JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 5
·6269-6282
·
IF 2.478
Chen Zhangxu,Fu Minglian,Zheng Bingyun,Zhu Danchen,Chen Zefan
The influencing factors of chelator, reaction times, and Yb 3+ /Tm 3+ -doped concentration on the formation of NaYF 4 :Yb,Tm crystals with various morphologies have been investigated and determined. It is found that NaYF 4 :Yb,Tm with various morphologies and different phases can be tuned. Compared with the addition of ethylene diamine tetra acetic acid, hexagonal nanoprism-like β-NaYF 4 :Yb,Tm with a mean length of ~ 1300 nm and diameter of ~ 100 nm is prepared in the presence of oleic acid, which preferentially orients along with the [0001] direction more quickly than others. Systematical research on the emission of Yb 3+ /Tm 3+ -doped NaYF 4 crystals with microrod, hexagonal microprism, and nanoplate has implied that these obtained crystals with unique optical properties are closely related to their morphologies, phases, and sizes. In addition, a possible growth mechanism of co-existence of α- and β-NaYF 4 phases is proposed. It can be expected to illustrate the formation mechanism for the upconversion crystals or other rare-earth upconversion materials and to import these highly luminescent microcrystals or nanocrystals to environmental remediation by full solar energy spectra.
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高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-13
·
IF 10.435
Yin Yipengchen,Li Yongjing,Wang Sheng,Dong Ziliang,Liang Chao,Sun Jiaxin,Wang Changchun,Chai Rong,Fei Weiwei,Zhang Jianping,Qi Ming,Feng Liangzhu,Zhang Qin
Background The recently developed biomimetic strategy is one of the mostly effective strategies for improving the theranostic efficacy of diverse nanomedicines, because nanoparticles coated with cell membranes can disguise as “self”, evade the surveillance of the immune system, and accumulate to the tumor sites actively. Results Herein, we utilized mesenchymal stem cell memabranes (MSCs) to coat polymethacrylic acid (PMAA) nanoparticles loaded with Fe(III) and cypate—an derivative of indocyanine green to fabricate Cyp-PMAA-Fe@MSCs, which featured high stability, desirable tumor-accumulation and intriguing photothermal conversion efficiency both in vitro and in vivo for the treatment of lung cancer. After intravenous administration of Cyp-PMAA-Fe@MSCs and Cyp-PMAA-Fe@RBCs (RBCs, red blood cell membranes) separately into tumor-bearing mice, the fluorescence signal in the MSCs group was 21% stronger than that in the RBCs group at the tumor sites in an in vivo fluorescence imaging system. Correspondingly, the T 1 -weighted magnetic resonance imaging (MRI) signal at the tumor site decreased 30% after intravenous injection of Cyp-PMAA-Fe@MSCs. Importantly, the constructed Cyp-PMAA-Fe@MSCs exhibited strong photothermal hyperthermia effect both in vitro and in vivo when exposed to 808 nm laser irradiation, thus it could be used for photothermal therapy. Furthermore, tumors on mice treated with phototermal therapy and radiotherapy shrank 32% more than those treated with only radiotherapy. Conclusions These results proved that Cyp-PMAA-Fe@MSCs could realize fluorescence/MRI bimodal imaging, while be used in phototermal-therapy-enhanced radiotherapy, providing desirable nanoplatforms for tumor diagnosis and precise treatment of non-small cell lung cancer.
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PubMed
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2021
·Vol. 327
·期 2
·811-819
·
IF 1.371
Du Ziyao,Li Bolin,Jiang Chao,Sun Ruopei,Chen Suwen
A metal–organic framework, UiO-66-NH 2 , was designed, synthesized and characterized in this study. By conducting solvothermal method, Salicylaldehyde (Sal) and 2,4-dihydroxybenzaldehyde (MHBA) were grafted onto UiO-66-NH 2 via post-treatment to obtain the functionalized material UiO-66-Sal and UiO-66-MHBA. The three materials above were characterized, and the effects of solid–liquid ratio, pH, ionic strength, and oscillation time on U(VI) adsorption were studied. The relevant experimental results fitted well with pseudo-second-order kinetic equation and thermodynamic adsorption model.
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高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-23
·
IF 10.435
Wang Haijun,Jia Dianlong,Yuan Dandan,Yin Xiaolei,Yuan Fengjiao,Wang Feifei,Shi Wenna,Li Hui,Zhu Li-Min,Fan Qing
Background Solid tumor hypoxic conditions prevent the generation of reactive oxygen species (ROS) and the formation of DNA double-strand breaks (DSBs) induced by ionizing radiation, which ultimately contributes to radiotherapy (RT) resistance. Recently, there have been significant technical advances in nanomedicine to reduce hypoxia by facilitating in situ O 2 production, which in turn serves as a “radiosensitizer” to increase the sensitivity of tumor cells to ionizing radiation. However, off-target damage to the tumor-surrounding healthy tissue by high-energy radiation is often unavoidable, and tumor cells that are further away from the focal point of ionizing radiation may avoid damage. Therefore, there is an urgent need to develop an intelligent targeted nanoplatform to enable precise enhanced RT-induced DNA damage and combined therapy. Results Human epidermal growth factor receptor 2 (Her2)-specific dimeric affibody (Z Her2 ) mediated cisplatin-loaded mesoporous polydopamine/MnO 2 /polydopamine nanoparticles (Pt@mPDA/MnO 2 /PDA-Z Her2 NPs) for MRI and enhanced chemo-radiotherapy of Her2-positive ovarian tumors is reported. These NPs are biodegradable under a simulated tumor microenvironment, resulting in accelerated cisplatin release, as well as localized production of O 2 . Z Her2 , produced using the E. coli expression system, endowed NPs with Her2-dependent binding ability in Her2-positive SKOV-3 cells. An in vivo MRI revealed obvious T 1 contrast enhancement at the tumor site. Moreover, these NPs achieved efficient tumor homing and penetration via the efficient internalization and penetrability of Z Her2 . These NPs exhibited excellent inhibition of tumor growth with X-ray irradiation. An immunofluorescence assay showed that these NPs significantly reduced the expression of HIF-1α and improved ROS levels, resulting in radiosensitization. Conclusions The nanocarriers described in the present study integrated Her2 targeting, diagnosis and RT sensitization into a single platform, thus providing a novel approach for translational tumor theranostics. Graphic abstract
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PubMed
高影响因子
JOURNAL OF APPLIED ELECTROCHEMISTRY
·
2021
·Vol. 51
·期 5
·803-814
·
IF 2.8
Zhao Ting,Jiang Liang,Liu Jinwei,Wu Hanqiang,Qin Na,Qian Linmao
Potassium persulfate was used as an effective oxidizer for chemical mechanical polishing (CMP) of GCr15 steel. The effects of pH, potassium persulfate content and chelating agents on the CMP performance of GCr15 steel were investigated, and the surface films formed in the potassium persulfate-based slurries were characterized accordingly. It is revealed experimentally that, with pH increasing from 2.0 to 9.0, the material removal rate (MRR) is independent of pH while the surface roughness R a decreases. At pH 8.0, as the potassium persulfate content increases, the MRR linearly increases with a slope of 48 nm min −1 mM −1 , but the surface quality continues to deteriorate accompanied with the black Fe 3 O 4 residue due to the severe corrosion by persulfate. In particular, Fe 2+ and Fe 3+ ions are continuously produced by oxidation of persulfate, and a significant part of Fe 2+ and Fe 3+ further reacts with OH − to form a non-uniform and rough surface film which primarily consists of Fe 3 O 4 . After adding an appropriate chelating agent EDTA, the R a reaches 1.7 nm without any black residue due to the chelation reactions between iron ions and EDTA. The findings suggest that a nano-precision surface finish of bearing steel could be achieved at weakly alkaline pH with persulfate-based slurries. Graphic abstract
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 22
·27852-27863
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IF 4.223
Gao Qiang,Cui Yuchen,Wang Shuaijun,Liu Bin,Liu Chenguang
Sulfate radical−based advanced oxidation processes have received considerable attentions in the remediation of organic pollutants due to their high oxidation ability. In this study, a novel Co 3 O 4 /CeO 2 catalyst was fabricated and employed as a peroxymonosulfate (PMS) activator to generate SO 4 •− for phenol degradation. The Co 3 O 4 /CeO 2 catalyst exhibited a good catalytic performance at a wide pH range of 3.4 to 10.8, and 100% phenol (20 mg/L) was removed within 50-min reaction under optimal conditions with 0.2 g/L catalyst and 2.0 g/L PMS at room temperature. The transformation products and total organic carbon during the degradation process were also determined. The quenching experiments and electron paramagnetic resonance spectra revealed that sulfate radical (SO 4 •− ) rather than other species such as singlet oxygen ( 1 O 2 ) and hydroxyl radical ( • OH) was primarily responsible for phenol degradation in the Co 3 O 4 /CeO 2 /PMS system, and a rational mechanism was proposed. Moreover, the recycling experiments as well as low cobalt leaching concentration manifested satisfactory reusability and stability. The effects of various inorganic anions and natural organic matter in real water matrix on phenol oxidation were further evaluated. We believe that the Co 3 O 4 /CeO 2 composites have promising applications of PMS activation for the degradation of organic pollutants in wastewater treatment.
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高影响因子
CHEMICAL PAPERS
·
2021
·Vol. 75
·期 8
·4093-4098
·
IF 2.097
Yu Shan,Zeng Zhiwen,Guo Cuiping,Jiang Jiu,Pei Dating,Lu Daohuan,Geng Zhijie
Traditional hyaluronic acid (HA) hydrogels are limited by many bottlenecks such as lack of the mechanical strength. In this work, we surprisingly found that with the assistance of small molecule agents (e.g., bis-acrylamide, BIS), the mechanical property of HA hydrogels could be modulated. The HA-BIS hydrogels resulted in stronger mechanical properties increasing from 5.3 kPa (HA hydrogels) to 14.5 kPa (HA-B10 hydrogels). Furthermore, the HA-BIS hydrogels exhibited extraordinary high light transmittance (nearly 100%). The introduction of small molecular agents is advantageous to enhance the mechanical properties of natural hydrogels and pave a new way for wider applications.
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高影响因子
ECOTOXICOLOGY
·
2021
·Vol. 30
·期 5
·885-898
·
IF 2.823
Liu Haisu,Zhang Sanshan,Qiu Ming,Wang Anli,Ye Jianmin,Fu Shengli
The heavy metal lead (Pb) is a contaminant widely distributed in the food chain. In this study, eight weeks of feeding containing Garlic ( Allium sativum ) or Fu-ling ( Poria cocos ) or both, markedly increased the growth index, enzyme activity, and serum index and significantly decreased muscle Pb level in grass carp ( Ctenopharyngodon idella ). Upon Pb exposure, the feeding Garlic or Fu-ling or both possessed the similar effects on improving the function of the antioxidant system and chelating ability. Further, the gene expressions of metal binding proteins ( TF and MT-2 ) in the liver of the three experimental groups were significantly higher than those of the control group, which were all highly up-regulated after Pb exposure. At the same time, the activities of antioxidant enzymes (SOD and CAT) and the content of non-enzymatic substance (GSH) in the liver of the Garlic group, Fu-ling group and mixed group were stable compared to the control group after Pb exposure. Moreover, the reduction of Pb toxicity was manifested by the decrease of Pb content in the muscle, and the stable expression of heat stress proteins ( HSP30 and HSP60 ) and immune-related genes ( TNF-α and IL-1β ). Taken together, the study preliminarily shows that the Garlic and Fu-ling play a role in mitigating the toxicity of Pb in grass carp.
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高影响因子
JOURNAL OF SOLUTION CHEMISTRY
·
2021
·Vol. 50
·期 4
·544-557
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IF 1.677
Dong Shihua,Jia Bing,Chen Xiubin,Jiang Xiaobo
For separation of the azeotropes of water + 2-methyl-3-buten-2-ol by liquid–liquid extraction, methyl tert-butyl ether or butyl acetate or 4-methyl-2-pentanone or 2-ethyl-1-hexanol was selected as the extraction solvent. The liquid–liquid equilibrium (LLE) data for water + 2-methyl-3-buten-2-ol + (methyl tert-butyl ether/butyl acetate/4-methyl-2-pentanone/2-ethyl-1-hexanol) ternary systems at 308.2 K under 101.3 kPa were determined. The distribution coefficient and the separation factor were calculated to evaluate the extraction ability of different solvents. The Othmer–Tobias, Bachman, and Hand equations were applied to verify the reliability of the experimental LLE data. Meanwhile, the experimental LLE data were successfully correlated by the NRTL and UNIQUAC models with the root-mean-square deviations (RMSD) were less than 0.42%.
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高影响因子
Journal of Analytical Science and Technology
·
2021
·Vol. 12
·期 1
·1-8
·
IF 2.769
Li Xiangfei,Qiao Juan,Sun Yongjun,Li Zhiwei,Qi Li
Precisely changing the optical properties of gold nanoclusters (AuNCs) with different ligands offers a promising prospect for highly sensitive and selective drug sensing. In this study, AuNCs were synthesized with d-tryptophan (d-Trp) and its derivatives as the ligands. Optical measurements showed that d-Trp@AuNCs produced higher fluorescence intensity and shorter fluorescence emission wavelength than the d-Trp-derivatives-ligands protected AuNCs, indicating that the ligand-shell rigidity and core-shell charge transfer affected their fluorescent properties. At the excitation wavelength of 370 nm, the emission wavelength of d-Trp@AuNCs was 460 nm. The fluorescence changes revealed the high selectivity of d-Trp@AuNCs for detecting folic acid due to the static quenching and inner filter effect. In the presence of folic acid, the fluorescence of d-Trp@AuNCs was remarkably quenched with good linearity ranging from 6.3-100.0 μM (R2 = 0.997) and a detection limit of 5.8 μM. The proposed assay was successfully utilized to determine the amount of folic acid in human urine with recoveries from 94.3 to 107.3%. This work shows the great potential of d-Trp@AuNCs for detecting folic acid in real bio-samples. It also presents an effective strategy for preparation of the AuNCs with enhanced fluorescence efficiency by regulating the rigidity of the ligands shell and the core-shell charge transfer.
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高影响因子
JOURNAL OF CHEMICAL SCIENCES
·
2021
·Vol. 133
·期 2
·1-8
·
IF 1.573
Fu Guiyu,Weng Huanyuan,Lai Zhuzhi,Lin Zhengzhong,Huang Zhiyong
A rare earth complex Eu(MAA) 3 Phen was prepared with methacrylic acid and o -phenanthroline as ligands under mild conditions. The complex has a fluorescence emission centered at 618 nm with a half-peak width of 15 nm. Since the emission peak of the complex matches the absorption peak of malachite green (MG), the fluorescence of the complex will be quenched by MG through the fluorescence resonance energy transfer effect. The fluorescence testing conditions for MG were optimized based on fluorescence intensity and fluorescence quenching efficiency. The FRET efficiency was calculated to be 0.21. Under the optimal conditions, the response time was only 5 min. Compared with sulfonamides, chloramphenicol and other banned fishery drugs, the complex exhibited the highest quenching efficiency to MG. The linear range was 0.5–20 μmol L −1 , and the detection limit was 117.29 nmol L −1 (3σ/S, n = 9). This complex was used to detect MG residue in aquaculture water, and the recoveries were between 96.10% and 98.76%, indicating that the prepared fluorescent probe could be used for the rapid detection of MG in aquaculture water. Graphical abstract
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高影响因子
JOURNAL OF MATERIALS RESEARCH
·
2021
·Vol. 36
·期 8
·1695-1704
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IF 3.089
Pan Lei,Xue Pengbo,Wang Menglin,Wang Fei,Guo Huaxin,Yuan Xiaosa,Zhong Lang,Yu Jia
Abstract In this study, novel carbon fiber/epoxy (CF/EP) composites with anti-icing properties were made using a combination of octadecylamine modification and hard templating. First, the octadecylamine-modified epoxy resin was sprayed on the surface of CF/EP prepreg. Hierarchical micro/nanostructures were formed on the surfaces of the composites through hot pressing with aluminum templates that had been modified by sandblasting and anodizing. The resulting composites were superhydrophobic, with static contact angles of up to 155° and sliding angles as low as 8°. Superhydrophobicity was maintained after abrading with 400 grit SiC sandpaper. The anti-icing properties of the composites were quantified by measuring droplet freezing time and ice adhesion force. Compared to untreated CF/EP, the surface treatments used here increased the time to freeze a 5 μL surface droplet from 76 to 640 s at − 20 °C, and reduced ice adhesion strength from roughly 74 kPa to 50 kPa. Graphic abstract
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高影响因子
危险品化学品经营许可证（带存储）