OPTICAL ENGINEERING
·
2022
·
IF 1.352
Min Zhang,Zhihai Liu,Yiwei Ma,Yu Zhang,Yaxun Zhang,Xinghua Yang,Jianzhong Zhang,Tao Geng,Libo Yuan
We propose a gelatin-coated long period fiber grating humidity sensor which has temperature compensation for low-error humidity detection. The output spectrum shows three resonance dips. The dip caused by gelatin-coated grating has humidity sensitivity of 0.09 nm/%RH and temperature sensitivity of 0.15 nm/°C. Another two dips caused by PDMS-coated grating have almost no response to humidity, which can be used for temperature compensation under low temperature and high temperature range, respectively. We come up with a coefficient matrix and experimentally obtain the humidity and temperature sensitivity of both resonance dips, thus temperature and humidity can be demodulated.
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DOI
高影响因子
JOURNAL OF BIOMEDICAL OPTICS
·
2022
·
IF 3.758
Tongyu Huang,Ruoyu Meng,Jiawei Song,Tongjun Bu,Yuanhuan Zhu,Migao Li,Ran Liao,Hui Ma
Significance: Reflection Mueller matrix imaging is suitable for characterizing the microstructure of bulk specimens and probing dynamic processes in living animals, there are always demands for speed and accuracy for such applications to avoid possible artifacts and reveal a sample’s intrinsic properties.Aim: To demonstrate a design of collinear reflection Mueller matrix fast imaging microscope based on dual division of focal plane (DoFP) polarimeters (DoFPs-CRMMM) which has high measurement speed and accuracy.Approach: In DoFPs-CRMMM, to improve the measurement speed, we applied the dual DoFP polarimeters design on the collinear reflection system for the first time to achieve fast imaging in about 2 s. To improve the measurement accuracy, we improved the double-pass eigenvalue calibration method (dp-ECM) by background light correction, and explored the optimization of the set of reference samples.Results: DoFPs-CRMMM was applied to measure the standard polarization samples and monitor the tissue optical clearing process of an artificial layered bulk tissue. Results show that the system has satisfactory performance which can capture the variation of polarization properties during the dynamic process.Conclusions: We present the establishment and demo application of DoFPs-CRMMM. The measurement speed can be further accelerated for potential applications in monitoring dynamic processes or living biomedical systems.
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DOI
高影响因子
JOURNAL OF BIOMEDICAL OPTICS
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2014
·
IF 2.752
Zijian Deng,Lijia Jing,Ning Wu,Pengyu lv,Xiaoyun Jiang,Qiushi Ren,Changhui Li
By allowing more photons to reach deeper tissue, the optical clearing agent (OCA) has gained increasing attention in various optical imaging modalities. However, commonly used OCAs have high fluidity, limiting their applications in in vivo studies with oblique, uneven, or moving surfaces. In this work, we reported an OCA with high viscosity. We measured the properties of this viscous OCA, and tested its successful performances in the imaging of a living animal’s skin with two optical imaging modalities: photoacoustic microscopy and optical coherence tomography. Our results demonstrated that the viscous OCA has a great potential in the study of different turbid tissues using various optical imaging modalities.
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DOI
高影响因子
OPTICAL ENGINEERING
·
2025
·
IF 1.2
Xianzhen Huang,Yun Ye,Jiaqi Gao,Xingke Zheng
Color conversion layers are extensively utilized in flat panel display technology for their capacity to provide a wide color gamut and improved resolution, along with exceptional design flexibility. The uniformity and thickness of cadmium selenide (CdSe) quantum dot (QD) films are often difficult to control in the preparation of color conversion layers. Interestingly, it is possible to precisely deposit QDs by inkjet printing to improve material utilization. Color conversion layers with optimized spectral properties and light conversion efficiency are successfully prepared by inkjet printing. We employ inkjet printing technology to fabricate CdSe QD color conversion layers with precise control over layer thickness. The effects of layer thickness on spectral properties and light conversion efficiency are systematically investigated. It is found that a layer thickness of 5.5 μm achieves the highest light conversion efficiency at 20.4%, with efficiency decreasing as thickness increases to 6 μm. In addition, it is observed that blue light transmittance decreases from 47.2% to 11.4% with increasing layer thickness, highlighting the importance of thickness control in optimizing spectral properties.
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产品关联
DOI
高影响因子
Neurophotonics
·
2020
·
IF 2.537
Yusha Li,Jianyi Xu,Jingtan Zhu,Tingting Yu,Dan Zhu
Three-dimensional visualization of the innervation in skeletal muscles is helpful for understanding the morphological structure and function. iDISCO, a whole-mount immunolabeling and clearing technique, provides a valuable tool for volume imaging of intramuscular nerve fibers but suffers from the nonspecific staining caused by the anti-mouse secondary antibody when using the murine primary antibody. We developed a modified iDISCO method by introducing pretreatment of ScaleCUBIC-1 reagent, termed m-iDISCO. The m-iDISCO method could eliminate the nonspecific staining and achieve uniform and complete labeling of nerve fibers in various muscles with mouse anti-neurofilament primary antibody. Combining the m-iDISCO method with light-sheet microscopy enabled us to visualize the innervation of adult mouse tibialis anterior and trace the nerve fibers from extramuscular branches to intramuscular terminal branches. This method represents an effective alternative for studying the innervation of intact skeletal muscles in health and disease.
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF BIOMEDICAL OPTICS
·
2015
·
IF 2.859
Lianpeng Zhou,Guoyong Wu,Huajiang Wei,Zhouyi Guo,Hongqin Yang,Yonghong He,Shusen Xie,Ying Liu,Qingan Meng
The objective is to investigate the effects of two different sized (60 and 100 nm) titanium dioxide (TiO2) nanoparticles (NPs) penetration and accumulation in in vitro human normal lung (NL) tissue, lung squamous cell carcinoma (LSCC) tissue, and 650-nm diode laser-pretreated tissue on their optical properties studied with optical coherence tomography monitoring and diffuse reflectance (DR) spectra measurement. As with TiO2 NPs penetrating into the tissues, the intensities of DR of the samples increase, and then the enhancements of DR and the attenuation coefficients of the tissues were quantitatively calculated. The results suggest that 650-nm diode laser pretreatment increased the amounts of TiO2 NPs penetration and accumulation in NL and LSCC tissues, and the tissue optical properties were significantly influenced by accumulation of TiO2 NPs.
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DOI
PubMed
高影响因子
JOURNAL OF BIOMEDICAL OPTICS
·
2017
·
IF 2.53
Qinghua He,Dongmei Li,Yonghong He,Tian Guan,Yilong Zhang,Zhiyuan Shen,Xuejing Chen,Siyu Liu,Bangrong Lu,Yanhong Ji
A laser-induced breakdown spectroscopy and fluorescence spectroscopy-coupled optical system is reported to demodulate digitally encoded suspension array in fluoroimmunoassay. It takes advantage of the plasma emissions of assembled elemental materials to digitally decode the suspension array, providing a more stable and accurate recognition to target biomolecules. By separating the decoding procedure of suspension array and adsorption quantity calculation of biomolecules into two independent channels, the cross talk between decoding and label signals in traditional methods had been successfully avoided, which promoted the accuracy of both processes and realized more sensitive quantitative detection of target biomolecules. We carried a multiplexed detection of several types of anti-IgG to verify the quantitative analysis performance of the system. A limit of detection of 1.48×10−10 M was achieved, demonstrating the detection sensitivity of the optical demodulation system.
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DOI
PubMed
高影响因子
Journal of Nanophotonics
·
2024
·
IF 1.1
YingTe Wang,SiRong Cheng,RongRong Wu,YuanYuan Zhang,BoHan Wang
Nitrogen and sulfur co-doped green fluorescent carbon dots (G-CDs) with quantum yield (QY) of 28.26% were synthesized by hydrothermal method with p-phenylenediamine and thiosemicarbazone as precursors. The synthesized G-CDs exhibit good sensitivity and anti-interference ability for detecting copper ion (Cu2+) by fluorescence quenching (λex=390 nm, λem=535 nm) with a linear range of 20 to 200 μM and the limit of detection of 4.8 μM. This analytical method has been applied to detect Cu2+ of the local lake with good accuracy and recovery.
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高影响因子
JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION
·
2014
·Vol. 30
·期 3
·199-203
·
IF 0.827
Wei-Bin Ma,Jun-Tao Feng,Zhi-Li Jiang,Xing Zhang
We studied the knockdown activity and lethal toxicity of 6 essential oil compounds—methyl salicylate, linalool, 2-phenethyl alcohol, eugenol, β-citronellol, and trans-cinnamaldehyde—as fumigants against adult female Culex pipiens pallens in the laboratory. Of the 6 products tested, trans-cinnamaldehyde was the most toxic (LC50 = 0.26 µl/l air, 24 h) with a slow knockdown time (KT95 = 176.5 min at 0.5 µl/l air). Methyl salicylate displayed a lower toxicity (LC50 = 1.17 µl/l air, 24 h) but the fastest knockdown activity (KT95 = 16.8 min) at the sublethal concentration 0.5 µl/l air. Furthermore, the binary mixture of methyl salicylate and trans-cinnamaldehyde exhibited a combined effect of fast knockdown activity and high toxicity against Cx. p. pallens adults, showing potential for development as natural fumigants for mosquito control.
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DOI
PubMed
高影响因子
OPTICAL ENGINEERING
·
2019
·
IF 1.209
Jianjun Zhou,Jixiang Dai,Shiwen Yang,Yong Wang,Minghong Yang
A fiber-optic carbon monoxide (CO)-sensing system with high sensitivity was proposed by combining Fabry–Perot interferometer (FPI) sensor with sensing material Au/ZnO. The sensitivity is 814 pm / % within the CO concentration range of 0% to 4%. The FPI sensor was fabricated by inserting single-mode fiber into a partially polymer-filled glass capillary to form an air cavity; the length of the air cavity is 76.83 μm. The temperature sensitivity of the FPI is −2.7 nm / ° C, which provides better conditions for measurement of CO. The catalyst Au/ZnO was prepared by coprecipitation, which could catalyze the oxidation of CO at ambient temperature and humidity. X-ray diffraction and scanning electron microscope analysis were employed to reveal the crystalline structure and morphology of the catalyst. To eliminate the influence of ambient temperature change on the accuracy of the concentration test, a fiber Bragg grating with central wavelength of 1550.24 nm was introduced in the experimental setup for the temperature compensation.
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DOI
高影响因子
JOURNAL OF BIOMEDICAL OPTICS
·
2025
·Vol. 30
·期 4
·046501
·
IF 2.9
Huaiyuan Zhang,Yiting Hu,Xingwei Pu,Shizheng Zhang,Yi He,Kun Chen,Ziji Liu
Significance The multiplexing capabilities of fluorescence imaging are enhanced by its exceptional molecular specificity with diverse fluorescent probes, making it a powerful tool for studying complex biological structures, organization, and functions. Recent advances in super-resolution fluorescence microscopy have further revolutionized our ability to explore biology and related fields. However, current multicolor super-resolution fluorescence imaging systems often come with high costs and bulky designs. Aim We present a multicolor extended resolution fluorescence imaging system that uses light-emitting diode to simplify the optical path, make the design more compact, and reduce system costs. Approach This multicolor extended resolution fluorescence imaging system is based on structured illumination, utilizing a simple diffraction unit positioned between the light source and the sample in a wide-field microscope. Notably, this design could be easily integrated into standard widefield microscopes as a convenient add-on unit, enabling extended resolution imaging. Results Our system demonstrates concurrent extended resolved imaging of three-color microsphere beads and successfully showcases multicolor extended resolution fluorescence imaging of biological tissue samples, revealing intricate structural details. Conclusions This system provides a structurally simple, cost-effective alternative to traditional microscopes, offering flexible multicolor extended resolution fluorescence imaging and potential applications in multimodal imaging.
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DOI
PubMed
高影响因子
OPTICAL ENGINEERING
·
2020
·
IF 1.113
Miao Xu,Zi Wang,Hongbo Lu,Longzhen Qiu
A facial method was used to enhance the dynamic response of polyvinyl chloride (PVC) gel tunable lenticular microlens array (LMA). The response time could be reduced using a discontinuous hydrophobic layer-modified electrode substrate due to a decrease in friction between the substrate surface and PVC gel. The application of DC voltage (V = − 45 V) to LMA induced a response time <240 ms. The proposed PVC gel LMA looks promising for use in image processing and two/three-dimensional switchable displays due to its fast-dynamic response, good stability, compact structure, and easy fabrication.
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DOI
高影响因子
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