CHEMICAL ENGINEERING JOURNAL
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2022
·
IF 16.744
Yunhan Bai,Xiaoshu Ding,Ying Sun,Yucong Song,Yanji Wang
The reverse water gas shift (RWGS) reaction is one kind of the catalytic conversion of CO 2 to reduce an enormous amount of CO 2 . However, the RWGS reaction has the safety hazards associated with the use of hydrogen and thermodynamic limitation. Therefore, this work proposes a new safe and efficient reaction route (CO 2 -MCH) to get CO from CO 2 and methylcyclohexane (MCH). Thermodynamic calculations showed that the equilibrium CO 2 conversion at 350 °C increased from 17.8 % of the RWGS reaction to 53.5 % of the CO 2 -MCH reaction. In the CO 2 -MCH reaction, the relationship of the catalytic performance with the metal dispersion, the Pt particle size and the acidity of Pt-based catalysts on the different supports was investigated, respectively. The results showed that the Pt/γ-Al 2 O 3 catalyst with high dispersion of Pt particles, small particle size and medium acidity had good activity and selectivity. The relationships among Pt loading and Pt particle size on the Pt/γ-Al 2 O 3 catalyst and the catalytic performance were evaluated. The Pt particle size gradually increased with the metal loading. A positive correlation was observed between Pt particle size and CO 2 conversion; a volcano-type relationship was observed between CO selectivity and Pt particle size. In the CO 2 -MCH reaction at 350 °C, 0.1 MPa, LHSV = 6 h −1 , the CO 2 conversion was 24.7 %, the CO selectivity reached 95.2 %, and the Pt/γ-Al 2 O 3 catalyst within 40 h showed good stability. Moreover, the mechanism of the CO 2 -MCH catalytic reaction over the Pt/γ-Al 2 O 3 catalyst was speculated.
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MICROCHEMICAL JOURNAL
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2022
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IF 5.304
Nana Yang,Xinyong Zhou,Xinru Qi,Jiahao Li,Weiming Fang,Huaiguo Xue,Zhengfei Yang
Measurement of nitrite is needed for the control of nitrite pollution and to decrease the health risks and protect environment. It is attractive to design novel electrocatalysts for the efficient electrochemical quantification of nitrite. Herein, a sequence of Co, N -doped-porous carbon rods (CoN-PCRs) were designed and prepared through the calcination of rod-shaped mixed-metal zeolitic imidazolate framework precursors (ZIF-L) with different Co/Zn ratios. It was observed that the highest surface area and best response were obtained with the CoN-PCRs-0.6. Furthermore, its morphology and structure were characterized by several techniques. Additionally, the electrochemical sensing performances of CoN-PCRs-0.6 to nitrite were studied. Benefiting from the structural merits, the constructed sensor showed a low detection limit of 0.14 μM and achieved two wide dynamic ranges 0.2–4000 μM and 4000–100000 μM. The sensor also possessed good specificity, reproducibility, and stability toward nitrite quantification. Ultimately, the rapid and accurate measurement of nitrite in tap water was successfully realized.
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Frontiers in Bioengineering and Biotechnology
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2022
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IF 6.064
Yuanyao Dou,Yimin Zhang,Caiyu Lin,Rui Han,Yubo Wang,Di Wu,Jie Zheng,Conghua Lu,Liling Tang,Yong He
Multiple component integration to achieve both therapy and diagnosis in a single theranostic nanosystem has aroused great research interest in the medical investigator. This study aimed to construct a novel theranostic nanoplatform ferrite and ceria co-engineered mesoporous silica nanoparticles (Fe/Ce-MSN) antioxidant agent though a facile metal Fe/Ce-codoping approach in the MSN framework. The resulted Fe 3+ -incorporated ceria-based MSN nanoparticles possessing a higher Ce 3+ -to-Ce 4+ ratio than those revealed by ceria-only nanoparticles. The as-prepared Fe/Ce-MSN nanoparticles exhibited an excellent efficiency in scavenging reactive oxygen species (ROS), which is attributed to improving the superoxide dismutase (SOD) mimetics activity by increasing Ce 3+ content and maintaining a higher activity of catalase (CAT) mimetics via including ferrite ion in nanoparticles. The fast Fe/Ce-MSN biodegradation, which is sensitive to the mild acidic microenvironment of inflammation, can accelerate Fe/Ce ion release, and the freed Fe ions enhanced T 2 -weighted magnetic resonance imaging in the inflammation site. PEGylated Fe/Ce-MSN nanoparticles in vitro cell models significantly attenuated ROS-induced inflammation, oxidative stress, and apoptosis in macrophages by scavenging overproduced intracellular ROS. More importantly, Fe/Ce-MSN-PEG NPs exhibited significant anti-inflammatory effects by inhibiting lipopolysaccharide (LPS)-induced expression of tumor necrosis factor-α (TNF-α) and interleukin-1 beta (IL-1β) levels in vitro . Additionally, it can promote the macrophages polarization of pro-inflammatory M1 phenotype towards an anti-inflammatory M2 phenotype. Thus, the novel pH-responsive theranostic nanoplatform shows great promise for inflammation and oxidative stress-associated disease treatment.
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PubMed
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
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2022
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IF 5.876
Lina Zhang,Yutao Jia,Han Hao,Mi Wang,Jing Wang
Mitochondria-targeted therapeutic strategies are widely used in the targeted delivery of anti-tumor drugs to achieve effective and precise treatment. Herein, a pH-responsive and mitochondria-targeted liposome-enveloped methoxylated covalent organic framework (mCOF) delivery system loaded with doxorubicin (DOX) and camptothecin (CPT) is constructed. Different from introducing additional mitochondria-targeting molecules, we incorporate amphiphilic DOX-lipid molecules into a lipid bilayer to achieve mitochondria-targeted and therapeutic agent delivery (DOX) to induce oxidative stress in tumor mitochondria. Furthermore, CPT, which can also induce mitochondrial oxidative stress, is co-loaded with DOX-lipid using mCOF with high porosity to enhance the synergistic therapeutic effects. In addition, cholesteryl hemisuccinate is assembled with amphiphilic DOX-lipid on the surface of the mCOF to achieve pH-sensitive drug release. Consequently, the DOX-CPT dual drug-loaded delivery system with mitochondria-targeted ability can efficiently increase the level of reactive oxygen species in the mitochondria and enhance anti-tumor efficacy compared with other groups. Given its good biocompatibility, the constructed dual drug delivery platform based on liposome-enveloped mCOF synergistically combines mitochondria-targeted DOX-lipid with mitochondria-acted CPT, which provides a feasible strategy for organelle-targeted combination chemotherapy to improve therapeutic effects.
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POLYMER DEGRADATION AND STABILITY
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2022
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IF 5.204
Congling Shi,Mei Wan,Zhengbo Hou,Xiaodong Qian,Honglei Che,Yueping Qin,Jingyun Jing,Jian Li,Fei Ren,Bin Yu,Ningning Hong
Thermoplastic polyurethane (TPU) is the most used polyurethane, but its highly flammable characteristic restricts its extensive use. In this work, Co-MOF@MXene hybrids flame retardants were synthesized and incorporated into TPU . The flame-retardant characteristics of TPU composites were investigated by cone calorimeter test and thermogravimetric analyzer. Compared with TPU, the peak heat release rate and total heat release rate of TPU/Co-MOF@MXene composites were reduced by 28.3% and 14.5%, respectively; and the smoke production rate and total smoke production of the composites with only 2 wt% Co-MOF@MXene hybrids were also reduced by 58.8% and 47.5%, respectively. Furthermore, the char residues of TPU/Co-MOF@MXene composites were about 2 times that of pure TPU. Systematical characterizations were then carried out to investigate the flame retardant mechanism of Co-MOF@MXene hybrids, highlighting the barrier effects of MXene combined with the catalytic effect of Ti and Co. The hybrids flame retardants greatly benefit the further development of TPU nanocomposites.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2022
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IF 10.319
Yunfei Zhang,Yulong Li,Mengmeng Wei,Dengtao Yang,Qiuyu Zhang,Baoliang Zhang
In this study, a new lightweight one-dimensional absorber Co@NC@MoS 2 was designed and prepared. Firstly, polydopamine (PDA) was coated by oxidative self-polymerization with cobalt-nitrilotriacetic acid chelate nanowires (Co-NTAC) as template. Then core-shell structured magnetic hierarchical nanotubes (Co@PDA@MoS 2 ) were prepared by one-step hydrothermal method. After thermal annealing, PDA layer was transformed into nitrogen doped carbon layer (NC) to obtain the efficient microwave absorber Co@NC@MoS 2 . The removal of template and growth of MoS 2 were completed simultaneously, the preparation process was simplified. Because of its good magnetic loss and dielectric loss, Co@NC@MoS 2 shows excellent microwave absorption performance. Under filler content of 15 wt.%, the minimum reflection loss (RL min ) can reach -61.97 dB@9.2 GHz, and the effective absorption bandwidth (EAB) is 5.6 GHz. The electromagnetic parameters of Co@NC@MoS 2 can be further adjusted by changing the load of MoS 2 . Meanwhile, the structure and composition of Co@NC@MoS 2 were systematically analyzed. The influence of the microstructure on the microwave absorbing properties was investigated, and the microwave attenuation mechanism is revealed. As an efficient and lightweight absorber, Co@NC@MoS 2 has potential application value in the construction of new stealth coatings.
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高影响因子
CARBON
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2022
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IF 11.307
Dandan Han,Qian Zhou,Yan Xia,Dongting Huang,Jieqiong Qin,Lixia Wang,Xiaopeng Wang,Xianfu Zheng,Dan Wu
The bottom-up assembly utilizing nanocrystals (NCs) as building blocks is a highly anticipated approach to access novel metamaterials. Limited by the library of binary spherical assembly, colloidal components of building blocks are necessarily extended for targeting the desired assembled-superstructure with emergent properties. Here, a generalized approach is presented that carbon nanotubes (CNTs) capped with long-chain hydrocarbon ligands, as creative colloidal components, can be compatibly co-assembled with various NCs into binary supraspheres based on a confinement microemulsion environment. Such cross-dimensional assemblies possess the structural merits of excellent conductivity, abundant voids and high stability, thus synergistically boosting its electrochemical performance. As a proof of concept , the co-assembled CoFe 2 O 4 /CNTs supraspheres exhibit extraordinary capacity (890 mAh g −1 at 0.5 A g −1 ), rate capability (318 mAh g −1 at 20 A g −1 ), and structural stability (458 mAh g −1 at 5 A g −1 after 1000 cycles) relative to pure CoFe 2 O 4 when evaluated in Li-ion battery. Beyond that, its derived phosphides CoFeP/CNTs assemblies outperform most of the state-of-art electrodes when acting as electrocatalysts for hydrogen evolution reactions (HER). This work provides a new perspective for constructing superstructures of NCs for potential applications in energy storage devices.
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INTERNATIONAL JOURNAL OF ENERGY RESEARCH
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2022
·Vol. 46
·期 13
·18624-18633
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IF 4.672
Honghong Cheng,Bo Li,Tao Meng,Cong Liu,Dong Shu
Summary Practical applications of graphene-based materials are still inhibited by the serious restacking of graphene nanosheets and single electrical double-layer capacitor energy storage mechanism. To address these issues, nitrogen/sulfur-co-doped reduced graphene oxide (N/S-rGO) was ingeniously prepared by supermolecular-driven in-situ co-dope method. In this article, the GO/L-cysteine supermolecular system was assembled first, the hydrogen bond between L-cysteine and GO is confirmed by the Fourier-transform infrared spectroscopy (FTIR). The theoretical calculation result indicating that L-cysteine is uniformly assembled on GO surface by supermolecular interaction force (dispersion force and hydrogen bond). Due to the oriented supermolecular force, the thus-fabricated N/S-rGO affords customized three-dimensional (3D) porous structure, uniform N,S co-doping, effective electrolyte ion-transport pathways, and satisfactory structural stability. Attributing to the inherent plentiful 3D cavity structure and synergistic effect between N, S heteroatoms, N/S-rGO shows outstanding electrochemical performance, the best-performed N/S-rGO2 possess delightful capacitance (416 F g −1 ), after 20 000 cycles the capacitance retention of N/S-rGO is 110% of the initial value, shows excellent cycle reliability. The N,S-rGO all-solid flexible symmetrical supercapacitor can light up luminous diode for 30 seconds when fully charged, indicating that it provides the possibility of practical application.
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ACS Applied Materials & Interfaces
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2022
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IF 10.383
Hanhao Huang,Yulian Shang,Haofei Li,Qi Feng,Yang Liu,Junlin Chen,Hua Dong
Pancreatic islets transplantation is an optimal alternative to exogenous insulin injection for long-term effective type 1 diabetes treatment. However, direct islets transplantation without any protection can induce cell necrosis due to severe host immune rejection. Insufficient O2 supply induced by the lack of capillary network at the early stage of islets transplantation is another critical constraint limiting islets survival and insulin-secretion function. In this paper, we design a novel co-transplantation system composed of islets-laden nanocomposite microgels and O2-generating microspheres. In particular, nanocomposite microgels confer the encapsulated islets with simultaneous physical protection and chemical anti-inflammation/immunosuppression by covalently anchoring rapamycin-loaded cyclodextrin nanoparticles to microgel network. Meanwhile, O2-generating microspheres prepared by blending inorganic peroxides in biodegradable polycaprolactone and polylactic acid can generate in situ O2 gas and thus avoid hypoxia environment around transplanted islets. In vivo therapeutic effect of diabetic mice proves the reversion of the high blood glucose level back to normoglycemia and superior glucose tolerance for at least 90 days post co-transplantation. In brief, the localized drug and oxygen codelivery, as well as physical protection provided by our co-transplantation system, has the potential to overcome to a large extent the inflammatory, hypoxia, and host immune rejection after islets transplantation. This new strategy may have wider application in other cell replacement therapies.
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PubMed
高影响因子
MATERIALS LETTERS
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2022
·
IF 3.574
K.P. Li,Z.Z. Liu,Y.Q. Zhang,X.B. Yang,B. Zhou,Z.X. Xie,Z.Q. Duan,Y.M. Hu
The most used counter electrodes (CEs) in dye-sensitized solar cells (DSCs) are made of platinum (Pt). However, the cost of Pt CEs is expensive. In addition, the poor corrosion resistance of Pt in liquid electrolytes hinders commercialization of DSCs. Sulfides are potential CE materials due to their excellent catalytic performance and low cost. Nanocrystalline Cu 2 Cu 1-x-y Fe x Mn y SnS 4 (CCFMTS) CEs were fabricated using Fe and Mn co-alloyed Cu 3 SnS 4 (CTS) by an easy process of a spin-coating coupled with a post annealing. Electrochemical and photovoltaic properties of the DSCs assembled with the CCFMTS CEs were analyzed by EIS, Tafel and J-V tests. Electrochemical results show that series resistance ( R s ) and charge transfer impedance ( R ct ) at the CE/electrolyte interface of the cells decreased by 21.68% compared with the cell with unalloyed CTS CE, while exchange current density ( J 0 ) and limiting diffusion current density ( J lim ) were increased, which indicates conductivity and electrocatalytic activity of the CEs were improved after the co-alloying. As a consequence, the maximum actual output power ( P max ) of the cells was enhanced. In the optimal case, photovoltaic conversion efficiency (PCE) of 7.16% was achieved which is 84.83% of that of the cell with Pt CE.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2022
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IF 7.139
Shaojie Shi,Yifei Wang,Biaolong Wang,Fan Wu,Yange Suo,Zhiguo Zhang,Yousheng Xu
Rational design of efficient, cost-effective electrocatalyst towards oxygen reduction reaction (ORR) is of vital importance to the wide application of polymer electrolyte membrane fuel cells. In this work, a novel and simple Na 2 SO 4 -assisted pyrolysis strategy with ZIF-12 as the precursor is reported for the synthesis of cobalt, sulfur, nitrogen, co-doped carbon (termed as CoSNC- x Na 2 SO 4 -T) materials towards ORR. Different from CoNC-800 derived from pure ZIF-12, with the presence of Na 2 SO 4 , the derived CoSNC-0.5Na 2 SO 4 -800 material exhibits layered flake morphology with hierarchical meso-microporous structure. Besides, CoSNC-0.5Na 2 SO 4 -800 material shows higher content of pyridinic-N and graphitic-N, higher relative intensity of Co-N x , higher content of carbon defect, as well as larger specific surface area in comparison with CoNC-800, which results in higher activity of CoSNC-0.5Na 2 SO 4 -800. The CoSNC-0.5Na 2 SO 4 -800 material displays a half-wave potential of 0.88 V, which is superior to that of commercial Pt/C (half-wave potential being 0.86 V). Moreover, CoSNC-0.5Na 2 SO 4 -800 demonstrates a better durability compared with Pt/C. The pyrolysis temperature and the amount of Na 2 SO 4 are found to affect the physiochemical properties and electrochemical performance of the CoSNC- x Na 2 SO 4 -T materials. This work not only provides a facile and novel synthesis approach for the preparation of highly active Co, S, N co-doped carbon materials for ORR, but also disclosing the key structure properties for enhancing the performance of these catalysts.
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Food Bioscience
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2022
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IF 5.318
Xuan Chen,Jinwen Yu,Liufeng Zheng,Zeyuan Deng,Hongyan Li
Quercetin and lycopene are strong dietary antioxidants that often co-exist in foods . Here, the cardiac and neuroprotective effects of quercetin and lycopene combination were analyzed in d -galactose-induced oxidative stress in mice. ICR mice were divided into control group, d -galactose group (D-GAL), quercetin treatment (Q45: 45 mg kg −1 d −1 quercetin, Q60: 60 mg kg −1 d −1 quercetin), lycopene treatment (15 mg kg −1 d −1 lycopene), and M groups (45 mg kg −1 d −1 quercetin+15 mg kg −1 d −1 lycopene). Mice were given quercetin, lycopene, and their combination through oral gavage for 6 weeks. They were injected with d -galactose (150 mg kg −1 d −1 ) simultaneously except for the control group. Results showed that the quercetin-lycopene combination could ameliorate histopathological injuries in the heart and hippocampus. They significantly decreased the serum and heart malonaldehyde (MDA) levels, heart 4-Hydroxynonenal (4-HNE) levels, and increased the activity of serum and heart superoxide dismutase (SOD), catalase (CAT), and the hippocampal SOD and CAT mRNA level. Quercetin-lycopene combination exhibited anti-inflammation effects by reducing inflammatory genes such as cyclooxygenase-2 (COX-2) and interleukin-1β (IL-1β). The heart and hippocampal mRNA level of nuclear factor erythroid 2-related factor 2 (Nrf2) expression was up-regulated, and the antioxidant genes related to Nrf2 including heme oxygenase-1 (HO-1), NAD(P)H Quinone Dehydrogenase 1 (NQO1) were elevated. Quercetin-lycopene combination significantly promoted the mRNA level of deacetylase sirtuin-1 (SIRT1), increased 3.3-fold and 3-fold SIRT1 expression in the heart and hippocampus, respectively. They could bind SIRT1 at the active site predicted by molecular docking . These results suggested that they may interact with SIRT1 to activate Nrf2, inhibit pro-inflammatory factors, and prevent oxidative stress in D-GAL-induced mice.
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