Green Energy & Environment
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2020
·
IF 6.395
Jiake Wang,Yan Wang,Zhongzheng Ma,Lifeng Yan
Green solvents for cellulose dissolution is a key topic for green chemistry, especially natural cellulose with high molecular weight, and there are scarce solvents reported. Deep eutectic solvent (DES) is a typical kind of green solvent that has been attracted much attention recently. Here, high molecular weight natural cellulose (DP > 3000) was first isolated from wheat straw and then be directly dissolved in the choline/ l -lysine (Ch/Lys) DES. The solution owns excellent stability, and the solubility reaches ∼5%. Rheological studies revealed that the natural cellulose can be well dispersed in the DES solution and showed gelation at high concentrations. The dissolved cellulose can be regenerated when the dilute acid aqueous solution was added into the solution. It provides an energy conversation and an environmentally friendly route to prepare a cellulose solution, which makes it possible to convert cellulose to valuable chemicals and materials in its homogeneous solution.
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高影响因子
ENERGY & FUELS
·
2017
·
IF 3.091
Zi-zhe Cai,Sheng-qing Wu,Guo Sun,Yi Niu,Dong Zheng,Shi-yi Peng,Wen-zhe Yang,Yong Wang,Depo Yang
With the cost of traditional lipid feedstocks constituting 70% of the total cost of biolubricant production, it is urgent to find a new lipid source for the biodiesel and biolubricant industry. With the elevated acid value (61.8 mg of KOH/g) of housefly larval lipids, converting the free fatty acid (FFA) into a biolubricant could serve as a value-added approach to the larval diesel industry, other than pretreatment by acid-catalyzed esterification for biodiesel production. This study developed a method of producing high-purity fatty acid n-octyl esters (FAOEs) from housefly (Musca domestica L.) larvae. The housefly larva free fatty acids (HLFFAs) from the larva lipids were obtained by wipe-film short-path distillation. FAOEs were produced by esterifying n-octanol with HLFFAs (catalyzed by benzenesulfonic acid under the following conditions: catalyst loading, 2 wt %; molar ratio of n-octanol to FFA, 3:1; temperature, 100 °C; time, 2 h). Excess n-octanol was effectively removed by high-vacuum (80 Pa) distillation at 90 °C. The unreacted FFAs were neutralized using demethylated crude glycerin, which is a byproduct of biodiesel production. A practical method of producing high-purity fatty acid n-octyl esters (99.19 wt %) derived from housefly larva lipids was thus developed, and the product could serve as a replacement for certain low-viscosity mineral lubricants such as liquid paraffin, polyalphaolefin 6, and SN 500.
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APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Wan-Jie Si,Li Yang,Jiang Zhu,Yi-dong Li,Jian-Bing Zeng
Three biodegradable elastomers with different chemical structures , i.e., polyurethane (PU), poly( l -lactide)-b-polyurethane-b-poly( l -lactide) (LPUL) and poly( d -lactide)-b-polyurethane-b-poly( d -lactide) (DPUD) triblock copolymers were prepared to blend with commercial poly( l -lactide) (PLLA) to provide weak, medium and strong interfacial interactions through weak van der Walls, interfacial chain entanglement and interfacial stereocomplex (SC) crystallization, respectively. Morphology analysis indicated that the size of dispersed phase in the amorphous PLLA matrix decreased with increasing PLLA or PDLA content of the biodegradable elastomers and agglomeration of dispersed particles occurred obviously during matrix crystallization for PLLA/PU and PLLA/LPUL blends due to the relatively weak interfacial interactions, while agglomeration did not occur apparently for PLLA/DPUD blends due to the strong interfacial interaction arisen from the interfacial SC crystallites . With well-tuned and stabilized phase morphology, PLLA/DPUD exhibited the best toughening efficiency for both the amorphous and highly crystalline PLLA matrix. Moreover, the PLLA/DPUD showed the highest mechanical strength and crystallization rate, attributing to the presence of interfacial SC crystallites , which could reinforce the mechanical strength and work as efficient nucleating agents for crystallization of PLLA matrix. In addition, PLLA/DPUD blends showed superior heat resistance over PLLA/PU and PLLA/LPUL blends by processing on conventional machine. All the excellent performances were attributed to the special interfacial interaction originated from interfacial SC crystallites of PLLA/DPUD blends.
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高影响因子
ORGANIC PROCESS RESEARCH & DEVELOPMENT
·
2024
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IF 3.1
Chuanjun Wu,Heng Guo,Jiawei Tang,Lintao Xia,Jianfen Shao,Yongfu He,Fei Chen,Peng Peng,Yuewen Han,Chuanmeng Zhao,Fuli Zhang,Shaoxin Chen
In the present study, a practical chemoenzymatic method was developed for the synthesis of chiral phenylalanine derivative 1, which is the key intermediate of Lifitegrast. In this established process, a simple and effective Zn/HCl reduction system was employed to obtain N-acetyl-3-bromo-phenylalanine 6, which served as the substrate for the subsequent enzymatic resolution process. Then, the key chiral intermediate, 3-bromo-l-phenylalanine 7, could be obtained using acylase (ACY) AmACY. Upon process optimization, the chemical reaction was executed at a 300 g scale, with a notable substrate concentration reaching up to 100 g/L. The process achieved a yield of 40%, compared to a maximum theoretical yield of 50%, and exhibited an enantiomeric excess (ee) value reaching up to 99.9%. A simple and effective Zn/HCl reduction system was employed to obtain N-acetyl-3-bromo-phenylalanine 6, which served as the substrate for the subsequent enzymatic resolution process. This synthetic pathway was effectively executed, yielding 1·HCl with a purity of 99.7% and an ee value of 99.9%, culminating in an overall yield of 23.4%. Additionally, the undesired (D)-6 enantiomer was recycled to form (rac)-6, employing an acetanhydride/acetic acid (Ac2O/AcOH) system. This recycling process achieved a yield of 47.5%, relative to a maximum theoretical yield of 50%, and a purity level of 99.8%.
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MICROCHEMICAL JOURNAL
·
2025
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IF 5.1
Qingfen Zhang,Chenglin Li,Shengcheng Mi,Xiaojie Xu,Zhiqiang He,Lin Wang,Zhonghua Tang,Qi Lu
The primary purpose of this study is to develop a highly efficient extraction method to meet the growing demand for Kaempferia galanga essential oil (KGEO) in various industries. In this study, an innovative approach for extracting essential oil from fresh K. galanga rhizomes using salt solution-enhanced homogenization pretreatment and microwave extraction (HP-SOME) was proposed. A kinetic study was conducted on the extraction process of essential oil. The key factors were screened using the Plackett–Burman Design and optimized using the Box-Behnken Design. Under the optimization parameters: sodium chloride concentration of 1.5 %, microwave power of 475 W, and microwave time of 23 min, the actual yield was 5.26 ± 0.10 %. The HP-SOME method exhibited a significant increase of 58.91 % in essential oil yield compared to that of the hydrodistillation method (3.31 ± 0.10 %). In addition, the composition of the KGEO was determined using Fourier transform infrared spectroscopy, Raman spectroscopy, and gas chromatography-mass spectrometry. The KGEO obtained by HP-SOME had a 6.26 % increase in the main component ethyl p-methoxycinnamate and a 4.13 % increase in ethyl cinnamate compared to that obtained by the HD method. Investigations into antimicrobial activity revealed that KGEO extracted by the HP-SOME method exhibited superior and more comprehensive antimicrobial characteristics. In conclusion, the HP-SOME method demonstrated remarkable capabilities in obtaining KGEO with notable efficiency, yield, and quality. This method holds great promise in the field of essential oil extraction.
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产品关联
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2018
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IF 2.88
Shi-Ting Zhang,Panpan Li,Caiyun Liao,Tingting Luo,Xingming Kou,Dan Xiao
A ruthenium(II) bipyridyl complex conjugated with functionalized Schiff base (RuA) has been synthesized and functioned as a luminescent probe. The luminescence of RuA was greatly quenched by Cu 2+ due to its molecular coordination with paramagnetic Cu 2+ . Subsequently, the addition of l -Histidine can turn on the luminescence of the RuA-Cu(II) ensemble, which can be attributed to the replacement of RuA in RuA-Cu(II) ensemble by l -Histidine. On the basis of the quenching and recovery of the luminescence of RuA, we proposed a rapid and highly sensitive on-off-on luminescent assay for sensing Cu 2+ and l -Histidine in aqueous solution. Under the optimal conditions, Cu 2+ and l -Histidine can be detected in the concentration range of 5 nM–9.0 μM and 50 nM–30 μM, respectively, and the corresponding detection limits were calculated to be 0.35 and 0.44 nM (S/N=3), separately. The proposed luminescent probe has been successfully utilized for the analysis of Cu 2+ and l -Histidine in real samples (drinking water and biological fluids). Furthermore, the probe revealed good photostability, low cytotoxicity and excellent permeability, making it a suitable candidate for cell imaging and labeling in vitro.
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产品关联
DOI
PubMed
高影响因子
MEDICINAL CHEMISTRY RESEARCH
·
2025
·
IF 3.1
Rong Zhenji,Yu Chunping,Wang Xin,Wang Ruyue,Gao Yang,Zhang Hailong
Blue honeyberry is a well-known nutritious fruit. Meanwhile, it is also an Oroqen herb in China. However, the chemical constituent of the leaves of the plant is little known, despite having better anti-inflammatory activity. In this study, we investigated the chemical constituents of blue honeyberry leaves and screened their anti-inflammatory effects in RAW264.7 cells. Thirty-nine compounds including a new fernane-type triterpenoid were isolated and identified using various chromatographic approaches and spectroscopic techniques. The new compound and some other components showed a significant anti-inflammatory effect by inhibiting nitric oxide production in RAW264.7 cells, in which compounds 6 and 38 exhibited the inhibition of 40.6 ± 4.8% and 46.0 ± 1.4% at the concentration of 100 μM, respectively, without inducing any cytotoxicity.
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高影响因子
CELLULOSE
·
2025
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IF 4.8
Zhang Yutian,Zeng Dongdong,Li Jianing,Ma Xiaojun,Li Dongna,Li Yachao
Co-substrate fermentation has become an essential approach to achieving high-efficiency and low-cost production of poly (β- l -malic acid) (PMA). Herein, sustainable rubberwood ( Hevea brasiliensis ) hydrolysate (RWH) was co-fermented by A. pullulans to synthesize PMA using glucose and xylose as co-substrate carbon sources. Moreover, vitamin B was explored as nutrient supplementation in this study. Results showed that compared with the single RWH substrate, the PMA production of co-substrate fermentation increased by 38–52%. Furthermore, the addition of VB 6 promoted the utilization of substrates and shortened the fermentation cycle of PMA. During the scale-up fermentation, the PMA yield reached 0.50–0.54 g/g. Compared with traditional glucose culture medium, co-substrate fermentation improved the conversion rate of carbon sources and reduced PMA production cost by 14.9–36.6%. This work provides a new path for high-efficiency and economical industrial fermentation technology of PMA.
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DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Huakuo Zhou,Peng Li,Yifei Li,Yi Ke,Xia Zhang,Jun Meng
In recent years, most of the studies on nanozymes have focused on improving their catalytic activity and direct synthesis, but this task is still very complex. Bimetallic oxides are particularly popular due to their mixed valence and synergistic effects between different metal ions. In this study, Fe-Mn bimetallic oxide nano-cubes were prepared by fast and effective solvothermal synthesis, and nano-flower-like structures were grown on the surface of Fe-Mn oxide nanocubes via controlled etching. The synthesized Fe-Mn bimetallic oxide nano-flowers (FMBO NFs) have great oxidase-like activity. On this basis, a simple, economical and accurate colorimetric sensor was established by combining 3,3',5,5'-tetramethylbenzidine (TMB). Exposure to L-cysteine (L-Cys) inhibited the catalytic activity of FMBO NFs. As the concentration of L-Cys increased, the absorbance at 652 nm decreased, with a good linear relationship in the range of 0.01-1000 μM, with a limit of detection (LOD) of 3.99 × 10 -11 M, and the detection of L-Cys in the actual sample egg yolk was successfully achieved. This study provides theoretical support for the effective design of bimetallic oxide nanozyme activity, and can guide the development of an accurate detection system for the analysis of L-Cys in food.
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高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2023
·Vol. 24
·期 1
·782
·
IF 5.6
Yue Chen,Xinru Hou,Yupin Zheng,Yingmin Lyu
Lily (Liliumspp.) has elegant flowers and beautiful colors, which makes it popular among people. However, the poor stress resistance and self-propagation ability of lily limit its application in landscaping to a great extent. In addition, transgenic technology is an important means to improve plant characteristics, but the lack of a stable and efficient genetic transformation system is still an important factor restricting the development of lily transgenic technology. Therefore, this study established a good lily regeneration system by screening different explants and plant growth regulators of different concentrations. Then, the genetic transformation system of lily was optimized by screening the critical concentration of antibiotics, the concentration of bacterial solution, and the infection time. Finally, the homologous lily cold resistance geneLlNAC2and bulblet generation geneLaKNOX1were successfully transferred to ‘Siberia’ and ‘Sorbonne’ to obtain lily transgenic lines. The results showed that when the stem axis was used as explant in ‘Siberia’, the induction rate was as high as 87%. The induction rate of ‘Sorbonne’ was as high as 91.7% when the filaments were used as explants. At the same time, in the optimized genetic transformation system, the transformation rate of ‘Siberia’ and ‘Sorbonne’ was up to 60%. In conclusion, this study provides the theoretical basis and technical support for improving the resistance and reproductive ability of Oriental lily and the molecular breeding of lily.Keywords:embryogenic callus;sterile scales;establishment of regeneration system;optimization of genetic transformation system;homologous transformation
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PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
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2018
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IF 5.08
Wufeng Yang,Keke Wu,Xiaoyan Liu,Yanpeng Jiao,Changren Zhou
In this study, a poly l -lactic acid (PLLA) fibrous mat was prepared by electrospinning, followed by surface modification with polydopamine (PDA), based on its strong adhesion performance and self-polymerization of dopamine. The PDA coating on the fibrous mat surface provided a reaction platform for heparin via a Michael-type addition reaction and a reductive surface for Ag + in situ formation of silver nanoparticles (AgNPs) in AgNO 3 solution. The structure and chemical composition of the fibrous mats were determined by scanning electronic microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. All the results confirmed the successful immobilization of heparin and AgNPs on the PLLA fibrous mats. Thermogravimetric analysis (TGA) and energy dispersive X-ray spectrum (EDS) analysis were used to determine the content of AgNPs and their distribution on the fibrous mat surface. Water contact angle measurements showed the hydrophilic improvement after modification. The antibacterial investigation indicated that the fibrous mats could inhibit the growth of both Escherichia coli ( E . coli ) and Staphylococcus aureus ( S . aureus ). Protein adsorption, the hemolysis test, the coagulation test, complement activation, and platelet activation were used to confirm the compatibility with blood and the anticoagulation property of the fibrous mats. Finally, cell proliferation and live/dead assays, conducted with cultured fibroblasts on the fibrous mats, showed that the modified fibrous mat surface had good cell compatibility. This antibacterial/anticoagulant dual-functional surface, based on poly l -lactic acid electrospun fibrous mats, would have potential application in blood contacting materials.
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2022
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IF 7.139
Shuang Liang,Guozhe Sui,Jinlong Li,Dongxuan Guo,Ze Luo,Rongping Xu,Hong Yao,Chao Wang,Shijie Chen
This study presents a novel approach for synthesizing C–ZnO/CdS graded nanorods derived from metal–organic frameworks (MOFs) that can be applied as a catalyst for photocatalytic hydrogen evolution from pure water. Porous C-doped ZnO was prepared by a self-template method using imidazole-like metal–organic backbone (ZIF-L) as a precursor through a two-step calcination method. CdS nanoparticles were deposited on ZIF-L surface by chemical deposition . The two-step calcination method introduced elemental C, and the unique architecture of ZIF-L played an essential role in forming the hierarchical structure of the porous ZnO nanorods. Compared with other ZnO/CdS catalysts, the C-doped ZnO/CdS graded nanorods exhibited remarkable photocatalytic activity for hydrogen production . The highest hydrogen production rate of 20.25 mmol g −1 h −1 with an apparent quantum yield (AQY) of 24.7% at 365 nm obtained over C–ZnO/CdS with Pt as co-catalyst, which was 24.4 and 65.3 times higher than that over CdS (0.83 mmol g −1 h −1 ) and ZnO (0.31 mmol g −1 h −1 ), respectively. This outcome was attributed to (i) the formation of Z-scheme heterojunction that significantly promoted the separation and migration of photogenerated electron–hole pairs; (ii) C doping that reduced the bandgap of ZnO and broadened its spectral response range; and (iii) the ordered arrangement of porous nanorods that effectively reduced the recombination rate of the electron–hole pairs.
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危险品化学品经营许可证（带存储）