CHINESE CHEMICAL LETTERS
·
2013
·Vol. 24
·期 12
·1091-1094
·
IF 1.21
Xin-Ping Ouyang,Chun-Lei Liu,Yu-Xia Pang,Xue-Qing Qiu
A trimeric lignin model compound composed of α - O -4 and β - O -4 linkages was prepared by the microwave-assisted synthesis, which consisted of three steps: (a) the synthesis of 3-methoxy-4-benzyloxyacetophenone ( 2 ) from acetovanillone ( 1 ), (b) the bromination of compound 2 to produce 3-methoxy-4-benzyloxy- α -bromoacetophenone ( 3 ), and (c) followed by a nucleophilic substitution of compound ( 3 ) to obtain 3-methoxy-4-benzyloxy- α -(3-methoxy-4-(1-propenyl)phenol)-acetophenone ( 4 ). The target product was characterized by MS, 1 H NMR and 13 C NMR spectroscopy. It was found that the trimeric compound synthesized can be used as a preferable lignin model compound because it contains guaiacyl structural unit (3-methoxy-4-hydroxy phenyl propane) linked by α - O -4 and β - O -4 linkages. In addition, under the conditions of microwave irradiation, the reaction time of each step is significantly reduced, and the selectivity of target product is greatly improved. The yields of each step and the overall sequence are 95.31%, 87.3%, 90.6% and 75.4% (95.31% × 87.3% × 90.6%), respectively.
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APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Zhenhao Guan,Ying Zhang,Runpeng Liao,Jian Liu,Qicheng Feng,Shuming Wen
The present study investigated the interaction mechanism between α-nitroso-β-naphthol (αNβN) and smithsonite, and analyzed its performance in the dodecylamine (DDA) collector system. The results showed that at pH 8.0 and 10 mg/L DDA, the flotation recovery of smithsonite increased significantly from 19.64 % to 81.81 % after activation with 5 mg/L αNβN. In the DDA collector system, αNβN underwent chemical adsorption onto the smithsonite surface, which enhanced the hydrophobicity and zeta potential of the activated smithsonite. Density functional theory (DFT) and molecular dynamics (MD) simulation results confirmed that αNβN chemically adsorbed onto Zn sites on smithsonite via its nitroso group (R-N=O), reducing the water molecules concentration on the hydration film of smithsonite, and significantly enhancing the adsorption efficiency of DDA. This study demonstrated the superior performance of the novel activator in smithsonite flotation, providing a theoretical foundation for effectively replacing traditional sodium sulfide. This innovation not only improves flotation efficiency but also significantly reduces the negative impact on the environment.
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MACROMOLECULES
·
2025
·
IF 5.2
Ziyuan Zhou,Binghua Wang,Changyu Shen,Bin Zhang
Previous research studies on isotactic polypropylene (iPP) have shown that the ratio of growth rate β to α phase (Gβ/Gα) exceeds 1 when the crystallization temperature (Tc) is between the lower and upper critical temperature limits (Tc** ∼ 100 °C and Tc* ∼ 141 °C, respectively), due to the faster surface kinetics of β-iPP. However, in this work, we observed that when the film thickness (d) decreases from 24 to 9 nm, the temperature interval of Gβ/Gα > 1 narrows and even disappears, as Tc* gradually shifts to lower temperatures while Tc** remains constant. This is presumably because, as d decreases, the width (wd) of the depletion zone of β-iPP expands more significantly than that of α-iPP, resulting in slower diffusion toward the growth front of β-iPP. Consequently, Gβ decreases more than Gα as d diminishes, leading to a reduction in the value of Gβ/Gα, especially at higher Tc, where Gβ/Gα becomes less than 1. Moreover, we found that the diffusion activation energy (Eaβ) of β-iPP is consistently greater than that of α-iPP (Eaα) at a given d, and the gap between Eaα and Eaβ increases as d decreases. This further highlights that the slower diffusion process for β-iPP progressively becomes the main factor affecting the difference between Gα and Gβ as d diminishes.
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CHEMICAL ENGINEERING JOURNAL
·
2017
·
IF 6.216
Zheng Fang,Wei He,Tao Tu,Niuniu Lv,Chuanhong Qiu,Xin Li,Ning Zhu,Li Wan,Kai Guo
α-Fe 2 O 3 nanoparticles were prepared by using a continuous precipitation method with a valve assisted micromixer in the presence of iron (III) sulfate and ammonia water. The resulting nanoparticles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM). Meanwhile, CaCO 3 nanoparticles were synthesized in a tube-in-tube flow reactor AF-2400. The acylation process catalyzed by modified lipophilic α-Fe 2 O 3 and CaCO 3 nanoparticles in the flow reactor were systematically investigated. Under the optimal conditions, a yield of 97.8% was obtained. Addition of CaCO 3 nanoparticles resulted in higher catalytic efficiency compared with pure modified α-Fe 2 O 3 nanoparticles. Moreover, this novel acylation also worked well for other substrates.
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ORGANIC & BIOMOLECULAR CHEMISTRY
·
2017
·Vol. 15
·期 16
·3427-3434
·
IF 3.564
Dan Wang,Kuan Zhang,Luhan Jia,Danting Zhang,Yue Zhang,Yujia Cheng,Chang Lin,Bo Wang
Presented here is the first example of synthesizing an array of primary-, secondary-, and tertiary-α-ketoamides with a non-metal catalyst nBu4NI from methyl ketones and inexpensive readily available amine/ammonium salts; the reactions proceeded smoothly under mild conditions, TBHP was used as an oxidant and the corresponding α-ketoamides were afforded in moderate to excellent yields.
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PubMed
高影响因子
GREEN CHEMISTRY
·
2025
·
IF 9.2
Keyi Huang,Chengqi Zhao,Zixuan Xu,Qing Zhao,Huiqin Xu,Xiaomin Zhang,leizhi zheng,You-Ting Wu
The efficient capture and conversion of hydrogen sulfide (H2S) represent a critical challenge in addressing key issues in energy and environmental fields. In this study, we innovatively designed and synthesized a series of carbonyl-functionalized metallic ionic liquids (CMILs), which exhibit dual functionality as both absorbents and catalysts under mild conditions. Experimental results demonstrate that the [Na-15C][LA] system delivers outstanding performance under ambient conditions (30 ℃, 1.0 bar), achieving an H 2 S absorption capacity of 1.73 mol/mol, H 2 S/CO 2 selectivity of 101.2, and an exceptionally high H 2 S/CH 4 selectivity of 1122.2. NMR, FT-IR, and DFT calculations confirm that the carbonyl group serves as the active site for efficient H 2 S capture.Notably, these CMILs function as highly effective catalysts, facilitating the solvent-free conversion 2 of H 2 S with α, β-unsaturated carboxylates into thiols and thioethers under mild conditions. Moreover, the system enables spontaneous phase separation between the catalyst and products without requiring additional components, achieving quantitative conversion (> 99%) while adhering to green chemistry principles. This integrated design provides a novel technical approach for the efficient capture and resource utilization of H2S.
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产品关联
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高影响因子
PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Yuhua Lei,Yuhang Han,Xun Cheng,Chunxia Chen,Baipei Liu,Miaojun Xu,Yande Liu,Bo Jiang,Bin Li,Dawei Jiang
α-Chitin, as a natural bio-based polyol, possesses significant potential in bio-based green coatings. However, its intractable solubility and poor processability resulting from robust intermolecular hydrogen bonding and high crystallinity have long impeded the development and application of high-performance, environmentally friendly biomass coatings. To address this challenge, we propose a novel “hydrogen-bond network reconstruction” strategy. Through physicochemical co-modification disrupting chitin's microstructure, we successfully overcame its solubility barrier. Using this highly soluble chitin as the matrix and integrating flexible polydimethylsiloxane (PDMS) with hexamethylene diisocyanate trimer (HDIT) crosslinking technology, we fabricated an omniphobic coating with exceptional comprehensive properties. This coating exhibits an ultra-low surface energy (17 mJ·m −2 , lower than PTFE) and a densely cross-linked network, demonstrating not only superhydrophobicity/superoleophobicity with high contact angles (water: 110.7 ± 0.8°, diiodomethane: 80.9 ± 1.9°), excellent self-cleaning capability, and efficient anti-fouling/anti-graffiti properties, but also, owing to its reinforced network structure, remarkable mechanical stability (6H pencil hardness, A1-grade adhesion, abrasion resistance) and chemical resistance (tolerance to chemical agents, no corrosion after 10-day saline immersion, 20-fold reduction in corrosion current density ( I corr ) compared to bare iron). Simultaneously, it maintains high optical transparency (95 %). This coating provides a green, durable, and easy-to-maintain protective solution for precision devices such as electronic displays and solar panels, significantly extending service life while reducing cleaning energy consumption. This work establishes a foundation for developing high-performance biomass coatings integrating both ecological sustainability and industrial value via “hydrogen-bond network reconstruction” and green manufacturing pathways.
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高影响因子
Food Bioscience
·
2025
·
IF 5.9
Cheng Ma,Zhongyang Li,Jiangli Lin,Bin Wu,Shuailian Zhao,Xiaojing Yao,Xiuling Zhu,Xiangyun Wei,Shishan Zhou
Ultrasound-assisted purification was employed to extract and refine polyphenols from dried apricots. The inhibitory mechanism of these ultrasonically purified polyphenols against porcine pancreatic α-amylase (PPA) was investigated through inhibition kinetics, fluorescence spectroscopy, circular dichroism (CD) spectroscopy, molecular docking, and molecular dynamics (MD) simulations. UHPLC–MS/MS analysis identified 19 phenolic compounds in the purified polyphenols (PP), with rutin, morin, and isoquercetin as the predominant constituents. Enzyme inhibition assays demonstrated that PP exhibited strong inhibitory activity (IC 50 = 3.46 ± 0.20 mg/mL) and acted as a mixed-type inhibitor, whereas the three monomeric polyphenols showed competitive inhibition. Fluorescence and CD analyses revealed that both PP and its major monomeric components induced conformational changes in the secondary structure of PPA by altering the hydrophobic microenvironment surrounding tryptophan and tyrosine residues, thereby reducing enzymatic activity. MD simulations confirmed the structural stability of the polyphenol-PPA complexes, and binding free-energy calculations indicated that rutin and isoquercetin exhibited stronger binding affinity and higher complex stability than morin, primarily mediated by hydrogen bonding and hydrophobic interactions. Collectively, this work provides a comprehensive understanding of the inhibitory mechanism of ultrasonically purified dried apricot polyphenols and their key constituents against PPA. These findings establish a theoretical basis for the efficient purification of polyphenolic compounds and their potential application as natural hypoglycemic agents.
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高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Ri Chen,Jingjing Zhao,Zhongquan Sui,Dganit Danino,Harold Corke
In this study, α-amylase was used to assist starch nanoparticles (SNP) production through debranching and nanoprecipitation. The molecular structure, aggregation behavior, morphological properties, and digestibility of SNP were investigated. α-amylase hydrolysis pretreatment for 4 h increased the short-chain ratio of SNP, with a peak at DP = 13. This facilitated the formation of smaller and more uniform SNP, particularly at higher antisolvent concentrations. With α-amylase pretreatment, the small molecules reduced steric hindrance and interparticle interaction, resulting in a compact structure and well-defined boundaries during nanoprecipitation as indicated by cryo-EM. The crystalline pattern was mostly influenced by the solvent-to-antisolvent ratio. Prolonging α-amylase hydrolysis time led to loss of long-range crystalline order in SNP, while promoting the formation of submicron crystallites. Additionally, pretreatment increased slowly digestible starch and resistant starch ratios, leading to a lower glycemic response, thereby improving their functional performance. These findings offer valuable insights for optimizing the nanoprecipitation to produce SNP with controlled size and morphology, which enhances their potential as carriers in delivery systems.
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高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2024
·Vol. 59
·期 3
·1761-1769
·
IF 2.6
Jing Zhao,Wenwei Chen,Hua Liu,Xiaosan Zhang,Fei Tao,Zhenbao Jia
Summary Inhibition of α-glucosidases is recognised as an effective approach towards managing postprandial hyperglycaemia. This study aimed to identify a specific compound in Carya cathayensis Sarg. kernels (CCSKs) exhibiting strong inhibitory activities against α-glucosidase and elucidate the inhibitory kinetic mechanism. Employing a bioassay-guided approach, an α-glucosidase inhibitor was isolated from CCSKs through sequential chromatography protocol involving AB-8 macroporous adsorptive resin, Sephadex LH-20 and C 18 -reversed phase silica gel. The resulting inhibitor was a novel tannin compound, identified as rugosin C ethyl ester. Rugosin C ethyl ester displayed superior inhibitory activity (IC 50 of 2.60 μg/mL) compared to acarbose (IC 50 of 105.95 μg/mL). The kinetic analysis indicated that rugosin C ethyl ester had a mixed-type reversible inhibition against α-glucosidase. The inhibition constants ( K i and K is ) were determined to be 3.119 and 0.856 μg/mL, respectively. The findings indicated that rugosin C ethyl ester might serve as a promising functional ingredient in low-glycemic index foods.
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Frontiers in Energy Research
·
2022
·
IF 3.858
Baimoldina Adel,Papadikis Konstantinos,Konysheva Elena Yu.
The incorporation of mono-sized particle catalysts in real industrial systems for biomass conversion is a significant challenge, hence the impact of individual α-Fe2O3 catalysts with varying non-ideal spherical sizes of 54 nm (FS054), 221 nm (FS221), and ∼2 µm (FSm002) as well as dual-sized mixtures (FS054-FS221 and FS221-FSm002) were considered in the catalytic upgrading of pinewood pyrolysis vapors. The size variation of the α-Fe2O3 catalyst revealed a substantial effect on the product distribution. Although the yield of phenols shows a decrease by almost a factor of two irrespective of the catalyst particle size, the FS221 catalyst demonstrates the most potent effect on reducing phenols through decarboxylation reactions. Considering the role of the catalyst on the individual phenolics, the FS221 catalyst reveals higher selectivity towards the reduction of 2-methoxyphenol, isoeugenol, and eugenol, whereas the application of FS054 catalysts displays a stronger impact on the decrease of creosol and other phenols. Both FS054 and FS221 catalysts showed the highest effectiveness in reducing the relative yield of 2-methoxy-4-vinylphenol. Applying a dual-size mixture (FS054-FS221) shows a synergetic effect, simultaneously decreasing the content of phenols, acids, and aldehydes followed by a strong CO2 release attributed to competitive decarbonylation reactions of aldehydes. The appearance of γ-Fe2O3 small fraction was revealed in the powders with mono-(FS221) and dual particle size (FS054-FS221 and FS221-FSm002), whereas the FS054 and FSm002 catalysts demonstrate good chemical and phase stability.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2019
·
IF 14.229
Quan Huo,Xiaoran Qi,Jianshu Li,Gongquan Liu,Yao Ning,Xubiao Zhang,Boyu Zhang,Yanfei Fu,Suyan Liu
A series of direct Z-scheme α-Fe 2 O 3 /MIL-101(Cr) hybrids were successfully prepared through a facile hydrothermal method in this work. And, the materials were characterized by some technologies including X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), N 2 adsorption-desorption, photoluminescence (PL) spectroscopy, Ultraviolet-visible (UV–vis) diffuse reflectance spectroscopy (DRS) and electron spin resonance (ESR). The photocatalytic activities of the hybrids were evaluated by degradation of carbamazepine (CBZ) under visible light irradiation. It is found that 100% of CBZ was able to be removed after 180 min irradiation over the optimum α-Fe 2 O 3 (0.3)/MIL-101(Cr) hybrid. The superior activity was engendered from good textural properties and the formation of a direct Z-scheme heterojunction in the hybrid. The decomposition process of CBZ and the formation of intermediate products were analyzed through liquid chromatography-tandem mass spectrometry (LC–MS) and a possible photodegradation pathway of the CBZ was proposed. Also, the possible mechanism for the photodegradation process was provided to illustrate the excellent performance. The work has paved a new way for the application of MOF materials in the design of efficient Z-scheme system for organic pollution degradation in wastewater.
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