Journal of Materials Chemistry B
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2014
·Vol. 2
·期 44
·7756-7764
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IF 0
Jiang Wu,Ying Liu,Wei Li,Chunyan Wang,Yanjun Li,Ying Tian,Jing Sun,Shouju Wang,Xin Wang,Yuxia Tang,Hong Zhu,Zhaogang Teng,Guangming Lu
Small interfering RNA (siRNA) has great potential for gene therapy of breast cancer. The development of multifunctional nanocarriers possessing the targeted ability and multimodal imaging function is important to increase siRNA transfection efficiency and to visualize the delivery events. Herein, we demonstrate flavin mononucleotide (FMN) and polyethylenimine (PEI) modified Fe3O4@mTiO2 nanoparticles (Fe3O4@mTiO2/FMN-PEI) as novel magnetic fluorescent siRNA delivery systems. The system has magnetic targeting, magnetic resonance imaging (MRI), optical imaging, and high siRNA binding ability. Survivin-siRNA delivered by this system can effectively enter into MCF-7 cells, which can be further enhanced by exerting an external magnetic field. More importantly, the siRNA delivery events including the location, trafficking, distribution, and release, can be visualized by MRI and optical imaging. Gene silencing by survivin-siRNA can cause significant protein knockdown (96%) and considerable cell apoptosis (30%), indicating the usefulness of Fe3O4@mTiO2/FMN-PEI as a siRNA delivery system.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2014
·
IF 3.552
Ruixiong Huang,Zhanqiang Fang,Xiaobo Fang,Eric Pokeung Tsang
In this study, Fe 3 O 4 NPs (named as Fe 3 O 4 NPs-PO) were prepared by steel pickling waste liquor to reduce the cost of preparation, and were compared with those obtained by the common co-precipitation method (named as Fe 3 O 4 NPs-CP) which prepared from chemical reagent using BET, XRD, XPS, TEM and SEM techniques. The results indicated that Fe 3 O 4 NPs-PO nanoparticles mainly existed in the form of Fe 3 O 4 and appeared to be roughly spherical in shape with a size range of 20–50 nm. The heterogeneous Fenton-like catalytic capacity of Fe 3 O 4 NPs-PO in US + Fe 3 O 4 + H 2 O 2 system was comprehensively investigated. BPA could be degraded within a wide pH range of 7–10. The removal efficiencies of BPA were close to 100% and about 45% total organic carbon (TOC) in solution was eliminated at the optimized conditions. It was found that· OH radicals which mainly caused the degradation of BPA were promptly generated due to the catalysis of the Fe 3 O 4 NPs-PO. Furthermore, the comparative study of catalytic activity, stability and reusability between Fe 3 O 4 NPs-PO and Fe 3 O 4 NPs-CP showed that the two catalysts both remained good activity after several reaction cycles and no significant change in composition and structure was observed, the loss of catalyst was negligible, which demonstrated that Fe 3 O 4 NPs-PO were promising in ultrasonic Fenton-like process to treat refractory organics.
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高影响因子
WATER RESEARCH
·
2015
·
IF 5.528
Fidèle Suanon,Qian Sun,Daouda Mama,Jiangwei Li,Biaou Dimon,Chang-Ping Yu
Anaerobic digestion (AD) is one of the most widely used processes to stabilize waste sewage sludge and produce biogas renewable energy. In this study, two different iron nanoparticles [nanoscale zero-valent iron (nZVI) and magnetite (Fe 3 O 4 )] were used in the mesophilic AD processes (37 ± 1 °C) to improve biogas production. In addition, changes of heavy metal (Cd, Co, Cu, Zn, Ni and Cr) speciation during AD of sludge with and without iron nanoparticles have been investigated. Concentrations of metals in the initial sludge were as follows: 63.1, 73.4, 1102.2, 2060.3, 483.9 and 604.1 mg kg −1 (dry sludge basis) for Cd, Co, Cu, Zn, Ni and Cr, respectively. Sequential fractionation showed that metals were predominantly bonded to organic matter and carbonates in the initial sludge. Compared with AD without iron nanoparticles, the application of iron nanoparticles (at dose of 0.5% in this study) showed positive impact not only on biogas production, but also on improvement of metals stabilization in the digestate. Metals were found concentrated in Fe–Mn bound and residual fractions and little was accumulated in the liquid digestate and most mobile fractions of solid digestate (water soluble, exchangeable and carbonates bound). Therefore, iron nanoparticles when properly used, could improve not only biogas yield, but also regulate and control the mobilization of metals during AD process. However, our study also observed that iron nanoparticles could promote the immobilization of phosphorus within the sludge during AD, and more research is needed to fully address the mechanism behind this phenomenon and the impact on future phosphorus reuse.
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高影响因子
RSC Advances
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2015
·Vol. 5
·期 25
·19581-19586
·
IF 3.84
Yixin Liu,Tao Yan,Yueyun Li,Wei Cao,Xuehui Pang,Dan Wu,Qin Wei
A simple label-free photoelectrochemical (PEC) platform was developed based on magnetic CdS–Fe3O4 nanocomposites and used for detection of aflatoxin B1 (AFB1). CdS quantum dots (QDs) were successfully assembled on mesoporous Fe3O4 NPs via covalent binding and employed as the photoactive materials on the surface of screen-printed electrode (SPE). H2O2 was employed as a sacrificial electron donor for scavenge photo-generated holes in the valence band of CdS QDs. Anti-aflatoxin B1 (anti-AFB1) was conjugated onto CdS–Fe3O4 nanocomposites modified SPE by using the classic EDC coupling reactions between the carboxy group (–COOH) groups on the surfaces of the TGA capped CdS QDs and the amino group (–NH2) groups of the antibody (Ab). The concentrations of AFB1 were measured through the decreased photocurrent resulting from the increased steric hindrances due to the formation of the immunocomplex. Under the optimal conditions, the PEC biosensor for AFB1 determination exhibited a linear range from 0.01 ng mL−1 to 80 ng mL−1 with a detection limit of 5.0 pg mL−1. Besides, the PEC biosensor has been applied in the corn samples detection. The proposed PEC biosensor is simple, sensitive, fast and stable, which opens up a new promising PEC platform for other small molecules analysis.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2015
·
IF 2.999
Yanqin Yang,Mengmeng Kang,Shaoming Fang,Minghua Wang,Linghao He,Xiaozhong Feng,Jihong Zhao,Zhihong Zhang,Hongzhong Zhang
It is highly desirable and a popular topic in scientific research to develop a highly sensitive and selective detection and quantitative analysis method of determining trace silver ions (Ag + ) in aqueous media since Ag + ions are recognized as one of the most hazardous metal pollutants. Three-dimensional graphene oxide (3D-GO) was decorated with Fe 3 O 4 to form nanocomposites of Fe 3 O 4 @3D-GO, which were further used as electrode materials in an electrochemical DNA sensor for detecting Ag + . Because of the chemical functionality and porous structure of the developed nanocomposites, single-stranded and cytosine-rich oligonucleotides could be anchored onto their surfaces or interior, followed by selective detection of Ag + through formation of C–Ag + –C complex forms. The results of electrochemical measurement showed that the Fe 3 O 4 @3D-GO nanocomposites exhibits high sensitivity for detecting Ag + with a detection limit of 2.0 pM within the range of 0.01–100 nM Ag + (S/N = 3). The developed electrochemical biosensor based on Fe 3 O 4 @3D-GO exhibits highly selectivity, good repeatability, and stability for detecting Ag + ions. The results of this work demonstrate that Fe 3 O 4 @3D-GO nanocomposites could be used as a promising tool to detect heavy metal ions in water or the environment.
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高影响因子
RSC Advances
·
2015
·Vol. 5
·期 124
·102610-102618
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IF 3.84
Yufeng Shan,Yong Yang,Yanqin Cao,Zhengren Huang
Nanocomposites of noble metal and magnetic materials deliver both SERS activity and magnetic properties, and thereby have great advantages for trace analysis in the fields of analytical chemistry, biological and environmental sciences. In this work, Ag/Fe3O4 nanocomposites have been obtained by a facile one-pot solvothermal method. The Fe3O4 nanoparticles (NPs) compounded with Ag possess excellent superparamagnetism, which guarantees an effective self-aggregation of the Ag/Fe3O4 composites. The saturation magnetic moment and SERS activity of the as-prepared nanocomposites are easily optimized by adjusting the mole ratio of silver oleate and iron oleate. The sample with Ag/Fe = 5 possesses optimal SERS performance for both R6G and MB detection. The Fe3O4 NPs with ultra small size behave just like glue or a contractile net, which wrap the Ag NPs together under an external magnetic field and give rise to high-density and high-intensity “hot-spots”. The enhancement factors (EFs) of the sample with Ag/Fe = 5 are over ∼108 both for R6G and MB detection. The as-prepared magnetic nanocomposites have been applied to realize an efficient but convenient real-time on-line monitoring of atrazine in flowing pesticide contaminated water, which show enormous potential in the application of on-line monitoring for industrial and agricultural production.
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JOURNAL OF MATERIALS SCIENCE
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2015
·Vol. 51
·期 6
·3170-3181
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IF 2.371
Wen Xin,Qiao Xianliang,Han Xue,Niu Libo,Huo Li,Bai Guoyi
Abstract A series of novel magnetic branched polyethylenimine nanogels (Fe 3 O 4 /bPEI) was prepared via the combination of crosslinking branched polyethylenimine to form a nanogel and in-situ generation of Fe 3 O 4 on its surface. Morphologies and magnetic properties of the Fe 3 O 4 /bPEI nanocomposites could be easily controlled by regulating the ratio between branched polyethylenimine nanogel and Fe 3 O 4 precursor. The nanocomposites could be applied as efficient and selective dye adsorbents for the removal of Congo red under different pH values or in the presence of methylene blue. Furthermore, it could also be applied as catalyst support for the loading of palladium to afford a novel Pd-Fe 3 O 4 /bPEI nanocomposite, which exhibited good catalytic activity in the reduction of nitrophenols using NaBH 4 as the reducing agent. Particularly, this nanocomposite could be easily separated by an external magnetic field and recycled ten times without appreciable loss of its initial catalytic activity. The synergistic integration of nanogel and magnetic Fe 3 O 4 nanoparticles makes Fe 3 O 4 /bPEI to be a versatile platform for multiple applications. Graphical Abstract Magnetically recyclable polyethylenimine nanogels (Fe 3 O 4 /bPEI), prepared with in-situ generated Fe 3 O 4 , can serve as excellent dye adsorbent and catalyst support.
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RSC Advances
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2015
·Vol. 6
·期 1
·481-488
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IF 3.84
Jinna Wang,Guanhong Xu,Fangdi Wei,Jing Yang,Ping Zhou,Qin Hu
A novel fluorescence method was established for detecting sialic acid (SA) by using phenylboronic acid (PBA)-functionalized Fe3O4/CdTe magnetic nanoparticles as fluorescence probe. Initially, Fe3O4 nanoparticles were modified with amino groups, and then 3-mercapto propionic acid-stabilized CdTe quantum dots (QDs) were covalently linked to the amino-modified Fe3O4 nanoparticles to form Fe3O4/CdTe magnetic fluorescence nanoparticles. Finally, PBA was introduced on the surface of Fe3O4/CdTe to form PBA-functionalized Fe3O4/CdTe magnetic fluorescence nanoparticles. This kind of nanoparticle can specifically recognize SA and its fluorescence intensity is quenched by SA. In addition, the conjugate of the nanoparticles and SA is easy to separate from the sample matrix due to its magnetic properties. Therefore, this nanoparticle can be used as a fluorescence probe to detect SA. Under optimal conditions, the fluorescence intensity of the nano probe was found to be inversely linear with the concentration of SA in a wide range of 50 μg ml−1–1.50 mg ml−1, and the limit of detection was 16 μg ml−1. The PBA-functionalized Fe3O4/CdTe nano probe was applied to the determination of SA in infant formula, and the result showed high accuracy and precision. The PBA-functionalized Fe3O4/CdTe nano probe has the potential to be used to monitor SA in food.
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高影响因子
NEW JOURNAL OF CHEMISTRY
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2014
·Vol. 38
·期 8
·3999-4006
·
IF 3.159
Zhenzhen Wang,Shangru Zhai,Bin Zhai,Zuoyi Xiao,Feng Zhang,Qingda An
Novel protocol towards multifunctional magnetic organic–inorganic core–shell nanostructured catalysts of Fe3O4@SN/HPW@CG–Ag with tailored properties are presented in this work. Such nanocomposites congregate the properties and functions of a single component into a whole. For instance, Fe3O4 cores protected by amino-functionalized SiO2 shell endowed the composites with superparamagnetism (28.6 emu g−1) and thereby facilitate the process of separation and recovery. Phosphotungstic acid, as a bridging agent, provided a strong interaction for the anchoring of glutaraldehyde cross-linked chitosan onto the surface of Fe3O4@SN. More interestingly, chitosan could simultaneously behave as a stabilizer and reductant for the in situ synthesis of “green” Ag NPs without addition of any other reducing agent or organic solvent, and Ag NPs provided the compounds with a catalytic performance. Further the size, loading of Ag NPs and the thickness of the chitosan layer were all controllable. Meaningfully, the as-synthesized catalyst Fe3O4@SN/HPW@CG–Ag exhibited an exceptional catalytic performance for the reduction of 4-nitrophenol in the presence of sodium borohydride (the reaction was accomplished within 7 min) and could be reused at least 10 times with good stability by means of convenient magnetic separation. Thence, the design philosophy of the multifunctional robust Ag-based nanocatalysts may pave the way for the synthesis of other catalyst systems with long-term stability.
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高影响因子
TALANTA
·
2017
·
IF 4.162
Qi Wang,Qian Zhou,Qicheng Zhang,Rongjia Shi,Shangshang Ma,Wenbo Zhao,Min Zhou
Preparation of high performance electrochemical biosensing interface for the sensitive and rapid detection of human metabolites is of great interest for health care and biomedical science. In this paper, based on the adhesion technique of marine mussels, we designed and prepared a novel biosensor with a micro/nano-biointerface of Fe 3 O 4 -Mn 3 (PO 3 ) 2 @Ni foam, which offered a three dimensional (3D) living environment for real cell. The constructed biosensor with a 3D micro/nano-biointerface of Fe 3 O 4 -Mn 3 (PO 3 ) 2 @Ni foam was characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and elemental mapping. Furthermore, the electrochemical experiments by electrochemical method for detection of superoxide anion (O 2 •− ) in situ released by cells were carried out by this biosensor we proposed. Results indicated that the 3D interface of mussel-inspired Fe 3 O 4 -Mn 3 (PO 3 ) 2 @Ni foam offered an amicable platform for promoting cell adhesion, which was beneficial for enhancing biosensing activity. This proposed sensing platform provided high electroactivity and excellent electron transport with a lower detection limit (0.0170 μM), wider linear range 0.04–2.44 μM) and short diffusion distance to reaction sites. The case achieved the accurate detection of O 2 •− (in situ released by cells) based on the combination of mussel-inspired biomimetic adhesion technique, 3D micro/nano-biointerface construction and electrochemical biosensing technique.
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高影响因子
RSC Advances
·
2017
·Vol. 7
·期 72
·45545-45551
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IF 3.108
Shili Liu,Aori Qileng,Junying Huang,Qiongzhi Gao,Yingju Liu
Herein, gold nanoparticles (Au NPs) were decorated on magnetic Fe3O4 nanoclusters@polydopamine nanocomposites (Fe3O4@PDA NCs) through a direct and green reduction method. The morphology was investigated via transmission electronic microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). Results showed that Fe3O4 nanoclusters were successfully coated with a PDA shell layer of 25 nm thickness that could work as a reducing reagent to form Au NPs on the surface of Fe3O4@PDA NCs and prevent the aggregation of Au NPs as well. More interestingly, the concentration of the Au precursor had a great effect on both the size and the dispersion of Au NPs on the surface of Fe3O4@PDA NCs, which directly affected the catalytic activity of Fe3O4@PDA@Au. The catalytic performance of Fe3O4@PDA@Au was determined by reducing 4-nitrophenol to 4-aminophenol in the presence of excessive NaBH4, and the result showed that Fe3O4@PDA@Au prepared from a 130 μM Au precursor exhibited the best catalytic activity with the reaction rate constant of 39.2 s−1 g−1 and a conversion of >99% in ten minutes. After being recycled and reused ten times, the magnetic catalyst still had a conversion of >95%; this suggested that it might have practical applications in the reduction of nitroaromatic compounds.
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JOURNAL OF APPLIED POLYMER SCIENCE
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2016
·Vol. 133
·期 20
·
IF 1.866
Caihong Wang,Hao Wu,Fangshu Qu,Heng Liang,Xiaojun Niu,Guibai Li
To investigate the influence of magnetic materials combined with carbon nanotubes (CNTs) as fillers on the membrane properties, multi-walled carbon nanotubes (MWCNTs) functionalized by mixed acids (V H2SO4 :V HNO3 =3:1) were loaded by Fe 3 O 4 through a hydrothermal method. The obtained MWCNTs/Fe 3 O 4 hybrids were characterized by X-ray diffraction (XRD), Infrared spectroscopy (IR) spectrum, and scanning electron microscope (SEM) and then blended with polyvinyl chloride (PVC) to prepare ultrafiltration (UF) membranes through a phase inversion process. Simultaneously, two other UF membranes, PVC blended with acid-treated MWCNTs and PVC blended with nothing, were also prepared. The results showed that the membrane porosity and mean pore size increased slightly with the addition of fillers. Static contact angle showed that MWCNTs/Fe 3 O 4 hybrids improved the hydrophilicity of membrane surface better than the acid-treated MWCNTs. Pure water flux increased consistently with the hydrophilicity of the membrane surface. SEM and atomic force microscope (AFM) images showed that the MWCNTs/Fe 3 O 4 blended membrane formed a relatively complete pore structure throughout the cross-section and had a rougher top surface. However, the mechanical properties of membranes with fillers were reduced compared with the pristine PVC membrane. The rejections of membranes for Bovine serum albumin (BSA), Bisphenol A (BPA), and Norfloxacin (NOR) showed that MWCNTs/Fe 3 O 4 played an important role in trapping pollutants in membrane filtration. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43417.
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