EUROPEAN POLYMER JOURNAL
·
2023
·
IF 6
Yuxin Wan,Zhenze Xie,Mingjie Wang,Yuelian Liu,Mubin Zheng,Dong Xu,Chang Du
Osteosarcoma (OS) is one of the most common primary bone malignancies in children and adolescents worldwide. The serious side effects and multi-drug resistance of high-dose chemotherapy have become the major cause of the failure in OS treatment. Curcumin (Cur) is reported to selectively kill OS cells and has a low cytotoxicity on healthy osteoblasts, but its delivery remains a great challenge. Herein, a co-polymer-Cur prodrug (co-prodrug) was developed by polymerizing Cur with hydrophilic polymer modified by succinic anhydride (SA) to explore the physicochemical properties, drug release and potential biological effects for OS treatment. This design endowed the co-prodrug with excellent solubility and stability under different solution conditions (pH = 4.5, 7.4 and 8.5), and improved the release efficiency of reactive oxygen species. Interestingly, co-prodrug exhibited an esterase-triggered rapid drug release in a concentration-dependent manner rather than the well-known acid response. Moreover, co-prodrug could be internalized into cells through endocytosis and significantly inhibit the proliferation of OS cells. Additionally, co-prodrug had no obvious systemic toxicity, and could suppress the OS growth by promoting apoptosis, inhibiting proliferation activity and vascularization in vivo. Our research furnishes a fresh perspective for the formulation design of controlled release of insoluble and instable anticancer agents within tumor cells.
✓ 已验证
产品关联
DOI
高影响因子
IONICS
·
2023
·Vol. 29
·期 11
·4825-4833
·
IF 2.8
Yu Dan,Dong Seng,Liu Qian,Jia Weiyi,Gao Faming,Wang Yatao
The preparation of platinum-free electrocatalysts with ideal oxygen reduction reaction (ORR) activity is of great significance for cost-effective fuel cells. Herein, we synthesize a series of Pd-based (PdFe, PdCo, PdNi, and Pd) nanowires (PdM NWs). Their diameters are about 10 nm. And the lengths are up to even micrometers. The mass activity of the series of Pd-based catalysts followed the descending order: PdNi NWs/C > commercial Pt/C > PdCo NWs/C > PdFe NWs/C > pure Pd NWs/C. The optimal half-wave (E 1/2 ) of PdNi NWs/C (839 mV) is positive shift 138 and 25 mV compared with pure Pd NWs/C (701 mV) and commercial Pt/C (814 mV), respectively. The mass activity (MA) of PdNi NWs/C only dropped 28% after 10,000 potential cycles between 0.6 and 1.1 V versus RHE in acid medium. This work provides a promising and reliable strategy to synthesize high performance Pd-based electrocatalyst, which is promising alternative to expensive Pt-based electrocatalysts for fuel cells. Graphical Abstract TOC: We prepared bimetallic PdNi nanowires, which ORR mass activity higher than pure Pd nanowires and commercial Pt/C in acidic medium.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 33
·15569-15578
·
IF 3.3
Shengbiao Zheng,Jialong Fan,Feilong Yin,Jie Chen,Zhenzhen Hui,Jing Tang,Xuchun Wang,Jiahao Guo
A heterostructured TiO2/Co nanoparticle/N-doped carbon nanotube (TiO2/Co/NCNT) nanomaterial was derived from ZIF-67@TiO2 by calcination at high temperature in an Ar/H2 atmosphere. The obtained TiO2/Co/NCNT composite was made up of numerous dodecahedron-like boxes with twisting nanotubes on surfaces, modified on a glassy carbon electrode (GCE) for the electrochemical determination of tert-butylhydroquinone (TBHQ). The excellent electrocatalytic performance of TBHQ could be owing to the combination of multi-phase composition, fast electron transfer and the constructed Co/Ti multi-active sites. The TiO2/Co/NCNT sensor showed a broad linearity from 0.04 to 100 μM with a low detection limit of 4 nM, and possessed stability, anti-interfering ability and reproducibility. Finally, the analytical utility of the TiO2/Co/NCNT sensor was checked by detecting TBHQ in edible oil.
✓ 已验证
产品关联
DOI
高影响因子
Forests
·
2023
·Vol. 14
·期 5
·965
·
IF 2.9
Gaojun Chen,Yudong Li,Enshan Han,Ziqiang Zhang,Xiaohui Yang,Desheng Zhou,Yanzhen He
The optimization of supercapacitive properties in carbon materials derived from cheap and sustainable wood scraps exhibits great application potential. Herein, in support of interfacial groups, polyaniline nanospheres were in situ constructed in the internal pore structure of wood scraps; further, the B and N elements were imported by carbonized and hydrothermal methods. The doped B regulated the species of N doping to improve the electrical conductivity of carbonized wood scraps, and it endowed a certain pseudo-capacitance. Coupled with the fine double-layer capacitance from the hierarchical structures constructed by carbonized nanospheres and wood scrap channels, a high specific capacitance of 406 F g−1at 0.5 A g−1, high energy density (17.71 Wh kg−1at 250 W kg−1) and cycle stability (93.04% capacitance retention after 10,000 cycles) were performed simultaneously. This study provided a new strategy to improve the supercapacitive performance of bio-carbon materials in terms of structure and conductance.Keywords:wood scrap;B/N co-doping;porous carbon;in situ synthesis;supercapacitor
✓ 已验证
产品关联
DOI
高影响因子
Chem
·
2023
·
IF 23.5
Wenchao Ma,Shunji Xie,Biao Zhang,Xiaoyang He,Xi Liu,Bingbao Mei,Fanfei Sun,Zheng Jiang,Li Lin,Qinghong Zhang,Bin Ren,Gang Fu,Xile Hu,Ye Wang
Electrocatalytic upgrading of CO to value-added multi-carbon (C 2+ ) compounds is a promising approach to efficient carbon utilization. However, current full-cell systems have low energy conversion efficiencies under practical conditions due to the requirement of high cell voltages for an industrially relevant current density. Here, we present a lattice tension strategy to enhance CO chemisorption and carbon–carbon coupling on copper catalysts at high CO coverages, which usually cause excessive dipole-dipole repulsion and are detrimental to C–C coupling. A current density of 1.0 A cm −2 with 84% Faradaic efficiency of C 2+ compounds is achieved at 2.4 V on a spindle-shaped copper with 4% lattice tension. The C 2+ products are formed with nearly 100% selectivity and in a 41% single-pass yield (on a molar carbon basis). This work demonstrates a great potential of electrocatalytic CO reduction for the practical synthesis of high-value chemicals from CO 2 and abundant carbon resources.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2021
·
IF 4.464
Dongfeng Sun,Songmin Lin,Yuan Yu,Fangyou Meng,Gaohui Du,Bingshe Xu
It is still challenging to design and synthesize highly efficient and noble-metal-free electrocatalysts for hydrogen/oxygen evolution reaction (HER/OER). Herein, we developed an in-situ phosphating Co@nitrogen-doping graphene to obtain N and P co-doped carbon-coated cobalt phosphide (CoP@N,P C) that could be used for overall water splitting. The unique 3D porous structure of CoP@N,P C is characterized by a large number of active catalytic sites. High wettability of catalyst in electrolyte solution facilitates the transfer of ions. The synergism between the CoP cores and N, P C shells improves the total hydrolysis performance of the electrocatalyst during the HER and OER. At the current densities of 10 mA/cm 2 (1 M of KOH), the HER overpotential recorded for the CoP@N,P C is 113 mV, and the OER overpotential is 320 mV. The cell voltage of the CoP@N,P C as bifunctional electrode for overall water splitting is 1.67 V (at 10 mA/cm 2 ), which is close to that of the full noble-metal electrode (RuO 2 || Pt/C, 1.58 V). The CoP@N, P C bifunctional catalyst can be potentially used to replace noble-metal electrodes to realize water splitting.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
·
2021
·
IF 3.995
Xiangyan Yun,Jun Zhou,Yaohui Zhu,Xiong Li,Shan Liu,Chen Fang,Mingxia Lv,Denghui Xu
Up-conversion fluorescent materials serve a significant function as the detection materials of temperature sensors . In this study, a series of green-emitting LiLuW 2 O 8 :Yb 3+ , Er 3+ phosphors applied in optical temperature sensing detection were successfully synthesized via the solid-state process in air. The crystal structure, luminescence properties, luminescence mechanism, and optical temperature sensing properties of samples were investigated. LiLuW 2 O 8 :Yb 3+ , Er 3+ phosphor with excitation at 980 nm emits pronounced green emissions owing to the 2 H 11/2 → 4 I 15/2 and 4 S 3/2 → 4 I 15/2 transitions of Er 3+ ions. The whole emission processes of LiLu 0.72 W 2 O 8 :0.24 Yb 3+ , 0.04Er 3+ sample are all two-photon processes. Moreover, we apply thermal coupling levels ( 2 H 11/2 , 4 S 3/2 ) for temperature sensing and the value of sensing sensitivity can reach the maximum of about 1.41% K −1 . All the experimental results imply that LiLuW 2 O 8 :Yb 3+ , Er 3+ phosphors show good potential in temperature sensing.
✓ 已验证
产品关联
DOI
高影响因子
Molecular Catalysis
·
2021
·
IF 5.062
Yu Guan,Yinhe Liu,Qiang Lv,Bo Wang
The selective catalytic reduction of nitrogen oxides (NO x ) by carbon monoxide (CO-SCR) is a promising way to deal with exhaust gasses. And Effective redox cycle and NO dissociation ability are crucial factors for catalytic reduction of NO x . Herein, Fe decorated CeO 2 microsphere catalysts with surface oxygen defect were synthesized by solvothermal and calcination method. Among all catalysts, 0.5Fe-CeO 2 sample showed excellent catalytic performance with efficiency near 96% for NO reduction under the condition of 550 ppmv NO, 1200 ppmv CO, and 40,000 h − 1 of GHSV. It was found that Fe doping could efficiently regulate Ce 4+ /Ce 3+ redox couple and oxygen vacancy for catalytic activity. XRD, Raman, XPS, EPR and H 2 -TPR etc. were employed to explore the physicochemical properties of samples. The results showed that Fe had been incorporated into CeO 2 by XRD, and the results of Raman spectrum and XPS indicated that Ce 4+ /Ce 3+ redox couple existed in 0.5Fe-CeO 2 catalyst. Furthermore, the H 2 -TPR spectrum displayed the formation of oxygen vacancy in the samples. N 2 adsorption-desorption isotherms indicated that the doping of Fe could enlarge the specific surface area, pore volume and pore dimeter of the samples, and thus greatly enhanced the NO adsorption and further NO catalytic reduction on catalysts. In addition, other characterization of physicochemical properties and density functional theory (DFT) calculation were performed to reveal the mechanism of NO + CO reaction. As a result, a mechanism was proposed to elucidate highly efficient NO reduction over the catalysts of Fe decorated CeO 2 microspheres. Finally, the synergistic effects of redox center and oxygen vacancy on catalytic activity enhancement were revealed. This work provides a promising way to the design of efficient catalysts for NO reduction.
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2023
·Vol. 29
·期 1
·41
·
IF 4.6
Jianbin Luo,Xinbo Zhu,Zhiwei Zhong,Geng Chen,Yu Hong,Zijian Zhou
A series of Co-M (M = Fe, Cr, and Mn) catalysts were synthesized by the sol-gel method for soot oxidation in a loose contact mode. The Co-Fe catalyst exhibited the best catalytic activity among the tested samples, with the characteristic temperatures (T10, T50, and T90) of 470 °C, 557 °C, and 602 °C, respectively, which were 57 °C, 51 °C, and 51 °C lower than those of the CoOxcatalyst. Catalyst characterizations of N2adsorption–desorption, X-ray diffraction (XRD), X-ray photo-electron spectrometry (XPS), and the temperature programmed desorption of O2(O2-TPD) were performed to gain insights into the relationships between the activity of catalytic soot oxidation and the catalyst properties. The content of Co2+(68.6%) increased due to the interactions between Co and Fe, while the redox properties and the relative concentration of surface oxygen adsorption (51.7%) were all improved, which could significantly boost the activity of catalytic soot oxidation. The effects of NO and contact mode on soot oxidation were investigated over the Co-Fe catalyst. The addition of 1000 ppm of NO led to significant reductions in T10, T50, and T90by 92 °C, 106 °C, and 104 °C, respectively, compared to the case without the NO addition. In the tight contact mode, the soot oxidation was accelerated over the Co-Fe catalyst, resulting in 46 °C, 50 °C, and 50 °C reductions in T10, T50, and T90compared to the loose contact mode. The comparison between real soot and model Printex-U showed that the T50value of real soot (455 °C) was 102 °C lower than the model Printex-U soot.Keywords:soot oxidation;Co-based catalyst;NO;real soot;contact mode
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Xueling Wang,Yanwei Li,Xinhui Jin,Guang Sun,Jianliang Cao,Yan Wang
Gas sensor constructed with metal oxide semiconductor (MOS) has attracted a growing concern owing to its feasibility for rapid detection of various harmful and pollutant gases . However, the sensors made of pure MOS usually suffer from the drawbacks of high working temperature, low sensitivity and poor selectivity. Herein, we propose a Co-doping strategy to upgrade the gas sensing performance of In 2 O 3 . To expound it, Co-doped In 2 O 3 porous nanospheres (Co-In 2 O 3 PNSs) with the diameter of ∼120 nm was prepared from home-made In(OH) 3 NSs via a soaking-lyophilization-calcination method and their sensitive performance towards several volatile organic compounds (VOCs) was investigated in detail. Compared to pure In 2 O 3 sensor, the best Co-In 2 O 3 sensor (with optimized 0.5 mol% Co) exhibited outstanding improvements in triethylamine (TEA) sensing performance, especially including lower optimal working temperature (OWT: 220 °C vs 320 °C), higher response (R a /R g : 3500 vs 60 for 10 ppm TEA), and better selectivity (selectivity coefficient S TEA /S ethanol : 400 vs 1850). Besides, an interesting selectivity transformation from ethanol to formaldehyde was also observed after Co doping. These improvements of Co-In 2 O 3 PNSs were mainly attributed to their reduced crystallite size, increased oxygen vacancy concentration, narrowed bandgap, as well as upshifted Fermi level , whose mechanism was discussed.
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2023
·
IF 7.4
Xingye Zeng,Cunhui Lin,Qinggang Ren,Shufeng Shan,Hanlu Wang
Developing a highly efficient catalyst is one of the important topics in the field of oxidative desulfurization from liquid fuels. In this study, the composite metal oxide catalysts (CuO-MgO) with co-catalyst MgMoO 4 were prepared by co-precipitation method with simple process, high efficiency and good performance and their structures characterized. An efficient extractive catalytic oxidative desulfurization (ECODS) system for liquid fuel was successfully developed on the basis of as-prepared CuO-MgO-MgMoO 4 (CuMgMo) as the catalyst, sodium hypochlorite (NaClO) as the oxidant, and acetonitrile as the extractant. Taking the n -decane and n -tetradecane containing dibenzothiophene (DBT) as the test model oil sample, the main parameters influencing desulfurization performance were examined in detail, such as the molybdenum content, the dosage of CuMgMo, the reaction temperature, the initial S-concentration, the different extractants, the volume ratio of extractant to oil, the different oxidants, and the molar ratio of NaClO to DBT . Based on optimized desulfurization reaction conditions, the model oil containing different sulfur compounds (benzothiophene, 4-methyldibenzothiophene, and 4,6-dimethyldibenzothiophene) and the real oil (straight-run gasoline, straight-run kerosene, and straight-run diesel) were further tested. Based on the free radical trapping experiments and the calculation of density functional theory, the reaction mechanism was deeply explored. The results showed that the de-electron reaction of DBT was mainly catalyzed by MgMoO 4 and the reaction of HClO obtaining electron was mainly catalyzed by CuO. MgMoO 4 plays an assisting role in improving the catalytic reaction rate. This work will provide a useful reference for the construction of efficient ECODS system using composite metal oxides.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Yunrui Zhang,Hong Zhang,Yinuo Zhao,Xingyan Han,Haijun Wang,Yongjun Gao
Boron and nitrogen co-doped carbon materials were synthesized by using sustainable chitin as precursor and boric acid as recyclable template. The carbon product possessing high surface area (1100–1400 m 2 /g) and micro- and mesoporous structure exhibited excellent catalytic activity in the oxidation of benzylic C H bond of ethylbenzene. Characterizations demonstrate that there are boron nitride (BN) bonds in carbon product achieved at higher calcining temperature. Experimental results and density functional theory (DFT) calculations suggest that the boron nitride domains locating in the carbocatalyst are essential to its catalytic activity. B dopants could anchor active oxygen-containing groups and then transfer oxygen atoms to substrate during the whole catalytic process.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）