RSC Advances
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2026
·Vol. 16
·期 21
·18938-18951
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IF 6.1
Ming Xu,Xihang Wang,Ziyi Zhou,Linna Wang,Jia Zhou,Xinyue Hu,Yuanfei Wang,Tong Wu
Hypertrophic scarring is characterized by excessive dermal fibrosis and irregular collagen metabolism, mediated by fibroblasts derived from keloids. This condition typically arises from improper wound healing after deep burns, trauma, or surgical procedures. Although intralesional injections of botulinum toxin type A and 5-fluorouracil are common clinical treatments, their effectiveness is often limited by temporary drug retention, insufficient penetration depth, and complications from repeated injections. To overcome these challenges, we developed an injectable composite hydrogel system, F@P-B-SilMA, to promote scarless wound healing. Systematic characterization revealed that this system undergoes rapid UV-initiated in situ polymerization and exhibits a three-dimensional porous microstructure. It also demonstrates excellent tissue adhesion and mechanical compliance, along with favorable rheological properties, and tunable degradation kinetics that align with the various phases of wound healing. These attributes collectively meet the essential criteria for advanced wound dressings. Comprehensive in vitro and in vivo evaluations confirmed the system's biocompatibility and its dual ability to accelerate wound closure while suppressing fibrotic proliferation. The injectable F@P-B-SilMA composite hydrogel system represents a promising therapeutic approach for clinical scar management, showcasing significant potential as a next-generation wound dressing for scarless tissue regeneration.
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高影响因子
ACS Applied Materials & Interfaces
·
2025
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IF 8.2
Yuehan Zhang,Panpan Zhao,Zhixuan Yu,Jianguo Zhao,Junfeng Zhai,Shaojun Dong
The efficient conversion of renewable biomass into value-added products is essential for sustainable development. In this work, we report a two-chamber photocatalytic fuel cell (PFC) consisting of a NiFe-LDH/BiVO4/FTO photoanode and a BOD/TCPP/BP/ITO biocathode, which allows for the simultaneous accomplishment of energy conversion and bias-free production of 2,5-furandicarboxylic acid (FDCA). After optimization, the PFC achieves a maximum power density of 859.0 ± 3.0 μW cm–2 at 0.52 V. TEMPO-mediated 5-hydroxymethylfurfural (HMF) oxidation occurs spontaneously within the PFC upon illumination due to the potential difference between the photoanode and biocathode, effectively and selectively converting HMF to FDCA with a yield (%) and Faradaic efficiency of approximately 100%, and possesses good durability after six cycles (30 h) of FDCA production (retaining 90.8% of its initial value). Therefore, the proposed PFC offers a promising solution to the challenges associated with the conversion of renewable biomass.
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INORGANIC CHEMISTRY
·
2025
·
IF 4.7
Yidan Ouyang,Yongxuan Wang,Jingjing Kou,Junhui Cai,Ruijie Jin,Zehong Chen,Ruilan Xu,Zhengbao Wang,Yong Peng
Efficient adsorptive removal of dyes from aqueous solutions by solid porous materials depends on the number of adsorption sites and rapid mass transfer in the pore channel networks. In this work, alkaline coetching on conventional bulky ZSM-5 zeolite by tetrapropylammonium hydroxide and sodium metaaluminate was developed to produce hierarchical ZSM-5 zeolites with a hollow structure. The synergistic etching effect was systematically investigated by adjusting the etchant amount and etching conditions. The dissolution-protection reconciled etching mechanism was demonstrated, and a map illustrating the synergistic relationship was proposed. The etched zeolite exhibited a hierarchical pore structure with a high mesopore volume of 0.68 cm3 g–1 and a large pore size centered around 30 nm, which are beneficial for the mass transfer of large dye molecules. Besides, it had more silanol groups and a lower Si/Al ratio (11–15) with evenly distributed Al element, thus significantly increasing the active adsorption sites. The hierarchical hollow ZSM-5 zeolites presented a great adsorption capacity of 120.95 mg g–1 for methylene blue at a pH of 12 and a high rhodamine B uptake (23.84 mg g–1 under specified conditions). The synergistic etching method is expected to finely manipulate the microstructure of zeolite materials, which would expand their applications in many fields, such as adsorption and catalysis.
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Translational Pediatrics
·
2025
·Vol. 14
·期 6
·1213
·
IF 1.7
Zihong Shan,Chenghui He,Qingyao Yang,Jingjing Xiong,Meng Li,Mingyao Meng,Yongkun Huang
Background Previous research has indicated that chenodeoxycholic acid (CDCA) plays a significant role in intestinal motility and is implicated in some gastrointestinal (GI) disorders. However, the impact of CDCA on defecation patterns in infants, particularly those who are breastfed, remains unclear. This study explored the relationship between CDCA and defecation frequency in breastfed infants, focusing on the underlying mechanisms. Methods We measured CDCA levels in stool samples of infants with varying defecation frequencies using metabolomics, along with studies to explore the impact of CDCA on murine colonic transit and with in vitro cellular studies to elucidate the underlying physiological mechanisms. Results In our murine model, CDCA treatment increased GI transit distance, enhanced fecal water content, and reduced transit time, without causing significant colonic damage. Additionally, CDCA treatment enhanced 5-hydroxytryptamine (5-HT) secretion and upregulated signaling molecules such as tryptophan hydroxylase 1 (Tph1), G protein-coupled bile acid receptor 1 (TGR5), and transient receptor potential ankyrin 1 (TRPA1). Selective inhibition of these pathways suppressed 5-HT secretion and normalized intestinal motility parameters, confirming their mechanistic role. Moreover, CDCA treatment of rat insulinoma-derived RIN-14B cells also resulted in increased 5-HT secretion. Conclusions These findings reveal that CDCA significantly correlates with defecation frequency in breastfed infants and likely influences intestinal motility through the TGR5/TRPA1-5-HT signaling axis.
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CARBOHYDRATE POLYMERS
·
2026
·
IF 13.2
Jinpeng Zhai,Chao Liu,Lijuan Sun,Beichen Xue,Yongxin Wu,Rui Xiao
Biomass-derived carbohydrates, as abundant and renewable feedstocks, hold great promise for producing porous carbon materials (PCMs) applicable in CO 2 capture and syngas purification. This study presents a novel strategy for synthesizing N, O-dual doped carbon (NOC) materials through co-pyrolysis using 5-hydroxymethylfurfural (5-HMF) and chitosan (CTS) as precursors, wherein 5-HMF acts as a structural modulator. Combining experimental characterization with density functional theory (DFT) calculations, this work systematically investigated the synergistic mechanism between functional group evolution and carbon framework construction during co-pyrolysis, and elucidated the influence of N, O doping configurations on CO 2 adsorption selectivity. The results indicate that the incorporation of 5-HMF promotes a three-step reaction pathway introducing N, O-containing functional groups such as imine group (C=N) and carbonyl (C=O). The NOC prepared at 800 °C exhibited a CO 2 /H 2 selectivity of 43.4 and a CO 2 /(CO + H 2 ) multicomponent selectivity of 24.4 in a continuous flow (CO 2 /CO/H 2 , 25 °C, 1 bar). Theoretical calculations further revealed that the synergistic coupling of pyridinic N and carbonyl groups on the carbon surface significantly enhances surface polarity and Lewis basicity, thereby strengthening the selective adsorption of polar CO 2 molecules via Lewis acid-base interactions and electrostatic induction.
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CATALYSIS LETTERS
·
2026
·Vol. 156
·期 3
·80
·
IF 2.5
Li Xincheng,Huang Pengpeng,Fan Mingming,Zhang Pingbo
Isostearic acid, a bio-based and environmentally friendly chemical, has attracted considerable attention because of its high value as an oleic acid derivative. The synthesis of isostearic acid via oleic acid isomerization over commercial H-ZSM-5 zeolites is limited by low yield and acid value, mainly due to diffusion constraints. To address this issue, a hierarchical-pore H-ZSM-5 zeolite (Meso-5) was synthesized using Silicalite-1(S-1) as a seed crystal to enhance diffusion and catalytic performance. The catalyst was comprehensively characterized by XRD, SEM, BET, TGA, FT-IR, and Py-FTIR. Meso-5 efficiently catalyzed the isomerization of oleic acid, attributed to its abundant Brønsted and Lewis acid sites whose synergistic interaction significantly promoted the formation of branched-chain products. The catalyst delivered a selectivity of 87.3% with a 71.1% yield in the first run, and even after five reuse cycles it maintained 82.1% selectivity with a 55.6% yield. Evidently, the hierarchical pore structure of the catalyst significantly facilitated the diffusion of oleic acid molecules and their isomerized intermediates, thereby enhancing the overall catalytic activity. The resulting isostearic acid was purified via a simple recrystallization procedure to a purity of 83.4% and an acid value of 186.7 mg KOH/g, both meeting the standards of commercial isostearic acid. These findings provide a robust basis for further catalyst optimization and scale-up toward industrial isostearic acid production. Graphical A tandem catalytic route combining ZSM-5-driven isomerization with Ni/C-catalyzed hydrogenation enabled the efficient conversion of oleic acid to isostearic acid. The hierarchical H-ZSM-5 structure enhanced branched-chain formation, ensuring high selectivity and yield toward the desired product
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MOLECULES
·
2024
·Vol. 29
·期 4
·850
·
IF 4.2
Meng Guo,Dou Wu,Hongyu Yang,Xiao Zhang,Dong-Xu Xue,Weiqiang Zhang
The use of gaseous CO in Pd-catalyzed carbonylative quinolone synthesis presents challenges related to safety and precise pressure control. In response, a streamlined non-gaseous synthesis of 4-quinolone compounds has been developed. This study introduces a tunable CO-releasing system utilizing Fe(CO)5activated by a dual-base system of piperazine and triethylamine. This alternative liquid CO resource facilitates the palladium-catalyzed carbonylative C-C coupling and subsequent intramolecular cyclization. By tuning the tandem kinetics of carbonylation and cyclization, this non-gaseous method achieves the successful synthesis of 22 distinct 4-quinolones with excellent yields. This is achieved through the three-component condensation of sub-stoichiometric amounts of Fe(CO)5with 2-iodoaniline and terminal alkynes. Operando mechanistic studies have revealed a novel CO transfer mechanism that facilitates homogeneous carbonylative cyclization, distinguishing this method from traditional techniques. In addition to addressing safety concerns, this approach also provides precise control over selectivity, with significant implications for pharmaceutical research and the efficient synthesis of pharmaceutical and bioactive compounds.
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FUEL PROCESSING TECHNOLOGY
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2012
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IF 2.945
Chao Duan,Xin Zhang,Rui Zhou,Yuan Hua,Li Zhang,Jie Chen
HZSM-5/SAPO-34 catalysts were prepared by physical mixture (named as ZS(m)-MM-n) and hydrothermal synthesis (named as ZS(m)-HS-n), respectively. Ethanol to propylene over these as-prepared catalysts was investigated under different reaction conditions. In addition, the physicochemical properties of these catalysts were characterized by AAS , XRD , N2 isothermal adsorption–desorption, SEM , NH3-TPD and TPO . The catalytic reactivity of HZSM-5/SAPO-34 catalyst was strongly dependent on its preparation method and composition as well as the reaction conditions. ZS(25)-MM-4 (HZSM-5/SAPO-34 = 4, weight ratio; HZSM-5 with Si/Al2 = 25 molar ratio) in isothermal fixed-bed reactor showed the highest propylene yield of ca. 34.5% among these catalysts and the poor catalytic stability. The use of nonisothermal fixed-bed reactor with the temperature configuration (2) significantly improved the catalytic stability of ZS(25)-MM-4. Synergetic effect of HZSM-5 with SAPO-34 occurred in HZSM-5/SAPO-34 catalyst, which modified its properties and catalytic reactivity. The concentration and the strength distribution of acid sites were closely relative to the catalytic reactivity of HZSM-5/SAPO-34 catalyst. For achieving the high yield of propylene, it was necessary that HZSM-5/SAPO-34 catalyst had the moderate concentration and strength distribution of acid sites.
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Journal of Energy Chemistry
·
2026
·
IF 15.6
Yanan Chang,Qiao Tan,Qingjun Jiang,Xuexuan Zhong,Xiaoxuan Li,Jianchun Bao,Jie Zhang,Dongdong Xu,Ying Liu
The reactant-adsorption mechanism and reactive oxygen species (ROS) oxidation mechanism represent two vital strategies for boosting the selectivity of the 5-hydroxymethylfurfural oxidation reaction (HMFOR). Still, their compatibility remains challenging and has rarely been reported. Herein, using Pd nanoparticles as the reactant adsorption center and ROS producer, and NiMoO 4 nanorod array as the electrocatalytically active component, a Pd/NiMoO 4 Mott-Schottky heterojunction on Ni-foam skeleton is constructed. The Mott-Schottky structure tailors the Fermi level and energy band structure of Pd/NiMoO 4 , thereby reinforcing its plasmon effect. The prominent plasmon effect increases the carrier density (from 0.6 × 10 27 to 2.4 × 10 27 cm −3 ), lowers the activation energy of HMFOR (from 11.7 to 5.8 kJ mol −1 ), and triggers the formation of ROS ( 1 O 2 and ·O 2 − ) that directly attack HMF, accelerating its conversion to FDCA. Meanwhile, in situ Fourier transform infrared and Raman spectroscopy tests reveal that the decorated Pd nanoparticles not only effectively accelerate the adsorption of HMF and OH − reactants, but also promote the formation of NiOOH active sites. Under the joint effect of these favorable factors, the Pd/NiMoO 4 /NF requires only 1.32 V to afford 50 mA cm −2 under 561 nm illumination, and importantly, achieves a high HMF conversion rate of 99.3%, FDCA selectivity of 98.2%, and Faradaic efficiency of 95.2%, which are superior to those without light irradiation (98.5% HMF conversion rate, 88.7% FDCA selectivity, and 85.0% Faradaic efficiency). When assembled as an HMF-assisted anion exchange membrane HER||HMFOR electrolyzer, a voltage of merely 1.63 V is needed to deliver 500 mA cm −2 , demonstrating its vast production capacity. This multiscale regulation merges the reactant adsorption mechanism with plasmon-induced ROS, enabling the synergistic use of renewable electricity and light energy, and delivering exceptional light-assisted electrocatalytic HMF-to-FDCA performance.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2019
·
IF 3.375
Zhiyong Xu,Wenbo Zhao,Xuhao Xie,Yanhong Li,Yuan Chen
Phase-change absorption has shown a promising application prospect for acid gas capture because only the gas-rich phase needs to be transported to the stripper for recovery, which could drastically reduce the energy consumption of the regeneration process. In this study, the liquid–liquid phase-change behavior of a new recyclable ternary system, composed of 1,5-diazabicyclo[4.3.0]non-5-ene (DBN)/hexadecane/hexanol, was evaluated for capturing H2S. The absorption adduct was the [DBNH]+[SH]− salt, and the cause of the phase change was attributed to the polarity difference between the upper and lower phases. Furthermore, considering that only the lower phase needed to be heated for regeneration, the gravimetric absorption capacity was calculated to be 0.205 g H2S/g lower phase at 1 bar and 293.15 K. To the best of our knowledge, this is the largest gravimetric absorption capacity for H2S capture obtained to date. Additionally, when the absorption reached equilibrium, DBN, hexanol, and H2S were concentrated in the lower phase, while hexadecane mostly remained in the upper phase. The DBN/hexadecane/hexanol system showed that the benign desulfurization efficiency was nearly 100% under the condition that the molar ratio of H2S gas to DBN is not more than 0.6 mol/mol. The cyclic absorption experiments showed that the H2S gas could be easily released by bubbling N2 at 80 °C, which indicated the low energy requirement for the regeneration of the absorbent.
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TOPICS IN CATALYSIS
·
2026
·
IF 3.7
Mu Yifang,Li Yanhong,Huang Aisheng
Direct synthesis of dimethyl ether (DME) from carbon dioxide (CO 2 ) hydrogenation by using bifunctional catalysts has attracted much attention in view of CO 2 conversion and utilization. However, direct CO 2 hydrogenation to DME is challenging due to kinetics and thermodynamic limitations, thus requiring the development of more effective bifunctional catalysts. In this work, metal-organic framework (MOF) Cu/Zn-BTC derived CuZnO catalyst is developed and combined with HZSM-5 for direct CO 2 hydrogenation to DME. The influence of Si/Al ratio of HZSM-5, mass ratio of CuZnO and HZSM-5, reaction temperature, reaction pressure and space velocity on the catalytic performances of the CuZnO/HZSM-5 bifunctional catalysts is systematically examined in a fixed-bed reactor. Attributing to a high activity of the Cu/Zn-BTC derived CuZnO catalyst for CO 2 hydrogenation to methanol, the CuZnO/HZSM-5 bifunctional catalysts display high CO 2 conversion and DME selectivity. Under a mild reaction condition (225 °C and 3.0 MPa), a high CO 2 conversion of 54.3% and DME selectivity of 79.5% are obtained for the bifunctional catalysts, which outperform the state-of-the-art catalysts for CO 2 hydrogenation to DME. Further, after 100 h of reaction, the bifunctional catalyst can still maintain a high CO 2 conversion rate (~ 52.6%) and DME selectivity (~ 77.3%), which suggests promising prospects for industrial applications.
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Journal of the Taiwan Institute of Chemical Engineers
·
2026
·
IF 6.9
Abrar Hussain,Ndumiso Vukile Mdlovu,Kuen-Song Lin,Chi-Jung Chang,Amin Hussain
Background The conversion of CO 2 into value-added fuels and chemicals remains one of the major challenges in catalysis and sustainable energy research. Developing efficient catalysts for CO₂ hydrogenation to methanol and dimethyl ether (DME) is essential for reducing greenhouse gas emissions and promoting carbon recycling. Methods In this work, a Zr-modified CuO–ZnO–Al₂O₃ (CZZA) catalyst was synthesized via a co-precipitation method for CO 2 hydrogenation. The catalyst systems “CZZA/HZSM-5-L” and “CZZA/com-HZSM-5” represent Zr-modified CZZA physically integrated with loofah-templated and commercial HZSM-5 (Si/Al = 25), respectively. A bio-HZSM-5 catalyst was also prepared using loofah sponge and rice husks as dual biotemplates to promote methanol dehydration into DME. The novelty lies in (i) the dual-biomass templating strategy (silica-rich rice husk vs. low-silica loofah) to achieve macro– meso –micro hierarchies while retaining MFI crystallinity, and (ii) Zr-promotion of the Cu–ZnO–Al₂O₃ matrix to enhance Cu⁺/Cu²⁺ and Cu–Zn interfacial sites, enabling efficient one-pass CO₂ → MeOH → DME conversion at 280 °C and 30 bar. Significant findings Zr incorporation significantly improved the structural and electronic properties of the CZZA catalyst, leading to enhanced surface area, active site dispersion, and CuO–ZnO interfacial synergy. Among all tested catalysts, the CZZA/HZSM-5-L bifunctional catalyst achieved the highest DME yield (13.2 %), DME selectivity (58.6 %), and CO₂ conversion (22.5 %) at 280 °C and 30 bar. An economic evaluation of 5- and 10-ton-per-day (TPD) DME production using refinery waste CO₂ showed payback periods of 2.98 and 2.44 years, respectively. Sensitivity analysis (±20 % variation in H 2 and DME prices) confirmed the payback remained below 4 years, demonstrating the technical and economic viability of the developed Power-to-DME process.
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