CERAMICS INTERNATIONAL
·
2022
·Vol. 48
·期 15
·22179-22186
·
IF 5.532
Wenqi Yang,Fuxing Ye,Hang Qi
Due to the restriction of CMAS corrosion, the YSZ TBCs are facing great challenges, which accelerates the development of the novel potential thermal barrier materials. This work has investigated the CMAS corrosion resistance of the novel thermal barrier material GdTaO 4 and YbTaO 4 to assess their potential in replacing the traditional YSZ . The results indicate that GdTaO 4 and YbTaO 4 possess excellent phase stability, and there is no phase transition after 150 h sintering at 1350 °C. The crystallization phenomenon has occurred in the residual CMAS when the reaction time is 0.5 h, and the main crystallization product is CaMgSi 2 O 6 . In comparison, when the reaction time increase to 10 h, the crystallization phenomenon has disappeared completely. The maximum reaction layer thickness of GdTaO 4 and YbTaO 4 are ∼10 μm and ∼6 μm after 10 h CMAS corrosion, respectively. The XRD patterns indicate that the main product after 10 h reaction is Ca 2 Ta 2 O 7 . Compared with the CaMgSi 2 O 6 , the Ca 2 Ta 2 O 7 possesses lower formation enthalpy and cohesion energy. With the reaction time rising, the formation of Ca 2 Ta 2 O 7 consumes lots of Ca elements and restrain the formation of CaMgSi 2 O 6 . Besides, the difference of GdTaO 4 and YbTaO 4 in CAMS corrosion resistance is also attributed to cohesion energy. These results indicate that GdTaO 4 and YbTaO 4 exhibit enormous potential to manufacture the novel TBCs in CMAS corrosion resistance compared with the YSZ.
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2019
·
IF 4.833
Wen-Jing Zhu,Ben-Wen Cui,Hui Min Wang,Ji-Xing Nan,Hu-Ri Piao,Li-Hua Lian,Cheng Hua Jin
Six series of 4-(benzo[ c ][1,2,5]thiadiazol-5-yl)-3(5)-(6-methylpyridin-2-yl)- pyrazoles 18a – d , 19a – d , 22a – d and 3(5)-(6-methylpyridin-2-yl)-4-(thieno[3,2,- c ]- pyridin-2-yl)pyrazoles 20a – d , 21a – d , 23c , 23d have been synthesized and evaluated for their activin receptor-like kinase 5 (ALK5) and p38α mitogen activated protein (MAP) kinase inhibitory activities in enzymatic assays. Among these compounds, the most active compound, 22c , inhibited ALK5 phosphorylation with an IC 50 value of 0.030 μM in the enzymatic assay. Compound 22c showed four-fold more potent activity against ALK5 kinase than the clinical candidate, compound LY-2157299 . The selectivity index of 22c against p38α MAP kinase is 235, which is much higher than that of LY-2157299 (4) and equally selective to that of EW-7197 (218). Compound 22c effectively suppressed protein and mRNA expression of collagen I and α-SMA in TGF-β-induced LX-2 human hepatic stellate cell (HSC), this result shows that compound 22c has the ability to inhibit the activation of HSC. Compound 22c is expected to be a preclinical candidate for the treatment of hepatic fibrosis .
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Hengyi Lu,Huanxiao Li,Chuyang Liu,Jiayi Shao,Fangqi Guo,Xiang Tian,Xiaopeng Li,Pan Ying,Yujing Zhang,Guangbin Ji
To tackle the complex electromagnetic pollution from advances in radar and network technologies, a simple, low-cost, and efficient absorbing agent has been developed. By optimizing the high-temperature sintering of the melamine/reduced iron powder composite system, we successfully created a Fe-C-N multiphase composite material with multi-level structure and dielectric-magnetic loss properties. The gas produced by the decomposition of melamine at high temperatures fosters the formation of a pore structure. Additionally, controlling the heating temperature and holding time effectively manages the phase transition path, allowing for synergistic evolution of the microstructure and regulation of the microwave-absorbing properties. The analysis of SEM images and XRD results identifies the synergistic enhancement mechanism between the multi-level structure and multi-phase. This endows a reflection loss of -75.91 dB at 5.16 GHz for samples held at 700°C for 3 hours (thickness 4.4 mm), with a maximum bandwidth of 4.92 GHz (1.6 mm). It avoids the traditional multi-step process of carbon/nitrogen doping, effectively regulating the phase transition path and microstructure evolution. This provides a new approach to develop lightweight, broadband microwave absorbing materials.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Jian Gu,Wentian Cui,Hongzhi Cheng,Didi Cao,Jian Yang,Junyang Jin,Lin Zhao,Hongkang Wei,Meiling Yu,Zhipeng Xie,Chang-an Wang
In this study, transition metal halides and phenolic resin were utilized to synthesize (TiHfVNb)C medium-entropy precursors by multi-metal organic frameworks (MOFs) method. The (TiHfVNb)C submicron particles were obtained by carbothermal reduction at a relatively low temperature (1500 °C) and subsequently consolidated into medium-entropy carbide ceramics via spark plasma sintering at 1950 °C. Effects of molar ratios of transition metal halides and phenolic resin, pyrolysis temperatures and holding time on the properties of MOFs-derived (TiHfVNb)C submicron particles was systematically investigated. Comprehensive characterization was performed on the as-synthesized submicron particles using FTIR, TGA, XRD, SEM, EDS and TEM, revealing that the as-synthesized submicron particles exhibited an elliptical morphology with fine particles size (~150 nm) and uniform particle size and elemental distribution. The MOFs-derived (TiHfVNb)C ceramic by SPS achieved a high density of 99.6% and displayed homogeneous microstructure. Remarkably, the SPS-sintered (TiHfVNb)C ceramics demonstrated competitive mechanical properties, with Vickers hardness and fracture toughness values reaching 21.7 GPa and 4.4 MPa·m¹ / ², respectively.
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ACS Catalysis
·
2026
·
IF 13.6
Jun-Bin He,Lian Wu,Wenli Yuan,Hai-Xue Pan,Binju Wang,Gong-Li Tang
Achieving highly regioselective C–H bond functionalization at the bridgehead carbon of a single molecule is a fascinating, yet formidable challenge. BcmD, a P450 enzyme, catalyzes the regioselective hydroxylation at the sp3-hybridized bridgehead carbon of the bicyclo[4.2.2]piperazinedione ring scaffold during bicyclomycin biosynthesis. Herein, we provide mechanistic details of BcmD to understand its substrate binding and the origin of its regioselectivity. The high-resolution structure of SoBcmD from Streptomyces ossamyceticus in complex with its natural substrate, together with site-directed mutagenesis and computational simulations, reveals that the precise substrate positioning, enabled by specific hydrogen-bonding and hydrophobic interactions with crucial residues, determines the regioselectivity. Intriguingly, we identify SoBcmD as a peroxygenase that could utilize H2O2 as an oxidant to catalyze regioselective hydroxylation. Mechanistic analysis indicates that H2O2 activation in SoBcmD involves a homolytic cleavage process, mediated by a hydrogen-bonding network comprising residues T277, A273, and the substrate. Furthermore, structure-based channel analysis and mutagenesis demonstrate that the I157V mutant exhibits significantly enhanced peroxygenase activity. These findings advance our understanding of regioselectivity control in BcmD and provide valuable guidance for engineering P450 peroxygenases for the C–H bond activation at the chemically challenging bridgehead carbon sites.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2026
·
IF 3.9
Lemeng Wang,JiChao Hu,Jian Ma,Zedong Niu,YuChen Liu,Luanxiang Chao,Hemu Liu,Ruigeng Xie,Yuetong Zhao,Chenlu Mi,Kun Zhao,Dong Fu,Pengfei Qu,Pan Zhang
The industrial application of MEA-based carbon capture processes is significantly constrained by a low desorption rate and high energy consumption. To address these limitations, a NiCo@C catalyst was synthesized by using a hydrothermal-assisted impregnation method. The incorporation of Ni–Co dual doping into the carbon-based framework not only enhanced its stability and catalytic activity but also optimized its pore structure. A series of systematic characterizations were performed to evaluate the physicochemical properties of the material. The results indicate that the NiCo@C catalyst exhibits a substantially larger specific surface area and pore size compared to the Ni@C and Co@C catalysts. Additionally, the bimetallic catalysts introduce both weakly acidic and strongly acidic sites while maintaining a well-defined three-dimensional spherical structure. Compared to the noncatalytic MEA system, the introduction of NiCo@C increases the maximum desorption rate by 158% and the maximum desorption amount by 41.24%. These improvements contribute to a 53.48% reduction in energy consumption along with excellent cycle stability. The catalytic mechanism of NiCo@C was further investigated using 13C NMR, FT-IR, and Raman spectroscopy. The results reveal that bifunctional acid synergy in the solid NiCo@C catalyst promotes proton transfer and facilitates the breaking of C–N bonds, thereby enabling more efficient desorption with a lower energy consumption.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 9.2
Wanyu Li,Muzi Liu,Xiangyu Xin,Yu Xiao,Jinping Li,Guang Liu
MgH 2 is recognized as an exceptionally promising solid-state material for hydrogen storage, but its high thermodynamic stability, slow kinetics, and cycling-induced particle coarsening remain major obstacles to practical application. In this study, a composite oxide catalyst, Nb 2 O 5 @TiO 2 -C, was synthesized via a hydrothermal route by loading nano-Nb 2 O 5 onto a TiO 2 -C support derived from a Ti-based metal- organic framework. Doping with Nb 2 O 5 @TiO 2 -C markedly enhances the hydrogen storage performance of MgH 2 . Carbon within the support effectively suppresses nanoparticle agglomeration, while the catalyst is partially reduced to low-valence species during de/rehydrogenation cycles, both contributing to the enhanced performance. The MgH 2 -7 wt.% Nb 2 O 5 @TiO 2 -C composite starts dehydrogenating at 210.6 °C. At 300 °C, it rapidly releases over 6 wt% hydrogen within 5 min. The dehydrogenated sample also exhibits fast absorption kinetics, absorbing 6 wt% hydrogen within 1 min at 200 °C under 30 bar H 2 . Moreover, the system shows excellent cycling stability, retaining a hydrogen capacity of 6.6 wt% after 20 cycles.
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International Journal of Applied Ceramic Technology
·
2026
·Vol. 23
·期 1
·e70145
·
IF 2.3
Wenlong Zhang,Zhipeng Sun,Guixiu Liao,Yutong Ren,Ling He,Ling Pan,Yuhai Lu,Peng Xiao,Wei Zhou,Junjie Duan,Yang Li
Rare-earth hafnates show promising potential use in the development of a new generation of thermal/environmental barrier coatings (T/EBCs) owing to their high melting point, phase stability, and compatibility with SiC-based composites. In the current work, microstructural evolution and corrosion behavior of Yb 4 Hf 3 O 12 ceramics exposed to wet-oxygen and ambient air atmospheres at 1400°C were systematically investigated. Results revealed that sintering in air led to pronounced grain growth and homogenization, followed by secondary recrystallization at extended durations. Under wet-oxygen conditions, the ceramics underwent two distinct stages: initial Hf 4 + hydration and volatilization (0–20 h), and subsequent formation of Al 5 Yb 3 O 12 corrosion products due to reactions with Al(OH) 3 impurities (20–40 h). These processes induced fluctuations in grain size distribution, including growth, refinement, and re-coarsening, accompanied by microstructural densification and grain boundary corrosion. The findings highlight the pronounced role of water vapor and trace environmental impurities, demonstrating that alumina-based furnace environments can act as a variable influencing the structural integrity and apparent degradation behavior of Yb 4 Hf 3 O 12 , thereby providing valuable guidance for mechanistic studies of high temperature corrosion in future experimental investigations.
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CERAMICS INTERNATIONAL
·
2026
·
IF 5.6
Siyi Xiong,Yuan-Bin Chen,Junyu Chen
Currently, research on A 3+ B 3+ O 3 - type microwave dielectric ceramics is scarce. To address these challenges, a novel perovskite - type LaTmO 3 ceramic with a single phase orthorhombic structure (space group Pnma (62)) was synthesized via the solid state reaction method at 1450–1575 °C. Furthermore, SEM was employed to observe the microstructure of the sample, and Raman spectroscopy was utilized to analyze the impact of lattice vibrations on dielectric loss. Additionally, calculations based on the complex chemical bond theory revealed that the values of the εᵣ , Q×f , and τ f were influenced by bond ionicity, lattice energy, and bond energy, respectively. The LaTmO 3 ceramic sintered at 1525 °C demonstrated optimal microwave dielectric properties: Q×f = 179,601 ± 9579 GHz (at 8.4 GHz), εᵣ = 27.8 ± 0.18, and τ f = +9.8 ± 1.5 ppm/°C. Moreover, HFSS simulations demonstrated the applicability of LaTmO 3 in dielectric resonator antennas, achieving >90 % radiation efficiency, about 5.5 dBi gain, and 130 MHz bandwidth at 4.7 GHz, highlighting its potential for 5G oriented components.
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Nature Communications
·
2026
·
IF 15.7
Ya Zongyang,Li Mei,Fu Donglong,Zheng Yu,Wei Ruhan,Wang Hao,Zhang Kangning,Xu Dong,Zhang Zixuan,Zhang Xue,Yan Shen,Wang Hua,Zhang Shengbo,Gong Jinlong
Photocatalytic C−N coupling offers a promising approach for the sustainable production of amino acids, but the uncontrolled coupling pathway of reaction intermediates limits yield and selectivity. This paper describes a Pd−B diatomic catalyst that can selectively catalyze the photosynthesis of glycine via C−N coupling reaction between waste poly(ethylene terephthalate)-derived ethylene glycol and nitrate, achieving a glycine yield of 2.9 mmol g cat −1 h −1 with a selectivity of 92%. Mechanistic investigations reveal that ethylene glycol is photo-oxidized to glycolaldehyde at the hole-rich B site, while nitrate is photo-reduced to NH 4 + /NH 3 at the electron-rich Pd site. Subsequently, glycolaldehyde undergoes C−N coupling with NH 4 + /NH 3 , and further photo-oxidized to form glycine. The Pd−B diatomic site more effectively stabilizes the glycolaldehyde intermediate, resulting in a more favorable C−N coupling pathway than metal oxide and enhancing glycine selectivity. Thus, we show a catalytic system for selective glycine photosynthesis by precisely regulating the reaction pathways of key intermediates.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.3
Hongwei Zhou,Ying Lin,Yongzhen Ma,Zhao Meng,Haibo Yang
To obtain high-performance electromagnetic wave (EMW) absorption materials with a broad effective absorption bandwidth (EAB), structural design has proven to be an effective strategy. In this investigation, Co/C@carbon nanofibers (Co/C@CNFs) derived from metal-organic frameworks (MOFs) were integrated with graphite oxide (GO) nanosheets, and Co/C@CNFs/GO aerogels were prepared through unidirectional freeze-drying followed by heat treatment. The resulting aerogels exhibit a unique directional channel structure that increases their contact area with air, thereby improving impedance matching. The Co/C@CNFs/GO aerogels demonstrate exceptional EMW capabilities, primarily due to the multiple heterogeneous interfaces and the synergistic electromagnetic loss mechanisms generated by the interactions among GO nanosheets, CNFs, and Co particles. The results reveal that Co/C@CNFs/GO-2 achieves remarkable EMW absorption with a maximum EAB of 10.0 GHz, covering both the X and Ku bands, thanks to its directional channel structure and complete conductive network. Moreover, the aerogels exhibit excellent radar cross-section attenuation and superior thermal insulation. This work provides a reliable strategy for synthesizing multifunctional carbon-based aerogels materials with efficient EMW absorption, offering broad potential for applications in electromagnetic protection, thermal management, and related fields.
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Nature Communications
·
2026
·
IF 15.7
Lai Dingbo,Yu Jia,Ma Zi-Ang,Ye Xiaolin,Wang Chaoxi,Zhang Junqing,Wang Tuo,Zhao Zhi-Jian,Zhang Peng,Gong Jinlong
The electrochemical C–N coupling of biomass-derived 5-hydroxymethylfurfural (HMF) with methylamine offers a promising sustainable route to value-added amines. However, achieving high selectivity remains challenging due to competing side reactions, including C = O hydrogenation and C–C dimerization. This paper describes tailoring the surface structure of Ag catalysts to modulate HMF adsorption and intermediate hydrogenation behavior and thus enhancing C–N coupling selectivity. Ag nanoparticles, predominantly exposing the (111) facet, exhibit higher selectivity compared with Ag nanocubes mainly enclosed by (100) planes. The Ag(111) facet favors the C–N coupling pathway by regulating both adsorption geometry and hydrogenation ability. In-situ Raman spectroscopy and density functional theory (DFT) calculations reveal that an η 1 (C)-aldehyde adsorption configuration, dominant on Ag(111), enhances carbonyl electrophilicity and facilitates C = O polarization, promoting nucleophilic attack by methylamine. In contrast, the η 2 (C,O)–aldehyde configuration, more common on Ag (100), stabilizes the C = O bond, limiting its reactivity. Moreover, Ag(111) shows enhanced imine hydrogenation activity, further improving amine selectivity. This study highlights the significance of facet-dependent adsorption modulation in steering reaction pathways and advancing sustainable electrochemical synthesis.
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