ACS Nano
·
2024
·
IF 15.8
Wenying Li,Dong Chen,Yanmei Zhu,Qiange Ye,Yang Hua,Ping Jiang,Ying Xiang,Yuejie Xu,Yinya Pan,Hua Yang,Yichun Ma,Hang Xu,Cheng Zhao,Chang Zheng,Changrong Chen,Yun Zhu,Guifang Xu
Current therapies primarily targeting inflammation often fail to address the root relationship between intestinal mucosal integrity and the resulting dysregulated cell death and ensuing inflammation in ulcerative colitis (UC). First, UC tissues from human and mice models in this article both emphasize the crucial role of Gasdermin E (GSDME)-mediated pyroptosis in intestinal epithelial cells (IECs) as it contributes to colitis by releasing proinflammatory cytokines, thereby compromising the intestinal barrier. Then, 4-octyl-itaconate (4-OI), exhibiting potential for anti-inflammatory activity in inhibiting pyroptosis, was encapsulated by butyrate-modified liposome (4-OI/BLipo) to target delivery for IECs. In brief, 4-OI/BLipo exhibited preferential accumulation in inflamed colonic epithelium, attributed to over 95% of butyrate being produced and absorbed in the colon. As expected, epithelium barriers were restored significantly by alleviating GSDME-mediated pyroptosis in colitis. Accordingly, the permeability of IECs was restored, and the resulting inflammation, mucosal epithelium, and balance of gut flora were reprogrammed, which offers a hopeful approach to the effective management of UC.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2024
·Vol. 141
·期 29
·e55670
·
IF 2.7
Jinyun Cui,Huaping Wang,Xinyi Chen,Ze Kan,Zhibo Li
Poly(butylene-adipate-co-terephthalate) (PBAT) is recognized for its advantages as a biodegradable thermoplastic polyester. However, its application is often limited due to low strength and poor processability. In contrast, poly(4-hydroxybutyrate) (P4HB) emerges as a fully biodegradable polyester characterized by high strength, excellent toughness, and facile processing. In this study, P4HB was employed to reinforce PBAT, and glycidyl methacrylate grafted onto poly(4-hydroxybutyrate) (P4HB-g-GMA) was introduced as an effective compatibilizer to address their inherent incompatibility. The study explored the influence of P4HB-g-GMA content on the mechanical, thermal, morphological, and rheological properties of the blends. The findings revealed that P4HB-g-GMA significantly enhanced the compatibility, mechanical properties, and melt strength of PBAT/P4HB blends. Furthermore, various PBAT/P4HB foams were prepared through a batch foaming process, employing supercritical CO 2 as a physical foaming agent. The volume expansion ratio and cell size of PBAT/P4HB foams increased with higher levels of the compatibilizer.
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高影响因子
JOURNAL OF CHEMICAL EDUCATION
·
2024
·
IF 2.5
Huifa Han,Yali Qin,Fan Wang,Ning Ding,Fang Fang,Lihong Hu,Hongming Jin,Yinan Zhang
Electrophilic aromatic substitution (SEAr) and nucleophilic aromatic substitution (SNAr) reactions are among the most valuable reactions in the conversion of aromatic rings. While these reactions are typically covered in separate experiments in undergraduate organic courses, a continuous experimental setup elucidating both SEAr and SNAr processes remains unexplored in the literature for undergraduate laboratories. We herein described a two-step experimental design to cascade the SEAr and SNAr reactions, aiding students in better understanding the similarities and differences of these conversions as well as introducing the concept of umpolung. The experiment also reinforces students’ proficiency in fundamental organic synthesis techniques and workup procedures, such as TLC analysis, chromatography purification, recrystallization, and handling LRMS and NMR.
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高影响因子
POLYHEDRON
·
2024
·
IF 2.4
Zhengwei Wu,Jiawen Bao,Hongyang Zhang,Yingying Luo,Zhonglu You
Molecular nanoclusters comprising heterometallic Ni-Zn cores are an interesting class of compounds. In this paper, five novel Ni II -Zn II complexes [Ni 2 Zn 2 ClL 3 (HL) 3 ]·0·.25H 2 O ( 1 ), [Ni 2 Zn 2 BrL 3 (HL) 3 ]·0·.25H 2 O ( 2 ), [Ni 2 Zn 2 Br 2 L 2 (N 3 ) 2 (MeOH) 2 ]·2MeOH ( 3 ), [Ni 2 Zn 2 I 2 L 2 (N 3 ) 2 (MeOH) 2 ]·2MeOH ( 4 ), and [Ni 2 Zn 2 I 2 L 2 (N 3 ) 2 (DMF) 2 ] ( 5 ), were prepared from the Schiff base 2-(3-ethoxy-2-hydroxybenzylideneamino)-4-methylphenol (H 2 L). The complexes have been characterized by elemental analysis, IR, UV–Vis spectra. Molecular structures of the complexes have been determined by single crystal X-ray determination. In complexes 1 and 2 , three of the Schiff bases coordinate to the metal atoms via ether oxygen, imino nitrogen and two phenolate oxygen atoms, while the fourth one coordinates through ether oxygen, imino nitrogen and one phenolate oxygen atoms. In complexes 3 , 4 and 5 , all the donor atoms in the Schiff base ligands participate in coordination. The Ni and Zn atoms in the complexes are in octahedral and trigonal bipyramidal coordination, respectively. The anions of the metal salts and the azide anion, as well as methanol and DMF molecules furnish the coordination sphere. The compounds were evaluated for their antibacterial activities on Bacillus subtilis , Staphylococcus aureus , Escherichia coli and Pseudomonas fluorescens , and antifungal activities on Candida albicans and Aspergillus niger . Interestingly, the complexes have effective activities against Bacillus subtilis and Staphylococcus aureus .
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高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Yuting Sun,Bin Yao,Yuhong Jiang,Yongfeng Li,Xiaobo Du,Zhanhui Ding,Jiayong Zhang,Chunkai Wang,Ding Ma,Mengge Li,Yan Zhu,Xiaofei Sun,Ning Ding,Liyuan Shi
It is well known that the improvement of crystal quality and photoelectric properties of Cu2ZnSn(S,Se)4 (CZTSSe) is one of the key issues in enhancing power conversion efficiency (PCE). To resolve this problem, we selected Li2CO3 as a Li source to prepare Li-doped CZTSSe by annealing Li-doped Cu2ZnSnS4 (CZTS) precursor films in air, followed by selenization (CZTSSe-Li-A). It is interesting that the air annealing leads to the incorporation of Li and O into CZTSSe in the form of Li-O pairs, which improves the crystal quality and absorption coefficient (α) of CZTSSe-Li-A and decreases its hole concentration and resistivity compared with Li-doped CZTSSe prepared using Li-doped CZTS that is not annealed in air (CZTSSe-Li). By optimizing Li doping concentration, annealing temperature and time, the highest PCE of CZTSSe-Li-A solar cell without MgF anti-reflection layer reaches 11.13%, which is larger than the highest PCE of CZTSSe-Li solar cell (10.21%). Quantitative analysis indicates that the increased PCE of CZTSSe-Li-A solar cell compared to CZTSSe-Li solar cell is mainly attributed to the decrease in reverse saturation current density (J0) and series resistance (Rs) caused by thermal effect of the air annealing, followed by an increase in photogeneration density (JL) and shunt resistance (Rsh). The decreased J0 is due to a reduction in interfacial defect density, increased JL is due to increase in α and depletion region width, and decreased Rs and increased Rsh are due to improve crystal quality. This work offers a route for the improvement of PCE of CZTSSe solar cells.
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高影响因子
Journal of Water Process Engineering
·
2025
·
IF 6.7
Mei Dong,Qiguang Cao,Song Li,Kebin Li
Designing stable and efficient heterogeneous catalysts for peroxymonosulfate (PMS) activation remains a critical challenge in advanced oxidation processes. Herein, we prepared a polyvinylpyrrolidone (PVP)-modified MIL-101(Fe)@CoZn-ZIF (PVP-MCZ) core-shell nanocomposite that synergistically combined enhanced catalytic activity with exceptional stability. The PVP-MCZ catalyst achieved complete degradation of 4-nitrophenol (4-NP) (20 mg/L) within 15 min, while suppressing metal leaching (<0.5 mg/L). Comprehensive characterization (XPS, EPR) revealed a dual-pathway mechanism: (i) radical-dominated SO 4 − generation via Co 2+ /Co 3+ and Fe 2+ /Fe 3+ redox cycling, and (ii) non-radical 1 O 2 production from PMS self-decomposition. This work provides a scalable strategy to design MOF-based catalysts for sustainable water remediation.
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高影响因子
CATALYSIS LETTERS
·
2025
·Vol. 155
·期 8
·1-13
·
IF 2.4
Wumaer Mailidan,Ai Jiakun,Abdulla Rahima,Akbar Mustafa,Wang Jide
Cobalt-based composites have demonstrated promising catalytic potential for organic pollutant degradation. However, the influence of exposed basal facets on their catalytic activity remains insufficiently explored. In this study, Co@CN, Cu/Co@CN, and Zn/Co@CN composites with preferentially exposed Co(111), Cu(111)/Co(111), and Co(111)/Zn(002) facets, respectively, were synthesized via a facile hydrothermal method. The facet-dependent catalytic performance and reaction mechanisms were systematically investigated through the reduction of 4-nitrophenol (4-NP). Experimental results combined with density functional theory (DFT) calculations revealed that the Co(111) facet was identified as a critical determinant of both catalytic activity and reaction pathways. Furthermore, we also tried to reveal how the preferential growth of co-exposed facets (Cu(111)/Co(111) and Co(111)Zn(002)) modulate catalytic activity and reaction pathways. As a results, the Cu/Co@CN with preferential exposed facet Cu(111)/Co(111) achieved increasing efficiency in reducing 4-NP to 4-aminophenol (4-AP) within 90s, with a pseudo-first-order rate constant (k) of 0.720 min -1 . Revealing that the synergy between Cu(111) and Co(111) exemplifies how crystal facets synergistically influenced to catalytic activity and reaction process. Moreover, the catalysts also showed durability over six cycles. The outcomes of this study provide new insights into comprehensiveness exposed crystal plane dependent activity and the design of efficient transition-metal catalysts using the facet strategy for effective degradation of certain pollutants in wastewater. Graphical
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高影响因子
ACS Sustainable Chemistry & Engineering
·
2025
·
IF 7.3
Shuxin Wang,Hui Li,Gen Zhou,Jingmei Xu,Baoju Li,Xiangzi Wei,Zhe Wang
Traditional proton exchange membranes (PEMs), such as Nafion, often rely on perfluorosulfonic acid, posing ecological risks. To address this, sulfonated poly(arylene ether ketone sulfone) containing amino group (Am-SPAEKS) membranes were created as an eco-friendly alternative. This study further innovates by incorporating sulfonatocalix[4]arene (SC4A)-functionalized UiO-66-NH2 (SC4A@UiO-66-NH2) into Am-SPAEKS to produce ASUS-X wt % hybrid membranes. This combination not only boosts proton conductivity without sacrificing mechanical properties but also leverages the unique functionalities of supramolecular macrocycles and metal–organic frameworks (MOFs) to create efficient proton transport channels. The resultant hybrid membrane ASUS-6 wt % exhibits remarkable properties, including a swelling ratio of 16.75% at 80 °C, tensile strength of 41.08 MPa, and proton conductivity of 163.11 mS cm–1 at 80 °C and 100% RH, 89.13% higher than pristine Am-SPAEKS, with over 86% conductivity remaining after 432 h. Remarkably, the maximum power density reaches 392.73 mW cm–2, twice that of pristine Am-SPAEKS. The unique properties of supramolecular macrocycles and MOFs can provide tailored functionalities to address key challenges in PEMs applications.
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高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Xin Wang,Kaiyan Mao,Jianqing Ma,Huining Zhang,Yongxing Qian,Huixia Jin,Kefeng Zhang
Nitrogen-doping is an effective strategy for enhancing peroxymonosulfate (PMS) activation efficiency by carbon-based catalysts, yet its impact on pollutant adsorption remains largely unexplored. Here, N-doped biochar (CNC) was synthesized via pyrolysis of sodium lignosulfonate, melamine, and activated carbon. The CNC/PMS system exhibited excellent efficiency for 4-chlorophenol (4-CP) removal, following a pseudo-second-order kinetic model with an observed rate constant of 0.0134 L·mg –1 ·min –1 . This process relied on synergistic adsorption and catalytic degradation processes. N-doping improved the graphitization of the carbon skeleton and introduced defects that facilitated PMS activation via non-radical pathways. However, excessive pyridinic N reduced 4-CP adsorption due to increased hydrophilicity, emphasizing the need for balanced doping. Mechanistic analysis of the CNC/PMS/4-CP system revealed that electron transfer pathways dominated the degradation process, with C=O groups and pyrrolic N on the CNC surface serving as primary active sites. Degradation pathways of 4-CP involved hydroxylation, dechlorination, and polymerization, with many intermediates adsorbed onto CNC, thereby minimizing ecological risks. The system achieved over 95 % removal efficiency both in tap and river water and maintained effectiveness over seven cycles, demonstrating robust anti-interference capability and stability. These findings advance understanding of electron transfer pathway control and broaden N-doped biochar applications in water treatment.
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高影响因子
MOLECULAR CRYSTALS AND LIQUID CRYSTALS
·
2025
·
IF 0.7
Yang Yun-Xia,Fu Shi-Huia,Ma Xiao-Na,Guo Ying-Wa,Wu Xiang-Xiang
In this article, two novel complexes with 5-[[4-(2H-Tetrazol-5-yl)phenyl]methoxy]-1,3-benzenedicarboxylic (HL) as ligand were synthesized under solvothermal conditions: [Co2L(H2O)2]∙2H2O (1), [Zn2L(H2O)2]∙2H2O (2). However, these two complexes are very unstable because they tend to lose their water molecules under room temperature. Single crystal X-ray diffraction analysis under low temperature show that these two complexes are isomorphic and the Schleffli symbol of the topological structure is {322.416.57}{341.468.511}. Interestingly, two unique Co atoms link with one water molecules to form a binuclear cluster, then the cluster further coordinates with the organic ligand and water molecules to infinitely extend to be one-dimensional chain, and the chains are connected with four nitrogen atoms of the ligands to form a two-dimensional layer structure, which are further connected to generate the final three-dimensional framework.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Bin Du,Haoran Ye,Yincheng Wang,Ming Shen,Hui Zhou
The limited optical adsorption range and rapid recombination of photoexcited electron-hole pairs have severely hindered the development of ZnO-based photocatalysts . As macromolecular compounds, calixarenes become potential photocatalyst modifiers owing to their special molecular structures. In this work, ZnFe 2 O 4 /ZnO heterojunction photocatalysts which consist of ZnFe 2 O 4 nanoparticles and ZnO nanosheets were fabricated by simple hydrothermal reaction with the introduction of tetrasulfonatomethyl-n-hexyl calix[4]resorcinarene tetrasodium (THCRT 1 ). The synthesized ZnFe 2 O 4 /ZnO nanocomposite possesses a larger specific surface area , broader-spectrum absorption and an electronegative surface due to the addition of THCRT. Furthermore, the successful construction of ZnFe 2 O 4 /ZnO heterojunction leads to low charge transfer resistance and enhanced photocurrent density. Therefore, the THCRT-capped ZnFe 2 O 4 /ZnO composite exhibited superior adsorptive performance and removal efficiency towards Rhodamine B (RhB) and Levofloxacin hydrochloride (LH). The calcined nanocomposite degraded 95.80 % of RhB (10 mg L −1 ) and 97.86 % of LH (20 mg L −1 ) after 120 min under simulated sunlight illumination at a minimal catalyst dosage of 0 .1 g L −1 . Additionally, to determine the band structures , the band gaps, valence band positions and the Fermi levels were measured by Tauc plot, valence band x-ray photoelectron spectroscopy (XPS-Vb) and Mott-Schottky plot, respectively. Finally, based on the band structure results, we proposed a potential photocatalytic mechanism of n-n heterojunction. This work offers a promising prospect in the treatment of sewage containing organic contaminants.
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高影响因子
Catalysts
·
2024
·Vol. 14
·期 3
·183
·
IF 3.8
Jiarong Ma,Run Zhou,Yu Tu,Ruixin Ma,Daimei Chen,Hao Ding
Ni3Si2O5(OH)4rods (NS) were synthesized via a hydrothermal method, employing natural wollastonite as a template. The hierarchical Ni3Si2O5(OH)4rods exhibited vertically oriented nanosheets, resulting in a substantial increase in the specific surface area (from 2.24 m2/g to 178.4 m2/g). Subsequently, a CdS/Ni3Si2O5(OH)4composite photocatalyst (CdS/NS) was prepared using a chemical deposition method. CdS was uniformly loaded onto the surface of the Ni3Si2O5(OH)4nanosheets, successfully forming a heterojunction with Ni3Si2O5(OH)4. The CdS/NS photocatalyst in the presence of lactic acid as a sacrificial agent demonstrated an impressive H2production rate of 4.05 mmol h−1g−1, around 40 times higher than pure CdS. The photocorrosion of CdS was effectively solved after loading. After four cycles, the performance of CdS/NS remained stable, showing the potential for sustainable applications. After photoexcitation, electrons moved from Ni3Si2O5(OH)4to the valence band of CdS, where they interacted with the holes via an enhanced interface contact. Simultaneously, electrons in CdS transitioned to its conduction band, facilitating hydrogenation. The enhanced performance was attributed to the improved CdS dispersion by Ni3Si2O5(OH)4loading and efficient photogenerated carrier separation through the heterojunction formation. This work provides new perspectives for broadening the applications of mineral materials and developing heterojunction photocatalysts with good dispersibility and recyclability.
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高影响因子
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