Frontiers in Materials
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2022
·
IF 3.985
Guo Xin,Wang Jinke,Huang Luyao,Wang Yajie,Ma Li,Zhang Dawei,Ma Lingwei
The corrosion inhibition effect of 3-amino-5-mercapto-1,2,4-triazole (AMT) on AA2024 aluminium alloy in 3.5 wt.% NaCl solution was investigated, and the corrosion inhibition mechanism was revealed. The influence of AMT concentration on the corrosion inhibition performance was evaluated by potentiodynamic polarization curve and electrochemical impedance spectroscopy (EIS). Surface analysis and surface-enhanced Raman scattering (SERS) spectra were used to study the adsorption process and corrosion inhibition mechanism of AMT on the alloy surface. Polarization curve and EIS results showed that when the AMT concentration was 1.5 g/L, the corrosion current density (icorr) was the lowest and the resistance of adsorption film (Rf) was the largest, illustrating the highest corrosion inhibition efficiency. Moreover, the adsorption kinetics process of AMT was revealed by SERS measurement, and a positive correlation between the SERS intensity and Rf values of AMT after different immersion time was achieved. It indicated that the efficient adsorption of corrosion inhibitors significantly enhanced the corrosion inhibition performance. Density functional theory (DFT) and molecular dynamics simulations were used to give further insight into the adsorption and inhibition mechanism of AMT on the aluminium alloy surface.
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CELLULAR AND MOLECULAR LIFE SCIENCES
·
2022
·Vol. 79
·期 8
·1-18
·
IF 9.207
Huang Ling,Zheng Junping,Sun Guangjun,Yang Huabing,Sun Xiongjie,Yao Xiaowei,Lin Aizhen,Liu Hongtao
Colitis develops via the convergence of environmental, microbial, immunological, and genetic factors. The medicine 5-aminosalicylic acid (5-ASA) is widely used in clinical practice for colitis (especially ulcerative colitis) treatment. However, the significance of gut microbiota in the protective effect of 5-ASA on colitis has not been explored. Using a dextran sulfate sodium (DSS)-induced colitis mouse model, we found that 5-ASA ameliorated colitis symptoms in DSS-treated mice, accompanied by increased body weight gain and colon length, and a decrease in disease activity index (DAI) score and spleen index. Also, 5-ASA alleviated DSS-induced damage to colonic tissues, as indicated by suppressed inflammation and decreased tight junction, mucin, and water–sodium transport protein levels. Moreover, the 16S rDNA gene sequencing results illustrated that 5-ASA reshaped the disordered gut microbiota community structure in DSS-treated mice by promoting the abundance of Bifidobacterium , Lachnoclostridium , and Anaerotruncus , and reducing the content of Alloprevotella and Desulfovibrio . Furthermore, 5-ASA improved the abnormal metabolism of bile acids (BAs) by regulating the Farnesoid X receptor (FXR) and Takeda G-protein-coupled receptor 5 (TGR5) signaling pathways in DSS-treated mice. In contrast, 5-ASA did not prevent the occurrence of colitis in mice with gut microbiota depletion, confirming the essential role of gut microbiota in colitis treatment by 5-ASA. In conclusion, 5-ASA can ameliorate DSS-induced colitis in mice by modulating gut microbiota and bile acid metabolism. These findings documented the new therapeutic mechanisms of 5-ASA in clinical colitis treatment.
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PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2022
·
IF 4.326
Yingying Li,Xueli Ma,Wei Lv,Hong Chen,Linhao Yu,Zewei Ma,Sen Wang,Yongdan Li
Cr-doped ZnAl mixed oxide catalysts (Zn0.75CrAl-x-c) were obtained via calcining the Zn0.75CrAl-x hydrotalcite precursors and were applied in the selective oxidation of 5-hydroxymethylfurfural (5-HMF) to 2,5-furandicarboxylic acid (FDCA). Cr doping significantly enhanced the catalytic activity. A 95.1% 5-HMF conversion with an 88.1% FDCA selectivity was achieved over the Zn0.75CrAl-6-c catalyst at 130 °C under 0.6 MPa oxygen for 4 h. The good performance was associated with the high specific surface area and high oxygen vacancy concentration. Moreover, the Zn0.75CrAl-6-c catalyst was used for five cycles without a significant activity loss indicating excellent stability.
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INDUSTRIAL CROPS AND PRODUCTS
·
2022
·
IF 6.449
Qing Qing,Wenxuan Wu,Xiaoran Tao,Zhuang Ma,Weigang He,Yuheng Tao,Liqun Wang
Aqueous choline chloride/acetone was developed as a green ternary solvent for catalytic conversion of glucose and raw corn stover into 5-HMF. The results illustrated that acidic ChCl solution played a vital role in promoting the tandem isomerization/dehydration reaction of glucose to 5-HMF, while acetone was identified as an efficient extracting solvent to simultaneously remove 5-HMF from the aqueous phase. The composition of the ternary solvent system was found to have a significant impact on the 5-HMF yield, reaction selectivity, and preventing the further degradation of 5-HMF. A competitive 5-HMF yield of 73.3 mol% was achieved from glucose catalyzed by an ultra-low H 2 SO 4 loading of 2 mmol at 190 °C for 10 min in the ternary ChCl-H 2 O-acetone solvent with a mass ratio of 1:2:3. This novel solvent system exhibited good stability, high efficiency, and excellent recyclability, employing in catalytic conversion of both glucose and lignocellulose to produce 5-HMF.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2022
·Vol. 414
·期 28
·7967-7976
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IF 4.478
Jiang Mengyuan,Tian Liang,Su Mengjie,Cao Xiaoqing,Jiang Qiyu,Huo Xiaolei,Yu Chunmei
Serotonin (5-HT) is an essential inhibitory neurotransmitter in vivo that is critical for interneuronal communication of the nervous system. Herein, we constructed an electrochemical cell-sensing platform for 5-HT detection based on MXene/single-walled carbon nanotubes (SWCNTs) nanocomposite. The one-dimensional SWCNTs with good electrical conductivity are uniformly dispersed on the surface and intermediate layers of the two-dimensional MXene to form a tightly heterogeneous heterostructure. The synthesized MXene-SWCNTs could improve the stacking problem of MXene nanosheets and expose more active sites, effectively promoting the conductive properties and electrochemical activity of the composite. The fabricated MXene-SWCNTs/GCE possessed outstanding detection capability for 5-HT with a wide linear range of 4 nM–103.2 μM and a low detection limit of 1.5 nM. Moreover, the sensor was further applied for the real-time monitoring trace amount of 5-HT releasing from different cell lines, which confirmed its promising applications in 5-HT related physiological and pathological fields. Graphical abstract MXene-SWCNTs/GCE was developed and applied for the real-time monitoring of trace amounts of 5-HT secreted from living cells.
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NEUROPHARMACOLOGY
·
2021
·
IF 5.251
Mengwen Shi,Jiaxin Tang,Chengmei Yang,Guanlong Guo,Huaxing Ou,Weihai Chen
Prepulse inhibition (PPI) is disrupted in many neuropsychiatric diseases. Although the inverse agonist of the 5-hydroxytryptamine 2A (5-HT 2A ) receptors, pimavanserin , alleviates PPI deficits in rodents, the precise mechanisms and critical brain areas in the reversal effect of 5-HT 2A receptor inverse agonists remain unclear. The present study aimed to investigate the critical brain areas responsible for the reversal effect of the 5-HT 2A receptor inverse agonist on PPI deficits in male mice. The results showed that intraperitoneal administration of pimavanserin was found to improve normal PPI behavior and reverse PPI deficits elicited by the dopamine D 1 /D 2 receptor nonselective agonist, pergolide . Further, local infusion of pimavanserin into the nucleus accumbens and ventral hippocampus reversed PPI deficits, whereas the same manipulation in the medial prefrontal cortex or ventral tegmental area did not reverse PPI deficits. Overall, the nucleus accumbens and ventral hippocampus are the critical brain areas responsible for the reversal effect of 5-HT 2A inverse agonists on PPI deficits. Such findings contribute to the extensive exploration of the accurate molecular and neural mechanisms underlying the antipsychotic effects of 5-HT 2A receptor inverse agonists, especially the neural circuits modulated by 5-HT 2A receptor activity.
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ENERGY & FUELS
·
2021
·
IF 3.605
Xiangbo Song,Yuhe Liao,Yuting Zhu,Pengyao Sun,Lungang Chen,Longlong Ma,Hongwei Yang,Chenguang Wang
Highly effective production of 5-hydroxymethylfurfural (HMF) from biobased sugar is one of the vital steps for the synthesis of a fuel precursor. In this work, a slow-release effect of proton from a heterogeneous catalyst induced by 1-butyl-3-methylimidazole chloride ([Bmim]Cl) ionic liquids was found and employed to effectively convert biobased fructose to HMF. Under mild conditions of 100 °C and 60 min, a promising HMF yield of 94.6% with a fructose conversion of 99.1% could be achieved in a tetrahydrofuran solvent over the synergy of Amberlyst-15 with [Bmim]Cl, owing to the slow-release effect. Based on extensive control experiments and characterizations, a mechanism of slow release of proton induced by [Bmim]Cl was proposed to better understand the catalytic performance, mainly involving that proton in the −SO3H group of Amberlyst-15 was gradually replaced by the [Bmim]+ of the [Bmim]Cl additive. Additionally, the effect of various parameters (e.g., different ionic liquids and solvents, the loading of the ionic liquid and catalyst, and reaction temperature and time) was systematically investigated. Meanwhile, the stability of Amberlyst-15 and [Bmim]Cl was tested; both could be reused four times. This work provides a novel and highly effective strategy for conversion of biomass-based feedstock toward fuel precursors.
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Journal of the Taiwan Institute of Chemical Engineers
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2021
·
IF 5.876
Xin Li,Guoying Wang,Yawen Hu,Yves Iradukunda,Fenfang Luo,Kaiqiang Yi,Gaofeng Shi
Background In order to replace petrochemicals , there is an increasing demand for environmentally friendly new biochemicals, and 5-hydroxymethyl furfural is one such product. Methods In this paper, sulfonated carbon-titanium dioxide composite nanofiber tube catalyst was prepared by electrospinning and used for the dehydration of carbohydrates into 5-hydroxymethylfurfural in aqueous/ethyl acetate biphasic solution. The catalyst showed good activity in preparing of 5-hydroxymethylfurfural using fructose and glucose as raw materials, with yields of 75.47% and 42.44% of 5-hydroxymethylfurfural. In addition, the catalyst still had catalytic effect when starch and cellulose as the reactants. Significant findings Results showed that the catalytic ability of the catalyst was found to be significantly better than that of a single sulfonated carbon or titanium dioxide, at the same time, the catalyst can be used multiple times and is easy to regenerate. Besides, this study investigated the purification process of 5-hydroxymethylfurfural and finally obtained 95.34 wt.% purity of 5-hydroxymethylfurfural.
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FUEL
·
2021
·
IF 6.609
Jiu Chen,Bin Li,Cheng-Yang Cao,Si-Yuan Zhou,Li-Feng Xie,Dan Zhang
As a novel rich nitrogen content material, 5-Amino-1 H -Tetrazole (5AT) has been considerably popularized in the propellants area recently. The pyrolysis is deemed as the prelude of combustion for solid phase 5AT, which plays a crucial role in combustion process and grasping the pyrolysis characteristics will be more beneficial to further explore the combustion properties of 5AT-based propellant. In this paper, several efforts have been made to enhance the pyrolysis behaviors of 5AT, including employing metal particles as catalysts, and modifying the surface treatment method. Due to the calorific value, the boron and copper powder are selected as the potential catalysts. The solvent/non-solvent (S/NS) and solution recrystallization method are compared to explore the impact of these two modification methods. TG-FTIR technique is applied to capture evolved signals of organic compounds to further deduce the most probable decomposition pathway. Moreover, model-free and model-fitting methods are both employed to calculate the kinetic parameters. The results reveal that, for the modified 5AT samples with the same boron powder catalyst, the activation energies and reaction model (all governed by F4) in the initial stage (100–330 °C) are not significantly impacted by these two modification methods. However, during the latter stages (400–750 °C), the catalytic actions of boron powder appear to be more active, and solution recrystallization method exerts better modification effect, the activation energies was reduced 18.3 kJ/mol and 10.9 kJ/mol respectively for the latter stages compared to S/SN method. Also, the reaction model is transformed from n th -dimensional model (D3) to n th -order model (F1) in the third stage. Particularly, the catalytic actions of copper powder results in the simplification of decomposition steps for 5AT, the activation energies was 138.8 kJ/mol and the catalytic effect of which was improved about 25% compared to the catalytic effect of boron powder in the first stage and its reaction model is also found to be changed into F3. It illustrates that copper powder could embody a better catalytic effect than boron powder under the same modification method. The conclusions of this study could provide a worthwhile guidance for the understanding, designs and applications of the 5AT-based propellants.
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RSC Advances
·
2021
·Vol. 11
·期 59
·37063-37066
·
IF 3.361
Zhengyang Fan,Jie Chen,Huaming Mao,Jungang Yin,Wei Dai,Linlin He,Hongwei Yang
Synthesis of silver nanowires (Ag NWs) has been studied for decades. However, Ag NWs with diameters below 20 nm synthesised by simple and robust approaches are still rarely reported. In this work, Ag NWs with an average diameter of ∼15 nm and an aspect ratio of over 1000 have been prepared by using a Grignard reagent 5-chloro-2-thienylmagnesium bromide as an assistant additive. In particular, the presence of 5-chloro-2-thienylmagnesium bromide is proven to be beneficial for the in situ formation of smaller AgBr and AgCl particles step by step in comparison with traditional inorganic halide ions, and then promote the final growth of ultrafine Ag NWs.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 46
·期 4
·1960-1971
·
IF 3.591
Wen He,Yongbo Xie,Qiang Yin,Zixuan Zhao,Lang Shi,Hongqing Wang
Scientists are still working on developing a “turn-on” fluorescence sensor for Co2+, especially in acidic solutions. A novel “on–off–on” fluorescence sensor based on g-C3N4 nanosheets was designed and prepared in this paper. It was able to detect (2-(5-bromo-2-pyridylazo)-5(diethylamino)phenol (abbreviated to 5-Br-PADAP) and Co2+ quantitatively by quenching and restoring the fluorescence of the g-C3N4 nanosheet system, respectively. Also discussed are the effects of solvent, pH, order of addition, and interaction time of 5-Br-PADAP and Co2+, as well as the concentration range of the object on measurement. Furthermore, in acidic conditions, the sensor demonstrated good selectivity and sensitivity. In the solvent system EtOH : H2O (v/v = 1 : 9, pH = 3), the fluorescence intensity had a good linear relationship with 5-Br-PADAP and Co2+ concentrations in the ranges of 0–15 μM and 0–10 μM, with low detection limits of 64 nM and 44 nM, respectively. Experiments and theoretical calculations were used to describe the interaction characteristics and sensing mechanism. It was eventually successful in detecting Co2+ in environmental samples.
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Yubo Pan,Yali Zhang,Yaoguo Huang,Yun Jia,Linlin Chen
Cyanide wastewater contains highly toxic contaminants such as free cyanide and metal-cyanide complex, it is necessary to find the appropriate degradation technologies. In this study, a simple and effective photocatalyst with enhanced adsorption and photocatalytic activity was developed. A new composite photocatalyst was successfully prepared by solid-state dispersion (SSD) method, which combined graphene oxide (GO), nano titanium dioxide (nano-TiO 2 ) and silicon-based zeolite (ZSM-5). The techniques of scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), N 2 adsorption–desorption test, X-ray diffraction (XRD), ultraviolet–visible diffuse reflectance spectroscopy (UV–Vis DRS), thermogravimetric analysis (TGA), and X-ray photoelectron spectroscopy (XPS) were used to characterize the samples. The experiments with different content of nano-TiO 2 , different wavelengths of light source, different catalyst dosage, control experiments of different materials, and the determination of pH value and zeta potential were also carried out. The results showed that the 3.0 g/L of GTZ-60 (GO/TiO 2 /ZSM-5 composite photocatalyst with a content of 60 wt% TiO 2 ) has the highest photocatalytic degradation efficiency under ultraviolet wavelength which the degradation efficiency of total cyanide and copper could reach 98.73% and 98.96%, respectively. The degradation of total cyanide followed the pseudo-first-order kinetics. The photoelectric properties of GTZ-60 obviously improved the migration and separation of photogenerated electrons ( e − ) and holes ( h + ), so that high photocatalytic efficiency was obtained. XPS analysis showed that cyanide was finally degraded to carbon oxide and nitrogen oxide. Copper and zinc are removed in the form of copper (Ⅱ) and zinc (Ⅱ).
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