SEPARATION AND PURIFICATION TECHNOLOGY
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2021
·
IF 7.312
Temitope Fausat Ajibade,Huali Tian,Kayode Hassan Lasisi,Qiang Xue,Weihao Yao,Kaisong Zhang
Despite advances in membrane technology, the separation of complex oily wastewater using membrane filtration remains a daunting challenge for the industry. Recent approaches including membrane modification with two-dimensional (2D) nanosheets, showed susceptibility to swelling, fouling, and instability during operation. As a game-changer approach, a polyacrylonitrile (PAN) UF membrane modified with 3D nanostructured composite of MXene and O-MWCNT was introduced for the first time to treat complex oily wastewater. The composite membrane showed high separation performance of soluble dye-oil-water emulsion while maintaining high water permeability. Moreover, during the operational period, the composite membrane exhibits excellent antifouling and anti-swelling properties due to the synergetic effects conferred by the 3D nanostructures. Furthermore, the composite membrane possesses remarkable chemical stability evidenced by its high corrosion resistance when exposed to a strong acid (3 M HCl) and oxidant (NaOCl) solution for a long-time period. Overall, the operational stability was maintained in terms of flux and high rejection of oil and dye over a 45 h long-term operation. Consequently, this work provides an innovative, stable, and highly facile process for fabricating scalable UF composite membrane for the treatment of complex oily wastewater in a harsh chemical environment.
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CHEMICAL ENGINEERING JOURNAL
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2025
·
IF 13.2
Zhihui Ma,Hongrui Guo,Pengfei Wang,Lichun Dai,Sihui Zhan,Feng Shen
The electrocatalytic oxidation of biomass-derived glucose to formic acid (FA) represents a sustainable route for biomass valorization, yet achieving simultaneous high selectivity and current density remains challenging due to sluggish electron transfer and competing side reactions. Herein, bimetallic oxide ultra-thin nanosheets grown on Ni foam (NiCoO-NS/NF) with established Ni-O-Co electronic channels are fabricated via a facile Cl − corrosion and calcination strategy. The ultra-thin nanosheet structure offers abundant exposed active sites, and the introduced Co 2+ with the unique valence electronic configuration is able to drive the partial electron migration from Ni to Co via the bridging μ-O ligand, forming Ni-O-Co electronic channels. This significantly facilitates electron transport and promotes rapid NiOOH active species formation, as evidenced by in situ spectroscopy measurements and computational analyses. Remarkably, NiCoO-NS/NF exhibits an exceptional GOR current density of 222.70 mA/cm 2 at 1.4 V vs RHE, surpassing NiO-NS/NF and bare Ni foam by 2.29-fold and 7.53-fold, respectively. The enhanced kinetics suppress non-Faradaic degradation, delivering a high Faradaic efficiency beyond 90.00 % within 1 h in 0.1 M glucose. This work provides a novel strategy for constructing electron-channel-rich nanostructures to effectively enhance the performance of glucose electrooxidation over Ni-based catalysts, advancing the development of biomass upgrading.
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Small
·
2025
·
IF 12.1
Lijuan Liu,Yingqiu Zheng,Wenshu Chen,Yongping Du,Linfeng Hu,Guoqiang Luo,Qiang Shen,Jian Zhang
Alkaline water electrolysis holds potential for large-scale, high-purity hydrogen production. However, the slow kinetics of water dissociation and challenging conditions in alkaline environments complicate the search for an electrocatalyst with both high activity and durability. In this study, a highly active and stable amorphous electrocatalyst is introduced, 3Ni─Co─S─O, developed via a straightforward electrodeposition method for alkaline hydrogen evolution reaction (HER). Notably, the surface of the 3Ni─Co─S─O catalyst undergoes a compositional reconstruction during alkaline HER, yet maintains its amorphous structure. This reconstruction spans roughly 6 µm, leading to a gradual decrease in Ni and S content and a corresponding increase in O concentration toward the surface, thereby forming a stable, gradient active layer. Benefitting from this layer and its amorphous nature, the 3Ni─Co─S─O catalyst demonstrates superior alkaline HER activity—requiring only 170 mV to achieve an industrial HER current density of 1000 mA cm −2 . It also showcases remarkable stability, with a mere 15 mV increase in overpotential during continuous HER at 300 mA cm −2 for 24 h, outperforming the commercial Pt/C catalyst. The research provides a novel approach to designing high-performance amorphous alkaline HER electrocatalysts cost-effectively and contributes insights for understanding and developing advanced amorphous catalysts across various applications.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2023
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IF 6.1
Xiang Ye,Wen Chen,Fu-Jie Yan,Xiao-Dong Zheng,Peng-Cheng Tu,Peng-Fei Shan
Berries and their functional components have been put forward as an alternative to pharmacological treatments of type 2 diabetes mellitus (T2DM), and more attention has been paid to the gut microbiome in the pathophysiology of T2DM. Thus, we tried to examine the metabolic impact of red bayberry-derived cyanidin-3-O-glucoside (C3G) and investigate whether the antidiabetic effects of C3G were associated with the gut microbiome. As a result, C3G administration was found to reduce blood glucose levels of diabetic db/db mice, accompanied by increased levels of glucagon-like peptide (GLP-1) and insulin. Moreover, 16S rRNA analysis showed that the dominant microbiota modulated by C3G were pivotal in the glucose metabolism. Furthermore, the modulation of C3G on metabolic activities of gut bacteria leads to an increase in intestinal levels of key metabolites, particularly short-chain fatty acids. This contribution helps in promoting the secretion of GLP-1, which in turn increases insulin release with the purpose of reducing blood glucose levels. Overall, these findings may offer new thoughts concerning C3G against metabolic disorders in T2DM.
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高影响因子
FUEL
·
2019
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IF 5.128
Xiaodong Li,Yanli Huang,Qian Zhang,Zhijun Zuo,Xiaodong Wang,Vladimir A. Vinokurov,Zheng Wang,Wei Huang
Ni-MoCeZr-MgAl(O) mixed oxide catalysts were successfully prepared from the Ce, Zr and Mo promoted hydrotalcite-like compounds (HTLcs) precursors using the simple and effective hexamethylenetetramine(HMT)-assisted hydrothermal synthesis method by tuning the molar ratio of n(HMT)/n(NO 3 − ). The influence of Ni content (3, 4.8, 6, 9 and 12%) on the catalytic performance of these catalysts in dry reforming of methane (DRM) was focused. Adjusting the content of Ni was able to change the metal dispersion and metal particle size, and small-sized (around 7 nm) and evenly dispersed Ni particles were obtained at Ni content of 6%. The catalyst with 6% Ni loading stood out for the high activity and stability, the CH 4 conversion of which fluctuated around 95% continuously for 610 h under GHSV of 60,000 mL·g cat −1 ·h −1 , and it was still above 92.8% throughout the 36-h-duration DRM experiments under GHSV of 80,000 mL·g cat −1 ·h −1 . This research may provide a simple and effective methodology for the synthesis of stable and efficient DRM catalysts.
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Sustainable Energy & Fuels
·
2022
·Vol. 6
·期 11
·2745-2754
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IF 6.813
Hua Tan,Xuecheng Li,Hao Ma,Xiaolin Yang,Tong Zhan,Wenyu Xie,Suhua Wang,Jiaping Zhu
Herein, N-doped carbon embedded Ni catalysts were prepared by a co-impregnation method followed by pyrolysis in a N2 atmosphere for transfer hydrogenolysis of lignin β-O-4 alcohol and ketone model compounds using isopropanol as the hydrogen source. It was found that pyrolysis at 800 °C resulted in the formation of graphitic N-doped carbon shell encapsulated Ni nanoparticles (Ni@NC-800). The obtained Ni@NC-800 exhibited higher activity and selectivity to aromatics in the conversion of 2-phenoxy-1-phenylthanol and 2-phenoxyacetophenone, compared with Ni@NC-600 and Ni/NC-800. Moreover, the selectivity to aromatics could be further improved over Ni@NC-800-H, which is Ni@NC-800 after strong acid leaching. However, the presence of Cα–OH in lignin β-O-4 model compounds was essential for their product distributions. The control and characterization experiments suggested that the catalytic reaction occurred on the surface of N-doped carbon shells, because the encapsulated Ni NPs could donate electrons to the outer shells, leading to surface electron enrichment, thus making inert shells the new active sites in Ni@NC-800-H. In addition, Ni@NC-800-H was efficient for the conversion of various lignin β-O-4 alcohol and ketone model compounds with methoxyl groups with high yields of the aromatic products and also possessed high stability during consecutive reaction runs, which is because Ni nanoparticles are physically isolated from the reactive environment.
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BIOMATERIALS
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2012
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IF 7.404
Meirong Huo,Aifeng Zou,Chengli Yao,Yong Zhang,Jianping Zhou,Jing Wang,Qinnv Zhu,Jing Li,Qiang Zhang
In this study, a ligand-PEG-lipid conjugate , octreotide-polyethene glycol-deoxycholic acid (OCT(Phe)-PEG-DOCA, or OPD) was successfully synthesized and used as a targeting molecule for N-deoxycholic acid-O, N-hydroxyethylation chitosan (DAHC) micelles for efficient cancer therapy. DAHC micelles exhibited good loading capacities for doxorubicin (DOX), a model anti-cancer drug, and the modification of OPD showed no significant effect on drug load while slightly increasing the particle size and partly shielding the positive charges on the surface of micelles. Accelerated release rate of DOX from micelles were also observed after OPD modification and the release profile exhibited pH-sensitive properties. Compared with DAHC-DOX micelles, OPD-DAHC-DOX micelles exhibited significantly stronger cytotoxicity to MCF-7 cells (SSTRs overexpression) but with hardly any difference from WI-38 cells (no SSTRs expression). The results of flow cytometry and confocal laser scanning microscopy further revealed that OPD-DAHC-DOX micelles could be selectively taken into tumor cells by SSTRs-mediated endocytosis . In vivo investigation of micelles on nude mice bearing MCF-7 cancer xenografts confirmed that OPD-DAHC micelles possessed much higher tumor-targeting capacity than the DAHC control and exhibited enhanced anti-tumor efficacy and decreased systemic toxicity. These results suggest that OPD-DAHC micelles might be a promising anti-cancer drug delivery carrier for targeted cancer therapy.
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JOURNAL OF INORGANIC BIOCHEMISTRY
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2021
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IF 4.155
Yueqin Li,Changhao Qian,Yun Li,Yong Yang,Dong Lin,Xiaohui Liu,Chen Chen
Two novel Fe(III) complexes, Fe(HL 1 ) 2 Cl·1.25H 2 O ( 1 ) and Fe(HL 2 ) 2 ·Et 3 NH·H 2 O ( 2 ) (H 2 L 1 = o -vanillin benzoylhydrazone, H 3 L 2 = o -vanillin salicylhydrazone) are prepared. X-ray single crystal diffraction confirms that the hydrazone ligands can be chelated to iron centre resulting in a six-coordinate octahedral configuration. Both complexes show major intercalation effect to the herring sperm deoxyribonucleic acid (HS-DNA) with high binding constants of 2.01 × 10 4 M −1 and 2.24 × 10 4 M −1 , respectively. Molecular docking studies reveal both complexes can intercalate at the gap of DC5-DG2 and DG6-DC1 base pairs of DNA hexamer (1Z3F). The interaction of the complex 1 with plasmid pBR322 DNA induces distinguishable alterations of the DNA morphology. Further, the structure of plasmid pBR322 DNA treated with complex 1 in the presence of ascorbic acid has been damaged probably due to the reactive oxygen species (ROS) generation. What's more, both complexes show high affinity with bovine serum albumin (BSA), the binding constants measured by fluorescence techniques are 5.75 × 10 6 M −1 and 4.39 × 10 7 M −1 , respectively. Molecular docking demonstrates that the complexes prefer the binding pocket of site III (subdomain IIB) of BSA (PDB ID: 4F5S ). Similarly, dynamic light scattering (DLS) reveals that the complexes not only bind to BSA but also induce bigger size aggregates as the concentration increases.
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Food & Function
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2025
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IF 5.4
Yi-Long Ma,Zhi Li,Qian-Lan Wu,Jing Li,Xin Guo,Tian-Le Mao,Kiran Thakur,Zhao-Jun Wei
3,5-O-Dicaffeoylquinic acid (3,5-DCQA) from edible Gongju chrysanthemum has shown protective effects against alcoholic hepatocyte injury in our previous study. However, the specific effects and mechanisms of 3,5-DCQA in a mouse model of liver injury remain underexplored. This study aimed to examine the efficacy and primary mechanism of 3,5-DCQA from Gongju chrysanthemum in ameliorating acute alcoholic liver injury in mice. The results indicated that 3,5-DCQA effectively attenuated inflammation and apoptosis by regulating the content of key factors (e.g. MyD88, NF-κB) in the TLR-4/NF-κB pathway, contributing to its protective role against alcohol-induced liver injury. 3,5-DCQA also inhibited inflammation and apoptosis by recovering the key metabolites (e.g. phosphatidylserine) and related genes (e.g. Lpgat1) of glycerophospholipid metabolism. These results were further verified by transcriptomic and metabolomic analyses, showing that 3,5-DCQA exerts protective effects against alcohol-induced liver injury by modulating glycerophospholipid metabolism and suppressing oxidative stress, inflammation, and apoptosis through the TLR-4/NF-κB pathway. The current findings highlight the hepatoprotectivity of 3,5-DCQA and may facilitate the application of Gongju chrysanthemum in liver-protective functional foods.
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高影响因子
JOURNAL OF CHEMICAL RESEARCH
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2020
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IF 0.593
Zhenzhen Geng,Hong-yu Zhang,Guohui Yin,Yuecheng Zhang,Jiquan Zhao
The ionic liquid 1-methyl-3-(3-sulfopropyl)imidazolium chloride ([MIMPs]+Cl-) in combination with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and sodium nitrite (NaNO2) as a catalytic system demonstrates high efficiency in the one-pot two-step aerobic oxidative condensation of benzyl alcohols with 1,2-phenylenediamines to give benzimidazoles. Various benzimidazoles are obtained in good to excellent yields by this strategy.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2016
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IF 3.138
Shicheng Lei,Minhao Xie,Bing Hu,Li Zhou,Yi Sun,Muhammad Saeeduddin,Hongcheng Zhang,Xiaoxiong Zeng
In the present study, pear polyphenol oxidase (PPO) was purified, immobilized and applied for the synthesis of theaflavin-3,3′-digallate (TF3). Firstly, PPO of pear ( Pyrus bretschneideri Rehd cv. Huangguan) was purified 24.36-fold in specific activity with a recovery of 6.77% by sequential use of precipitation with 70% saturated ammonium sulfate and chromatography of DEAE-Sepharose Fast Flow column. The purified pear PPO, found to be a dimer of identical subunits of molecular mass 35 kDa, was then successfully immobilized onto Fe 3 O 4 /chitosan nanoparticles via glutaraldehyde coupling reaction. Finally, TF3 was effectively synthesized by applying the immobilized PPO as biocatalyst with epicatechin gallate (ECG) and epigallocatechin-3- O -gallate (EGCG) as substrates, and the maximum yield of TF3 was 42.23% based on the amount of ECG added. In addition, the immobilized enzyme still remained 85% of its initial ability after successive usage of 8 cycles and could be stored for 30 days with less loss of activity. All the results suggest that the developed procedure is quite useful and has great potential for synthesis of TF3 and other theaflavins.
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PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2020
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IF 8.758
Qianyu Zhao,Hua Zhang,Haitian Zhao,Jia Liu,Jingyi Liu,Zilong Chen,Bin Li,Xiaojun Liao,Joe Mac Regenstein,Jing Wang,Xin Yang
Seven magnetic covalent organic framework molecularly imprinted polymers with magnetic responsiveness, large specific surface area, and molecular recognition ability were successfully synthesized, suitable for the separation of cyanidin-3-O-glucoside from complex samples. Using a room-temperature synthesis strategy, covalent organic frameworks accompanied by imprinted sites were formed in one step on the functionalized magnetic nanoparticles with 1,6-hexanediamine. The composite materials were easy to prepare and showed high adsorption capacity (127 mg g–1) together with favorable adsorption selectivity for cyanidin-3-O-glucoside over other flavonoids and phenolic acids. Magnetic covalent organic framework molecularly imprinted polymers exhibited good stability in 10 adsorption–desorption cycles. This work established a new method of extracting and separating high-purity anthocyanins and even unstable natural compounds.
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危险品化学品经营许可证（带存储）