65.9% for carbamazepine) within 60 min at pH of 3.0. Effective pH range of this reaction system can be extended to pH of 5.0. Adding MoS 2 to Fe 3+ /H 2 O 2 system promotes the Fe 3+ /Fe 2+ cycle and improves the reaction rate between Fe 3+ and H 2 O 2 . The formation of Mo 6+ ions and Mo 6+ peroxo-complexes is beneficial to H 2 O 2 decomposition and pollutant degradation . Electron paramagnetic resonance (EPR) measurements and quenching experiments confirm the important role of hydroxyl radicals in H 2 O 2 /MoS 2 /Fe 3+ system. Chloride ions (Cl − ) promote degradation, while bicarbonate ions (HCO 3 − ) inhibit degradation. As H 2 O 2 concentration increases from nil to 1.0 mM, the value of total EE/O decreases from 0.083 to 0.003 kWh L −1 , and the most energy efficient condition is determined. This study provides a new pathway for efficient decomposition of H 2 O 2 by Fe 3+ ions in an extended pH range, which is considered a facile and promising strategy for wastewater treatment .
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JOURNAL OF ALLOYS AND COMPOUNDS
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2019
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IF 4.175
Fan Yang,Zhanfang Cao,Jing Wang,Shuai Wang,Hong Zhong
In this work, in situ growth of thin layer and highly catalytic activity molybdenum disulfide (MoS 2 ) was successfully synthesized by spatial confinement effect of Mg–Al layered double hydroxide (Simplified as LDH below). Due to the unique spatial confinement effect and electropositivity of the LDH layer, MoS 2 will controllable in situ grows along the surface of LDH layer, the MoS 2 synthesized in LDH tends to monolayer or thin layer instead of growing into a flower-like structure, this new strategy is different from vapor deposition, exfoliation and laser irradiation to prepare thin layer MoS 2 . Meanwhile, the conglomerate structure of LDH is opened and converted to thin layer by the growth of MoS 2 , too. The rich defects carried by thin layer LDH also help to improve the catalytic ability of MoS 2 . MoS 2 /LDH can absorb the light from ultraviolet to visible light region, The prepared MoS 2 /LDH composite was used as a photocatalytic material, and was found to be the best photocatalyst degrading about 96% of the MB solution (20 mg/L) after 180 min.
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COMPOSITES SCIENCE AND TECHNOLOGY
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2016
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IF 3.897
Xiaming Feng,Weiyi Xing,Jiajia Liu,Shuilai Qiu,Yuan Hu,Kim Meow Liew
Molybdenum disulfide (MoS 2 ) nanosheets were non-covalently organo-modified by electrostatically interacting with cetylpyridinium chloride (CPC) and then were used to reinforce the properties of polyurethane acrylate (PUA) resin for the first time. Benefited from the alkyl chain of CPC, the modified MoS 2 nanosheets can be well dispersed in PUA matrix. Notably, inclusion of 0.5 wt% CPC-MoS 2 leads to a 11.7 °C increase in the temperature corresponding to 50 wt % weight loss, indicating the enhanced thermal stability of PUA nanocomposites . Moreover, the improvement in tensile strength , work of fracture and storage modulus (at −75 °C) of PUA/f-MoS 2 nanocomposites can reach up to 37.4%, 41.9% and 102.0% respectively. This substantial nano-reinforcement is mainly attributed to the proper organic modification and inherent feature of MoS 2 nanosheets. The strong interfacial adhesion within PUA/f-MoS 2 nanocomposites can efficiently transfer the load from weak polymer chains to robust MoS 2 nanosheets.
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ANALYST
·
2018
·Vol. 143
·期 7
·1644-1649
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IF 3.864
Girma Selale Geleta,Zhen Zhao,Zhenxin Wang
In this study, we developed a novel reduced graphene oxide/molybdenum disulfide/polyaniline@gold nanoparticles-based electrochemical aptasensor (termed as RGO/MoS2/PANI@AuNPs/Apt) for detection of aflatoxin B1 (AFB1). The RGO/MoS2/PANI nanocomposites were synthesized and characterized by multiple techniques, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), infrared spectroscopy (FTIR), UV-visible spectroscopy, and X-ray photoelectron spectroscopy (XPS). A glassy carbon electrode (GCE) was then modified by the RGO/MoS2/PANI nanocomposites, coated with a chitosan (Cs) film, and followed by AuNPs attachment for immobilizing the AFB1 aptamers. In the presence of AFB1, the AFB1 binding-induced conformation change of the immobilized aptamer on the electrode surface results in the reduction of the electron transfer from a [Fe(CN)6]3−/4− redox couple in the solution to the GCE surface. Therefore, the aptamer-AFB1 binding event can be easily monitored by the peak current change of the RGO/MoS2/PANI@AuNPs/Apt through differential pulse voltammetry (DPV) measurement. Under the optimized conditions, the as-developed RGO/MoS2/PANI@AuNPs/Apt exhibits a wide linear range from 0.01 fg mL−1 to 1.0 fg mL−1 and a remarkably low detection limit (3σ) of 0.002 fg mL−1. The aptasensor also has good reproducibility as well as shows high selectivity against other fungal toxins, such as OTA and FB1. Moreover, the practicability of the RGO/MoS2/PANI@AuNPs/Apt was demonstrated by the analysis of AFB1 in the spiked wine samples.
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TALANTA
·
2019
·
IF 4.916
Ankita Sinha,Yujin Huang,Huimin Zhao
The present work reports development of advanced nanosensor platform based on hierarchical 3D nanotubes assembled from MoS 2 mono layers (3D MoS 2 NTs) for rapid and selective screening of well known carbamate fungicide, diethofencarb . The assembly of ultrathin MoS 2 layers possessed mesopores and large specific surface area which enabled its potential implementation in electrode fabrication. Preparation of 3D MoS 2 NTs helped to avoid restacking and aggregation during its utilization as sensor material and manifested great sensing abilities towards electro-oxidation of diethofencarb. The LOD and LOQ for diethofencarb at 3D MoS 2 NTs/GCE were calculated as 0.32 ng μL −1 and 1.09 ng μL −1 in the concentration range of 1–55 ng μL −1 by square wave voltammetry (SWV) and further 0.63 ng μL −1 and 2.11 ng μL −1 in the concentration range of 1–35 ng μL −1 by differential pulse voltammetry (DPV). The developed 3D MoS 2 NTs nanosensor was successfully used to quantify diethofencarb in river water sample with satisfied recovery of 94.23%–105.46% justifying its analytical utility in pesticide screening. The study drives immense motivation towards sensing of hazardous pesticides using nanomaterials based advanced sensing devices for environmental monitoring.
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Materials Science & Engineering C-Materials for Biological Applications
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2018
·
IF 5.08
Weiwei Zhang,Zhipeng Mou,Yazhe Wang,Ying Chen,Endong Yang,Feng Guo,Dongdong Sun,Weiyun Wang
A method was developed for the liquid exfoliation of molybdenum disulfide (MoS 2 ) from its bulk materials using ultrasound in aqueous phase with the assistance of chitosan (CS) and silver nanoparticles (Ag NPs) for effective loading of a variety of therapeutic molecules. The characterization results revealed that the as-made chemically-exfoliated MoS 2 nanosheets had an average thickness of ∼10 nm. The new material, CS and Ag NPs-modified MoS 2 (MoS 2 -CS-Ag), showed highly effective antifungal activities against Saccharomyces uvarum and Aspergillus niger . The Ag NPs-loaded MoS 2 nanosheets achieved outstanding antifungal effect by inhibiting fungal growth both in vitro and in vivo . Notably, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analysis of spore morphological changes caused by MoS 2 -CS-Ag treatment reveal that it may directly cause the cell death. The result of the analysis of the application of MoS 2 -CS-Ag as an antifungal for fruits also demonstrated the MoS 2 -CS-Ag protective properties against fungi. The excellent film-forming ability of CS has been shown to contribute to the effectiveness of MoS 2 -CS-Ag in preserving the freshness of fruits, exhibited in four chemical quality sections: Vc, total carbohydrate, weight loss, and titratable acidity in fruit preservation application assay. The present study reports a new and exciting insight in a multi-functional drug carrier for protecting postharvest fruit.
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 9
·1-9
·
IF 6.232
Song Yiju,Qiao Jingwen,Li Wenjun,Ma Chaoyun,Chen Siyu,Li Hongling,Hong Chenglin
A molybdenum disulfide based graphite phase carbon nitride (MoS 2 /g-C 3 N 4 ) which is supported by a platinum-copper nanoparticle (PtCu) Z-type catalyst was created in this study. The catalyst exploits optoelectronic synergistic effect with large surface area, good catalysis, and biocompatibility to amplify the signal. The electrode impedance of the synthesized MoS 2 /g-C 3 N 4 -PtCu was reduced five times in visible light compared with dark conditions, thereby improving the detection of carcinoembryonic antigen (CEA). At a voltage of − 0.4 V, the immunoprobe constructed with this material is used for CEA detection. A linear relationship between 100 fg mL −1 and 80 ng mL −1 concentrations was achieved with a minimum detection limit of 33 fg mL −1 (S/ N = 3). The recovery rate was 103–104%, and the relative standard deviation was 2.9–3.8%. This implies that the sandwich immunosensors have good reproducibility, selectivity, and stability and can be used in various applications.
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