Nano-Micro Letters
·
2024
·Vol. 17
·期 1
·1-16
·
IF 31.6
Huang Zekun,Peng Yutao,Zhao Jing,Zhang Shengliang,Qi Penglu,Qu Xianlin,Yan Fuqiang,Ding Bing,Xuan Yimin,Zhang Xiaogang
A flexible dual-band electrochromic device with a high optical modulation and a long cycle life was reported.
The device assembled can modulate the visible light and near-infrared independently and effectively, showing higher energy-saving performance than commercial low-emissivity glass in most climatic zones around the world.
The flexible device also shows good energy storage and energy recycling performances, recycling 51.4% of the energy consumed in the coloration process for local reusing.
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Metals
·
2024
·Vol. 14
·期 8
·922
·
IF 2.6
Wei Guo,Buxiang Wang,Qing Shu
Hydrogen (H2) is considered to be the best carbon-free energy carrier that can replace fossil fuels because of its high energy density and the advantages of not producing greenhouse gases and air pollutants. As a green and sustainable method for hydrogen production, the electrochemical hydrogen evolution reaction (HER) has received widespread attention. Currently, it is a great challenge to prepare economically stable electrocatalysts for the HER using non-precious metals. In this study, a Co/Co3O4/Ti3C2Txcatalyst was synthesized by supporting Co/Co3O4with Ti3C2Tx. The results show that Co/Co3O4/Ti3C2Txhas excellent HER activity and durability in 1 mol L−1KOH, and the overpotential and Tafel slope at 10 mA·cm−2were 87 mV and 61.90 mV dec−1, respectively. The excellent HER activity and stability of Co/Co3O4/Ti3C2Txcan be explained as follows: Ti3C2Txprovides a stable skeleton and a large number of attachment sites for Co/Co3O4, thus exposing more active sites; the unique two-dimensional structure of Ti3C2Txprovides an efficient conductive network for rapid electron transfer between the electrolyte and the catalyst during electrocatalysis; Co3O4makes the Co/Co3O4/Ti3C2Txcatalyst more hydrophilic, which can accelerate the release rate of bubbles; Co/Co3O4can accelerate the adsorption and deionization of H2O to synthesize H2. This study provides a new approach for the design and preparation of low-cost and high-performance HER catalysts.
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Regenerative Biomaterials
·
2024
·
IF 5.6
Sun Yage,Zhao Xinrui,Zhang Qian,Yang Rong,Liu Wenguang
The hypoxia microenvironment post myocardial infarction (MI) critically disturbs cellular metabolism and inflammation response, leading to scarce bioenergy supplying, prolonged inflammatory phase and high risk of cardiac fibrosis during cardiac restoration. Herein, an injectable hydrogel is prepared by Schiff-base reaction between fructose-1,6-bisphosphate (FBP)-grafted carboxymethyl chitosan (CF) and oxidized dextran (OD), following by loading fucoidan-coated baicalin (BA)-encapsulated zein nanoparticles (BFZ NPs), in which immunoregulatory and metabolism improving functions are integrally included. The grafted FBP serves to enhance glycolysis and provide more bioenergy for cardiomyocytes survival under hypoxia microenvironment, and elevating cellular antioxidant capacity via pentose phosphate pathway. OD with intrinsic anti-inflammatory effect can induce M2 polarization of macrophages to accelerate inflammatory elimination. While facing the possibility of endothelial-to-mesenchymal transition (EndoMT) caused by excessive expressed TGF-β1 secreted from M2 macrophages, BFZ NPs can target endothelia cells and intracellularly release BA to regulate the level of fatty acid oxidation, resulting in retained endothelial features and decreased risk of cardiac fibrosis. After being injecting the hydrogel into rats’ infarcted cardiac, the 28 day-post surgical outcomes demonstrate its benign effects on restoring cardiac functions and attenuating adverse left ventricular remodeling. This study shows a promising measure for MI treatment with immunoregulating and metabolism regulation comprehensively.
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Journal of Materials Chemistry B
·
2024
·Vol. 12
·期 14
·3481-3493
·
IF 6.1
Ting Liu,Kangkang Huang,Yuxia Yang,Shengwu Wen,Jingxian Zhang,Suiping Deng,Shaozao Tan,Langhuan Huang
Bacterial infection is the most common risk factor that causes the failure of implantation surgery. Therefore, the development of biocompatible implants with excellent antibacterial properties is of utmost importance. In this study, NIR light-driven AgBiS2@ZIF-8 hybrid photocatalysts for rapid bacteria-killing were prepared. AgBiS2@ZIF-8 exhibited excellent photocatalytic activity due to the rapid transfer of photoelectrons from AgBiS2 to ZIF-8, resulting in abundant reactive oxygen species (ROS) to kill bacteria. Meanwhile, AgBiS2@ZIF-8 exhibited a noteworthy photothermal effect, which could effectively convert NIR light into heat. Subsequently, the NIR light-driven antibacterial activity of AgBiS2@ZIF-8/Ti against S. aureus and E. coli was studied. The experimental results showed that AgBiS2@ZIF-8 displayed enhanced photodynamic therapy (PDT) and photothermal therapy (PTT) performance. Under irradiation with 808 nm NIR light for 10 min, AgBiS2@ZIF-8/Ti could effectively eliminate 98.55% of S. aureus in vitro, 99.34% of E. coli in vitro and 95% S. aureus in vivo. At the same time, AgBiS2@ZIF-8/Ti had good biocompatibility. Therefore, AgBiS2@ZIF-8/Ti showed potential as an antibacterial material, which provided a strategy to fight polymicrobial infections.
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Nature Communications
·
2024
·Vol. 15
·期 1
·1-10
·
IF 14.7
Li Jie,Zhang Fan,Xia Xiaobin,Zhang Kaihang,Wu Jianhui,Liu Yulu,Zhang Chi,Cai Xinyu,Lu Jiaqi,Xu Liangquan,Wan Rui,Hazarika Dinku,Xuan Weipeng,Chen Jinkai,Cao Zhen,Li Yubo,Jin Hao,Dong Shurong,Zhang Shaomin,Ye Zhilu,Yang Minye,Chen Pai-Yen,Luo Jikui
The accurate monitoring of vital physiological parameters, exemplified by heart rate, respiratory rate, and intracranial pressure (ICP), is of paramount importance, particularly for managing severe cranial injuries. Despite the rapid development of implantable ICP sensing systems over the past decades, they still suffer from, for example, wire connection, low sensitivity, poor resolution, and the inability to monitor multiple variables simultaneously. Here, we propose an ultrasensitive multimodal biotelemetric system that amalgamates an iontronic pressure transducer with exceptional point (EP) operation for the monitoring of ICP signals. The proposed system can exhibit extraordinary performance regarding the detection of minuscule ICP fluctuation, demonstrated by the sensitivity of 115.95 kHz/mmHg and the sensing resolution down to 0.003 mmHg. Our system excels not only in the accurate quantification of ICP levels but also in distinguishing respiration and cardiac activities from ICP signals, thereby achieving the multimodal monitoring of ICP, respiratory, and heart rates within a single system. Our work may provide a pragmatic avenue for the real-time wireless monitoring of ICP and thus hold great potential to be extended to the monitoring of other vital physiological indicators.
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Gels
·
2024
·Vol. 10
·期 8
·490
·
IF 5
Minjie Hou,Qi Wang,Shunyu Wang,Zeze Yang,Xuefeng Deng,Hailong Zhao
Cellulose nanofibers (NF) were extracted from kapok fibers using TEMPO oxidation, followed by a combination of mechanical grinding and ultrasonic processing. The TEMPO-mediated oxidation significantly impacted the mechanical disintegration behavior of the kapok fibers, resulting in a high NF yield of 98%. This strategy not only improved the fibrillation efficiency but also reduced overall energy consumption during NF preparation. An ultralight and highly porous NF-based aerogel was successfully prepared using a simple ice-templating technique. It had a low density in the range of 3.5–11.2 mg cm−3, high compressional strength (160 kPa), and excellent thermal insulation performance (0.024 W m−1K−1). After silane modification, the aerogel displayed an ultralow density of 7.9 mg cm−3, good hydrophobicity with a water contact angle of 128°, and excellent mechanical compressibility with a high recovery of 92% at 50% strain. Benefiting from the silene support structure, it showed a high oil absorptive capacity (up to 71.4 g/g for vacuum pump oil) and a remarkable oil recovery efficiency of 93% after being reused for 10 cycles. These results demonstrate that our strategy endows nanocellulose-based aerogels with rapid shape recovery and high liquid absorption capabilities.
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ANALYST
·
2025
·
IF 3.3
Chenyan Li,Yilan Liang,Qincong Feng
Electrochemical biosensors are frequently employed to identify harmful microbes and disease indicators. However, their practical applicability is constrained by poor signal amplification efficiency and immobilization processes on the probe surface. To get over these restrictions, we here integrated roll-cycling amplification (RCA) and CRISPR/Cas12a gene editing tools with electrochemical biosensors. We constructed an electrochemical biosensor based on RCA to activate the cleavage activity of Cas12a. First, by double-stranded nucleic acid aptamer (ds Apt) specifically binding to E. coli-2571, Apt-b was competitively isolated to bind to T4 ligase and produce circular DNA. This in turn activates RCA, which in turn activates the accessory cleavage activity of CRISPR/Cas12a, which in turn cleaves DNA sequences loaded onto the electrode, changing electrochemical signals. With a linear range of 1 × 102–1 × 107 CFU mL−1, a detection limit of 5.28 CFU mL−1, and experimental recoveries of 93.01–101.53%, the measured electrochemical signals were positively connected with the concentration of E. coli-2571 under the optimal experimental conditions. Therefore, by combining two approaches—RCA and CRISPR/Cas12a—our electrochemical biosensor was able to detect E. coli-2571 specifically and sensitively, providing new research opportunities for the detection of other harmful bacteria.
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POLYMERS FOR ADVANCED TECHNOLOGIES
·
2024
·Vol. 35
·期 12
·e70018
·
IF 3.1
Xiaowen Wang,Jun Yan,Yan Yu,Haoyan Qiu,Xuanchuan Li,Paul Joseph,Meiling Zhong,Xinyue Hu,Ri-Chao Zhang
Generally, polymeric materials with superior damping characteristics are in great demand for many advanced functional applications, such as in building, aerospace, electronics, and transport sectors. However, it still remains a challenge to improve the damping characteristics of such materials owing to the lack of adequate practical knowledge in this area. Here, we report on the successful fabrication of silicon rubber (SR)/ferric oxide (Fe 3 O 4 ) composites with excellent damping characteristics. The results obtained from the study showed that the damping characteristics of the specimens increased with the loading of Fe 3 O 4 within a range of −105°C to 200°C. Specifically, the damping factor (tan δ ) is 0.45 at room temperature, and the effective working temperature, the temperatures that correspond to the tan δ > 0.3, ranged from −105°C to 165°C for the loading of Fe 3 O 4 at 60 phr. The scanning electron microscopy results showed that the excellent damping characteristics of composites can be attributed to the good dispersion of Fe 3 O 4 in the SR matrix. This work, therefore, opens up a pathway toward a relatively easy and up-scalable means for fabricating polymer composites that have superior damping characteristics and ones with a wider applicability.
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ACS Biomaterials Science & Engineering
·
2024
·
IF 5.4
Jialuo Chen,Zhipeng Li,Xinpeng Chen,Yurong Sun,Jin Cheng,Aijing Li,Shenzhou Lu,Tieling Xing
Adhesives have garnered significant interest recently due to their application in the field of biomedical applications. Nonetheless, developing adhesives that exhibit robust underwater adhesion and possess antimicrobial properties continues to pose a significant challenge. In this study, motivated by the adhesive mechanism observed in mussels in aquatic environments, dopamine (DA) was added to modify the silk fibroin (SF) solution. Subsequently, tea polyphenol (TP) was incorporated to form a sticky mixture, resulting in a biomimetic adhesive (TP-DA/SF). TP-DA/SF demonstrated rapid, robust, and indiscriminate adhesion to a wide array of substrates and even biological tissues (39 kPa). TP-DA/SF exhibits the ability to replicate the mussel adhesion mechanism of mussels underwater thanks to its biomimetic design. This characteristic provides the material with robust adhesion (40 kPa), notable reusability (at least 10 times), and long-lasting stability, especially in aquatic settings. It is worth noting that TP-DA/SF also demonstrated high adhesion in various water environments, even in solutions with a pH of 7.4 and buffered saline (PBS), which is one of the most widely used buffers in biochemistry research, offering salt-balancing and adjustable pH buffering capabilities. Meanwhile, TP-DA/SF exhibits excellent antibacterial and antioxidant properties due to its tea polyphenol content. After 15 days of wound closure in SD rats, the healing rate in the experimental group reached 93.4%, compared to 83.9% in the control group. Thus, the TP-DA/SF adhesive holds promising potential for biomedical applications, including sutureless wound closure and tissue adhesion.
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Polymers
·
2024
·Vol. 16
·期 8
·1069
·
IF 4.7
Yafeng Huang,Xuan Tian,Jinfei Wang,Kejun Zhong,Yuan Chen,Chenglong Li,Pengxiang Jia
In this research, an ammonium perchlorate/polydopamine (AP/PDA) core–shell composite was prepared in a non-aqueous solution to reduce the mechanical sensitivity of ammonium perchlorate (AP). The result showed that the AP/PDA core–shell composite could be successfully constructed in ethyl acetate solution with an AP recovery rate that reached 86%. The mechanical sensitivity of the obtained AP/PDA core–shell composite was significantly reduced with a PDA content of only 0.76%. The DSC and TG also indicated that the coating of PDA showed catalytic activity in the thermal decomposition of AP with a lower decomposition temperature and a decreased Eavalue of AP. Thus, this study proposed a simple strategy for achieving a good balanced between harnessing the energy and ensuring the safety of ammonium perchlorate by significantly reducing its mechanical sensitivity by using a very low polydopamine coating layer content, and this shows great potential for the design and fabrication of insensitive energetic composites for use in propellants.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2024
·Vol. 333
·期 6
·2709-2722
·
IF 1.5
Wang Guohua,He Shan,Xiao Quanjin,Peng Kun,Tang Donghui,Dong Zhitao,Pan Menglu,Li Shiyou
This study investigates the effects of nitrate exposure on the indigenous consortium mediated remediation of uranium-contaminated groundwater. Intermittent experiments reveal that high-nitrate concentrations hinder uranium reduction, whereas using glycerophosphate as carbon source, microbe could immobilize uranium by generating biomineralized precipitates with high crystallinity, and these precipitates exhibited better stability at high-nitrate concentration compared to those formed at low-nitrate condition. We also elucidated the mechanism of uranium removal by microorganisms under different conditions by analyzing changes in solution chemistry, products formed and microbial community structures. This work extends the scope for treating uranium-contaminated groundwater and is important for achieving long-term treatment of uranium contamination.
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CHEMICO-BIOLOGICAL INTERACTIONS
·
2024
·
IF 4.7
Changfeng Zhong,Changmei Wang,Wei Li,Wenyuan Li,Xuemei Chen,Jieqing Guo,Yifan Feng,Xia Wu
Parkinson's disease (PD) is the fastest growing neurodegenerative disease in the world at present. Neuroinflammation plays an important role in Parkinson's disease. In our study, we initially screened magnolol/honokiol derivatives synthesized by our group for their potential anti-neuroinflammatory properties. This was done using LPS-activated BV-2 microglial cell and MPP + -induced PC-12 cell models. Most of derivatives had increased anti-inflammatory activities and decreased toxicities compared to raw materials. Then, compounds were scored with inflammatory factors IL-1β, TNF-α and IL-6 by molecular docking in silico . Our studies revealed the strongest binding compound HM568 which binds with honokiol and metformin. Furthermore, HM568 showed no acute toxicity in mice through acute toxicity. And it is stable under high temperature, high humidity and strong light irradiation. Combining cell experiments and computer results, HM568 was considered for further in vivo pharmacological validations. Intraperitoneal injection administration of MPTP into C57BL/6 mice was utilized as Parkinson's animal model. Results showed that administration of HM568 for 14 days in MPTP-PD mice led to a significant alleviation in weight loss and movement disorders. Further HM568 could significantly down-regulate the expression levels of inflammatory factors IL-1β, IL-6 and TNF-α in brain tissue of the mouse model, reduce the level of caspase-3 and the ratio of Bcl-2/Bax, and up-regulate the level of transforming factor TGF-β, thus producing anti-apoptosis and anti-neuroinflammatory effects on neuronal cells. In terms of pathological features, HM568 could reduce the infiltration of neuronal cells and alleviate the development of lesions, promote the transformation of microglia from M1 negative phenotype to M2 type, and reverse the reduction of TH-positive immune cells in mouse neurons induced by MPTP. The administration of HM568 could reduce the abnormal accumulation of α-syn, and thus produce neuroprotective effect on MPTP-PD mice. Cell experiments, molecular docking and animal experiments thus depict HM568 as a promising agent to delay neuronal degeneration in PD, and its mechanism is related to anti-neuroinflammation.
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