RARE METALS
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2025
·
IF 11
Wang Cong-Ying,Shi Ying-Ge,Lin Yu-Chen,Tang Zhi-Yong,Lu Si-Yu
Bacterial infections have seriously impaired the wound healing. Despite numerous antibiotics have been developed to inhibit bacteria, the emergence of antibiotic resistance necessitates a rethinking of the public health crisis. In this study, we introduce the carbon dots derived from metformin and dopamine (MD-CDs) as a novel approach to promote the healing of bacterial-infected wound. Through a hydrothermal reaction, the regularly spherical MD-CDs were prepared. Owing to their inherent antibacterial property, MD-CDs effectively inhibited the wound infection and expedited the transition from the inflammation phase to the healing phase in infected wound. Additionally, MD-CDs enhanced the proliferation and migration of L929 cells, which is crucial for wound tissue regeneration. Following the treatment of infected full-thickness skin wounds, MD-CDs effectively promoted the collagen deposition and regeneration of hair follicle in the healing phase. Consequently, MD-CDs represent a bioactive nanomaterial exhibiting inherent antibacterial, offering a promising alternative for the treatment of infected wounds. Graphical abstract
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Ullah Inam,Ren Jie,Zeng Feng,Lou Hao,Abbasi Zeeshan,Ahmed Syed Musab,Wu Wenlong,Wang Zhandong
One significant obstacle to the colonization of Mars is the high cost of excess launch mass required for long-term space travel and the establishment of a settlement. The Sabatier reaction provides a means for recycling water and rocket propellant that dramatically reduces the supplement. Herein, we introduce a membrane Sabatier system by integrating a catalytic reactor with an H 2 O vapor permselective membrane tube. We achieve a substantial increase in CO 2 conversion, a high CH 4 yield and excellent long-term stability via highly efficient in-situ water removal. Furthermore, the system’s robustness under intermittent power supplies, and its adaptability across a wide range of reaction conditions, makes it highly compatible with the electrolytic hydrogen production system, which is subject to unstable solar energies. The advent of the membrane Sabatier system heralds a transformative approach to the recycling of H 2 O and rocket propellant in long-term interplanetary exploration.
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高影响因子
MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 11
·1-16
·
IF 5.3
Feng Luping,Li Xinfeng,Wang Jianghong,Chen Enjun,Fan Yujie,Jin Leyao,Tang Peisong,Zhang Lixiang
A visible-light-powered photoelectrochemical (PEC) sensor was devised for chlorpyrifos (CPs) determination using metallic Bi-decorated BiVO 4 nanosheets (Bi@BiVO 4 NSs) with localized surface plasmon resonance (SPR) synthesized via a one-step hydrothermal method. It was observed that Bi@BiVO 4 -based PEC sensors exhibit significantly enhanced PEC responses over pristine BiVO 4 due to the collaborative effect of metallic Bi’s SPR phenomenon and BiVO 4 ’s visible-light-driven properties. Furthermore, the addition of CPs selectively suppresses the photocurrent signal of the sensor due to the in-situ formation of Bi-CPs complexes, which hindered electron transfer through specific chelation reactions between Bi sites and CPs. The designed PEC sensor achieved high-sensitivity detection of CPs, with a linear concentration range from 0.02 to 20 ppb and a detection limit of 0.01 ppb. These attributes may offer a blueprint for developing diverse PEC sensing systems to monitor various environmental pesticide contaminants like CPs by synergistic integration of visible-light-responsive BiVO 4 and SPR-active metallic Bi. Graphical
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2025
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IF 0
Wu Guizhi,Duan Xuebin,Xu Hongqing,Han Chunyu,Liu Jing,Yan Boyin,Li Jincheng,Wang Jianming,Wang Songxue
The UV/SPC process was employed for the removal of rhodamine B (RhB), and the influences of reaction parameters and natural water components on the degradation of RhB were systematically studied. The results demonstrate that RhB can be efficiently eliminated in the UV/SPC system compared to using UV photolysis or SPC oxidation alone, with •OH and CO 3 •− being the main radicals to degrade RhB. The degradation efficiency of RhB was enhanced with increasing SPC concentration but decreased with increasing initial RhB concentration. Moreover, the degradation efficiency of RhB decreased with the increasing initial pH. When pH increased from 3 to 11, the degradation efficiency of RhB declined from nearly 100 to 81.93% within 20 min. Natural organic matter (NOM) and anions (Cl − and HCO 3 − ) exhibited an inhibitory effect on the degradation of RhB in the UV/SPC system, and the inhibitory effect was aggravated with the increase of NOM and anion concentrations. Consequently, there was a decrease in the degradation efficiency of RhB in the UV/SPC system in real water compared to pure water. The byproducts generated during the degradation of RhB were attributed to hydroxylation, N -deethylation, and C-O bond cleavage. Some intermediate products from RhB degradation still pose relatively high environmental risks, while most have low environmental hazards.
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CELLULOSE
·
2025
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IF 4.8
Cui Xiaolong,Yu Yatong,Wang Xiaoying,Wang Shoujuan,Zhang Chunling,Kong Fangong,Zhao Joe R.,Fatehi Pedram
Bacterial cellulose (BC), a natural biopolymer, exhibits excellent biocompatibility and mechanical properties but lacks inherent antibacterial and hemostatic properties, which hinders its application in wound dressing. In this study, we developed a novel BC-derived hydrogel loaded with nano-silver (AgNPs) and Panax notoginseng (PN) powder (BC@AgNPs/PN) to address these limitations. The hydrogel exhibited exceptional porosity, eco-friendly degradability (33% degradation within 35 days), outstanding mechanical strength (52 kPa), and water retention capacity (1622%), making it suitable for accommodating various body movements and maintaining a moist environment conducive to wound healing. The hydrogel demonstrated excellent antibacterial properties, achieving 99% and 98% inhibition against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ), respectively. The incorporation of PN significantly enhanced its hemostatic performance, with a coagulation index of 41%. The hydrogel demonstrated excellent biocompatibility with L929 cells, with cell viability exceeding 85%, highlighting its potential in biomedical applications. Additionally, in vivo studies using a mouse model confirmed its effective promotion of wound healing, with a wound healing rate exceeding 90% within 18 days. Overall, the developed BC-derived hydrogel exhibits superior antibacterial activity, efficient hemostatic properties, and excellent biocompatibility, making it a promising candidate for advanced wound dressing applications. Graphical abstract
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MARINE BIOTECHNOLOGY
·
2025
·Vol. 27
·期 6
·155
·
IF 2.8
Xiang Jionghua,Wu Qiming,Xu Kai,Liu Qun,Nie Yusen,Weng Wuyin,Zhang Yucang,Wang Haiqi
At present, shells have been used to incubate Pyropia haitanensis ( P. haitanensis ) shell-boring conchocelis. To develop a more convenient substrate for P. haitanensis conchocelis cultivation, a novel P. haitanensis shell-boring conchocelis culture substrate (CaCO 3 /LPE/CA) was developed from calcite, low-density polyethylene, and calcium alginate. The mechanical properties and stability of CaCO 3 /LPE/CA, including implanting density (ID) and Yield per unit area, were tested. The results showed that the CaCO 3 /LPE/CA met practical P. haitanensis shell-boring conchocelis breeding application requirements. P. haitanensis was successfully cultured on CaCO 3 /LPE/CA, and its life cycle was observed through biomicroscopy and scanning electron microscopy (SEM). After conchospores was succrssfully reseased from P. haitanensis conchosporangial branch, the movement and germination of conchospores were also observed. The yield of conchospores per unit area of optimized CaCO 3 /LPE/CA reached 369.6 × 10 3 conchospores/cm 2 , making it a suitable candidate for P. haitanensis shell-boring conchocelis cultivation. Overall, CaCO 3 /LPE/CA exhibits great potential as a marine bioactive material, and the process and cost of P. haitanensis culture breeding could be simplified due to its comprehensive characteristics.
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Microsystems & Nanoengineering
·
2025
·Vol. 11
·期 1
·211
·
IF 9.9
Wei Yiming,Chen Wanying,Ma Yukun,Zhao Yixin,Dai Zhen,Liu Haoyu,Zhang Shanshan,Zhou Yue,Ye Xuesong,Liang Bo
Real-time glucose monitoring and adaptive insulin administration are critical for effective diabetes management. Minimally invasive microneedle-based glucose monitoring sensors offer a promising approach but suffer from signal drift due to tissue reactions, inconsistent implantation, or mechanical damage to their sensitive layers during insertion. Moreover, microneedle-based insulin delivery faces limitations in achieving accurate and quantitatively controlled release due to its passive response mechanism. Here, we report a minimally invasive platform integrating a multiplexed glucose biosensor array with on-demand insulin delivery for precise glycemic control. To prevent the impact of potential individual microneedle failure post-insertion, the system incorporates a redundant sensing array comprising four individually addressable electrodes functionalized with glucose oxidase, providing robust and reliable glucose measurements. Simultaneously, an addressable drug-release array of eight microneedles loaded with insulin within redox-responsive hydrogels enables localized electrochemical triggering for spatiotemporally controlled insulin release. These components are coordinated via a wireless interface leveraging real-time multi-channel ADC data processing and Bluetooth transmission to dynamically activate insulin microneedles based on algorithmic glycemic thresholds. The platform’s redundant sensing design enhances system reliability, maintaining accurate glucose monitoring even in case of individual sensor failure, while its on-demand insulin release enables real-time glycemic regulation. Ultimately, in vivo experiments in rats were conducted to verify the system’s efficacy. By synergizing multiplexed biosensing, fault tolerance, and programmable drug delivery, this platform addresses critical limitations of current glucose monitoring systems and establishes a demonstration prototype for next-generation closed-loop bioelectronics.
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COLLOID AND POLYMER SCIENCE
·
2025
·
IF 2.3
Mao Xiaoxi,Zhou Haijing,Wang Xiaotian,Jiao Enguang,Gao Meng,Wang Kunhua,Guan Meili,Ning Liangmin,Fu Min,Chen Wei
Ribavirin (RBV) is a broad-spectrum antiviral agent with proven clinical efficacy. Improper RBV disposal however may cause substantial ecosystem contamination and human health hazards, attributable to its confirmed developmental toxicity. Consequently, operationally simple RBV extraction strategies urgently needed for environmental waters. In this work, leveraging the superior chemical durability, extensive active surface area, and eco-friendly nature of biomass-activated carbon (BAC), a novel molecularly imprinted polymer (PC@PEI/PBA/MIPs) was engineered through dopamine-mediated surface polymerization using rapeseed pollen carbon (PC) as the substrate, specifically designed for selective RBV separation. Furthermore, branched polyethyleneimine (PEI) was covalently grafted onto the porous carbon surface to add the density of boronic acid groups, resulting in a high density of recognition sites in a mild environment. The adsorption experiments show that PC@PEI/PBA/MIPs has a significant binding efficiency (158.03 mg /g) for RBV, and can quickly reach the adsorption equilibrium time within 60 min, with good selectivity and regeneration performance. Finally, PC@PEI/PBA/MIPs were used to capture RBV from real water samples, achieving > 80% recovery efficiency. The prepared PC@PEI/PBA/MIPs plays a decisive role in the separation and enrichment of RBV in complex systems.
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Journal of Environmental Health Science and Engineering
·
2025
·Vol. 23
·期 2
·40
·
IF 2.8
Suanon Fidèle,Kanhounnon Wilfried G.,Hounfodji Jean Wilfried,Kiki Claude,Zeng Qiaoting,Kpotin Gaston,Yete Pelagie,Tometin Lyde Arsène Sewedo,Atohoun Yacolé Guy Sylvain,Yu Chang-Ping,Mama Daouda,Qian Sun
Mitigating the pollution of water by emerging contaminants (ECs) presents a critical environmental challenge that demands innovative, effective, cost-efficient, and sustainable strategies. In this study, the potential of TiO₂-modified activated carbon (AC) for the sequestration of ECs from water was evaluated through a combined experimental and in silico approach, using molecular modeling based on density functional theory (DFT). Unmodified AC removed 67.76–82.09% of ECs such as carbamazepine, flumequine, clarithromycin, azithromycin, and roxithromycin, and 44.54–52.27% of sulfamerazine, sulfamethoxazole, sulfamonomethoxine, trimethoprim, and levofloxacin. Incorporating TiO₂ and utilizing sunlight improved removal efficiencies to 93.09–99.91%. The hydrophobicity of contaminants significantly influenced adsorption. Kinetic and isotherm analyses indicated chemical interaction-driven, monolayer adsorption, with the Langmuir model fitting best (R² = 0.9856–0.9975). Textural analysis of TiO₂–AC (10% TiO₂) revealed a surface area of 557.72 m²·g⁻¹ and a pore volume of 0.317 cm³·g⁻¹, supporting its high adsorption potential. Fourier transform infrared spectroscopy and molecular modeling identified functional groups facilitating adsorption, while DFT provided insights into energetic and non-covalent interactions (NC-interaction) including hydrogen bonding, van der Waals forces (VDW-forces), and charge transfer that occur during the process. TiO₂-modified AC demonstrates high efficiency for pharmaceutical removal from water, highlighting great promise as a sustainable and advanced adsorbent material, offering practical solutions for tackling diverse water pollution challenges.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2025
·
IF 1.6
Ji Mingbo,He Jiexian,Yang Dacan,Cui Yiqun,Zhang Wenxue,Liu Xiaolong,Ma Fuqiu,Feng Haining,Wang Guixiang
The growing demand for high-specific-activity 177 Lu necessitates efficient Yb/Lu separation. This study synthesized and characterized novel phosphorus-containing levextrel resins. HEH(EHP)-based resin achieved over 99% Lu adsorption under low acidity with a separation factor ( SF Yb/Lu ) exceeding 3, while HDEHP-based resin showed faster kinetics. Using the optimized HDEHP/HEH(EHP)-XAD-7 resin, a three-cycle process yielded 94.98% Lu recovery, and a secondary separation achieved 83.37% Yb removal. These findings demonstrate the resin’s high efficacy for producing high-purity 177 Lu. Graphical abstract
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Journal of Inorganic and Organometallic Polymers and Materials
·
2025
·
IF 4.9
Feng Ya,Guo Xinyuan,Tan Rui,Ren Junchao,Huang Mengde,Chen Jianlong,Zhang Qingfa
Achieving a balance among degradation behavior, mechanical performance, and thermal stability is critical for meeting application requirements and ensuring sustainability, particularly for composites with inherent property limitations. Straw derived hydrothermal carbon microspheres were proposed to reinforce citrate ester composites and the ultimate goal was to seek an approach to achieve the balance between properties and sustainability of biocomposites. The results showed that the network structure within the composites was formed through strong ester and hydrogen bonding, which was directly responsible for their enhanced tensile properties. The resultant composites exhibited better degradation properties because the addition of hydrothermal carbon microspheres accelerated the degradation of citrate ester in both aqueous and phosphate-buffered saline environments. Adding hydrothermal carbon microspheres decreased the glass transition temperature due to the increase of the free volume and interfacial pathways, and increased the thermal stability due to the delay of maximum decomposition peak temperature of citrate ester. Among all the composites samples, the composite containing 3% HCS exhibited the most balanced and superior overall properties with the degradation rate of 37.56%, tensile strength of 1.25 MPa, tensile modulus of 0.23 MPa, and elongation at break of 52.69%. The mentioned composite is expected to provide referable process and properties in the composites field with specific requirements.
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Nature Communications
·
2025
·
IF 15.7
Wang Yanqiu,Tan Lu,Yang Yi,Duan Hongli,Liu Chao,Zhao Jing,Zhou Yue,Li Changqing,Liu Minghan
Intervertebral disc degeneration is a major cause of low back pain and is driven by a vicious cycle of reactive oxygen species (ROS), ferroptosis, and inflammation, afflicting millions of people worldwide. Breaking this cycle represents a significant therapeutic challenge. Here, we develop a ROS-responsive hydrogel loading a resident nanozyme system composed of nucleus pulposus cell membrane-coated black phosphorus@cerium oxide to disrupt this degenerative cascade. Specifically, the nanozyme exhibits a self-sustaining cerium redox cycle due to the incorporation of black phosphorus nanosheets into cerium oxide, conferring durable antioxidant capacity for scavenging ROS. Furthermore, it suppresses the inflammatory cytokine IL6 by inhibiting HuR-mediated mRNA stabilization, thereby blocking the pro-inflammatory and pro-ferroptotic IL6/STAT3 axis. Together, this dual mechanism enables our nanozyme-functionalized hydrogel to break the ROS-ferroptosis-inflammation feedback loop, thus effectively promoting structural and functional disc repair.
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