JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2011
·
IF 3.068
Jingpeng Yuan,Yongchao Lai,Junling Duan,Quanqin Zhao,Jinhua Zhan
A mono-6-thio-β-cyclodextrin-modified silver film was synthesized via galvanic displacement on copper foil. The prepared silver films could enrich non-polar polychlorinated biphenyls (PCBs) molecules from hydrophilic phase using thiolate β-cyclodextrins (SH-β-CDs) as receptors. The components of as-prepared Ag-coated-Cu (Ag–Cu) film were confirmed by powder X-ray diffraction (XRD). Both surface-enhanced Raman spectroscopy (SERS) and energy dispersive X-ray spectroscopy (EDS) measurements gave strong evidences that the thiolated β-cyclodextrins (SH-β-CDs) had been immobilized on the surface of silver film. Compared to the substrates prepared in the absence of SH-β-CD, the surface morphology of the CD-modified Ag films was obviously changed. The interfacial enrichment and the capability of substrates to form inclusion complexes with PCBs molecules were tested by using PCB-15 (4,4′-dichlorobiphenyl) as the probe molecules via SERS technique. The measured SERS spectra could distinguish the PCB-15 molecules at micro-molar level according to the most intense CCC bending in-plane mode of PCBs. The enhancement factor (EF) of the SERS substrates for PCB-15 was 1.2 × 10 5 , which was comparable with a number of previous reports.
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高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Qing Yang,Hongbin Pu,Da-Wen Sun
The sensitive detection of quinalphos in food is crucial due to its improper use and the potential for serious harm. Surface-enhanced Raman spectroscopy (SERS) technology, provides a new way for rapid and ultra-sensitive detection. To exploit the molecular sieving effect of metal-organic frameworks (MOFs) in mitigating interference from food matrix components during pesticide residue detection, a novel chiral spiny L-Au@Ag@ZIF-8 (L-AAZ) three-layer core-shell composite was developed as an effective SERS substrate, with chiral L-AABPs providing abundant “hot spots” and spiny ZIF-8 shell provides excellent absorption properties, causing a five-fold increase in SERS intensity compared to traditional Au@Ag NPs. The experimental results revealed that L-AAZ achieved a high enhancement factor (EF) of 3.15 × 10 5 , a low limit of detection (LOD) of 6.56 × 10 −10 M, and a relative standard deviation (RSD) of 14.6 % for malachite green (MG), indicating its superior SERS sensitivity and consistency. Moreover, it demonstrated stable performance, maintaining good storage stability for up to 55 days. The substrate's suitability for the actual fruit sample (tangerine) was confirmed, showing an LOD of 10 ng/mL, demonstrating its capability for rapid and sensitive detection of trace amounts of pesticide residues in food.
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DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Xiaoyi Rong,Shaojie Gong,Jinqing You,Lin Geng,Wenzhong Yang,Hui Xu
Surface-enhanced Raman scattering (SERS) stands out as a valuable tool for the rapid and precise detection of trace antibiotics. However, preparing SERS substrates with high sensitivity, homogeneity, and good stability remains a great challenge. In this study, we chemically functionalized graphene oxide (GO) with poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) through surface-initiated atom transfer radical polymerization (SI-ATRP) technique. Then, GO- g - q PDMAEMA was obtained by quaternization (the quaternized PDMAEMA is denoted as q PDMAEMA). Using a water/oil interface self-assembly approach, we fabricated GO- g - q PDMAEMA/AuNPs nanofilms by interfacial assembly between GO- g - q PDMAEMA in chloroform and AuNPs in water. The nanofilms exhibited remarkable SERS characteristics, including exceptional sensitivity, good homogeneity, reproducibility, and stability. Additionally, two commonly used antibiotics, i.e., sulfamonomethoxine (SMM) and enrofloxacin (ENR) were rapidly and sensitively detected using the prepared GO- g - q PDMAEMA/AuNPs nanofilms as a SERS platform. The developed GO- g - q PDMAEMA/AuNPs nanofilms hold significant promise for food safety monitoring and environmental analysis.
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高影响因子
TALANTA
·
2025
·
IF 6.1
Shuojiang Liu,Ying Chen,Xingliang Cheng,Gongke Li,Yuling Hu
Surface-enhanced Raman scattering (SERS) in conjunction with nanozymes has emerged as a powerful technique for bioanalysis due to their signal conversion and amplification effect. However, clinical applications continue to encounter challenges such as inadequate selectivity. Herein, we proposed a novel approach for the selective SERS detection of L-DOPA in human serum with dual enzyme-mimicking MOF-919(Fe–Cu). This material exhibits both catechol oxidase-like and peroxidase-like activities, enabling it to catalyze catecholic compounds to o -quinones and subsequently oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) molecules into SERS-active ox-TMB. Ultrasonic-assisted synthesis ensures uniform and dense loading of AgNPs within MOF-919(Fe–Cu), thereby enhancing SERS activity. A sensitive and selective method for SERS detection of L-DOPA was developed. The catechol oxidase-like activity of MOF-919(Fe–Cu) provides ideal selectivity and anti-interference to L-DOPA, while the cascade catalytic system transforms weak SERS signals of L-DOPA into amplified SERS signals of ox-TMB. The mechanism of dual enzyme-mimicking activity was further discussed. The detection process was optimized to achieve high sensitivity towards L-DOPA with a linear range 0.5–100 μmol/L and low limit of detection (LOD) of 0.16 μmol/L. Furthermore, it has been applied in serum sample of Parkinson's patients, demonstrating excellent recovery and low relative error compared to HPLC-UV. This approach offers an economical, efficient and accurate strategy for the detection of L-DOPA and provides valuable insights for the integration of selective multifunctional nanozyme and sensitive SERS detection method.
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DOI
PubMed
高影响因子
Food Bioscience
·
2025
·
IF 5.9
Xuan Fu,Limei Yin,Yang Zhang,Zongbao Sun,Shanshan Xue,Heera Jayan,Hesham R. El-Seedi,Xiaobo Zou,Zhiming Guo
Aflatoxin B1 (AFB1) is a typical toxin found in maize, leaving severe threats to human health and livestock. A dual-signal SERS-fluorescence aptasensor was constructed to detect Aflatoxin B1. Hollow mesoporous silica nanoparticles functionalized with amino groups (AHMSN) were designed as carriers for the dual-signal molecule Rh6G. The aptamer, adsorbed onto the surface of AHMSN Rh6G via electrostatic interactions, acted as a “gate” to block the release of Rh6G. Simultaneously, the noble metal nanocomposite Au@Ag NRs was developed as the SERS substrate. The strong and selective interaction between the aptamer and AFB1 led to the release of Rh6G, resulting in SERS and fluorescence signals that were positively correlated with the concentration of AFB1. The LOD of SERS and fluorescence were 0.0092 ng/mL and 0.0050 ng/mL, respectively. At the same time, the sensor demonstrated good accuracy in detecting AFB1 in various maize meal/oil samples, showing strong practical applicability. This research developed a highly specific and sensitive dual-mode detection method for AFB1, circumventing the need for aptamer chemical modification or the incorporation of complementary strands. This approach presents a simplified, cost-efficient, and versatile strategy for AFB1 detection.
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高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Xishun Peng,Yiheng Yuan,Anjiang Lu,Cunwei Wang,Caizhen Zu,Haili Zhang,Zhongchen Bai
Glyphosate (Gly) residues in agricultural products have a serious health risk, so it is urgent to seek a sensitive and convenient method for recognizing Gly residues in food. In this study, we proposed an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) sensor of polyaniline/reduced graphene oxide/Ag/Cu (PANI/RGO/Ag/Cu) film to detect Gly residues. The EC-SERS sensor of PANI/RGO/Ag/Cu film had a large specific surface area, which could increase the binding sites of cu 2+ /Gly clathrates for boosting specifically its SERS signal. Moreover, Ag/Cu nanoparticles on the surface of film could effectively increase the differential pulse voltammetry signal and SERS signal of Gly molecules. The limit of detection of EC-SERS sensor to Gly could reach 1.9 nM. In addition, the EC-SERS sensor we prepared could also sensitively identify Gly residues on fresh fruit peels. The PANI/RGO/Ag/Cu film we proposed in this paper has great potential for selective and accuracy detecting Gly residues in agricultural products.
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PubMed
高影响因子
Food Bioscience
·
2025
·
IF 5.9
Zhiqiang Wang,Chenguang Yi,Guiqing Wen,Aihui Liang,Zhiliang Jiang
Two new nanosurface molecularly imprinted covalent organic framework nanoprobes (MICOF) with recognition and catalytic amplification di-functions for the detection of trace endocrine disruptor nonylphenol (NPN) in milk were synthesized, gold nanocluster (AuNC)/nanopolyvinylchloride (PVC) as substrates, NPN as the template molecule, benzidine and 2,4,6-triformylphloroglucinol as the functional monomers. The di-nanoprobes efficiently catalyzed a new indicator nanoreaction between HAuCl 4 and triethanolamine to generate gold nanoparticles (AuNPs) with SERS effect. Surprisingly, under ultrasonic irradiation, the di-nanoprobes exhibited extremely strong catalysis, due to the triboelectric nanogenerator (TENG) constructed. The AuNC@COF was positive and the PVC@COF was negative, with an increase in catalytic activity of 680%. When NPN was added, it was selectively adsorbed in the nanoprobe imprinted sites, further enhancing catalysis. The working curve slope was increased by 2000%, with a linear range of 0.2-10 nmol/L and limit of detection (LOD) was 0.060 nmol/L NPN. The method was applied to the determination of milk with relative deviations (RSD) of 0.97-9.6% and recovery of 90.4-109.8%. In addition, this new SERS quantitative analysis method was also used to determine phenol, bisphenol A and 1-naphthol with LOD were 0.080, 0.060 and 0.12 nmol/L respectively, which proved that it is of universality and high sensitivity. The ultrasonic driven MICOF di-probe TENG catalytic enhancement mechanism was constructed.
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高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Yue Mao,Borong Yu,Huijiao Zhang,Yuanyuan Ma,Fangwei Han,Binbin Zhou,Lili Yang,Zhangang Han
The work reported on the preparation of expanded graphite (EG) coupled with Ag nanoparticles for quick water contaminant adsorption, followed by trace molecules sensing using SERS technique. The surfactant-free composites of Ag/EG were obtained by a simple and controllable “mix-and-heat” mechanochemical method. Most of the analytes were found to be adsorbed within 15 min without any additional physical or chemical activation and its adsorption behavior at room temperature fitted pseudo-second-order kinetic models. As SERS enhanced substrate, less than 10 ppb of crystal violet (CV) and methylene blue (MB) could be determined via Ag/EG. What’s more, the Ag/EG substrate could adapt to strong acid and alkali environment and could be stored for as long as 120 days. Therefore, the composites Ag/EG could be used as a reliable SERS active substrate. Moreover, the substrate could be reused at least four times. In addition, ‘adsorption-filtration’ was conducted through a homemade filter and the filter membrane was employed as substrate support instead of silicon wafers. Such results reveal that Ag/EG as a solid SERS substrate has great potential value for practical applications. And the study provides a new strategy for the development of high-performance sensing of the target analyte in the future.
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ACS Applied Nano Materials
·
2022
·
IF 6.14
Baichuan Zhao,Huihui Liu,Lingzhi Xia,Zhi Wang,Congyun Zhang
The development of powerful technologies to simultaneously monitor and eliminate toxic organic pollutants is a vital focus of environmental research. For this purpose, a recyclable surface-enhanced Raman scattering (SERS) substrate was successfully prepared by successively depositing gold nanoparticles (AuNPs) and a reduced graphene oxide (rGO) film on TiO2 microflower particles by two-step in situ reduction processes. The prepared TiO2@Au-rGO ternary composites exhibit not only good SERS performance via molecule enrichment of rGO and surface plasmon resonance (SPR) capability, but also enhanced photocatalytic degradation activity because of the increased broadband UV–visible-light-harvesting efficiency and SPR-enhanced charge transfer. The detection limit of rhodamine 6G (R6G) as low as 10–11 M and excellent reproducibility were achieved. Additionally, the TiO2@Au-rGO ternary composites yield complete removal of R6G within 15 min under broadband UV–visible light illumination, wherein their apparent reaction-rate constant is 2.8 and 5.5 times larger than those of binary TiO2@Au and pure TiO2, respectively. Meanwhile, no distinct SERS and photocatalytic activity loss were observed even after five reusability tests, achieving the recycling SERS application by photocatalytic degradation. Most importantly, the as-fabricated ternary samples can be explored for the efficient capture, sensitive detection, and self-cleaning degradation of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47), revealing great potential applications in the SERS-based simultaneous monitoring and removal of trace aromatic persistent organic pollutants.
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高影响因子
Analytical Methods
·
2014
·Vol. 6
·期 23
·9348-9353
·
IF 1.938
Fei Wang,Yang Qiu,Peng-Bo Fu,Hua-Lin Wang,Yi-Tao Long
A novel method for reliable on-site characterization of aromatic compounds adsorbed on porous particles with surface enhanced Raman spectroscopy (SERS) in a dynamic adsorption-hydrocyclone separation process (DAHS) was introduced. Aromatic compounds found in printing and dyeing wastewater were adsorbed on functionalized porous alumina particles (FPAPs). The SERS-active FPAPs were prepared by decorating and growing silver nanoparticles (Ag NPs, ∼70 nm diameter) on the surface of porous alumina particles (PAPs). Samples were then characterized with a portable Raman spectrometer. SERS offers quantitative analyses of the pollutants adsorbed on the surface of FPAPs directly and the quantity of benzidine adsorbed on porous particles was 20.5 mg kg−1. It shows that the SERS-DAHS technique could be readily applied to the quantitative characterization of aromatic compounds adsorbed on SERS-active FPAPs. Furthermore, both qualitative and quantitative detection of aromatic compounds in wastewater produced on-site were readily accomplished using the SERS-DAHS method and its analytical ability compares well with GC-MS and the detection results deviating between these two techniques was less than 10%. The results demonstrate that the SERS-DAHS method is straightforward, rapid, and preferable for the real-time detection and quantitative characterization of aromatic compounds/pollutants adsorbed on porous materials.
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高影响因子
JOURNAL OF RAMAN SPECTROSCOPY
·
2017
·Vol. 48
·期 4
·578-585
·
IF 2.969
Hengyong Wei,Mingming Wu,Zhanliang Dong,Ying Chen,Jinglong Bu,Jian Lin,Yun Yu,Yingna Wei,Yi Cui,Ruisheng Wang
The titanium nitride thin film was successfully prepared via direct nitridation of the sol–gel derived TiO 2 thin film at different temperatures in ammonia gas. The composition, microstructure and optical properties of the thin films were characterized in order to investigate their effect on the surface-enhanced Raman scattering (SERS) performance of the thin films. With the nitridation temperatures increasing, the anatase phase transformed into titanium nitride phase in the films and the concentration of nitrogen incorporation increased accordingly. Consequentially, the sol–gel derived TiO 2 thin film was converted to non-stoichiometry titanium nitride (TiO x N y ) thin film, as determined by X-ray diffraction (XRD), RAMAN and X-ray photoelectron spectroscopy (XPS). As a result, a blue-shift of the surface plasmon resonance absorption peaks and narrowing optical band gap of the thin films were observed, leading to the improvement of SERS performance via electromagnetic enhancement mechanism and charge-transfer effect. In addition, the surface of thin films became gradually rough with the nitridation temperatures increasing, ascribed to the growth of titanium nitride crystal grains. Most of all, the thin films nitrided at 1000 °C had the most rough surface, and many ‘hot spots’ formed on the thin film surface accordingly, which were favorable for enhancing SERS-active, and thereby the thin films exhibited the largest SERS enhancement. Copyright © 2017 John Wiley & Sons, Ltd.
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Analytical Methods
·
2019
·Vol. 11
·期 23
·2960-2968
·
IF 2.378
Le Peng,Jun Zhou,Zhaoheng Liang,Yaping Zhang,Lucia Petti,Tao Jiang,Chenjie Gu,Danting Yang,Pasqule Mormile
Based on surface-enhanced Raman scattering (SERS) technology, Au@Ag@4MBA@5′-NH2-ssDNA probes and a Ag/TiO2@3′-NH2-ssDNA substrate were prepared and constructed into a sandwich structure to develop a high sensitivity bioassay of miRNA-21. The Au@Ag@4MBA@5′-NH2-ssDNA probes were prepared by immobilizing 5′-NH2-ssDNA onto the surfaces of 4MBA-labelled Au@Ag core–shell nanoparticles, and the Ag/TiO2@3′-NH2-ssDNA substrate was prepared by immobilizing 3′-NH2-ssDNA on the surface of Ag/TiO2 nanowires SERS-active substrates. The experimental results showed that the SERS-based sandwich bioassay of miRNA-21 presented a low limit of detection of 0.75 fM and a broad dynamic range from 1.0 fM to 1.0 nM. Also, the test data for the SERS-based sandwich bioassay were not only consistent with that of the real-time fluorescence quantitative polynucleotide chain reaction (RT-qPCR) method but also displayed higher detection sensitivity. It was shown that the SERS-based sandwich bioassay of miRNA-21 has importance for use in potential applications involving diagnosing clinical cancer patients.
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