FOOD CHEMISTRY
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2024
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IF 8.5
Aminu Shehu Abubakar,Bilal Ahmad,Nabi Ahmad,Liangliang Liu,Bin Liu,Yatong Qu,Jikang Chen,Ping Chen,Haohan Zhao,Jia Chen,Kunmei Chen,Gang Gao,Aiguo Zhu
Luobuma tea is made from the leaves of Apocynum hendersonii (Bt) and A. venetum (Ht) and has been used for a very long time in China and Japan as herbal tea. This study isolated water-soluble polysaccharides from the two species` teas. Physicochemical properties, structural properties, in vitro and in vivo antioxidant and immunomodulatory activities were determined for the first time. The results showed that the Bt and Ht polysaccharides with molecular weights of 31.21 and 49.11 kDa, respectively, composed of arabinose, galactose, rhamnose, glucose, xylose, fucose, and mannose. A dose-dependent nitric oxide production and interleukin-6 inhibitory effects were obtained. Also, they suppressed the expression of cyclooxygenase-2, tumor necrosis factor-α and interleukin-6 mRNA in LPS-induced RAW 264.7 macrophages. Likewise, Bt and Ht have significantly reduced edema in the paws of mice after carrageenan injection. These results suggested that the Luobuma teas polysaccharides can be explored as potential antioxidants and anti-inflammatory agents.
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JOURNAL OF HAZARDOUS MATERIALS
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2024
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IF 12.2
Xiaoqing Wang,Shangkun Liu,Shaolei Chen,Xubin He,Wenjing Duan,Siyuan Wang,Junzi Zhao,Liangquan Zhang,Qing Chen,Chunhua Xiong
Given the necessity and urgency in removing organic pollutants such as malachite green (MG) from the environment, it is vital to screen high-capacity adsorbents using artificial neural network (ANN) methods quickly and accurately. In this study, a series of ZIF-67 were synthesized, which adsorption properties for organic pollutants, especially MG, were systematically evaluated and determined as 241.720 mg g −1 (25 ℃, 2 h). The adsorption process was more consistent with pseudo-second-order kinetics and Langmuir adsorption isotherm , which correlation coefficients were 0.995 and 0.997, respectively. The chemisorption mechanism was considered to be π-π stacking interaction between imidazole and aromatic ring. Then, a Python-based neural network model using the Limited-memory BFGS algorithm was constructed by collecting the crucial structural parameters of ZIF-67 and the experimental data of batch adsorption. The model, optimized extensively, outperformed similar Matlab-based ANN with a coefficient of determination of 0.9882 and mean square error of 0.0009 in predicting ZIF-67 adsorption of MG. Furthermore, the model demonstrated a good generalization ability in the predictive training of other organic pollutants. In brief, ANN was successfully separated from the Matlab platform, providing a robust framework for high-precision prediction of organic pollutants and guiding the synthesis of adsorbents.
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POLYMER COMPOSITES
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2024
·
IF 4.8
Wei Jiang,Xueyan Yun,Jiushi Guo,Jian Hu,Lijun Song,Pengju Pan,Tungalag Dong
Incorporating inorganic particles is a common approach to preparing polymeric materials with desirable physical properties and processability. However, this often results in increased brittleness, necessitating methods to improve melt strength and toughness. In this study, in situ polymerization was employed to functionalize silica nanoparticles with the silane coupling agent (3-aminopropyl) triethoxysilane (APTES) as a core. A flexible chain segment, poly(butylene itaconate) (PBI), was then introduced as a “rubbery” intermediate layer, resulting in a core-shell structure of poly(L-lactic-co-butanediol itaconate) nano-silica copolymer films (PLBI SiO 2 ) with both branched and “rubbery” structures. Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR) confirmed the formation of macromolecular chains, with the molecular weight ( M n ) of PLBI increasing from 59,638 to 74,306 g/mol. This significant increase supports the “rubbery” core-shell structure. When 0.5% SiO 2 was added, the T 5% of the film increased by 40°C, significantly improving thermal stability. Additionally, the elongation at break increased to 265.7%, while retaining the original tensile strength. Dynamic rheology experiments further confirmed the generation of branched or “rubbery” core-shell structures, and a doubling of gas barrier properties was observed with increased silica nanoparticles, suggesting potential applications in food packaging or biopharmaceuticals. Highlights Nanocomposites with core-shell structure and improved mechanical properties. Dynamic rheology experiments confirmed the formation of the core-shell structure. Significantly improved gas barrier properties due to core-shell structure.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Li Wan,Yan Li,Hong Wang,Yueping Wang,Lianping Song,Wenjuan Liang
The characteristic flavor of Coffea arabica from Yunnan is largely attributed to the primary processing treatments through affecting the VOCs accumulation. Therefore, a rapid and comprehensive detection technique is needed to accurately recognize VOCs in green coffee beans with different pretreatment methods. Hence, we conducted volatile profiles and identified nine markers of three different primary processed green coffee beans from the major production areas in Yunnan with the combined of HS-SPME-GC–MS and PTR-TOF-MS. The relationships between the chemical composition and the content of VOCs in green coffee beans were elucidated. Among the markers, palmitic acid ( F3 ), linoleic acid ( F6 ), α -ethylidene phenylacetaldehyde ( T4 ), and phytane ( T8 ) contributed to the antioxidant activity of sun-exposed green coffee beans. In conclusion, the analytical technology presented here provided a general tool for an overall and rapid understanding of a detailed volatile profiles of green coffee beans in Yunnan.
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JOURNAL OF STORED PRODUCTS RESEARCH
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2025
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IF 2.8
Jia-Ke Li,Deng-Ju Cai,Hang-Yu Zhao,Yu-Xiang Ma,Xiao-Shuang Cai,Hua-Min Liu,Run-Yang Zhang
Tiger nut is a valuable source of vegetable oil. Storage is a crucial factor that influences the retention of its quality during industrial processing. This study aims to investigate the effects of storage (0–180 days, and 15 °C–35 °C) on lipids in tiger nut. Results indicated that oil yield remained stable (18 %–19 %) throughout the storage period. At higher temperatures (35 °C), the content of phospholipids decreased more significantly. Overall, the levels of endogenous compounds, i.e., phospholipids, tocopherols and total phenols, in the tiger nut slightly declined during storage. The oil extracted from stored tiger nut retained strong physicochemical properties and exhibited high oxidative stability (induction period: 51.04–58.50 h). These findings provide a valuable data foundation for comprehensively understanding the lipid profile of tiger nut and oxidative stability in tiger nut oil.
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JOURNAL OF ETHNOPHARMACOLOGY
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2025
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IF 5.4
Youyun Liu,Junxi Liu,Rui Xu,Yonglei Yuan,Qiwen Sun,Susu Ding,Feifei Wang,Liping Qu
Ethnopharmacological relevance Ludwigia adscendens (L.) Hara ( L. adscendens ) is a Traditional Chinese Medicine (TCM), first mentioned in Sheng Cao Yao Xing Bei Yao ( Essential Guide to Raw Herbal Properties ). It clears heat, removes dampness, detoxifies, and reduces swelling. In TCM, it is prescribed for acne caused by dampness-heat accumulation. It is also used for cold, fever, sore throat, boils, dermatitis, and snake or dog bites. Research shows it has antioxidant, antibacterial, anti-inflammatory, and anti-lipoxygenase effects. However, studies on its impact on sebaceous gland function (a key factor in acne pathogenesis) are still limited. Aim of the study This study aims to investigate the effects of L. adscendens extract (LHE) on sebaceous gland function and its mechanisms. Materials and methods Active compounds in LHE were identified using high-performance liquid chromatography (HPLC). Its effects on lipid synthesis, sebocyte proliferation, and reactive oxygen species (ROS) were assessed in a 5α-dihydrotestosterone (DHT)-induced sebocyte model. Untargeted lipidomics was used to analyse sebum composition and detect LHE-induced changes. Anti-inflammatory and antioxidant activities were evaluated using zebrafish models and biochemical assays. Sebum-regulatory efficacy was measured to assess LHE's impact on sebum production. Results LHE showed strong biological activity by activating the PPARγ/LXRα/SREBP1 pathway, reducing lipid production, inhibiting sebocyte hyperproliferation, and delivering notable antioxidant and anti-inflammatory effects. Lipidomic analysis revealed that LHE effectively altered lipid composition, especially by lowering triglycerides (TG), diacylglycerols (DG), ceramides (Cer), and hexosyl-1-ceramides (Hex1Cer), with major changes observed in medium- and long-chain TG and phosphatidylethanolamine (PE) levels. Efficacy tests confirmed that LHE reduced sebum production and improved skin texture by shrinking pore size. Conclusions LHE improves sebaceous gland function by reducing lipid overproduction and hyperproliferation through the PPARγ/LXRα/SREBP1 pathway. It also enhances the lipid profile by lowering key lipid molecules like TGs and PEs. Moreover, LHE shows anti-inflammatory and antioxidant effects. These findings suggest its therapeutic potential for sebaceous gland-related conditions and reveal new insights into its mechanism in topical use.
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MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Yang Zhou,Yuxin Wei,Runqiu Wang,Yanli Wei,Li Wang
A fluorescent sensing method is presented for the determination of L -Cysteine ( L -Cys) based on sulfur quantum dots (SQDs)/MnO 2 nanosheets (MnO 2 NS) nano system. SQDs was prepared from hydrothermal reaction from sublimed sulfur with β-Cyclodextrin as the surface ligand. SQDs have intense fluorescence which will be quenched in the presence of MnO 2 NS. After the addition of L -Cys, the redox reaction of MnO 2 NS and L -Cys results in the recovery of SQDs fluorescence. Under optimal conditions, the sensing system could achieve a sensitive detection of L -Cys with a wide linearity in the range of 8.0 μM-1.0 mM and a detection of limit as 2.44 μM (3σ/k). This sensing method also shows an excellent specificity and anti-inference, which has a great potential application for the real sample detection. The SQDs-MnO 2 NS served as a promising sensing system for the identification of L -Cys.
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JOURNAL OF NANOPARTICLE RESEARCH
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2024
·Vol. 26
·期 5
·1-14
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IF 2.1
Liu Zhe-Nan,Liu Lv-Cheng,Xue Jin-Peng,Li Shi-Gang,Li Xing
In this work, we employed L-methionine (L-M) as the functionalized reagent of AuNPs for the colorimetric and UV–vis dual-mode detection of As 3+ , Cd 2+ , and Hg 2+ ions with excellent selectivity and anti-interference. After adding the target ions, the functionalized AuNPs can be cross-linked together due to the As 3+ /Cd 2+ /Hg 2+ ions reacting with amino N, carbonyl or hydroxyl O of L-methionine to form the coordination bonds, resulting in the aggregation of functionalized AuNPs and cause the different red-shifts of the SPR absorption peak and color changes of functionalized AuNPs solutions. The LODs of the colorimetric sensor are 10 ppb/13 ppb/4 ppb by naked eyes and 2.35 ppb/1.68 ppb/0.32 ppb by UV–vis spectroscopy with good linear relationships between the absorbance ratios (A 633nm /A 519nm , A 645nm /A 519nm and A 665nm /A 519nm ) and As 3+ , Cd 2+ and Hg 2+ concentrations, which can be successfully applied to sense and detect As 3+ /Cd 2+ /Hg 2+ pollutants in tap water, pond water, well water, and other domestic water sources. Graphical Abstract
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NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Yuanbin Li,Siyuan Chen,shanshan Li,Zhenyuan Wang,Chengyu Wu,Jichuan Zhang,Junzi Dong,Jiaheng Zhang
Bioactive constituents in Camellia sinensis (white tea) provide dermatoprotective benefits, but conventional extraction methods are often inefficient and cumbersome. Research on green extraction techniques for white tea and their effects on skin-related bioactivities remains limited. This study therefore established Natural Deep Eutectic Solvents (NaDESs) as a sustainable extraction platform for white tea bioactives and evaluated the multifunctional skincare properties of the resulting extracts. An optimized L-proline/xylitol NaDES significantly enhanced polyphenol extraction efficiency over traditional solvents. the NaDES-derived extract exhibited superior antioxidant and anti-photoaging effects due to its higher polyphenol content, while also inhibiting advanced glycation end-products (AGEs) formation—demonstrating anti-glycation potential. In conclusion, NaDES represents an advanced plant extraction solvent, and the derived white tea extract shows promise as a multifunctional skincare ingredient (antioxidant, anti-photoaging, anti-glycation) for cosmetic and food applications.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Dai Lu,Xing Tian,Zixuan Fu,Sizhao Yang,Yixing Qiu,Yupei Yang,Bin Li,Wei Wang
Despite extensive research into nanozymes, developing highly active catalysts with broad application potential remains a significant challenge. In this study, we synthesized hollow FeNi Prussian blue analog (H-FeNi PBA) nanocages through a straightforward chemical etching method, using FeNi PBA nanocubes as precursors. The resulting H-FeNi PBA nanocages exhibited enhanced peroxidase-mimetic activity, attributed to their increased specific surface area, pore volume, and Fe 2+ content. Leveraging this activity, we developed a novel colorimetric sensing platform for the detection of mercury ions (Hg 2+ ) and L-cysteine (Cys). The platform operates based on the peroxidase-mimetic activity of H-FeNi PBA nanocages, the inhibitory effect of Cys on this activity, and the restoration of activity through the specific complexation between Cys and Hg 2+ . After optimization, the platform demonstrated wide linear detection ranges (0.1–42 μM for Hg 2+ and 1–64 μM for Cys) and low detection limits (0.035 μM for Hg 2+ and 0.24 μM for Cys). The method was successfully applied to detect Hg 2+ and Cys in real samples, showcasing its potential for environmental monitoring and biomedical applications. This work not only provides a simple strategy for synthesizing highly active nanozymes but also highlights their potential in biosensing and catalysis.
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Foods
·
2025
·Vol. 14
·期 9
·1538
·
IF 5.1
Zepeng Li,Runmin Wang,Xiantai Lai,Wenyi Liao,Runfeng Liao,Zhuohong Wu,Guoyan Zhang,Xianghui Qi
D-tagatose is a functional sweetener with glucose-regulating and prebiotic properties, but its bioproduction from D-galactose faces many limitations, particularly the high production costs. In particular, the current biosynthesis of D-tagatose suffers from thermal instability and the substrate selectivity issues of L-arabinose isomerase (L-AI) required to convert D-galactose into D-tagatose. In this study, recombinantEscherichia coliBW25113/pQE-80L-araAF118M/F279Iexpressing double mutant L-AI was immobilized to enhance its stability and reusability. The optimal conditions for whole-cell catalysis were 60 °C, pH 6.5, 5 mM Mn2+, and 20 h, with a yield of 55.2 g/L of D-tagatose. Immobilization with 3% sodium alginate and 2% CaCl2retained 90% of the production efficiency displayed by free cells. Notably, the immobilized cells exhibited enhanced heat resistance (60–70 °C) and operational stability, retaining 76% activity after five cycles. The D-tagatose production was further increased to 129.43 g/L by increasing the substrate concentration to 250 g/L. Compared to free cells, immobilized cells retained 83.6% of the initial yield up to 10 batches. This study presents a cost-effective and sustainable method for the production of D-tagatose using optimized whole-cell catalysis through immobilization, which paves the way to solve industrial challenges such as thermal instability and low substrate efficiency.
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INORGANIC CHEMISTRY
·
2025
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IF 4.7
Jin Chai,Chunpeng Liu,Hongtian Yang,Yide Han,Yufeng Liu,Ying Zhang,Xia Zhang
The bifunctions of fluorescence activity and peroxidase mimics were well-integrated by a hemin chloride-modified Zr-based metal–organic framework (Hemin@NH2-UiO-66), which can catalyze the oxidation of o-phenylenediamine (OPD) to generate 2,3-diaminophenazine (DAP), presenting typical peroxidase mimic properties. The influence of the introduction of hemin chloride upon the enhanced peroxidase mimic activity was clarified, and the nanozyme catalytic parameters were optimized. Interestingly, the oxidized product of DAP presents strong fluorescence emission at 564 nm; combining it with the intrinsic fluorescence emission of NH2-UiO-66 at 452 nm, a dual-emission system could be built up by the resulting Hemin@NH2-UiO-66 in the presence of definite OPD and H2O2. Moreover, the fluorescence quenching effect (564 nm) was observed by adding l-cysteine (l-Cys); based on that, a straight-line dependence of the fluorescence intensity ratio (I452/I564) upon the concentrations of l-Cys was established. The detection limit was 0.21 μmol, and the analytical selectivity for l-Cys was also demonstrated. The work highlights the idea of combining the intrinsic fluorescence property and nanozyme catalytic activity in a functional MOF, and its special usability is found in the ratiometric fluorescence sensing analyses.
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