FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Jiaxin Chen,Junjie He,Zihan Zhao,Xin Li,Jie Tang,Qian Liu,Hui Wang
This work aimed to investigate the effects of heat treatments at different temperatures (60, 70 and 90 °C, expressed as HT-60, HT-70 and HT-90) on interfacial composition and protein-lipid co-oxidation in whey protein isolate (WPI)-stabilised O/W emulsions during storage. Compared with control group, all heated emulsions exhibited weaker physical stability over 10 days of storage, which verified by the increased droplet size, as well as decreased adsorbed protein levels and absolute ζ-potential values. Moreover, proteins recovered from the HT-90 emulsion showed the highest fluorescence intensity and red-shift of the maximum emission wavelength, indicating partial unfolding of the protein structure. Meanwhile, severe changes in protein structure were also observed in the HT-70 and HT-90 emulsions, which clearly verified by the degradation of bovine serum albumin, α-lactalbumin and β-lactoglobulin. Furthermore, HT-70 and HT-90 emulsions showed lower levels of lipid hydroperoxides and thiobarbituric acid reactive substances. In contrast, the recovered proteins were subject to severe oxidative stress as indicated by carbonyl and N’-formyl-L-kynurenine. Hierarchical cluster and correlation analysis implied that the process of protein-lipid co-oxidation is inevitable, but it can be retarded by heat treatment. Our results clearly revealed the relevance among heat treatment, interfacial adsorption property, and the protein-lipid co-oxidation of O/W emulsions.
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高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Jiliang Ma,Junqiang Zhang,Dongnv Jin,Shuangquan Yao,Runcang Sun
Synchronous photocatalytic water splitting and the reforming of a biomass-derived feedstock to generate hydrogen and high-value-added chemicals make full utilization of the biomass-water-splitting redox reaction; however, limited successes in this regard have been reported. Herein, incompletely polymerized graphitic carbon nitride co-doped with zinc/oxygen atoms (Zn 2 /O@IP- g -CN) was prepared via a step-by-step low-temperature calcination process with the assistance of melamine and zinc phthalocyanine, which successfully resulted in simultaneous photocatalytic water splitting and the reforming of biomass-derived monosaccharides to produce hydrogen (11436.7 μmol g −1 h −1 ) and lactic acid (92.6 %), respectively. Zn 2 /O@IP- g -CN exhibits a fast separation/migration rate and low resistance compared to those of pure CN, resulting in Zn 2 /O@IP- g -CN showing enhanced photocatalytic activity. The hydrogen release rate of 86.8 % and lactic acid yield of 89.0 % were retained compared to initial values when Zn 2 /O@IP- g -CN was reused in 5 th cycles. Poisoning experiments indicated that 1 O 2 , ·O 2 - , ·OH, and h + were all beneficial for lactic acid production.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Ming Nie,Lu Wang,Shengmin Lu,Yangguang Wang,Meiyu Zheng,Zhongxiang Fang
The protective effects of three amino acids ( l -phenylalanine, l -tryptophan and l -methionine) on the stability of bayberry anthocyanins were investigated. The anthocyanin stability under constant illumination (5000 Lux, 50 Hz) or in the presence of ascorbic acid were evaluated by degradation kinetic parameters, and the interaction between l -methionine and cyanidin-3-O-glucoside (C3G) in a model beverage system was analyzed using Fourier transform infrared spectroscopy, 1H nuclear magnetic resonance, X-ray diffraction, molecular docking, and molecular dynamics simulation. Results indicated that the three amino acids significantly reduced the degradation rate of bayberry anthocyanins (p < 0.05), with the most effect by l -methionine. l -methionine could bind to C3G via hydrogen bonds and Van der Waals forces. This study suggested that l -methionine could well protect anthocyanin against degradation in the aqueous solution and have the potential to be used as a co-pigment to improve the sensory property and extend the shelf life of anthocyanin rich berry products.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Hao Zhang,Yunxiong Zeng,Xinqing Wang,Xingyu Zhan,Jingcai Xu,Ao Jin,Bo Hong
The fast recombination of electron-hole pairs results in low photoactivity, limiting carbon nitride further application in wastewater purification. To address this issue, regulation of electron configuration via optimizing surface atom properties is a promising strategy for improving the separation of electron-hole pairs. Here, sea-urchin carbon nitride (SUCN-6) with C-v and O-s mediated electronic structures were facile prepared, endowing it with a decrease in transportation resistance of charge carriers and increased activation towards oxygen. Under visible light, the SUCN-6 showed a removal efficiency of ∼ 89% towards tetracycline (TC) in 20 min and no obvious decaying after five consecutive cycles. This TC photodegradation follows a first-order kinetic, and its kinetic constant reaches 0.0908 min −1 , which is 2.35 folds higher than that of pristine carbon nitride. In addition, several crucial factors of practical wastewater purification (such as pH, TC concentration, water sources, inorganic salts, and organic matters) that might affect photoactivity were investigated. Moreover, the degradation pathways of TC and intermediates were detected by an HPLC-MS and electron spin resonance instrument, and a possible photodegradation mechanism over SUCN-6 was elucidated. This study offers new insights into the photocatalysis kinetics and photodegradation mechanism over carbon nitride for environmental remediation.
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RENEWABLE ENERGY
·
2022
·
IF 8.634
Chao Yuwen,Bingguo Liu,Qian Rong,Libo Zhang,Shenghui Guo
The continuous spread of COVID-19 has produced a large number of abandoned disposable medical masks (DMMs), which have a greater negative impact on the environment and biosafety. In response to this issue, a method for rapid microwave sulfonation , nitrification and oxidation of DMMs was proposed to convert DMMs with low carbonization efficiency into aromatic carbon with good thermal stability , which not only maintained 51 wt% of initial mass at 1000 °C, but also achieved in situ co-doping of S, N and O. Subsequently, porous carbons derived from DMMs were synthesized by self-activation pyrolysis , which avoided consumption of alkali and metal salts in the traditional activation process . It was further found that low pyrolysis temperature was not enough to produce enough active material H 2 and H 2 O to obtain high specific surface area, while increasing pyrolysis temperature could adjust the specific surface area of as-prepared carbon, ranging from 52 m 2 ·g −1 to as high as 890 m 2 g −1 . Thanks to synergistic effect of S, N, and O co-doping and hierarchical porous structure , the first discharge specific capacity of sample synthesized by self-activated pyrolysis at 900 °C was 1459.8 mAh·g −1 at 0.1 C, and the discharge specific capacity retention at 0.5 C after 400 cycles was 52.3%.
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JOURNAL OF MEDICINAL CHEMISTRY
·
2021
·
IF 7.446
Yiqiang OuYang,Jian Gao,Lei Zhao,Junfeng Lu,Haiqing Zhong,Hua Tang,Shuanglong Jin,Lu Yue,Yuezhen Li,Wenjie Guo,Qiang Xu,Yisheng Lai
Two series of novel o-(biphenyl-3-ylmethoxy)nitrophenyl compounds (A1–31 and B1–17) were designed as programmed cell death protein 1 (PD-1)/PD-ligand 1 (PD-L1) inhibitors. All compounds showed significant inhibitory activity with IC50 values ranging from 2.7 to 87.4 nM except compound A17, and compound B2 displayed the best activity. Further experiments showed that B2 bound to the PD-L1 protein without obvious toxicity in Lewis lung carcinoma (LLC) cells. Furthermore, B2 significantly promoted interferon-gamma secretion in a dose-dependent manner in vitro and in vivo. Especially, B2 exhibited potent in vivo anticancer efficacy in an LLC-bearing allograft mouse model at a low dose of 5 mg/kg, which was more active than BMS-1018 (tumor growth inhibition rate: 48.5% vs 17.8%). A panel of immunohistochemistry and flow cytometry assays demonstrated that B2 effectively counteracted PD-1-induced immunosuppression in the tumor microenvironment, thereby triggering antitumor immunity. These results indicate that B2 is a promising PD-1/PD-L1 inhibitor worthy of further development.
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APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Yao Deng,Yanmei Li,Jing Wang,Huidi Zhang,Lin Wang,Qiong Wang,Tao Xu,Wenlei Wang
Nitrogen deficient porous nanosheets(NDCN) are a promising nano template that can combine defect engineering with Mn-FeOOH to suppress photo generated carrier complexation and optimize electron distribution . In this study, a unique structure with N/O double vacancies in Mn-FeOOH@NDCN was prepared using a magnesium thermal denitrification co-precipitation method. Furthermore, a series of Mn-FeOOH/NDCN/PMS reaction systems were constructed by adjusting the dosage of peroxymonosulfate(PMS). The experimental results indicate that the synergistic activation of N/O double vacancies on PMS enables the Mn-FeOOH/NDCN/PMS system to oxidize almost 10 mg/L of As(III) within 90 min. At the same time, the oxidized As(V) was completely adsorbed, thereby completely removing the total arsenic in the water. The reasonable construction of carbon networks is a prerequisite for the stability of Mn-FeOOH/NDCN composite catalysts, enabling them to have good cyclic stability. The experimental results confirm that oxygen vacancies directly participate in the activation of PMS, while nitrogen vacancies effectively adsorb As(III), thereby promoting the contact between As(III) and PMS, improving the mass transfer rate, and accelerating the catalytic degradation process. This study will provide a new way to completely remove arsenic pollution from water bodies.
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METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE
·
2023
·
IF 3
Han Ziqi,Liu Zhihong,Li Qihou,Wang Kai,Yu Zhiqian,Xia Longgong
Ternary compounds in the Al–Te–O system have been considered as potential materials for Low-Temperature Co-fired Ceramics preparation. Two ternary compounds, Al 2 TeO 6 and Al 2 Te 2 O 7 , have been found in the Al–Te–O system under 920 °C in air. The decomposition behavior of these two compounds has been studied with Thermogravimetric Analysis-Differential Scanning Calorimetry (TGA-DSC) and equilibration experiments. Phase equilibrium of the Al 2 O 3 –TeO 2 system has also been experimentally investigated at ambient atmosphere, and corresponding phase diagram has been derived. Obtained results showed that Al 2 Te 2 O 7 , could only be found when TeO 2 was 66.7-70.0 mol pct and temperature was at 590 °C to 610 °C. Al 2 TeO 6 decomposed into Al 2 O 3 , TeO 2 (g), and O 2 (g) when temperature was above 920 °C. Al 2 Te 2 O 7 converted into Al 2 TeO 6 at 620 ± 2 °C, and then followed the decomposition path of Al 2 TeO 6 . In phase equilibrium study, when the initial sample started from the Al 2 O 3 –Al 2 TeO 6 region, Al 2 TeO 6 and Al 2 O 3 were found in quenched samples at the temperature range of 500 °C to 915 °C. When the initial sample started from the Al 2 TeO 6 –TeO 2 phase region, two solid phases, Al 2 TeO 6 and TeO 2 , could be found in samples prepared under 725 ± 2 °C. When the temperature was above 730 ± 2 °C, there were Al 2 TeO 6 and one oxide liquid phase. In the Al 2 Te 2 O 7 –TeO 2 region, all equilibrated samples had Al 2 Te 2 O 7 and TeO 2 .
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Life-Basel
·
2021
·Vol. 11
·期 5
·445
·
IF 3.817
Yang Deng,Ji Ma,Xin Weng,Yuqin Wang,Maoru Li,Tingting Yang,Zhiyang Dou,Zhiqi Yin,Jing Shang
NAFLD (non-alcoholic fatty liver disease) is one of the most prominent liver diseases in the world. As a metabolic-related disease, the development of NAFLD is closely associated with various degrees of lipid accumulation, oxidation, inflammation, and fibrosis. Ilex chinensis Sims is a form of traditional Chinese medicine which is used to treat bronchitis, burns, pneumonia, ulceration, and chilblains. Kaempferol-3-O-glucuronide (K3O) is a natural chemical present in Ilex chinensis Sims. This study was designed to investigate the antioxidative, fat metabolism-regulating, and anti-inflammatory potential of K3O. A high-cholesterol diet (HCD) was used to establish steatosis in larval zebrafish, whereby 1mM free fatty acid (FFA) was used to induce lipid accumulation in HepG2 cells, while H2O2was used to induce oxidative stress in HepG2. The results of this experiment showed that K3O reduced lipid accumulation and the level of reactive oxygen species (ROS) both in vivo (K3O, 40 μM) and in vitro (K3O, 20 μM). Additionally, K3O (40 μM) reduced neutrophil aggregation in vivo. K3O (20 μM) also decreased the level of malondialdehyde (MDA) and significantly increased the level of glutathione peroxidase (GSH-px) in both the HCD-induced larval zebrafish model and H2O2-exposed HepG2 cells. In the mechanism study,keap1,nrf2,tnf-α, andil-6mRNA were all significantly reversed by K3O (20 μM) in zebrafish. Changes in Keap1 and Nrf2 mRNA expression were also detected in H2O2-exposed HepG2 cells after they were treated with K3O (20 μM). In conclusion, K3O exhibited a reduction in oxidative stress and lipid peroxidation, and this may be related to the Nrf2/Keap1 pathway in the NAFLD larval zebrafish model.Keywords:non-alcoholic fatty liver disease;kaempferol-3-O-glucuronide;oxidative stress;inflammation;high-cholesterol diet.
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Inorganic Chemistry Frontiers
·
2021
·Vol. 8
·期 24
·5270-5276
·
IF 6.569
Shiwei Liu,Jiale Chen,Hongping Wu,Hongwei Yu,Zhanggui Hu,Jiyang Wang,Yicheng Wu
The dimensional reduction theory is applied to an A2O–P2O5–Bi2O3 system where P2O5 serves as a binary parent while A2O and Bi2O3 are regarded as dimensional reduction agents. Thus, three novel phosphates ACs5Bi4(PO4)2(P2O7)3 (A = K, Rb and Cs) have been prepared through the high-temperature solution method. Single-crystal X-ray diffraction measurements reveal that they all crystallize in the monoclinic space group P21/c (no. 14) and in their structures, two different kinds of P–O units, i.e. isolated PO4 tetrahedra and P2O7 dimers, are interconnected by Bi–O groups to construct a 3∞[Bi4(PO4)2(P2O7)36−] framework. Note that with the change of cationic size in their structures, the Bi3+ cations also exhibit flexible coordination, i.e. BiO5 and BiO6 polyhedra in KCs5Bi4(PO4)2(P2O7)3 and only BiO6 polyhedra in Cs6Bi4(PO4)2(P2O7)3, suggesting that combining the flexible coordination of Bi3+ cations with phosphates based on dimensional reduction theory is an effective strategy to guide the synthesis of new compounds.
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Xiao Zhang,Zhongping Yao,Yang Zhou,Zhirong Zhang,Guifeng Lu,Zhaohua Jiang
The construction of dual electron reaction centers is an attractive strategy to accelerate the rate-limiting step in Fenton-like catalyst. In this work, we constructed the dual electron reaction centers and electron transport path over C–O–Fe bridges connected by graphene oxide (GO) and Fe 3 O 4 through density functional theory (DFT). The calculations show that there is a strong interaction of C–O–Fe between GO and Fe 3 O 4 , and electrons around C would transfer to Fe along C–O–Fe linkages and the electron-rich reaction microcenters are generated around Fe. Based on it, Fenton-like catalyst of ultra-small Fe 3 O 4 (less than 10 nm) loaded on 3D reduced graphene oxide (rGO) (composite denoted as rGF) was successfully prepared. Characterization analyses have demonstrated that C–O–Fe bonds exist in rGF and CV test confirmed the cross-linked structure implemented by C–O–Fe is thermodynamically beneficial for electrons transport to Fe which is responsible for the regeneration of Fe(II). When the weight ratios of GO to Fe 3 O 4 reach 5%, rGF-5, the optimized composite displays superior Fenton-like performance that the removal efficiencies of tetracycline hydrochloride (TCH) are 98.7% within 60 min and 96.1% within 90 min, with the initial pH 4.5 and pH 6.7, respectively. The excellent cyclic stability of rGF-5 further verifies the structure of electron-rich reaction microcenters on C–O–Fe bond bridges is well established to ensure that Fenton-like reactions continue to occur efficiently. The results of mass spectrometry indicate that products with m / z = 114 converted from TCH ( m / z = 445) accounted for 87% at 60 min. This work not only achieves a way to construct high-performance heterogeneous Fenton-like catalysts for degradation of antibiotics, but also provides a new insight for designing various efficient catalysts based on the theoretical guidance.
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WASTE MANAGEMENT
·
2020
·
IF 5.448
Juan Luo,Junhao Lin,Rui Ma,Xing Chen,Shichang Sun,Peixin Zhang,Xiangli Liu
To study the effects of different ash/organics and C/H/O ratios on bio-fuel characteristics and energy efficiency, four kinds of sludge with different properties were used for microwave pyrolysis (800 °C). Moreover, the microwave pyrolysis reaction mechanisms of different sludge were also explored. The results showed that high-ash sludge could accelerate the frequency of polar molecule rotation in the microwave field due to the presence of oxides with dielectric properties in ash, thereby achieving faster heating rates and higher temperatures. However, compared with high-organic sludge, high-ash sludge exhibited lower bio-gas yield and higher bio-char yield. As the H/C ratio increased from 0.127 to 0.148, the bio-gas yield increased from 15.41% to 40.01%, and the content of H 2 in bio-gas and aliphatics in bio-oil increased to 36.69 vol% and 26.54 wt%, respectively. When the O/C ratio was reduced to 1.31, the content of CO and oxygenated compound in bio-oil increased to 31.25 vol% and 40.04 wt%, which lowered the quality of the bio-oil. Those consequences also determined that a mixture of sludge with different ash/organic ratios could be pyrolyzed to obtain high-quality bio-fuels and high energy efficiency. Differences in C/H/O ratios in the mixed sludge greatly affected the microwave pyrolysis heating process, which affected the pyrolysis reactions and the quality of the bio-fuels. Therefore, this study provides a theoretical basis to elevate the quality of bio-fuels and reduce microwave pyrolysis costs.
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