JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2016
·Vol. 16
·期 2
·1871-1882
·
IF 1.338
Shi Haowei,Yang Junya,Zhu Lizhong,Yang Yuxiang,Yuan Hongming,Yang Yubing,Liu Xiangnong
In this paper, the chain-like core–shell structure Fe3O4@SiO2@Chitosan composite nanoparticles were synthesized by a two-step coating and following crosslinking glutaraldehyde on chitosan shell. The composite particles showed nearly monodisperse
105 sized particles with a core diameter of 80 nm and chitosan shell thickness of 12 nm. The synthesis conditions of the product were studied, and the morphology and properties of the composite nanoparticles were characterized by IR, XRD, TEM, SEM, EDS and VSM. The adsorption properties of
Hg2+, Pb2+ or Cu2+ ions on Fe3O4, Fe3 O4@SiO2 and the composite particles were in detail studied using the colorimetric method based on forming colored mercuric dithizone, rhodamine-Pb2+ complex and DDTC-Cu(2+)
complex. The results showed, adsorption isotherm, kinetics and separation coefficient of heavy metal ions on these three magnetic nanoparticles were concerned with pH, metal ions’ electronic configuration, silica coating and chitosan shell respectively. In addition, the recycle efficiency
was also studied. The findings demonstrated that Fe3O4@SiO2@Chitosan composite nanoparticles have great application value in the adsorption and separation of heavy metal ions.
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高影响因子
KINETICS AND CATALYSIS
·
2020
·Vol. 61
·期 3
·480-485
·
IF 0.934
Zhong S.
Abstract Nanofibers are attractive supporting matrices for catalytically active metallic catalysts. Herein, palladium species were successfully incorporated into the modified chitosan/poly(ethylene oxide)/maleic acid nanofibers by electrospinning. Then, the hybrid nanofibers were thermally cross-linked at elevated temperature to improve stable behavior in solution. X-ray diffraction and transmission electron microscopy characterizations show that the palladium nanoparticles are dispersed uniformly inside the hybrid nanofibers. This novel hybrid nanofiber mat displayed high catalytic activity for the Sonogashira coupling reaction of phenyl acetylene with aromatic iodides under copper free condition with moderate to excellent yields. Moreover, this nanofiber mat could be reused 10 times with little activity loss. Thus, we have proposed a facile way to prepare highly active and stable heterogeneous palladium catalyst.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Meiling Lian,Xu Chen,Xuejiao Liu,Zongchun Yi,Wensheng Yang
A novel peptide nanotube and chitosan composite (PNT–CS) is prepared by self-assembly of dipeptide monomers in a CS aqueous solution. A scanning electron microscopy image showed that the composite had a three-dimensional (3D) network structure. Contact angle analysis indicated good hydrophilicity of the PNT–CS. X-ray diffraction patterns and FT-IR spectra revealed that the basical crystallinity properties and assembled manner of the PNTs in the composite could be maintained. Electrochemical characterization demonstrated that the PNT–CS had good conductivity and excellent stability during the electrochemical measurements. The composite combined the advantages of the two constituent materials and was further employed as an electrochemical cytosensor for the detection of cancer cells (K562). The linear range from 5 × 10 3 to 5 × 10 7 cells mL −1 with a detection limit of 630 cells mL −1 was obtained at the PNT–CS-modified electrodes using the electrochemical impedance method. These results are comparable with the previously reported cytosensors based on conventional nanomaterials. Nevertheless, the present method is very simple and suitable for down-up fabrication. The combination of the electrochemical properties, easy preparation, and excellent biocompatibility makes the PNT–CS a promising platform for next generation cytosensors.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 36
·15459-15466
·
IF 3.288
Lijuan Liu,Yu Ma,Weiting Yang,Chen Chen,Meiling Li,Duoyu Lin,Qinhe Pan
One of the challenges to sustainability is to efficiently and conveniently remove organic dyes from wastewater. Herein, a light ZIF-8@chitosan (CS) composite sponge with bulk density of 0.18 g cm−3 was prepared by an in situ method. The composite sponge possesses a three-dimensional porous structure with abundant chelating sites, which can efficiently and selectively remove congo red (CR). The maximum adsorption capacity (987.01 mg g−1) is higher than most chitosan-based adsorbents. High selective adsorption towards CR over other dyes is also demonstrated. Over 90% adsorption capacity was retained after five adsorption–desorption cycles. In addition, a column-mounted equipment for fixed-bed cycle wastewater treatment was assembled with a freestanding ZIF-8@CS sponge, which exhibited high CR removal efficiency of 99%. Based on the systematic spectroscopy characterization, the dominant role in the superior adsorption performance is attributed to the electrostatic interactions, hydrogen bonds, π–π stacking and metal coordinating interaction between the ZIF-8@CS sponge and CR.
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POLYMER TESTING
·
2019
·
IF 2.943
Lian Xing,Ye Ma,Huaping Tan,Guoliang Yuan,Shengke Li,Jianliang Li,Yang Jia,Tianle Zhou,Xiaohong Niu,Xiaohong Hu
Transparent and flexible alginate-based membranes containing antibacterial drugs were prepared by a casting/solvent evaporation method from alginate solution mixed with chitosan floccule (CSF) and oxidized sodium alginate (OAlg). To improve the properties of the membranes, CSF and OAlg were added to the alginate solution in different ratios. The mechanism of membrane formation is attributed to two aspects: Schiff-base cross-linking between CSF and OAlg; ion cross-linking between sodium alginate and CaCl 2 . The results showed that the incorporation of CSF and OAlg had a significant effect on the properties of the alginate membrane. With the change in the ratio between CSF and OAlg, the tensile strength , swelling rate, water vapor permeability, wettability and degradation stability of the membranes were significantly changed. In order to enhance the anti-bacterial properties, clindamycin (DA) and silver sulfadiazine (AgSD), which represent water-soluble and water-insoluble drug models, were integrated into the membrane, respectively. The results of controlled release effects and inhibition zones indicate that the alginate membranes containing drugs have a promising future in treatment of bacterial infection as wound dressing.
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高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2018
·Vol. 99
·期 4
·1596-1603
·
IF 2.379
Rui Yang,Yu Jiang,Lili Xiu,Jianying Huang
BACKGROUND Soybeans are popularly known as a healthy food in many Asian countries and are mostly consumed as sprouts. The present study aimed to investigate the potential applications of chitosan as a natural growth regulator of soybean sprouts, as well as to determine the variation and composition of nutrients and anti-nutrients of soybean sprouts pre-soaked in different concentrations of chitosan solutions. RESULTS The hypocotyl length and fresh weight of the soybean sprouts could be positively affected by chitosan treatment. The content changes of bioactive products in chitosan-soaked soybean sprouts were dependent on the concentration of chitosan and germination time. Additionally, the lowest phytic acid content was observed in 8 g kg −1 chitosan-treated soybean sprouts, and the phytic acid content values after 5 days of germination was 1.56 g kg −1 , which was decreased by 79.0% compared to the value in ungerminated soybean. CONCLUSION Chitosan pre-soaking can increase the hypocotyl length and fresh weight of soybean sprouts and also positively effect the content of bioactive products in sprouts, whereas phytic acid can be partially removed, thereby leading to the enhancement of product quality. Chitosan pre-soaking is an alternative technology for the production of low-cost functional foods, where the dose of chitosan is a key factor. © 2018 Society of Chemical Industry
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RSC Advances
·
2015
·Vol. 5
·期 47
·37640-37647
·
IF 3.84
Haiyue Gong,Yiming Li,Mutai Bao,Dong Lv,Zhining Wang
The effective emulsification of oil and retention of the stability of this emulsion in sea water is an important requirement for the remediation process following a marine oil spill. To identify alternate dispersants for emulsifying oil following a spill, we investigated oil-in-water emulsions stabilized by self-assembled complexes of a hydrophilic petroleum hydrocarbon degrading bacteria, Bacillus cereus S-1, with the linear polysaccharide chitosan. We found that the addition of chitosan improves the ability of hydrophilic Bacillus cereus S-1 to function as an effective emulsifier. The self-assembled complex of Bacillus cereus S-1 and chitosan is able to adsorb on the interface and stabilize oil-in-water emulsions for months. Confocal laser scanning microscope (CLSM) imagings and SEM results showed that the oil-in-water emulsions were stable against coalescence by formation of a thin film of bacteria–chitosan complex. Bacillus cereus S-1 associated with chitosan in the aqueous phase gave rise to a network, which was also responsible for the emulsion stability. The ability of this complex work in seawater was still very effective. In addition to stabilization, the addition of chitosan dramatically enhanced the oil degradation rate of Bacillus cereus S-1. Due to the sustainability and low environmental impact of chitosan and petroleum hydrocarbon degrading bacteria, this is an environmentally friendly and inexpensive way to treat marine oil spills.
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高影响因子
Biomaterials Science
·
2021
·Vol. 9
·期 9
·3319-3333
·
IF 6.843
Mengyu Yao,Qingxia Zou,Wenwu Zou,Zhenze Xie,Zhihao Li,Xiujuan Zhao,Chang Du
The bifunctional tissue engineering scaffold with anti-tumor and bone repair properties is promising for the therapy of bone tumor where large bone defects often occur. In this study, hydroxyapatite (HA), poly(dopamine) (PDA), and carboxymethyl chitosan (CMCS) composite scaffolds were prepared by the 3D-printing technology. PDA significantly improved the rheological properties of the slurry for molding, mechanical properties, surface relative potential, and water absorption of composite scaffolds. The osteogenic properties of HA/PDA/CMCS composite scaffolds were evaluated by the cell experiment in vitro. The photothermal properties and anti-tumor effects of the scaffolds in vivo were assessed by the tumor model in nude mice. HA/PDA/CMCS composite scaffolds could promote more osteogenic differentiation of mouse bone marrow stromal cells (mBMSCs) than scaffolds without PDA in vitro and the effect was not hindered by the photothermal process. The PDA-modified composite scaffold had excellent photothermal properties. Cell experiments showed that scaffolds with PDA under irradiation could suppress the tumor effectively. In vivo anti-tumor effects in nude mice indicated that the HA/PDA/CMCS composite scaffold promoted cell apoptosis/necrosis by the direct photothermal effect. Vascular injury was developed subsequently, which lead to the suppression of tumor cell proliferation due to hypoxia-ischemia. HA/PDA/CMCS composite scaffolds with multiple effects have great potential application in bone tumor therapy.
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高影响因子
Journal of Biomedical Nanotechnology
·
2016
·Vol. 12
·期 8
·1688-1698
·
IF 3.929
Zhang Xueqiong,Zhang Hong,Yin Liangquan,Hu Rui,Qiu Tong,Yin Yihua,Xiong Xiong,Zheng Hua,Wang Qun
Nanoparticles, such as polymeric micelles, are currently regarded as effective drug delivery vehicles. In this study, a series of carboxymethyl chitosan/daunorubicin (CMCS/DNR) conjugates with macromolecular carriers of different molecular weights (MWs) were prepared and structurally
characterized by Fourier transform infrared spectroscopy (FT-IR) and 1H-NMR spectroscopy. The results indicated that the MWs of the carriers greatly influenced the drug loading capacity. DNR was conjugated to the polymer via an acid-sensitive hydrazone linkage susceptible to hydrolysis
at pH 5–6, thereby enabling intracellular DNR release. In aqueous media, the conjugates spontaneously formed nano-sized particles with core–shell structures (CMCS and DNR as the shell and core, respectively). Dynamic light scattering (DLS) and trans-mission electron microscopy
(TEM) indicated that the prepared nanoparticles were spherical in shape with diameters of 100–200 nm and had a slight negative surface charge. In addition, in vitro drug release studies demonstrated that the micelles were highly sensitive to mild acidic conditions (pH 5.0) but
remained reasonably stable at pH 6.5 and pH 7.4. Importantly, cell counting kit-8 (CCK-8) assays demonstrated that DNR-conjugated nanoparticles exerted a cytotoxic effect on HeLa cells, with the IC50 being approximately 2 times higher than that of free-DNR. Furthermore, confocal
laser scanning microscopy (CLSM) revealed that the CMCS-hyd-DNR nanosystem could efficiently deliver and release DNR in the nuclei of cancer cells. Taken together, the developed CMCS based pH-sensitive nanosystem may be a potential drug delivery vehicle for cancer therapy.
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高影响因子
BIOMACROMOLECULES
·
2021
·
IF 6.988
Enci Mei,Cunguo Chen,Chunxiao Li,Xiaoxia Ding,Jiashe Chen,Qiaoer Xi,Sen Zhou,Jingjing Liu,Zhiming Li
Combined therapy provides a more effective method in the treatment of tumors and becomes a research hotspot. To improve treatment outcomes and reduce serious side effects, hydrogel-based local delivery was developed herein to form a drug depot in suit to eliminate tumors. Indocyanine green and imiquimod were coencapsulated in the novel temperature-sensitive chitosan hydrogel. After intratumoral injection of the hydrogel, indocyanine green that accumulated in the tumor area could induce thermal ablation of primary tumors under laser irradiation. In the presence of imiquimod, the immune effects increased the probability of complete ablation of primary tumors and inhibition of metastases. Combined with cyclophosphamide, the enhanced immunological responses would further inhibit tumors and prolong the survival time. In a word, this work offered an excellent local delivery platform that enabled a remarkable combined antitumor strategy and achieved synergistic therapeutic effects.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Xiaoyong Qiu,Jun Huang,Hui Wang,Yulu Qi,Jiwei Cui,Jingcheng Hao
Hypothesis Water contamination from heavy metal ions is a major global environmental concern. Adsorbents based on biomaterials have been demonstrated to possess remarkable removal efficiency for metal ions, but the adsorption model of biosorbents is not clear and much efforts should be devoted to study the adsorption behaviors and understand the adsorption mechanism. Experiments The multifunctional rhodamine-modified chitosan (RMC) hydrogel for Hg 2+ adsorption with fluorescent turn-ON properties was fabricated through grafting the rhodamine-modified poly (ethylene glycol) benzaldehyde (RM-PEG) onto the hydrogel network serving as the fluorescence/colorimetric sensing receptor. The adsorption behaviors and colorimetric sensing mechanism of RMC hydrogel towards Hg 2+ were investigated in detail. Findings RMC hydrogel can remove more than 96.5% of Hg 2+ from aqueous solution with significant fluorescence response and colorimetric change. The high adsorption selectivity and colorimetric sensing mechanism of RMC hydrogel towards Hg 2+ can be explained by the hard and soft acid/base (HSAB) theory. The O atom in hydroxyl and carbonyl groups together with the N atom in amine/imine groups of RMC hydrogel play a vital role in the adsorption of Hg 2+ , while the colorimetric response and fluorescence enhancement of the hydrogel after adsorption are attributed to the specific spiro-lactam structure of rhodamine moieties. The adsorption isotherms and kinetics were investigated and well described by Freundlich isotherm and pseudo-second-order kinetic model . Furthermore, RM-PEG showed low cytotoxicity towards mouse embryonic fibroblast cells and RMC hydrogel can be used as a fluorescent pH indicator from 4.2 to 7.4, demonstrating the potential applications of RMC hydrogel in biological diagnosis.
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高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Lin-Kun Sun,Tian Du,Pei-Ru Zhou,Yu-Cang Zhang,Yan-Zhen Zheng
Developing appropriate packaging technologies is crucial for maintaining shrimp quality and reducing potential food safety risks. Meanwhile, concerns over the environmental impact of petroleum-based plastics have accelerated the development of biodegradable packaging from renewable resources. In this study, bioactive chitosan (CS) composite films were developed by incorporating tea stem extract obtained using a choline chloride–glycerol-based natural deep eutectic solvent (NADES). The DES tea stem extract (DTSE) served a dual function as a plasticizer and a bioactive agent. Results showed that DTSE incorporation improved film flexibility (maximum EAB of 173%), enhanced antioxidant capacity (maximum DPPH scavenging rate of 94.8%), and provided moderate UV barrier properties without compromising hydrophobicity. Application of the CS/DTSE composite films in shrimp meat preservation demonstrated significant efficacy: the films effectively maintained shrimp meat appearance, slowed pH increase, reduced weight loss, suppressed lipid oxidation and protein degradation, inhibited microbial growth, and minimized off-odor development, thereby significantly extending shrimp shelf life by 2–3 days. These findings indicate that NADES-extracted tea polyphenols can serve as a sustainable and multifunctional additive, providing an effective strategy for the development of active packaging materials that extend the shelf life of perishable seafood products while valorizing tea stem waste.
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