JOURNAL OF ALLOYS AND COMPOUNDS
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2017
·
IF 3.133
Xin Wang,Xiaotao Yuan,Xiangye Liu,Wujie Dong,Chenlong Dong,Minghe Lou,Juncen Li,Tianquan Lin,Fuqiang Huang
Nitrogen-doped black TiO 2 (N x :TiO 2−x ) recently attracted attention as a novel photocatalyst . It has higher electrical conductivity and more suitable energy level for oxygen reduction and hydrogen evolution than pure TiO 2 due to the presence of Ti 3+ species. The unique electronic structure and strong metal-support interaction make it a candidate support for Pt-based electrocatalyst . Carbon is universal as support of Pt-based electrocatalyst. However, it is restricted to the poor durability and bad methanol tolerance. On the contrary, the chemical stability of nitrogen-doped TiO 2 contributes to the higher durability and methanol tolerance of Pt/N x :TiO 2−x than Pt/C catalyst. Monodisperse Pt nanoparticles are loaded on N x :TiO 2−x by a facile borohydride reduction method. The Pt/N x :TiO 2−x hybrid shows better oxygen reduction reaction (ORR) activity with the half wave potential of 0.78 V ( vs. reversible hydrogen electrode) than Pt and good hydrogen evolution reaction (HER) performance with 19 mV onset overpotential, similar to Pt/C catalyst. More importantly, Pt/N x :TiO 2−x catalyst has robust durability and higher methanol tolerance than Pt/C catalyst. All these electrostatic performances stem from the suitable energy level for ORR and HER and the strong interaction between Pt and N x :TiO 2−x support. This hybrid material is a promising candidate for the fuel cell in the future.
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PLoS One
·
2017
·Vol. 12
·期 1
·e0170013
·
IF 2.806
Sheng Liu,Wenjie Gao,Yao Wang,Zhenyu He,Xiaojun Feng,Bi-Feng Liu,Xin Liu
Monitoring glycosylation of the mAbs have been emphasized and routinely characterized in biopharmaceutical industries because the carbohydrate components are closely related to the safety, efficacy, and consistency of the antibodies. In this study, the comprehensive glycan profiling of a biosimilar candidate of cetuximab was successfully characterized using Normal phase high-performance liquid chromatography (NP-HPLC) in combination with Matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS). The presence of minor N-linked glycans containing sialic acid lactone residues (NeuAcLac) was observed in the biosimilar for the first time, which could influence the quantitative analysis of sialylated glycans and interfere with quantification of neutral glycans when it was analyzed by high performance liquid chromatography fluorescence (HPLC-FL). To overcome this issue, mild alkali treatment was used to hydrolyze lactone of the sialic acid to their neutral formation, which had no impact on the analysis of other glycans before and after the treatment. As a result, the mild alkali treatment might be helpful to obtain quantitative glycan profiling of the mAbs drugs with enhanced accuracy and robustness.
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TENSIDE SURFACTANTS DETERGENTS
·
2017
·Vol. 54
·期 1
·54-63
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IF 0.869
Xu Li,Lan Wu,Qiong Tang,Jinxiang Dong
Glycerol, derived from biodiesel production, is a renewable feedstock for the production of value-added chemicals. Herein, we report an investigation of the acetalization of glycerol with n -octanal by homogeneous acid catalysis in the absence of a solvent, using p -dodecylbenzenesulfonic acid, p -toluenesulfonic acid, and sulfuric acid, respectively, as catalysts. p -Dodecylbenzenesulfonic acid, a surfactant-type Brønsted acid, proved to be an excellent catalyst capable of efficiently promoting the reaction under solvent-free conditions, and the yields of glycerol acetals reached 99% under the optimal conditions. The distribution of five- and six-membered cyclic acetal regioisomers varied depending on the reaction time and temperature. Moreover, the amphiphilic properties of the products, with different ratios of five- to six-membered cyclic acetals, have been evaluated by surface tension measurements.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2016
·
IF 3.014
Ting Lü,Shuang Zhang,Dongming Qi,Dong Zhang,Hongting Zhao
A class of thermosensitive and reusable magnetic nanoparticles (MNPs) was developed for removing emulsified oil droplets from aqueous media. Magnetic iron oxide (MIO) nanoparticles were prepared with a coprecipitation method, followed by coating with silica layer and further modification with γ-methacryloxypropyl triisopropoxidesilane (MPS). Poly( N -isopropylacrylamide) (PNIPAM) molecular chains were then anchored onto the surfaces of MNPs via a “grafting through” reaction. The efficiency of synthetic MNPs for treating emulsified oily wastewater was evaluated as a function of dosage, pH, temperature and reusability. PNIPAM-grafted MNPs exhibited high demulsification efficiency at lower temperature, while decreased dramatically when the temperature exceeded the lower critical solution temperature (LCST) of PNIPAM (∼33 °C); moreover, MNPs could be facilely regenerated by rinsing with hot water and could be reused up to 7 cycles. The results indicated that PNIPAM-grafted MNPs could potentially be a new promising and environmentally friendly approach for effectively treating emulsified oil in wastewater.
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Polymers
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2017
·Vol. 9
·期 7
·301
·
IF 3.364
Xiaoyan Tu,Chao Meng,Zhe Liu,Lu Sun,Xianshuo Zhang,Mingkui Zhang,Mingrui Sun,Liwei Ma,Mingzhu Liu,Hua Wei
Polymers with advanced topological architectures are promising materials for wide applications due to their structure-generated unique properties different from that of the linear analogues. The elegant integration of stimuli-responsive polymers with such advanced architectures can create novel materials with virtues from both moieties, are thus a hot subject of research for both fundamental and practical investigations. To fabricate cyclic brush polymer-based intelligent materials for biomedical applications, herein, we designed and synthesized thermo-sensitive cyclic brush polymers with poly(N-isopropylacrylamide) (PNIPAAm) brushes by controlled living radical polymerization using cyclic multimacroinitiator. The thermo-induced phase transition behaviors of the resultant cyclic brush polymers with different compositions were investigated in detail by temperature-dependent optical transmittance measurements, and compared with the properties of bottlebrush and linear counterparts. Interestingly, the cloud point transition temperature (Tcp) of cyclic brush PNIPAAm could be regulated by the chain length of PNIPAAm brush. Although the bottlebrush polymers with the same composition exhibited similarly structurally dependentTcps behaviors to the cyclic brush polymers, the cyclic brush PNIPAAm did show higher critical aggregation concentration (CAC) and enhanced stability against dilution than the bottlebrush counterpart. The readily tailorableTcps together with the ability to form highly stable nanoparticles makes thermo-sensitive cyclic brush PNIPAAm a promising candidate for controlled drug delivery.Keywords:cyclic brush polymer;thermo-sensitivity;poly(N-isopropylacrylamide)
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Journal of Materials Chemistry A
·
2016
·Vol. 5
·期 1
·266-274
·
IF 8.262
Man Huang,Kan Mi,Junhao Zhang,Huili Liu,Tingting Yu,Aihua Yuan,Qinghong Kong,Shenglin Xiong
To tackle the issue of the low specific capacity (372 mA h g−1) of graphite as the anode material for lithium-ion batteries (LIBs), an effective and controllable strategy was developed to construct porous bimetallic Co/Zn embedded N-doped carbon (Co–Zn/N–C) polyhedral nanocages via annealing a ZIF-8@ZIF-67 precursor at 800 °C under Ar atmosphere. The results clearly displayed that metallic Co and Zn particles are uniformly dispersed in the carbon matrix. Porous Co–Zn/N–C polyhedral nanocages have a large specific surface area of 349.12 m2 g−1 and contain plenty of micropores and mesopores, which benefit from the carbonization of organic ligands and the catalytic effect of cobalt in the calcination process. As anodes for LIBs, the porous Co–Zn/N–C polyhedral nanocages showed an initial discharge capacity of 809 mA h g−1 and a capacity retention of 702 mA h g−1 after 400 cycles at a current density of 0.2 A g−1. Furthermore, a reversible capacity of 444 mA h g−1 was obtained at a much higher current density of 2 A g−1. The improved electrochemical performance was attributed to the synergistic effect of Zn and Co, the unique porous hollow structure as well as N doping, which relieved the impact of volume changes, maintained perfect electrical conductivity throughout the electrode and enhanced the electrochemical activities of lithium storage.
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SENSORS
·
2016
·Vol. 16
·期 11
·1874
·
IF 2.033
Qi Xiao,Shuangyan Lu,Chusheng Huang,Wei Su,Shan Huang
Based on N-doped carbon dots/β-cyclodextrin nanocomposites modified glassy carbon electrodes (N-CDs/β-CD/GCE), an effective electrochemical sensor for enantioselective recognition of tryptophan (Trp) enantiomers was developed by differential pulse voltammograms (DPVs). Fluorescent N-CDs were synthesized through a hydrothermal method and characterized by spectroscopic approaches. The N-CDs/β-CD nanocomposites were efficiently electrodeposited on the surface of GCE through C–N bond formation between N-CDs and electrode. The obtained N-CDs/β-CD/GCE was characterized by multispectroscopic and electrochemical methods. Such N-CDs/β-CD/GCE generated a significantly lower Ip and more negative Ep in the presence ofl-Trp in DPVs, which was used for the enantioselective recognition of Trp enantiomers. The N-CDs/β-CD nanocomposites showed different binding constants for tryptophan enantiomers, and they further selectively bonded withl-Trp to form inclusion complexes. This N-CDs/β-CD/GCE combined advantages of N-CDs with strong C–N binding ability and β-CD with specific recognition of Trp enantiomers to fabricate a novel sensing platform for enantioselective recognition of Trp enantiomers. This strategy provided the possibility of using a nanostructured sensor to discriminate the chiral molecules in bio-electroanalytical applications.Keywords:N-doped carbon dots;β-cyclodextrin;tryptophan enantiomers;enantioselective recognition;differential pulse voltammetry
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2024
·
IF 2.2
Fangfang Dai,Jiangting Cao,Na Liu,Meiyuan Peng,Chen Wang
In order to separate n-hexane/ethyl acetate (EA) produced in industrial production, the liquid–liquid extraction was used to separate the azeotropic system with sulfolane , 1,2-propanediol and dimethyl sulfoxide (DMSO) as extractants. The liquid–liquid equilibrium (LLE) data of the n-hexane + EA + sulfolane/1,2-propanediol/DMSO were measured at 303.15 K, 313.15 K and 323.15 K. The extraction capacity of the extractants were evaluated by the distribution coefficient (D) and separation factor (S). The LLE data were correlated using the NRTL and UNIQUAC thermodynamic models to obtain binary interaction parameters. The root mean square deviation (RMSD) were all less than 0.02 indicating that the two models were suitable for the phase equilibrium behavior. GUI-MATLAB software was used to test the reliability of the regressed binary interaction parameters. The Dmol 3 module of the Materials Studio was used to analyze σ-profile of n-hexane, EA and extractants and to assess the interaction energy between the components. The results show that sulfolane is the best extractant for the separation of n-hexane + EA.
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Applied Sciences-Basel
·
2024
·Vol. 14
·期 20
·9232
·
IF 2.5
Tao Jia,Jinpeng Yang,Jia Yu
Understanding the density of CO2+n-decane is crucial for designing and operating CO2capture, transport, and storage. The safety and effectiveness of CO2burial is directly affected by the density of CO2+n-decane mixtures. The liquid densities of CO2(1) +n-decane(2) mixtures with mole fractions of CO2x1= 0, 0.2032, 0.4434, 0.7589, and 0.8947 were measured using a vibrating tube densimeter. The combined expanded uncertainties of density with a level of confidence of 0.95 are estimated to be 0.6 kg·m−3. A total of 221 compressed liquid densities of CO2(1) +n-decane(2) mixtures along the five isotherms betweenT= (283 and 363) K with pressures up to 100 MPa were presented. The densities of mixtures were correlated by the modified Tait equation, resulting in absolute average deviations between the experimental and calculated values of 0.028%, 0.013%, 0.017%, 0.044%, and 0.042%. In addition, the isothermal compressibility, isobaric thermal expansivity, and excess molar volume were derived from the modified Tait equation.
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PHYSICA B-CONDENSED MATTER
·
2024
·
IF 2.8
MeiGe Ding,XiHao Gao,Yongchen Sui,Zhenyu Yuan
This study designs to investigate a high-performance n-butanol gas sensor with a porous morphology. Porous ZnO flakes modified with Ag particles are prepared in two steps using hydrothermal and precipitation methods. Morphological analysis of the samples shows that the ZnO flakes were covered with mesopores with high porosity, and their edge lengths ranged from 3 μm to 6 μm, with a minimum thickness of 11.3 nm. Through rigorous gas sensing testing, we find that the optimal mass percentage Ag-ZnO sensor provided significantly better sensing behavior, with a 100.8 response for 100 ppm n-butanol, compared to 14.5 for the pure ZnO sensor, a 5.95-fold improvement. In addition, the sensor's optimal operating temperature is reduced from 290 °C to 190 °C, increasing its adaptability and versatility in practical applications. In subsequent tests, it is found that this Ag-ZnO sensor not only shows excellent selectivity to n-butanol but also favorable stability, with no significant degradation during 30 days of continuous testing. The experimental analysis shows that the formation of porous flake structure and the modification of Ag particles are effective approaches to improve the ZnO gas sensor.
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BIOTECHNOLOGY AND BIOENGINEERING
·
2024
·
IF 3.5
Wentao Yang,Xiao Chen,Li Pang,Hong Tian,Liang Yang,Bo Xia
Glucosamine (GlcN) is a widely utilized amino monosaccharide. It is traditionally synthesized from N -acetylglucosamine (GlcNAc) via chemical processes that pose environmental threats. In pursuit of a greener alternative, our investigation explored biocatalysis with a Pantoea dispersa derived deacetylase (Pd-nagA), showcasing its efficacy as a catalyst in GlcN production. As a result, this work provides a comprehensive characterization of Pd-nagA, scrutinizes its enzymatic behavior, and delves into the deacetylation mechanism in detail. Heterologous expression methods were utilized for the production and isolation of Pd-nagA, followed by a kinetic evaluation highlighting its enzymatic activity. The complex interactions between the enzyme and its substrate were investigated by integrating classical molecular dynamics, quantum mechanics/molecular mechanics simulations, funnel metadynamics, and on-the-fly probability enhanced sampling techniques, thereby elucidating the precise deacetylation pathway. Rigorous computational analysis results demonstrated that Pd-nagA exhibited promising specificity and efficiency for GlcNAc with a high turnover rate. The catalytic residues central to the reaction were identified, and the underlying quantum reaction mechanism was detailed. Our findings suggest an approach to GlcN production using eco-friendly biocatalysis, positioning Pd-nagA at the forefront of industrial application not only because of its remarkable catalytic capabilities but also due to its potential for enzyme optimization.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Xueyun Yang,Jianhao Zhu,Yingli Wang,Jiacun Wang,Yajuan Li,Yuanxiang Gu,Qingliang Lv,Lei Wang
Despite the ultrahigh theoretical energy density and cost-effectiveness, aprotic lithium-oxygen (Li-O 2 ) batteries suffer from slow oxygen redox kinetics at cathodes and large voltage hysteresis. Here, we well-design ultrafine Co nanoparticles supported by N -doped mesoporous hollow carbon nanospindles (Co@HCNs) to serve as efficient electrocatalysts for Li-O 2 battery. Benefiting from strong metal-support interactions, the obtained Co@HCNs manifest high affinity for the LiO 2 intermediate, promoting formation of ultrathin nanosheet-like Li 2 O 2 with low-impedance contact interface on the Co@HCNs cathode surface, which facilitates the reversible decomposition upon charging. The mesoporous hollow nanospindles can provide abundant electron/ions transport channels to synergistically accelerate the formation and decomposition of discharge products. The Li-O 2 battery based on Co@HCNs displays remarkably reduced discharge/charge polarization of 0.92 V, impressive rate performance, and stable operation for 250 cycles. This work will provide a new avenue to design advanced oxygen electrocatalysts for high-performance Li-O 2 battery.
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