JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2025
·
IF 9.7
Junqin Mao,Heng Zheng,Qiuyu Zeng,Guoyu Lv
This study presents a dual-layer artificial dura mater, a hierarchically structured fibrous membrane composed of poly(p-dioxanone) (PPDO) and bioactive glass (BG), fabricated using electrospinning and melt-casting techniques. Designed to address the challenges of dura mater repair, the membrane features a dense outer PPDO layer for mechanical resilience and an electrospun inner layer embedded with BG to enable controlled ion release, promoting tissue regeneration and angiogenesis. We evaluated the fibrous membrane’s surface morphology, mechanical properties, hydrophilicity, and in vitro degradation, demonstrating that increasing BG content enhances hydrophilicity, reduces crystallinity, and modulates degradation kinetics. In vitro assays using L929 fibroblasts and human umbilical vein endothelial cells reveal that the PPDO/BG membrane not only supports cell adhesion and proliferation but also fosters a pro-angiogenic environment through the controlled release of bioactive silicon ions. In vivo implantation in a rat dura mater defect model further validates its therapeutic potential, showing reduced adhesion, improved tissue integration, and enhanced vascularization, with the PBD-3 variant exhibiting superior performance due to its optimized BG composition. The synergistic effects of bioactive ion release, mechanical stability, and biocompatibility establish the PPDO/BG membrane as a highly promising dura mater substitute, offering a bioengineered solution for neurosurgical applications aimed at functional tissue regeneration.
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2025
·
IF 9
Wei Chen,Pengfei Wang,Weike Jia,Huidan Zeng
Silicalite-1 zeolites/polymer composite membranes are among the most reliable materials for the pervaporation separation of m-X from xylene isomers. However, the separation factors of the present silicalite-1 zeolites/polymer composite membrane are low. This work has succeeded in fabricating dense and defect-free silicalite-1/PVA composite membrane for first improving the pervaporation separation performance of m-X/p-X isomers. The silicalite-1/PVA composite membrane was prepared by combining solution scraping and vacuum thermal crosslinking methods with fumaric acid as a crosslinker (denoted as silicalite-1/PVA-V). The silicalite-1/PVA-V composite membrane with a thickness of 15.3 μm, prepared with a fumaric acid/monomeric unit of PVA molar ratio of 0.05 after vacuum thermal crosslinking at 160 ℃ for 2 h, exhibited dense and defect-free structure with extremely low xylene swelling degree, good structural stability and mechanical properties as well as excellent pervaporation separation performance. Compared to the pure PVA membrane, the silicalite-1/PVA-V composite membrane exhibited better selective separation performance of m-X isomer. The temperature, amount of fumaric acid, crosslinking degree and membrane thickness significantly influenced the pervaporation separation performance. The optimum selective separation factor of m-X/p-X isomers and the corresponding total permeate flux were about 9.85 and 59.15 g·m −2 ·h −1 (60 ℃), respectively. The pervaporation experiments of long-time and repetitively prepared membrane demonstrated that the silicalite-1/PVA-V composite membrane had long-term structural stability and reproducibility. To demonstrate scalability, we showed that our strategy could produce large-size silicalite-1/PVA-V composite membrane with an area of 1000 cm 2 , which exhibited m-X separation performance similar to that of small membrane coupons. The present work provided a potentially scalable method for producing high-quality silicalite-1/PVA composite membrane for enhancing the pervaporation separation performance of m-X from xylene isomers.
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高影响因子
POLYMER DEGRADATION AND STABILITY
·
2024
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IF 6.3
Zhenyu Jiang,Zhaobei Chen,Zhonglin Luo,Biaobing Wang
A highly efficient flame retardant TFD was synthesized based on 2-thenaldehyde, furfurylamine and DOPO. When 4 % of TFD is incorporated into EP, EP/TFD-4 exhibits 38.9 % of LOI value and UL-94 V-0 rating. In cone calorimeter test, the peak of heat release rate, total heat release, total smoke production are dropped by 20 %, 9 % and 65 % respectively, and the char residue is increased by 67 % as compared with the pure EP. The P/N/S elements in TFD play important roles both in gas phase and condensed phase. The decomposition of 2-thenaldehyde and furfurylamine moieties produces NH 3 , H 2 S, H 2 O, etc., which partly leak and dilute flammable gases, but majorly participate into structural reorganization in the char layer. The degradation of DOPO group releases phosphorus-containing free radicals and phosphate-like compounds. The former quenches the chain combustion reaction, and the later promotes the formation of a stable carbon layer as a barrier effect. Benefited from the good compatability between TFD and EP, and the fine balance between the increased rigidity and the declined cross-linking density, the EP/TFDs exhibit the strikingly similar transmittance to pure EP in the range of 200–800 nm, and the improved mechanical performance in tensile, flexural, and impact tests.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Ze-Tao Xiao,Yuan Hu,Abbas Mohammadi,Xin Wang
Polycarbonate (PC) is a commonly used engineering plastic, but its poor flame retardancy limits its use. In this study, a DOPO-based flame-retardant (DOPO-TMTA) containing P and Si elements was synthesized via a simple method involving 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) and 2, 4, 6-trivinyl-2, 4, 6-trimethylcyclotrisiloxane (TMTA). The PC/mDOPO-TMTA (m = 4, 6, 8) composites were prepared by melt blending PC with different loadings of DOPO-TMTA. The prepared PC/DOPO-TMTA composites had excellent flame retardancy while maintaining good transparency. The limiting oxygen index (LOI) of PC/8DOPO-TMTA reached 32.5 % and achieved a UL-94 V-0 rating. Moreover, cone calorimetry tests revealed that, compared with those of pure PC, the peak heat release rate (PHRR) and total heat release (THR) of PC/8DOPO-TMTA decreased by 39.0 % and 38.1 %, respectively. Compared with pure PC, PC/mDOPO-TMTA also maintained good mechanical properties, and the tensile and impact strengths were slightly improved. The synergistic flame retardancy of DOPO-TMTA on P/Si elements for the PC matrix was revealed by condensed phase and gas phase product analysis. This work provides a good reference for the preparation of PC composites with high transparency and excellent comprehensive properties.
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高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2015
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IF 2.037
Chunlin Li,Qinbo Wang,Binwei Shen,Zhenhua Xiong,Chuxiong Chen
The mole fraction solubilities of 5,10,15,20-tetraphenylporphyrin (TPP) and 5,10,15,20-tetra(p-chlorophenyl)porphyrin (p-ClTPP) in binary system N,N-dimethylformamide (DMF) + water solvent mixtures were measured at atmospheric pressure by using the static method. The temperature and effects of mole fraction of DMF in the solvent mixtures on solubility were studied. The results show that the solubilities of TPP and p-ClTPP increase with the increasing temperature for a certain solvent composition, and the solubilities show a maximum in pure DMF, then the solubilities decrease when the water was added to the system. The experimental data were correlated with modified Apelblat equation. The solubilities calculated by the model were in good agreement with experimental observations. Thermodynamic parameters such as dissolution enthalpy, isobaric heat capacity and Gibbs energy were obtained from the solubility data by using the Clark–Glew equation together with the modified Apelblat equation. The result demonstrated that the dissolving process of TPP and p-ClTPP in DMF + water solvent mixtures is endothermic and not spontaneous.
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高影响因子
Molecular Catalysis
·
2024
·
IF 3.9
Fangfang Huang,Xinyin Zhang,Yuhong Chang,Wenwen Chen,Haishun Wu,Lei Li,Jianfeng Jia
Semiconductor photocatalytic organic reactions have garnered extensive interest owing to their environmentally friendly and sustainable advantages. Herein, the preparation of Ag 2 S@CdS p-n heterojunction through in-situ ion exchange reaction for photocatalytic benzylamine coupling is reported. Compared with pure CdS, Ag 2 S@CdS exhibited significantly enhanced photocatalytic activity for the oxidative coupling reaction of benzylamine. In particular, Ag 2 S@CdS showed high photocatalytic benzylamine conversion (>99 %) after 90 min under sunlight irradiation. The photocatalytic performance test at different wavelengths shows that the broadening of the light absorption range of Ag 2 S@CdS effectively improves the utilization of visible light. The photoelectric performance test demonstrates that the internal electric field of the p-n heterojunction effectively enhances the efficiency of separating photogenerated carriers. Moreover, Ag 2 S@CdS exhibited excellent compatibility with various benzylamine derivatives. The mechanism of photocatalytic benzylamine oxidation by Ag 2 S@CdS was investigated. This work provides some insights into the design of visible-light photocatalysts for selective organic synthesis.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2016
·
IF 5.31
Xiaoxiang Cheng,Heng Liang,Fangshu Qu,An Ding,Haiqing Chang,Bin Liu,Xiaobin Tang,Daoji Wu,Guibai Li
Mn oxide incorporated membranes were fabricated by incorporation of MnO 2 particles prepared using different methods (C-MnO 2 , M-MnO 2 and S-MnO 2 ) on the surface of ceramic ultrafiltration membranes. Initially, the physicochemical properties of prepared MnO 2 particles were systematically analyzed, and S-MnO 2 exhibited the best dispersibility and smallest particle size. Scanning electron microscopy and atomic force microscopy analyses demonstrated that the morphologies and topographies of the fabricated membranes were significantly affected by the preparation method of MnO 2 particles. Subsequently, sodium alginate was employed to investigate the antifouling properties of the fabricated membranes. Although the incorporation of MnO 2 particles increased membrane intrinsic resistance to varying degrees, M-MnO 2 and S-MnO 2 apparently mitigated both reversible and irreversible fouling in the presence of ozone, whereas C-MnO 2 exerted a minor influence. Further, p -chloronitrobenzene was used to study the activity of fabricated membranes in catalytic ozonation. C-MnO 2 , M-MnO 2 and S-MnO 2 incorporated membranes exhibited enhanced activities with the removal efficiencies of 51.7%, 61.5% and 68.0%, respectively. The results indicated that the preparation method of S-MnO 2 was most appropriate for the preparation of highly dispersive MnO 2 particles to incorporate with ceramic membranes. Results in this study contribute to the fabrication of Mn oxide incorporated membranes with an efficient and convenient way, and provide relevant information on their actual application.
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高影响因子
APPLIED SURFACE SCIENCE
·
2017
·
IF 3.387
Fangwei Pan,Rongjun Qu,Xinhua Jia,Changmei Sun,Hushan Sun,Kai An,Yinglei Mu,Chunnuan Ji,Ping Yin,Ying Zhang
Poly( p -phenylene terephthalamide) (PPTA) coated multi-walled carbon nanotubes (PPTA-MWNTs) showed an enhancement effect on the yield strength and Young’s modulus of PVC composite films, but no improvement in toughness. In this paper, MWNTs were covalently and non-covalently coated by N -epoxypropyl PPTA (PPTA-ECH) to prepare PPTA-ECH-MWNTs-NH 2 -x and PPTA-ECH-MWNTs-x, which were used as additives to reinforce PVC composite films. It was found that the maximum yield strength, Young’s modulus, and toughness of PPTA-ECH-MWNTs-NH 2 -x/PVC composite films increased by 227.84%, 201.56%, and 589.96%, respectively, in comparison to pure PVC, while those of PPTA-ECH-MWNTs-x/PVC composite films increased by 215.08%, 153.13%, and 540.81%, respectively. The maximum yield strength, maximum Young’s modulus, and maximum toughness of both PPTA-ECH-MWNTs-NH 2 -x/PVC and PPTA-ECH-MWNTs-x/PVC showed significant improvement as compared to PPTA-MWNTs/PVC composite film and PPTA-MWNTs-NH 2 /PVC. This indicates that N -epoxypropyl PPTA covalently and non-covalently coated MWNTs are promising additives for reinforcing PVC.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2017
·
IF 2.714
Jin Feng,Dongliang Fan,Qiang Wang,Lirong Ma,Wei Wei,Jimin Xie,Jianjun Zhu
The paper addresses the effect of support on the structure and catalytic activity of Ag catalysts supported on SiO 2 , Fe 2 O 3 and Al 2 O 3 xerogel for catalytic reduction of p -nitrophenol. In order to study support effect of Ag catalysts, Ag-based xerogel catalysts (2 wt.%, 5 wt.%) were prepared by a facile two-step approach involving sol-gel method followed by calcination, and several techniques were employed to study the influence of different supports on the catalytic structure and reaction performances. The results showed the selected support is the main factor to determine the porous characteristic, porosities and the catalytic properties of the corresponding catalyst. Moreover, Ag-based xerogel catalysts on different supports were used for the conversion of p -nitrophenol (PNP) to p -aminophenol (PAP). The presence of different oxides as supports played a crucial role in the activity of Ag nanoparticles as reduction catalysts. The results revealed that 5 wt.% Ag based catalysts exhibited better catalytic activity for the reduction of PNP to PAP with sodium borohydride at room temperature. The reduction reaction followed the pseudo first-order kinetics. The order of rate constants of the 5 wt.% catalysts was Ag-Al 2 O 3 < Ag-SiO 2 < Ag-Fe 2 O 3 . It was found that these types of Ag-based xerogel catalysts can be used repetitively up to five times with no significant activity loss in the initial reduction rate.
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高影响因子
RSC Advances
·
2016
·Vol. 6
·期 33
·27542-27556
·
IF 3.289
Chenfeng Xu,Yu Ding,Jiang Ni,Lifang Yin,Jianping Zhou,Jing Yao
Docetaxel (DTX) has profound effects on several hepatic cancer (HC) cells, but shows unsatisfactory clinical efficacy due to the lack of tumor specificity and p-gp mediated drug efflux. Herein, a novel targeted drug delivery nanosystem based on hyaluronic acid (HA) and quercetin (QU) was designed to improve the in vivo therapeutic efficacy of DTX on HC through HA-CD44 mediated targeting and QU-based p-gp efflux inhibition. DTX-loaded HA–QU polymeric micelles (DTX/HA–QU PMs) displayed a mean particle size of 176.8 ± 3.4 nm with a low polydispersity index (<0.2). The drug loading and entrapment efficiency were 23.6 ± 1.3% and 86.8 ± 1.8%, respectively. Not only did the nanosystem facilitate cellular uptake via HA-CD44 mediated endocytosis, but it also preferentially accumulated at the tumor site via the EPR effect. Moreover, DTX/HA–QU PMs showed prolonged circulation time and high stability in the bloodstream, and achieved AUC0–∞ and t1/2 values that were 3.0-fold and 5.51-fold higher than those of Taxotere®, respectively. In addition, an in vitro cytotoxicity study showed that DTX/HA–QU PMs were 13.6-fold more effective than Taxotere®, judging by the IC50. Importantly, DTX/HA–QU PMs presented the highest antitumor efficacy in a xenograft tumor-bearing mice model and the tumor inhibition ratio was 73.91%. Meanwhile, DTX/HA–QU PMs could down-regulate p-gp expression in tumor cells. These results suggested that the targeting moiety and p-gp efflux inhibitory property help DTX to accumulate at the tumor site and improve its antitumor efficacy in vivo.
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高影响因子
CARBON
·
2016
·
IF 6.198
Juhong Zhan,Huijiao Wang,Xuejun Pan,Jinlin Wang,Gang Yu,Shubo Deng,Jun Huang,Bin Wang,Yujue Wang
This study investigated the regeneration of p -nitrophenol (PNP) saturated activated carbon fiber (ACF) by a novel electro-peroxone (E-peroxone) approach, which aimed to simultaneously regenerate exhausted ACF and mineralize desorbed pollutants by coupling conventional cathodic regeneration with ozonation . PNP-saturated ACF was attached to a carbon-polytetrafluorethylene cathode, which was then applied a current to drive cathodic desorption of pre-loaded PNP and electrochemical generation of H 2 O 2 from O 2 in the sparged ozone generator effluent (O 2 and O 3 gas mixture). The electro-generated H 2 O 2 then reacts with sparged O 3 to yield OH, which can rapidly mineralize the desorbed pollutants (PNP and its derivatives). After 3 h regeneration, the E-peroxone process restored ∼95% of the ACF adsorption capacity , and effectively mineralized the desorbed pollutants. In addition, the E-peroxone regeneration did not considerably modify the structural and chemical properties of ACF. Consequently, the ACF exhibited no evident decline in the adsorption capacity after twelve cycles of PNP adsorption and E-peroxone regeneration. These results indicate that the E-peroxone regeneration can successfully achieve the goal of simultaneous regeneration of saturated ACFs and mineralization of desorbed pollutants, and may thus provide an attractive and viable alternative for the regeneration of organic-saturated ACs.
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高影响因子
Science China-Chemistry
·
2016
·Vol. 59
·期 4
·459-465
·
IF 2.429
Yuan Ye,Deng Sufen,Song Shaokun,Hu Weibo,Dong Lijie
In this paper, we reported a technique for the surface modification of poly-( p -phenylene terephthamide) (PPTA) powder coated with polydopamine (PDOPA). We used air oxidation to self-polymerize dopamine (DOPA) to ensure that the PPTA powder was coated. Our results indicate that the modified surface of PPTA powder enhances compatibility with the polymer matrix without damaging its structure. Additionally, it is possible to control the coating thickness of PDOPA by regulating the reaction time. The modified PPTA powder improved the comprehensive property of ethylene-propylene-diene-terpolymer grafted maleic anhydride (EPDM- g -MAH), and it proved that this method can enhance the strength and electric insulativity of EPDM- g -MAH.
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高影响因子
危险品化学品经营许可证（带存储）