MICROCHEMICAL JOURNAL
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2026
·
IF 5.1
Lanlan Wei,Yilan Zhao,Yaoye Chen,Ke Huang,Xiaoli Xiong,Qing Yang
A dual-emission CDs@Eu-DPA composite was rapidly synthesized via dielectric barrier discharge microplasma technology using carbon dots (CDs), 2,6-dipicolinic acid (DPA), and Eu 3+ as precursors. CDs@Eu-DPA was subsequently applied for ratiometric fluorescence and visual analysis of oxytetracycline (OTC) in food samples. When OTC was introduced, the blue fluorescence of CDs was quenched via the inner filter effect, while OTC coordinated with Eu 3+ in Eu-DPA to form a complex, leading to the enhancement of the red fluorescence of Eu 3+ at 615 nm through antenna effect. Additionally, principal component analysis was employed to distinguish four different antibiotics, including OTC, chlortetracycline, tetracycline, and doxycycline. Under optimized conditions, the ratiometric fluorescence analysis and smartphone-assisted RGB analysis exhibited linear detection ranges of 0.05–210.0 μM and 0.3–90.0 μM for OTC, respectively, with limits of detection of 0.02 μM and 0.08 μM, respectively. The satisfactory recoveries in food samples were ultimately achieved through the dual-mode sensing method.
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WATER AIR AND SOIL POLLUTION
·
2026
·Vol. 237
·期 11
·646
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IF 3.5
Xiao Yongbo,Gao Yanjiao,Bai Fan,Xiao Jing
The increasing contamination of aquatic environments by antibiotics calls for efficient, economical, and environmentally sustainable remediation technologies. This study presents a zero-valent iron (ZVI)-activated periodate (IO 4 − ) advanced oxidation system for the degradation of oxytetracycline (OTC) in water. Under optimized conditions (pH = 3, ZVI = 1.64 g/L, IO 4 − = 1.97 mM), the ZVI/IO 4 − system achieved 81.16% OTC removal. Notably, coupling with UV irradiation enabled complete OTC degradation within 50 min, demonstrating substantial enhancement over the standalone system. Mechanistic investigations revealed that IO 3 • , 1 O 2 , and O 2 •− were the dominant reactive species, and three degradation pathways were proposed based on LC–MS analysis. The system exhibited excellent performance in real water matrices, achieving 78.0% and 71.9% OTC removal in tap water and lake water, respectively, along with strong tolerance to coexisting ions and humic acid. Importantly, the ZVI catalyst retained 96.4% of its initial activity after five consecutive cycles, significantly reducing operational costs and secondary pollution risks. This work provides an efficient, stable, and cost-effective treatment strategy for antibiotic-contaminated water, holding strong promise for practical engineering applications.
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APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2026
·Vol. 132
·期 3
·226
·
IF 3
Hong Khanh Trung,Dang Huu Phuc,Le Hanh Ngoc Thi,Dieu Nguyen,Duyen Ky,Nguyen Quoc Thang,Nguyen Van Cuong
This study introduces a rapid synthesis method for nitrogen-doped carbon quantum dots (N-CQDs) using microwave irradiation, with citric acid and urea serving as the carbon and nitrogen sources, respectively. The material was characterized by Fourier transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis) spectroscopy, and fluorescence spectroscopy, revealing a uniform structure, nanoscale size (4–10 nm), and excellent optical properties. N-CQDs were used as fluorescent sensors to detect Fe³⁺ ions and oxytetracycline (OTC) with high sensitivity and selectivity. The results demonstrated limits of detection (LOD) of 1.685 µM and 0.638 µM for Fe³⁺ and OTC, respectively, within linear ranges of 1–32 µM and 0.2–100 µM, respectively. The fluorescence quenching mechanism for Fe³⁺ was attributed to static quenching, whereas OTC enhanced the fluorescence via hydrogen bonding and π–π interactions. The analytical performance of the N-CQDs surpassed that of many previously reported methods, highlighting their potential for environmental sensing and antibiotic residue monitoring.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Pengfei Zhu,Shasha Zhang,Mei Liu,Ming Duan,Zhaoxin Huang,Han Lu
Herein, a novel Bi 2 WO 6 /AgBr/Ag 4 V 2 O 7 double Z-scheme heterojunction photocatalytic material was synthesized by the ultrasonic-assisted coprecipitation method. When the content of AgBr in Bi 2 WO 6 /AgBr/Ag 4 V 2 O 7 is 30 wt% and the content of Ag 4 V 2 O 7 is 1 wt%, under the optimized reaction conditions, the degradation rate of Bi 2 WO 6 /AgBr/Ag 4 V 2 O 7 to oxytetracycline (OTC) reached 88.13 % within 60 min, and the photocatalytic activity decreased only slightly after repeated use for three times, other than that, the toxicity of OTC to wheat decreased significantly after degradation. The morphology, composition, crystal structure and visible light absorption capacity of the samples are investigated by a series of characterization techniques. Furthermore, free radical capture experiment, electron paramagnetic resonance (EPR) experiment and liquid chromatography-mass spectrometry (LC-MS) were used to explore the possible photocatalytic mechanism and degradation path of OTC. The results show that the improvement of photocatalytic activity is attributed to the construction of a double Z-scheme heterojunction, which provides a more effective structural space for the separation of photogenerated e - -h + pairs. This study provides a new idea for the separation of photogenerated e - -h + pairs and broadens the response range of visible light, and proposes a new strategy for the environmental treatment of photocatalysts.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
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IF 9.965
Jing Wu,Jiabing Li,Gary Owens,Zuliang Chen
The widespread use of antibiotics, such as oxytetracycline (OTC) and levofloxacin (LEV), has led to dangerous levels of environmental contamination. In this study, functionalized iron/manganese nanoparticles (Fe/Mn NPs), which act as both adsorbent and Fenton catalyst, were green-synthesized using a reducing agent derived from a tea extract. The resulting pre-sorption/Fenton-like oxidation system effectively removed both OTC and LEV from the aqueous solution with adsorption capacities of Fe/Mn NPs for OTC and LEV of 58.8 and 192.3 mg·g −1 , respectively. In addition, Fe/Mn NPs also showed high catalytic activity, oxidizing more than 99.9 % of both OTC and LEV, while sodium persulfate (PDS) removed only 26.6 and 29.0 % of OTC and LEV, respectively. Mechanisms of PDS activation typically involve either catalyst-initiated or mediated electron transfer reactions. Fe/Mn NPs through heterogeneous catalytic and metal leaching-induced homogeneous Fenton reactions, which generated various reactive oxygen species (ROS) including 1 O 2 , ·OH, SO 4 - · and ·O 2 – . Characterization of Fe/Mn NPs before and after reaction, and the identification of specific OTC and LEV degradation products by LC-MS, helped to elucidate a potential degradation pathway, as well as the removal mechanism. Finally, the practicality of using this system for wastewater treatment was demonstrated using real wastewater samples indicating that the system has great potential for simultaneously degrading both OTC and LEV in contaminated wastewater.
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Food & Function
·
2022
·Vol. 13
·期 20
·10476-10490
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IF 6.317
Ju Wang,Lei Wang,Shengnan Shi,Yaqi Cao,Junmei Feng,Changhong Liu,Lei Zheng
Probiotic-based therapy is a promising approach, which can positively modulate bacterial composition and maintain homeostasis. However, exogenous probiotics are easily destroyed by harsh conditions in vivo; thus, their application prospects have been severely limited. Specifically, oxytetracycline (OTC), a broad-spectrum antibiotic widely used in aquaculture, results in adverse intestinal environments, such as dysbacteriosis, oxidative damage, and gut dysmotility. Here, we describe a facile method to apply glycol chitosan/alginate as armor on the surface of probiotics to effectively protect them from the changed enteric environments induced by OTC. The results demonstrated that the coated Lacticaseibacillus rhamnosus GG (LGG) for only 2 h administration could significantly improve the colonization rate of LGG, and the relative abundance of Lacticaseibacillus can reach 80% in OTC-treated larvae intestines. We also explored the specific mechanisms of the coated LGG to diminish reactive oxygen species (ROS) generation and rescue gut dysmotility for OTC treatment, including enhancing the activity of antioxidative enzymes (CAT, SOD and GPx) and increasing 5-HT synthesis. The mitigation effect of the coated LGG for 2 h administration was comparable to that of uncoated LGG for 24 h administration. Encapsulation of LGG with polysaccharides provides a unique application example for generating useful bacterial therapeutics in harsh intestinal environments.
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REACTIVE & FUNCTIONAL POLYMERS
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2022
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IF 4.966
Qian Liu,Zijie Fan,Xibin Yi,Shiwei Chen,Bing Li,Weiyue Luo
The polyimide is a promising semiconductor photocatalyst . However, its photocatalytic activity is poor because of its small specific surface area, low visible light absorption and easy recombination of photoexcited electron and hole. Herein, porous polyimide/carbon quantum dots/ZnS quantum dots material aerogel with excellent photocatalytic performance is prepared via supercritical fluid drying technology. The material aerogel has large surface area and the structure is porous network. The carbon quantum dots increase the visible light absorption of the polyimide aerogel . The ZnS quantum dots change the VB edge, CB edge and band gap of the polyimide aerogel. Both carbon quantum dots and ZnS quantum dots could improve the charge transfer and facilitate the separation of photoexcited electron and hole. The visible-light photocatalytic performance over oxytetracycline of porous polyimide/carbon quantum dots/ZnS quantum dots material aerogel is increased largely compared to pure polyimide aerogel. The photocatalytic degradation mechanism of the polyimide material aerogel is proposed. ·O 2 − and h + play the key role in the photocatalytic degradation. This work supplies an effective method to prepare visible-light photocatalytic materials.
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Sensors and Actuators Reports
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2020
·
IF 0
Yukun Yang,Wenyan Yan,Yuanyuan Guo,Xiaomin Wang,Fuyuan Zhang,Ligang Yu,Caixia Guo,Guozhen Fang
As one kind of tetracycline antibiotics, oxytetracycline (OTC) residues in animal-derived foods can do serious harm to human health. Though aptasensors for the detection of OTC are widely reported, label-free electrochemical aptasensor with low cost, simple preparation and good applicability should be further explored to meet the current urgent needs. In this study, a label-free electrochemical aptasensor for OTC determination was designed. The detection was based on specific recognition by the aptamer covalently-bound on the sensing interface via diazonium coupling reaction, which was verified by computer simulation. Experiment results showed that the differential pulse voltammetry (DPV) current response of the constructed electrochemical aptasensor was linear with the logarithm of OTC concentration in the range of 1.0 × 10 −9 g mL −1 –1.0 × 10 −4 g mL −1 (R 2 = 0.9897) with the limit of detection of 2.29 × 10 −10 g mL −1 . The proposed aptasensor indicated good selectivity, reproducibility and stability, which could be attributed to the stable modification of aptamer on the sensing interface. The OTC in the milk sample was detected by the spiked recovery method, and good results were obtained, with the recovery rate being 87.0%-99.3%. The proposed label-free electrochemical aptasensor can provide methods for low-cost, accurate and rapid detection of antibiotic residues.
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ELECTROCHIMICA ACTA
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2019
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IF 5.383
Jian Sun,Wenjing Xu,Yong Yuan,Xingwen Lu,Birthe V. Kjellerup,Zhenbo Xu,Hongguo Zhang,Yaping Zhang
Photo-bioelectrochemical fuel cell shows great potential as an environmental-friendly technology for converting solar energy and bioenergy into electricity with simultaneous wastewater treatment . The present work aims to assess the performance of an algal-bacterial biocathode photo-bioelectrochemical fuel cell (ABPBFC) operated with daily light/dark cycle for simultaneous bioelectrical power generation and high-strength nitrogen removal under oxytetracycline (OTC) stress by adding different concentrations of OTC into the biocathode. The results showed that the power generation of the ABPBFCs was significantly enhanced by the presence of OTC at all levels tested (5–50 mg/L) due to enhanced electron transfer from cathode to oxygen and nitrate mediated by degradation products of OTC, but the enhancement was not proportional to the rise in OTC concentration. The largest maximum power density of 54 mW/m 2 was achieved at 5 mg/L OTC during light period and 8.5 mW/m 2 was produced at 20 mg/L OTC during dark period, corresponding to a 1.8 and 7.5 fold increases compared to that of the ABPBFC without addition of OTC. The removal of nitrate was obviously accelerated by the addition of OTC with an initial OTC concentration lower than 20 mg/L. Increases in the concentration of OTC added to the biocathode did not result in continuous enhancement in power generation and nitrate removal due to the toxicity of OTC to biocathodic microbial community. Cathodic bioelectrochemical process enhanced photolysis of OTC, which was attributed to its contribution to basification of catholyte. The growth of some dominated genus related to biocathodic electron transfer, nitrogen removal and OTC degradation were stimulated at OTC concentrations less than 20 mg/L but inhibited at 50 mg/L, except for some OTC-resistant bacteria.
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WATER RESEARCH
·
2018
·
IF 7.051
Weifu Yan,Yunyan Guo,Yong Xiao,Shuhua Wang,Rui Ding,Jiaqi Jiang,Haiyin Gang,Han Wang,Jun Yang,Feng Zhao
Microbial fuel cell (MFC) is regarded as a promising alternative for enhancing the removal of antibiotic pollutants. In this study, oxytetracycline served as an electron donor in the anode chamber of MFCs, and after continuous operation for 330 days, the efficiency of removal of 10 mg/L oxytetracycline in MFCs increased to 99.00% in 78 h, whereas removal efficiency of only 58.26% was achieved in microbial controls. Compared to microbial controls, higher ATP concentration and persistent electrical stimulation mainly contributed to bioelectrochemical reactions more rapidly to enhance oxytetracycline removal in MFCs. In addition, the analysis of bacterial communities revealed that Eubacterium spp.—as the main functional bacterial genus responsible for oxytetracycline biodegradation—flourished starting from merely 0.00%–91.69% ± 0.27% (mean ± SD) in MFCs. High-throughput quantitative PCR showed that the normalized copy numbers of total antibiotic resistance genes (ARGs) and mobile genetic elements in MFCs were 1.7364 and 0.0065 copies/cell respectively, which were markedly lower than those in the microbial controls. Furthermore, there was no significant correlation between oxytetracycline concentration in the influent and abundance of ARGs in effluent from MFCs. Nevertheless, Tp614 , a transposase gene, was found to be enriched in both MFCs and microbial reactors, suggesting that it may be a common challenge for different biological processes for wastewater treatment . This study therefore showed a lower probability of upregulation and transmission of ARGs in MFCs when compared to a traditional anaerobic microbial treatment .
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ANALYTICAL LETTERS
·
2013
·
IF 0.965
Wenjing Lian,Su Liu,Jinghua Yu,Jie Li,Min Cui,Wei Xu,Jiadong Huang
A molecularly imprinted electrochemical sensor was fabricated based on a gold electrode modified by chitosan-multiwalled carbon nanotube composite (CS-MWCNTs) multilayer films and gold nanoparticles (AuNPs) for convenient and sensitive determination of oxytetracycline (OTC). The multilayer of CS-MWCNTs composites and AuNPs were used to augment electronic transmission and sensitivity. The molecularly imprinted polymers (MIPs) were synthesized using OTC as the template molecule and o-phenylenediamine (OPD) as the functional monomer. They were modified on a gold electrode by electropolymerization. The electrochemical behavior of OTC at the imprinted sensor was characterized by cyclic voltammetry (CV), scanning electron microscopy (SEM), and amperometry. The molecularly imprinted sensor showed high selectivity and excellent stability toward OTC. The linear range was from 3.0 × 10−8 to 8.0 × 10−5 mol/L, with a limit of detection (LOD) of 2.7 × 10−8 mol/L (S/N = 3). The developed sensor showed good recovery in spiked samples analysis.
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Environmental Science-Nano
·
2025
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IF 5.1
Taotao Lu,Xiaochen Liu,Xiaochen Peng,Yuqian Jin,Sven Frei,Jianqiang Lu,Shuangcheng Tang
Biochar-derived dissolved organic carbon (BDOC) may influence the environmental fate and behavior of tetracycline antibiotics in subsurface environments. In this study, BDOC derived from the pyrolysis of wheat straw at three distinct temperatures (300 °C, 450 °C, and 600 °C) was used to investigate its influence on the transport of oxytetracycline (OTC) through saturated quartz sand. The findings demonstrated that BDOC enhanced OTC mobility due to steric hindrance caused by organic matter accumulation, competition for retention sites between OTC and BDOC, and increased electrostatic repulsion between anionic species, including OTC⁻ ions and quartz sand. Notably, the mobility-enhancing effects of BDOC became significantly more pronounced at higher pyrolysis temperatures, likely resulting from increased organic matter deposition on sand surfaces and intensified electrostatic interactions. However, the promoting effect of BDOC on OTC transport was attenuated as pH increased from 5.0 to 9.0, which was attributed to reduced competitive deposition and steric effects caused by BDOC retention. Furthermore, cation-bridging, particularly with Cu²⁺ in the background solution, amplified BDOC’s promotion effects. These results highlight that dissolved organic carbon released from biochar exerts a notable influence on the antibiotics' mobility within the aquifers.
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