Polymer Chemistry
·
2013
·Vol. 4
·期 6
·2164-2167
·
IF 5.231
Yang Yuan,Guanghui Zhang,Yang Li,Guoliang Zhang,Fengbao Zhang,Xiaobin Fan
Poly(amidoamine) modified graphene oxide was prepared via a grafting-from method and characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and atomic force microscopy (AFM). Evaluation of its adsorption capacity for heavy metal ions demonstrated that the poly(amidoamine) modified graphene oxide had superior adsorption ability towards heavy metal ions such as Cu2+, Zn2+, Fe3+, Pb2+ and Cr3+.
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2012
·
IF 3.832
Huanshun Yin,Zhenning Xu,Mo Wang,Xueping Zhang,Shiyun Ai
DNA methylation plays a crucial role in eukaryotes’ growth and development, which is catalyzed by DNA methyltransferase (MTase). DNA MTase can transfer the methyl group to the C-5 position of cytosine in eukaryote from the methyl group donor of S -adenosylmethionine (SAM). Here, we developed a sensitive electrochemical method for assay of DNA methyltransferase (MTase) activity and screening of DNA MTase inhibitor without labeling processes. This strategy is mainly based on the change of reduction peak current of ferrocenecarboxylic acid (FcA), which is conjugated to the biosensor as electrochemical activity probe. The reduction current of FcA was enhanced with increasing DNA MTase concentration from 0.1 to 70 unit/mL, where the linear range of the concentration was from 0.1 to 1 unit/mL and 1 to 50 unit/mL with the detection limit of 0.045 unit/mL (S/N = 3). The investigation results demonstrated that the activity of DNA MTase depended on MTase concentration and incubation time. Inhibition experiment indicated that fisetin had good inhibition activity on DNA MTase in the presence of catechol- O -methyltransferase. This electrochemical method had the potential application in the screening of DNA MTase inhibitor, provided valuable information for anti-cancer drug research and also for cancer therapy.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2014
·Vol. 132
·期 11
·
IF 1.64
Jinbo Jin,Dongqing Liu,Dandan Zhang,Yuhang Yin,Xinyu Zhao,Yufeng Zhang
A hydrophilic compound, taurine, was investigated as an additive in the interfacial polymerization between piperazine (PIP) and trimesoyl chloride (TMC) to prepare thin-film composite (TFC) membranes. The resulting membranes were characterized by X-ray photoelectron spectroscopy and attenuated total reflectance–Fourier transform infrared spectroscopy. The morphology and hydrophilicity of the membranes were investigated through scanning electronic microscopy and water contact angle measurements. The separation performance of the TFC membranes was investigated through water flux and salt rejection tests. The protein-fouling resistance of the films was evaluated by water recovery rate measurements after the treatment of bovine serum albumin. The membrane containing 0.2 wt % taurine showed the best performance of 92% MgSO 4 rejection at a flux of 31 L m −2 h −1 and better antifouling properties than the PIP–TMC membranes. An appropriately low concentration of taurine showed the same MgSO 4 rejection as the PIP–TMC membranes but a better fouling resistance performance. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 41620.
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Polymeric Materials and Polymeric Biomaterials
·
2014
·
IF 2.784
Dong Zheng,Yuan
Yuan An,Shuhua Yang,Wei Wu,Weihua Xu,Guohui Liu,Cao Yang,Yang Dan,Zushun Xu,Shuilin Wu
Amphiphilic copolymers P(PBA)-g-P(PEG) containing poly(phenylboronic acid) (PPBA) and poly(ethylene glycol) (PEG) side chains were synthesized by copolymerization of 4-vinylphenylboronic acid (PBA) and poly(ethylene glycol) methyl ether methacrylate. The surface tension results showed that the critical micelle concentration (CMC) of P(PBA)-g-P(PEG) was 0.09 g/L. TEM revealed that these copolymers self-assembled into regular sphere micelles above CMC. The photon correlation spectroscopy suggested that they had unique performance of thermo-induced self-assembly. Above critical micelle temperature, they self-assembled into monodisperse micelles with thermosensitivity. Hydrodynamic diameters of these micelles increased dramatically in the presence of glucose. The glucose-regulated drug release behavior was observed through UV-vis spectroscopy.
✓ 已验证
产品关联
DOI
高影响因子
THERMOCHIMICA ACTA
·
2014
·
IF 2.105
Haifeng Jiang,Hui Li,Cheng Zan,Fuqiang Wang,Qianpeng Yang,Lin Shi
Oil-based nanofluids were prepared by dispersing copper nanoparticles into a high-temperature synthetic oil using a two-step method. The nanofluid stability was evaluated by measuring the effective thermal conductivity over time. The thermophysical properties of the nanofluids were investigated by measuring the effective thermal conductivity up to a maximum temperature of 210 °C using the transient hot wire method. The thermal conductivity was increased with increasing Cu nanoparticle volume fraction and decreased with temperature between 30 and 210 °C. A maximum thermal conductivity enhancement of about 18% was obtained at 30 °C with the 0.02 volume fraction of Cu nanoparticles. The experimental data below 150 °C compares well with predictions of the Jang and Choi model. Above 150 °C, the effective thermal conductivity enhancement is much lower than predicted by the model, so new mechanisms are needed to explain this phenomenon.
✓ 已验证
DOI
高影响因子
NANOTECHNOLOGY
·
2015
·Vol. 26
·期 49
·495102
·
IF 3.821
Ming-Hao Yao,Jie Yang,Ji-Tao Song,Lin Zhang,Bi-Yun Fang,Dong-Hui Zhao,Rui-Xue Xia,Rui-Mei Jin,Yuan-Di Zhao,Bo Liu
Quantum dot (QD)–polypeptide probes have been developed through the specific metal-affinity interaction between polypeptides appended with N-terminal polyhistidine sequences and CdSe/ZnS core–shell QDs. The size and charge of a QD–polypeptide can be tuned by using different coiled-coil polypeptides. Compared to glutathione-capped QDs (QD–GSH), QD–polypeptide probes showed an approximately two- to three-fold luminescence increase, and the luminescence increase was not obviously related to the charge of the polypeptide. QD–polypeptide probes with different charge have a great effect on nonspecific cellular uptake. QD–polypeptide probes with negative charge exhibited lower nonspecific cellular uptake in comparison to the QD–GSH, while positively charged QD–polypeptide probes presented higher cellular uptake than the QD–GSH. A targeted QD–ARGD probe can obviously increase targeted cellular uptake in αvβ3 overexpressing HeLa cells compared to QD–A. In addition, QD–polypeptide probes showed lower in vitro cytotoxicity compared to the original QDs. These results demonstrate that these QD–polypeptide probes with high specific cellular uptake, high fluorescence intensity and low background noise are expected to have great potential applications in targeted cell imaging.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYST
·
2015
·Vol. 141
·期 3
·1077-1082
·
IF 4.107
Xiuyun Wang,Min Xi,Mengmeng Guo,Fangmeng Sheng,Guang Xiao,Shuo Wu,Shunichi Uchiyama,Hiroaki Matsuura
In this contribution, a very simple and reliable strategy based on the easy modification of a glassy carbon electrode (GCE) by pre-electrolyzing GCE in ammonium carbamate aqueous solution was employed for the simultaneous determination of hydroquinone (HQ) and catechol (CC). Compared with bare GCE, the incorporation of nitrogen into the GCE surface structure improved the electrocatalytic properties of GCE towards the electro-oxidation of HQ and CC. The nitrogen-introduced GCE (N-GCE) was evaluated for the simultaneous detection of HQ and CC and the linear ranges for HQ and CC were both from 5 to 260 μM. Their detection limits were both evaluated to be 0.2 μM (S/N = 3). The present method was applied for the determination of HQ and CC in real river water samples with recoveries of 95.0–102.1%. In addition, a possible detection mechanism of HQ and CC was discussed.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Smart Materials and Structures
·
2015
·Vol. 24
·期 7
·075001
·
IF 2.502
Qingsong He,Linlin Song,Min Yu,ZhenDong Dai
We develop an ionic polymer metal-carbon nanotube composite (IPMCC) actuator composed of a multiwalled carbon nanotube (MWCNT)/Nafion membrane sandwiched between two hybrid electrodes, composed of palladium, platinum and MWCNTs. The surface morphology and cross-sectional structure of the metal-carbon nanotube hybrid electrode were observed using scanning electron microscopy (SEM). SEM investigation indicated that the MWCNT layer can adhere very well with the platinum–palladium metal electrode, fill the cracks in the metal surface, and prevent the oxidation of nanoscale platinum particles. These observations show that the surface resistance of the total electrode is retained and the stability of electrode property is maintained. The displacement, blocking force and nonlinear current versus voltage (V–I) characteristics were measured. Compared with an ionic polymer metal composite (IPMC), the IPMCC shows a more stable displacement and blocking force under 1, 1.2 and 2 V at 0.1 Hz, and 2.34–3.29 times higher effective air-operating time under 3 V at 0.1 Hz. It can be observed from the V–I characteristics that the change in shape becomes significant at amplitudes higher than 1.2 V. An equivalent circuit is used to model the nonlinear behavior of the IPMCC, in which the leakage current was taken into account and analyzed. The values of the components in the circuit are estimated and electrical behavior is simulated by using the Pspice software. Compared with the model with no consideration of the leakage current, the simulations obtained by the model considering leakage current showed better agreement with the experimental results. The impressive leakage current (20 mA), which is successfully simulated by the proposed model with the nonlinear circuit, is shown to play an important role in the total current.
✓ 已验证
产品关联
DOI
高影响因子
ChemPlusChem
·
2015
·Vol. 80
·期 9
·1435-1439
·
IF 3.026
Qin Liu,Kai Meng,Kui Ding,Yaobing Wang
Graphical Quick cleanup! When a melamine sponge was coated with polyaniline and then immersed in n -dodecylthiol, it became superhydrophobic and suitable for oil absorption (see picture). The modified sponge absorbs a broad spectrum of oil and organics efficiently with high absorption capacity, and exhibits thermal stability and excellent mechanical stability. Oil/water separation is a worldwide challenge due to frequent oil spillages, and high-performance absorbents are in high demand. In this work, a superhydrophobic sponge was fabricated by the polymerization of aniline, with subsequent simple immersion in n-dodecylthiol. The polyaniline (PANI) constructed a nanoscale rough surface on the three-dimension (3D) network of melamine sponge while n-dodecylthiol reduced surface energy, thus lead to the superhydrophobicity. This superhydrophobic sponge could absorb a broad spectrum of oil and organics efficiently, with the highest 122 times of its own weight absorption capacity. Owing to the strong mechanical elasticity inherited from the pristine melamine sponge and stable adhesion of PANI, this sponge exhibited good recyclability through squeezing. More importantly, the fabrication procedure is facile, low-cost and easily scalable. Thus, this superhydrophobic sponge is highly promising for absorption oil from water.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 26
·20155-20159
·
IF 3.84
Rui Chen,Liqun Wang
An amphiphilic hyperbranched polymer containing large amounts of pH sensitive bonds was synthesized by our group. The hydrophobic chains are hyperbranched polyacetals (HBPAs) and the hydrophilic chains are polyethylene glycols. Polyethylene glycols are attached to the hyperbranched polyacetals by the hydrazone bonds. The amphiphilic hyperbranched polymer could be assembled into micelles easily by the dialysis method. The micelles containing large amounts of pH sensitive bonds were quite fragile in pH 5.0 buffer solution but very stable in pH 7.4 buffer solution. DOX-loaded micelles were also prepared by the dialysis method. The sizes of the blanked micelle and DOX-loaded micelle were 30 nm and 35 nm, respectively. The increase of the diameter confirmed that DOX was successfully loaded into the micelle. Drug loading content and drug loading efficiencies were 2.34% and 23.4%, respectively, which was detected by the UV-VIS at the wavelength of 482 nm. The drug release behavior demonstrated that DOX was released faster in pH 5.0 buffer solution than in pH 7.4 buffer solution.
✓ 已验证
产品关联
DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2015
·Vol. 216
·期 6
·671-677
·
IF 2.616
Yuecheng Qian,Xiaojun Huang,Zhikang Xu
A green route is reported for functionalizing polyphosphazene via the thiol-ene click reaction in an aqueous medium. Poly[bis(allylamino)phosphazene] is used as the precursor polymer, which is easily dissolved in water containing 5% (v/v) phosphoric acid, but barely dissolved in other acidic aqueous solutions with the same pH value. Three thiol reagents, namely, 3-mercapto-1,2-propanediol, 2-mercaptoethoxy ethanol, and l -cysteine, are then reacted with the precursor in the phosphoric acid aqueous solutions. 1 H and 31 P NMR analyses confirm that the allyl polyphosphazene can be quantitatively modified by the mercaptans without hydrolysis degradation during the synthesis and purification processes. Moreover, these polyphosphazenes exhibit higher regioselectivity than those functionalized in organic solvents. This method provides a facile route for the green synthesis of functional polyphosphazenes without organic solvents.
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2014
·Vol. 4
·期 89
·48317-48321
·
IF 3.708
Yun Yu,Weimin Hou,Xuebing Hu,Yang Yu,Le Mi,Lixin Song
A novel superhydrophobic Al2O3 microfiltration membrane was prepared by the layer-by-layer assembly of TiO2 coating with subsequent fluorination grafting surface treatment by 1H,1H,2H,2H-perfluorodecyltriethoxysilane. The influence of surface morphology on membrane superhydrophobicity, pore size diameter distributions and pure water permeability of the different membranes were studied. By optimizing the grafting parameters, a needle-like surface of grafted TiO2-coated Al2O3 membrane with a water contact angle of 169.5° was obtained. The pure water permeability of different membranes varied from 100 l m−2 h−1 bar−1 before grafting to 3–5 l m−2 h−1 bar−1 after grafting, and the grafted superhydrophobic membrane showed excellent water repellence. The novel superhydrophobic membrane is shown to be promising for liquid–liquid and gas–liquid separation.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）