JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2017
·Vol. 28
·期 23
·18200-18206
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IF 2.019
Chen Jianwen,Yu Xinmei,Fan Yun,Duan Zhikui,Jiang Yewen,Yang Faquan
High energy density flexible composite films have been used for the modern compact electronic devices and electric power systems. A novel nanocomposite film is developed by embedding polydopamine encapsulated Ba 0.6 Sr 0.4 TiO 3 nanoparticles (BST NPs) in the polyvinylidene fluoride polymer matrix. The surface functionalization of BST NPs with polydopamine facilitates favorable interaction between the particle and polymer phase, enhancing nanoparticle dispersion. The elaborate functionalization of BST NPs with polydopamine has guaranteed both the increase of dielectric constant and the maintenance of breakdown strength, resulting in significantly enhanced energy storage capability. A finite element simulation of electric field and electric current density distribution suggested the functionalized BST NPs significantly enhanced the breakdown strength and energy density of the composite films. The nanocomposite with 2.5 vol% functionalized BST NPs displays a high energy density of 6.3 J cm −3 at the low field of 3500 kV m −1 , which is larger than that of the biaxially oriented polypropylenes (BOPP) (1.2 J cm −3 at the field of 6400 kV m −1 ). Therefore, the proposed flexible composites films would also find their potential application prospects in electrical devices such as mobile electronic devices, hybrid electric vehicles and military.
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Nano Research
·
2017
·Vol. 10
·期 11
·3629-3637
·
IF 7.354
Li Bo,Chen Shuangming,Tian Jie,Gong Ming,Xu Hangxun,Song Li
Highly efficient and durable water oxidation electrocatalysts are critically important in a wide range of clean energy technologies, including water electrolyzers and rechargeable metal-air batteries. Here, we report a novel sonochemical approach to synthesize amorphous nickel-iron oxides/carbon nanohybrids with tunable compositions for the oxygen evolution reaction (OER). The sonochemically synthesized amorphous electrocatalysts with optimal composition exhibit a low overpotential of 290 mV at 10 mA·cm −2 and a Tafel slope of 31 mV·decade −1 in a 0.1 M KOH electrolyte, outperforming the benchmark RuO 2 catalyst. Meanwhile, these nanohybrids are also highly stable and remain amorphous even after prolonged cycling. In addition to amorphism, sonochemistry endows as-prepared nickel-iron oxides/carbon nanohybrids with a simultaneously formed carbon scaffold and internal Ni(0), which can enhance the stability and activity for the OER. This work demonstrates that sonochemistry is a unique method for synthesizing amorphous metal oxides toward an efficient and durable OER.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2017
·Vol. 28
·期 18
·13556-13564
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IF 2.019
Cheng Chaoliang,Li Junjie,Shi Tielin,Yu Xing,Fan Jinhu,Liao Guanglan,Li Xiaoping,Cheng Siyi,Zhong Yan,Tang Zirong
Due to low melting temperature, low price and high conductivity, copper nanoparticles have great potential to substitute conductive polymers, silver and gold nanoparticles and others in conductive inks. Here we developed a new, simple and green method to synthesize copper nanoparticles, which have the average size of around 140 nm and show remarkable ability to prevent oxidation. Using the copper nanoparticles for conductive ink, the electrical performance of copper film by depositing copper ink on polyimide was also investigated with the sintering temperature from 150 to 400 °C. The electrical resistivity is around 17.0 μΩ cm under sintering temperature of 250 °C, and can reach as low as 5.7 μΩ cm under the temperature of 400 °C. The proposed approach to synthesize copper nanoparticles for high performance conductive ink presents potential applications in flexible electronics.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2017
·Vol. 24
·期 19
·16220-16227
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IF 2.741
Xu Xiangyang,Gao Xinyi,Jin Jie,Vidonish Julia,Zhu Liang
A novel laboratory-scale bioelectrode and anaerobic sludge coupled system was established for the enhancement of p -chloronitrobenzenes ( p -ClNB) reductive transformation with addition of magnetite nanoparticles. In this coupled system, the bioelectrodes were supplied with a voltage of 0.8 V and the amount of magnetite nanoparticles was set at 7.4 mL/400 mL. Results showed that high p -ClNB transformation rate of 0.284 h −1 and high p -chloroaniline ( p -ClAn) dechlorination rate of 0.082 h −1 were achieved in the coupled system at p -ClNB initial concentration of 30 mg L −1 , and p -ClAn is one of the reductive products of p -ClNB. The cyclic voltammetry curve showed that when the potential was −1000 mV, the magnetite-biocathode current was about 10.7 times of the abiotic cathode. Also, a shift in the reductive peak potential and a dramatic increase in reductive peak current were observed. These findings suggest that magnetite nanoparticles could enhance the electrocatalytic activity and may act as electron conduits between microorganisms or between electrodes and microorganisms to promote the extracellular electron transfer.
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Scientific Reports
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2017
·Vol. 7
·期 1
·1-9
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IF 4.259
Li Shan-Shan,Guan Qi-Yuan,Meng Gang,Chang Xiao-Feng,Wei Ji-Wu,Wang Peng,Kang Bin,Xu Jing-Juan,Chen Hong-Yuan
Better understanding the drug action within cells may extend our knowledge on drug action mechanisms and promote new drugs discovery. Herein, we studied the processes of drug induced chemical changes on proteins and nucleic acids in human breast adenocarcinoma (MCF-7) cells via time-resolved plasmonic-enhanced Raman spectroscopy (PERS) in combination with principal component analysis (PCA). Using three popular chemotherapy drugs (fluorouracil, cisplatin and camptothecin) as models, chemical changes during drug action process were clearly discriminated. Reaction kinetics related to protein denaturation, conformational modification, DNA damage and their associated biomolecular events were calculated. Through rate constants and reaction delay times, the different action modes of these drugs could be distinguished. These results may provide vital insights into understanding the chemical reactions associated with drug-cell interactions.
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JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2024
·
IF 2.3
Li Zhi,Hu Min,Shen Kai,Zhou Fang,Chen Zhenkui,Cheng Xudong,Liu Qiong,Wu Xiaoxu
To enhance the thermal safety and preserve the excellent thermal insulation of hydrophobic silica aerogels (SA), sodium dodecyl sulfate (SDS) intercalated layered double hydroxides (LDH) was incorporated into SA by in situ doping to form SDS-LDH/SA composites. The intercalation modification by SDS extends the layer spacing of LDH and improves the dispersibility of LDH in SA, in favor of the combination between LDH and SA. The physical combination between the SA and SDS-LDH is demonstrated by FTIR analyses. As the content of SDS-LDH rises, the SDS-LDH/SA continues to exhibit a low density (0.11–0.20 g/cm 3 ), low thermal conductivity (<26.8 mW/m/K), and large specific surface area (709.4–839.2 m 2 /g), ensuring excellent thermal insulation performance. It further finds that the SDS-LDH effectively absorbs heat and inhibits the thermal decomposition of SA. Therein, the onset temperature of thermal decomposition of the SA with 20% SDS-LDH is 114.0 °C higher than that of pure SA. Additionally, it also finds that the gross calorific values of the SDS-LDH/SA decrease with the SDS-LDH content, and all these gross calorific values are lower than that of the pure SA. Hence, SDS intercalated LDH presents significant effects on enhancing the thermal safety of hydrophobic SA without impairing the thermal insulation too much. Graphical Abstract
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JOURNAL OF NANOBIOTECHNOLOGY
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2024
·
IF 10.6
Jinfeng Shi,Jiahui Zhou,Bo Liu,Kezhou Lin,Xingliang Xie,Xue Han,Yanmei Sheng,Yihan Liu,Congjian He,Yujin Zhou,Nan Zhu,Qian Yang,Ruifeng Luo,Yi Li
Background The oral administration of drugs for treating ulcerative colitis (UC) is hindered by several factors, including inadequate gastrointestinal stability, insufficient accumulation in colonic lesions, and uncontrolled drug release. Methods A multiple sensitive nano-delivery system comprising β-cyclodextrin (CD) and 4-(hydroxymethyl)phenylboronic acid (PAPE) with enzyme/reactive oxygen species (ROS) sensitivity was developed to load celastrol (Cel) as a comprehensive treatment for UC. Results Owing to the positive charge in the site of inflamed colonic mucosa, the negatively charged nanomedicine (Cel/NPs) could efficiently accumulate. Expectedly, Cel/NPs showed excellent localization ability to colon in vitro and in vivo tests. The elevated concentration of ROS and intestinal enzymes in the colon microenvironment quickly break the CD, resulting in Cel release partially to rebalance microbiota and recover the intestinal barrier. The accompanying cellular internalization of residual Cel/NPs, along with the high concentration of cellular ROS to trigger Cel burst release, could decrease the expression of inflammatory cytokines, inhibit colonic cell apoptosis, promote the macrophage polarization, scavenge ROS, and regulate the TLR4/NF-κB signaling pathway, which certified that Cel/NPs possessed a notably anti-UC therapy outcome. Conclusions We provide a promising strategy for addressing UC symptoms via an enzyme/ROS-sensitive oral platform capable of releasing drugs on demand. Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1186/s12951-024-02725-9.
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CHEMICAL PAPERS
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2024
·
IF 2.1
Wei Zijie,Jiang Cuifeng,Chen Xinyan,Li Hui,Song Juan
In this study, Os/Ag nanoparticles (Os/Ag NPs) with smaller K m and almost five times V max compared to Os NPs were prepared. This not only reduced the cost of nanozyme, but also improved the catalytic ability. Addition of L-Cysteine or glutathione (GSH) resulted in inhibitory effect on the peroxidase-like activity of Os/Ag nanozyme. Therefore, the L-Cysteine and GSH could be detected by absorption spectra method with limit of detection (LOD) of 0.22 μM and 0.2 μM, respectively. Moreover, a colorimetric sensing system for L-Cysteine and GSH based on portable paper strip and smartphone was fabricated with LOD of 1.72 μM and 1.4 μM, respectively. Furthermore, this method can be used in fetal bovine serum with recovery rates ranging from 89.42% to 109.0%. The sensing system exhibited good selectivity. This proposed colorimetric sensing assay holds great potential application in the detection of biothiols when no sophisticated equipment are available. Graphical abstract
Scheme illustration for the colorimetric detection of L-Cysteine and GSH by use of smartphone
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Scientific Reports
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2024
·Vol. 14
·期 1
·1-11
·
IF 3.8
Yin Cong,Peng Yinyin,Li Hongjiang,Yang Guang,Yuan Guoyuan
This study aimed to synthesize a novel nanofiber adsorbent based on metal–organic frameworks (MOFs), ZIF-94-PAN, by incorporating ZIF-94 into polyacrylonitrile (PAN) through electrospinning. The investigation of the adsorption characteristics of ZIF-94-PAN for cobalt ions was undertaken, yielding findings that suggest an optimum ZIF-94 loading content within the ZIF-94-PAN composite of 8%. The adsorption experiments revealed that, under pH 8.3 and 298 K, ZIF-94-PAN-8% attained cobalt ion equilibrium adsorption (139.08 mg/g). Additionally, the adsorption kinetics of cobalt ions exhibited conformity with the pseudo-second-order model, whereas adherence to the Freundlich isotherm model indicated a non-homogeneous, endothermic process. XPS analysis unveiled that the adsorption mechanism was characterized by the coordination of nitrogen and oxygen atoms within ZIF-94-PAN with cobalt ions. This study effectively addressed the challenges of separating and recovering MOFs adsorbents by fabricating them as nanofibers. The remarkable adsorption performance and stability of the ZIF-94-PAN nanofibers highlight their potential for removing cobalt-contaminated wastewater.
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JOURNAL OF NANOBIOTECHNOLOGY
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2024
·Vol. 22
·期 1
·1-18
·
IF 10.6
Jin Jiale,Xia Xiaowei,Ruan Chengxin,Luo Zhiyuan,Yang Yiqi,Wang Dongyu,Qin Yifang,Li Dongdong,Zhang Yong,Hu Yihe,Lei Pengfei
Macrophage metabolism dysregulation, which is exacerbated by persistent stimulation in infectious and inflammatory diseases, such as diabetic infectious bone defects (DIBD), eventually leads to the failure of bone repair. Here, we have developed an injectable, macrophage-modulated GAPDH-Silence drug delivery system. This microsphere comprises chondroitin sulfate methacrylate (CM) and methacrylated gelatin (GM), while the dimethyl fumarate (DMF)-loaded liposome (D-lip) is encapsulated within the microsphere (CM@GM), named D-lip/CM@GM. Triggered by the over-expressed collagenase in DIBD, the microspheres degrade and release the encapsulated D-lip. D-lip could modulate metabolism by inhibiting GAPDH, which suppresses the over-activation of glycolysis, thus preventing the inflammatory response of macrophages in vitro. While beneficial for macrophages, D-lip/CM@GM is harmful to bacteria. GAPDH, while crucial for glycolysis of staphylococcal species ( S. aureus ), can be effectively countered by D-lip/CM@GM. We are utilizing existing drugs in innovative ways to target central metabolism for effective eradication of bacteria. In the DIBD model, our results confirmed that the D-lip/CM@GM enhanced bacteria clearance and reprogrammed dysregulated metabolism, thereby significantly improving bone regeneration. In conclusion, this GAPDH-Silence microsphere system may provide a viable strategy to promote diabetic infection bone regeneration.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-17
·
IF 15.7
Zheng Haiyan,Zhang Lu,Bai Xinning,Zhu Jinchao,Liu Shanshan,Ke Yao,Lin Qingyuan,Yuan Yuan,Ji Tianhai
Glioblastoma (GBM) is a highly invasive malignancy with a poor prognosis, primarily attributable to its diffuse infiltration into adjacent brain tissue, thereby complicating effective surgical resection. Current imaging modalities often struggle to accurately identify tumor boundaries. Here, we identify general control non-repressed protein 5 (GCN5) as a promising molecular target for GBM imaging, as it is expressed in GBM lesions within brain tissue, and its expression levels are significantly correlated with GBM grading. We develop a dual-modal probe with a particle size of 20 nm, capable of efficiently traversing the blood-brain barrier (BBB) to target GCN5 through adsorptive-mediated transcytosis (AMT). The probe employs dendrimers (Den) as carriers, which are loaded with a small molecule inhibitor specifically designed to target GCN5. This probe enhances the preoperative delineation of GBM boundaries using magnetic resonance imaging (MRI) and facilitates intraoperative fluorescence image-guided surgical procedures. Our work introduces a promising tool for boundary delineation, offering new opportunities for the precise resection of GBM.
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npj Flexible Electronics
·
2024
·Vol. 8
·期 1
·1-10
·
IF 12.3
Tang Lixue,Wang Huayi,Ren Jifeng,Jiang Xingyu
Stretchable electronic circuits can seamlessly conform to irregular and dynamic surfaces with high integration. However, current stretchable configurations typically have limited stretchability due to the lack of robust connections between soft interconnects and rigid electronics. Here, we printed highly stretchable metal–polymer conductors on thermoplastic elastomers as interconnects. We developed electronic vests with porous surfaces for rigid electronics and introduced polyester hot-melt adhesives to strengthen connections between soft interconnects and rigid electronics. After thermal bonding, the adhesive penetrates the porous surface of electronic vests, creating a mechanical interlock and providing an adhesion force of 8.34 N/cm for the connection (3× higher than conductive adhesives). Thus, rigid electronics of different sizes and different pin counts can form strong connections to soft interconnects, achieving a maximum strain tolerance of ~700% (10× higher than conductive adhesives). We achieved highly integrated ultra-stretchable displays that can withstand stretching up to 220% without dead pixels.
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