Water
·
2024
·Vol. 16
·期 17
·2389
·
IF 3
Yuli Chen,Dechong Ma,Guowen He,Sai Pan
In this study, fusiform bismuth (Bi) was synthesized, and its photocatalytic performance, degradation mechanism, and pathways for removing rhodamine B (RhB) at different pH levels were investigated. Additionally, the morphologies, structural characteristics, surface electronic states, optical properties, active species, and potential degradation pathways of RhB over the fusiform Bi were analyzed. The comparison of the results before and after RhB degradation using the fusiform Bi revealed the formation of a Bi/BiOCl heterojunction photocatalyst. At pH 2.0, 3.0, 5.0, 7.0, and 9.0, the heterojunction exhibited excellent photocatalytic activity, with RhB removal efficiencies of ~97%, 96.7%, 72.6%, 53.5%, and 27.6%, respectively. Moreover, total organic carbon and chemical oxygen demand analyses were performed to evaluate the mineralization rates of RhB with the fusiform Bi at pH 3.0 and 7.0. Furthermore, the effects of catalyst content, initial RhB concentration, light source distance, inorganic anions, and reactant temperature on the photocatalytic performance of the fusiform Bi were investigated. Additionally, the types of active species and potential photocatalytic mechanisms for RhB degradation over the fusiform Bi at different pH levels (3.0 and 7.0) were elucidated. The appropriate degradation pathways were identified via liquid chromatography–mass spectrometry at pH 3.0 and 7.0.
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MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Guang-Ming Bao,Shun-Qiang Cui,Yi-Fan Xia,Zhen-Chong Dou,Xia Wei,Zhi-Qiang Cai,Peiyao Chen,Yi Zhang,Yu-Xin Chen,Hou-Qun Yuan
Amphotericin B (AmB) is an antifungal drug used in dairy farming. It is significant to monitor AmB in milk and environmental water as AmB is severely toxic. Herein, dual emissive Cl, N-codoped carbon dots (Cl, N-CDs) were facilely synthesized and explored as fluorescent probes for specific recognition of AmB among sixty-eight common substances. The Cl, N-CDs possess long emission wavelengths (650 and 482 nm), large stokes shift (240 nm), and high quantum yield (22.06 %). The fluorescence of Cl, N-CDs can be specifically quenched by AmB with a linear concentration range of 0.1–6 μM, a detection limit of 6.67 nM, and a response time within 1 min. Moreover, the Cl, N-CDs can be applied for the determination of AmB in milk and wastewater with good recoveries (92.00–110.00 %). This work provides a facile method for the preparation of Cl, N-codoped CDs with excellent fluorescence properties, and develops a new approach for fluorescence quantification of AmB in real samples.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Hang Yuan,Samaila Boyi Ajeje,Yunzhe Wen,Chonlong Chio,Yun Hu,Shaohua Dou,Wensheng Qin,Ezhen Zhang,Qun Wu,Fubao Sun
Endo-1,4-β-glucanase plays a crucial role in converting cellulose from lignocellulosic biomass into fermentable sugars for biofuel production. However, its commercial utility is hindered by poor catalytic performance under extreme conditions. This study enhanced the catalytic activity of the endo-1,4-β-glucanase ( Tn CelB) from Thermotoga neapolitana through error-prone PCR directed evolution. After screening >4000 colonies, three mutants with enhanced activity were obtained. Mutants Tn CelB Y88F , Tn CelB A233T , and Tn CelB W219R displayed 52.14 U/mg, 44.90 U/mg, and 34.70 U/mg of specific activity on CMC, respectively, which is 1.9, 1.7, and 1.3 times higher than that of the wild-type (26.74 U/mg), correspondingly. Likewise, their enzyme activity on barley β-D-glucan increased by 3.5, 2.2, and 1.8 times, respectively. Notably, Tn CelB Y88F maintained over 90 % activity after 60 mins at high temperatures (80–100 °C), indicating an exceptional thermostability. Protein docking revealed that Tn CelB Y88F had higher binding affinity, aligned with kinetic studies. Tn CelB was capble of released more non-oxidized sugars from the hydrolysis of regenerated amorphous cellulose (RAC) by synergy with auxiliary action family 10 ( AA 10), which is potential in development of efficient lignocellulosic saccharification. This study can provide useful insights for the future engineering of other endoglucanases in the glycoside hydrolases family 12.
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PHYTOTHERAPY RESEARCH
·
2025
·
IF 6.3
Daozheng Fang,Qixiang Shang,Zhihao Liu,Xinyue Li,Quanrun He,Yining Liu,Yong Zhu,Haimeng Li,Tong Wu,Yan-Fang Xian,Jianping Chen,Jihang Chen
Schisandra berry , an edible fruit of the Schisandra genus, produces two main lignans known as Schisandrin A (SchA) and Schisandrin B (SchB). These compounds have garnered significant attention for their beneficial effects in alleviating diabetes and its complications, such as diabetic nephropathy and diabetic neuropathy. However, their protective effects and mechanisms of action against diabetic cardiomyopathy remained largely unknown. In this study, the diabetic cardiomyopathy in vivo model was established by intraperitoneal injection of streptozotocin (STZ) in mice, followed by 2 months of continuous oral administration of SchA and SchB. A positive control group receiving dapagliflozin (DAP) treatment was also included. We conducted a comprehensive evaluation of the protective effects of SchA and SchB against diabetic cardiomyopathy in Type 1 diabetes mellitus (T1DM) mice through a series of experiments, including echocardiography, immunofluorescence staining, immunohistochemistry, western blotting, transcriptomics, and molecular docking simulations, etc. Both SchA and SchB treatment significantly reduced fasting blood glucose level and inhibited dysfunction of pancreatic β-cells. Echocardiography revealed that both SchA and SchB substantially improved cardiac function, including changes in left ventricular muscle thickening, ejection fraction, and fractional shortening. This was accompanied by a reduction in ventricular hypertrophy and myocardial fibrosis following SchA or SchB treatment. Additionally, SchA and SchB treatment exhibited anti-inflammatory and antioxidant effects in mouse heart tissues. Transcriptomics analysis suggested that SchA and SchB may exert their protective effects against diabetic cardiomyopathy by inhibiting the complement cascade, as evidenced by decreased expression levels of genes such as C3, C3a, and C5a. Docking simulations further supported complement factor B as a potential target of SchA and SchB. Our study demonstrated that SchA and SchB exerted protective effects within the framework of T1DM on pancreatic tissues by suppressing apoptosis and preserving the ability of insulin secretion of β-cells. In addition, both SchA and SchB could protect against diabetic cardiomyopathy by inhibiting the complement pathway. These findings highlight the potential therapeutic applications of SchA and SchB in managing diabetic cardiomyopathy in the future.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Qianying Ma,Xiaolong Wang,Rudi Appels,Di Zhang,Xinyu Zhang,Liang Zou,Xinzhong Hu
The starch digestibility of flour is influenced by both physicochemical treatment and flour particle size, but the interactive effect of these two factors is still unclear. In this study, the effect of pullulanase debranching, combined with heat-moisture treatment (P-HMT), on starch digestibility of multi-grain flours (including oat, buckwheat and wheat) differing in particle size was investigated. The results showed that the larger-size flour always resulted in a higher resistant starch (RS) content either in natural or treated multi-grain flour (NMF or PHF). P-HMT doubled the RS content in NMFs and the large-size PHF yielded the highest RS content (78.43 %). In NMFs, the cell wall integrity and flour particle size were positively related to starch anti-digestibility. P-HMT caused the destruction of cell walls and starch granules, as well as the formation of rigid flour aggregates with B + V starch crystallite. The largest flour aggregates with the most ordered B + V starch were found in large-size PHF, which contributed to its highest RS yield, while the medium- and small-size PHFs with smaller aggregates were sensitive to P-HMT, resulting in the lower ordered starch but stronger interactions between starch and free lipid or monomeric proteins, eventually leading to their lower RS but higher SDS yield.
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JOURNAL OF POLYMER SCIENCE
·
2025
·
IF 3.6
Chaogang Fan,Qingyun Ge,Shujuan Lu,Xianshe Feng,Yingfeng Tu,Li Jia,Shaohui Lin,Qinmin Pan,Flora T. T. Ng
A Salen-Co(III)-Cl catalyzed copolymerization strategy is developed for the controlled synthesis of polycarbonate- b -polyester block copolymers through a one-pot process involving CO 2 , 4-vinyl-1-cyclohexene-1,2-epoxy (VCHO), and ε-caprolactone (ε-CL). This procedure is extended to the copolymerization of CO 2 , VCHO, and lactide. The catalytic system is designed and optimized with temperature and CO 2 acting as triggers to switch between CO 2 /epoxide copolymerization and ε-CL homopolymerization. In addition, introducing water as the chain transfer agent reduced the polydispersity index (PDI) of the block copolymers. The copolymer composition can be controlled by adjusting the concentration ratio of epoxides and ε-CL, yielding copolymers with carbonate molar ratios ranging from 14% to 67%. The block copolymers exhibit enhanced thermal stability, and the glass transition temperature ( T g ) can be controlled by adjusting the block composition. Graphical Polycarbonate- b -polyester was prepared via the Salen-Cobalt complex catalyzed copolymerization of CO 2 , epoxide, and ε-caprolactone in one pot. Copolymerization of CO 2 and epoxide and homopolymerization of ε-caprolactone were switched by the control of CO 2 and temperature. By introducing H 2 O as a chain transfer agent, polyester- b -polycarbonate- b -polyester with lower PDI could be obtained.
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CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Ling Wu,Shuang Qi,Tingwei Zhang,Yongcan Jin,Huining Xiao
In this work, new N, O-codoped chitosan-derived carbon adsorbents (CKC-x, x refer to the calcination temperature) were synthesized over a simple process of chitosan-KOH aerogel production and simultaneous carbonization/activation of the aerogel. CKC-700 was characterized by sheet-like morphology (even containing a portion of carbon nano-sheet of 3 nm thickness), high porosity and specific surface area (1702.1 m 2 /g), and pyridinic/pyrrolic/graphitic N groups. The simultaneous carbonization/activation of chitosan-KOH aerogel prepared by top-down coagulation of chitosan aqueous solution by KOH aqueous solution rendered these beneficial characteristics. CKC-700 exhibited a superior adsorption capacity for Rhodamine B (RhB) to other chitosan-derived carbon adsorbents, and the maximum adsorption capacity for RhB of 594 mg/g was achieved at 55 °C. CKC-700 also possessed reasonable reusability for the removal of RhB, and the removal efficiency was still above 95 % in the fifth cycle. The effects of adsorption temperature and time, adsorbent dose, organic dye concentration, and solution pH on the adsorption capacity of CKC-700 were studied. Moreover, the adsorption isotherm , kinetics, thermodynamics, and the adsorption mechanism of RhB on CKC-700 were discussed. In addition, CKC-700 also showed favorable adsorption performance for methylene blue (441 mg/g), methyl orange (457 mg/g), and congo red (500 mg/g) at around 25 °C.
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TALANTA
·
2017
·
IF 4.162
Lu Ding,Chunlan Xiang,Gang Zhou
Poly(acrylic acid) (PAA) brushes coated onto silica nanoparticles have been widely utilized in bioassays due to their abilities of providing favorable microenvironments and ensuring good biological activities for biomolecules. However, traditional PAA brushes are synthesized by reversible addition–fragmentation chain transfer polymerization. Hence, it is generally difficult to control and characterize the molecular weight of the PAA brushes, which may depress the reproducibility and bring more uncertain results. Herein, atom transfer radical polymerization method is employed to synthesize β -cyclodextrin-cored PAA with uniform and controllable molecular weight. After loading on the surfaces of adamantane-functionalized silica nanoparticles via host-guest interactions, glucose oxidase and probe single strand DNA (ssDNA) are further immobilized on the as-prepared nanoparticles. Meanwhile, capture ssDNA is functionalized on amino modified magnetic beads. In the presence of ssDNA sequence of Hepatitis B Virus (HBV) containing completely matched sequence of both probe and capture ssDNA, a bioconjugate is formed and can be separated by an external magnet. The isolated glucose oxidase can further catalyze glucose into gluconic acid and H 2 O 2 , and then reduce HAuCl 4 on Au seeds. By monitoring the absorption intensity change of the Au NPs at 530 nm, the proposed biosensor with novel signal amplification probes can be used to detect DNA sequence of HBV with high sensitivity and selectivity in both buffer and serum samples. This developed strategy has presented a new way to construct silica nanoparticles coated by PAA brushes for the fields of clinical diagnosis and other life sciences.
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JOURNAL OF NANOPARTICLE RESEARCH
·
2024
·Vol. 26
·期 11
·1-9
·
IF 2.1
Jing Fengyang,Zhang Shuping,Wu Yaoyao,Lin Jiuyang,Zhou Chenliang,Yuan Wenjing
The capture of formaldehyde (HCHO) is a crucial step in the HCHO purification system that requires an adjustable surface structure of adsorbent to enhance the HCHO adsorption ability. Carbon material, known to contain high surface area and structural tunability, provides an extremely valuable candidate to eliminate indoor HCHO pollutant. Herein, a novel electron acceptor–donor structure is constructed to the surface of nanoporous carbon based on the B, N doping theory. The mechanism of HCHO adsorption and activation on the surface of B, N co-doped nanoporous carbon (BNC) is systematically investigated by experimental tests that the B–N Lewis pair sites contribute a larger adsorption capacity than that of nitrogen-doping and non-doping samples. The present study gives an in-depth understanding about the contribution of the B–N Lewis pair for HCHO adsorption, and also corresponding positive impacts on the transformation into less toxic intermediate species of adsorbed HCHO at room temperature.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2017
·
IF 3.359
Yang Liu,Hongguang Guo,Yongli Zhang,Xin Cheng,Peng Zhou,Gucheng Zhang,Jingquan Wang,Peng Tang,Tingling Ke,Wei Li
This study represents the first investigation on the application of persulfate (PS)/vis-light for the degradation of Rhodamine B (RhB) using bismuth oxyiodide magnetic composites (BiOI/Fe 3 O 4 , BOMCs). The 3D flower sphere-like BOMCs were successfully fabricated via a hydrothermal method, proving to be an excellent photocatalyst under visible light when evaluated by various characterization methods. The results demonstrated that BOMCs had a high photodegradation efficiency at pH 3.0–9.0 and the BiOI/Fe 3 O 4 (5:1) composite displayed the optimal catalytic performance. Inorganic ions such as Cl − showed promotion at a lower concentration, while significant inhibition was observed for higher concentrations of Cl − and HCO − 3 in the Vis/BOMCs/PS process due to the quenching effect. Moreover, 44.9% mineralization efficiency for total organic carbon and the excellent stability of BOMCs were demonstrated with limited iron leaching. Based on the scavenger experiments, the photocatalytic mechanism in the coupled system determined· SO − 4 and OH as the main reactive species. Eventually, the major intermediates are detected by GC/MS, and a possible photocatalytic degradation pathway of RhB is proposed in the Vis/BOMCs/PS process.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Junwen Cai,Xin Jiang,Linfeng Zhang,Benoit Couturaud,Wen-Zhuo Tang,Yao-Yan Zhang,Rui-Bo Jin,Yoann de Rancourt de Mimérand,Xiaoyun Jin,Jia Guo
A multifunctional, multiphase-supported photocatalyst was fabricated via the combination of LCD three-dimensional (3D) printing, cold plasma discharge (CPD) technology, and surface chemistry to be used for the degradation of organic pollutants in water and for the generation of hydrogen gas. BiOBr was chosen as the main catalytic phase and was used in association with a phosphor, SrAl2O4:Eu2+,Dy3+ (SAED), and a metal–organic framework, Ni-BDC. Their immobilization was realized thanks to polydopamine (PDA), which is used as a coupling agent. While BiOBr was the most active photocatalytic phase, the phosphor acted as a light-storing component for photodegradation in the dark and overall, as a boost for photoactivity. PDA also boosted the photoactivity, in parallel with its crucial role in the immobilization of the SAED/Ni-MOF/BiOBr catalyst on fractal polymer support. An in situ complexation-assisted precipitation (ISCAP) process was used, allowing the formation of the catalytic phases with nano features. The resulting hybrid photocatalysts were tested through rhodamine B (RhB) dye photodegradation upon visible light irradiation or light/dark alternating conditions to simulate more realistic variable light illumination. We found that, although used in a very small amount, the Ni-MOF had a significant impact on the photoactivity, forming a Z-scheme heterojunction with BiOBr. Finally, H2 evolution testing further established the photocatalytic activity and versatility of the supported catalysts.
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CORROSION SCIENCE
·
2024
·
IF 7.4
Keda Xiao,Yi Zeng,Xiang Xiong,Jinrun Hu,Shiyan Chen,Tianyou Li
Si-B-Mo-Y modified SiC/SiC composites were prepared by reactive melt infiltration (RMI) process to study their high-temperature water-oxygen corrosion resistance, and to compare them with SiC/SiC composites prepared by RMI using Si. The results show that the corrosion rates of the modified composites are only 1/9, 1/10 and 1/3 of those of the comparison samples at 1200°C, 1300°C and 1400°C, respectively, which is attributed to the higher densification of the modified composites. More importantly, the modified composites were able to form borosilicates, which effectively healed the oxide film defects; meanwhile, yttrium silicate inhibited the reaction between borosilicates and water vapor.
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