CELLULOSE
·
2021
·Vol. 28
·期 18
·11713-11727
·
IF 5.044
Su Minglei,Zhang Rong,Li Jingpeng,Jin Xiaobei,Zhang Xiaofeng,Qin Daochun
Bamboo, as a fast-grown forest resource, can be functionalized by metal–organic frameworks (MOFs) with various potential applications. However, the stability of MOFs immobilized on bamboo surface remains to be improved. In this work, MOF199, as known as HKUST-1, was in situ anchoring on moso bamboo via regulating pretreatment of bamboo and a green two-step synthesis route. The two-step synthesis route was completed under room temperature and both precursor solutions can be reused. The results indicated that, with the collaboration of delignification and carboxymethylation pretreatment of bamboo, a dense and well-dispersed MOF coating was successfully synthesized, the adhesion between MOF199 and bamboo surface was also improved. Besides, the quantity and size of MOF199 on bamboo can be tailored by tunning the carboxyl groups of pretreated bamboo and the concentration of copper nitrate solution. More importantly, results show that the formation of carboxyl-copper (II) complex served as nucleation sites for the growth of MOF199 crystals, which was essential to prepare uniform MOF layers. The growth of MOF199 endowed bamboo with good antibacterial activity against Escherichia coli . This method provides a facile and practical strategy for designing MOF coated woody materials. Graphic abstract
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Nature Chemical Biology
·
2021
·Vol. 18
·期 1
·47-55
·
IF 15.04
Chen Chao,Yu Guiling,Huang Yujia,Cheng Wenhui,Li Yuxuan,Sun Yi,Ye Haifeng,Liu Tao
Inducer-triggered therapeutic protein expression from designer cells is a promising strategy for disease treatment. However, as most inducer systems harness transcriptional machineries, protein expression timeframes are unsuitable for many therapeutic applications. Here, we engineered a genetic code expansion-based therapeutic system, termed noncanonical amino acids (ncAAs)-triggered therapeutic switch (NATS), to achieve fast therapeutic protein expression in response to cognate ncAAs at the translational level. The NATS system showed response within 2 hours of triggering, whereas no signal was detected in a transcription-machinery-based system. Moreover, NATS system is compatible with transcriptional switches for multi-regulatory-layer control. Diabetic mice with microencapsulated cell implants harboring the NATS system could alleviate hyperglycemia within 90 min on oral delivery of ncAA. We also prepared ncAA-containing ‘cookies’ and achieved long-term glycemic control in diabetic mice implanted with NATS cells. Our proof-of-concept study demonstrates the use of NATS system for the design of next-generation cell-based therapies to achieve fast orally induced protein expression.
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Scientific Reports
·
2021
·Vol. 11
·期 1
·1-11
·
IF 4.38
Hu Keling,Sui Huachao,Zhao Dongping
Naturally occurring nipagin and eugenol were used as the collaborative starting materials for poly(ether ester) polymers. In this study, two series of nipagin and eugenol-derived copoly(ether ester)s, PHN1 1−x E1 x and PHN1 1−x E2 x (x = 0%, 5%, 10%, 15%, 20%), were prepared with renewable 1,6-hexanediol as a comonomer. The nipagin-derived component acts as the renewable surrogate of petroleum-based dimethyl terephthalate (DMT), while the eugenol-derived component acts as the cooperative property modifier of parent homopoly(ether ester) PHN1. 1,6-Hexanediol was chosen as the spacer because of its renewability, high boiling point, and short chain to enhance the glass transition temperatures ( T g s) of materials. The molecular weights and chemical structures were confirmed by gel permeation chromatograph (GPC), NMR and FTIR spectroscopies. Thermal and crystalline properties were studied by thermal gravimetric analysis (TGA), differential scanning calorimetric (DSC) and wide-angle X-ray diffraction (WXRD). The tensile assays were conducted to evaluate the mechanical properties. The results suggested that properties of this kind of poly(ether ester)s could be finely tuned by the relative content of two components for the desired applications (elastomer, rubbery) suitable for different scenarios from polyethylene glycol terephthalate (PET) and polybutylene terephthalate (PBT).
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WATER AIR AND SOIL POLLUTION
·
2021
·Vol. 233
·期 1
·1-9
·
IF 2.52
Yu Hui-Bo,Zhang Xian-Qiu,Han Xue,Yang Zhen-Zhen,Zhou Ya-Wen,Ding Wen,Du Ming-Xia
It is reported that residual aluminum from coagulation pretreatment can increase membrane fouling in nanofiltration (NF) or reverse osmosis (RO) desalination systems. However, the membrane fouling mechanism of residual aluminum and the effective control measures are not very clear. In this study, the nanofiltration membrane fouling caused by poly-aluminum chloride (PACl), the inhibitory effect of amino trimethylene phosphonic acid (ATMP) on aluminum foulants, and calcium carbonate scale in the presence of residual aluminum were investigated by permeate experiments and scanning electron microscopy (SEM) observation of the fouled membranes. Besides, the effect of adding ultrafiltration before nanofiltration on reducing membrane fouling caused by residual aluminum was also investigated. The results showed that most of the residual aluminum in feed eventually formed insoluble particles and fine flocs, and accumulated gradually on the membrane surface, which was a typical colloid particle fouling. ATMP can reduce the membrane fouling caused by residual aluminum to some extent, and the permeate flux ratio ( J/J c ) increased from 0.83 to 0.89 when ATMP increased to the optimal dose of 6 mg⋅L −1 . However, this means can still effectively eliminate carbonate scale, even in the presence of residual aluminum. Moreover, ultrafiltration pretreatment prior to nanofiltration was very effective to control membrane fouling, and the comprehensive cost was calculated to be only 0.006 $⋅m −3 . Therefore, the combined process of coagulation-ultrafiltration as a pretreatment of nanofiltration or reverse osmosis should be an ideal way to prevent membrane fouling caused by residual aluminum.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2021
·Vol. 37
·期 6
·1296-1300
·
IF 1.307
Rong Xin,Lu Xiuli,Lu Tongbu
T he fabrication of highly active and easily recyclable Pd-based catalyst is meaningful for their practical application. Herein, a Pd-based dip-catalyst(Pd@Pyr-GDY) is fabricated on graphdiyne(Pyr-GDY) grown on copper foam, and applied in the reduction of nitroarenes. Specially, the as-formed Pd@Pyr-GDY shows good catalytic performance toward the reduction of 4-nitrophenol(4-NP) to 4-aminophenol(4-AP) by NaBH 4 with a rate constant k value of 3.84 min −1 , which is 12-fold higher than that of the commercial Pd/C. More importantly, Pd@Pyr-GDY could be easily and rapidly recovery from the reaction medium and no distinct inactivation was found after six cycles of the reaction. This work presents an easy way to design an efficient and easily recyclable Pd-based catalyst for practical use.
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Journal of Central South University
·
2021
·Vol. 28
·期 4
·1233-1243
·
IF 1.716
Rao Wei-dong,Liu Yao,Cheng Li-jing,Liu Shao-jun
Combining sintering additive with field assisted sintering, stereolithographical dense Si 3 N 4 ceramics was successfully fabricated. Owing to a large amount of polymer during the stereolithography, the green parts have the characteristics of low powder loading and high porosity. Adjusting the process parameters such as sintering temperature and soaking time can effectively improve the density of the specimens. The stress exponent n of all specimens is in a range of 1 and 2, which is derived from a modified sintering kinetics model. The apparent activation energy Q d of stereolithographic Si 3 N 4 ceramics sintered with applied pressures of 30 MPa, 40 MPa, and 50 MPa is 384.75, 276.61 and 193.95 kJ/mol, respectively, suggesting that the densification dynamic process is strengthened by raising applied pressure. The grain boundary slipping plays a dominating role in the densification of stereolithographic Si 3 N 4 ceramics. The Vickers hardness and fracture toughness of stereolithographic Si 3 N 4 ceramics are HV10/10 (1347.9±2.4) and (6.57±0.07) MPa·m 1/2 , respectively.
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Advanced Composites and Hybrid Materials
·
2021
·Vol. 5
·期 1
·91-103
·
IF 5.693
Zhu Tengyang,Zhao Xiaoxu,Yi Ming,Xu Sheng,Wang Yan
To eliminate the interfacial defects between polymeric matrix and inorganic fillers in hybrid membranes, various strategies have been proposed by modifying membrane materials or optimizing membrane formation process. In this work, a ternary cross-linked PVA-APTES-ZIF-90 (PVA, poly(vinyl alcohol); APTES, 3-aminopropyltriethoxysilane; ZIF-90, zeolitic imidazolate framework-90) membrane was developed to eliminate interfacial defects between PVA and ZIF-90 for enhanced ethanol dehydration performance, where APTES served as a covalently linked bridge to cross-link PVA and ZIF-90 simultaneously. The morphologies and physicochemical properties of the resultant membranes were characterized by various characterization techniques. Moreover, we also explored the effects of [ZIF-90]/[APTES] mole ratio and [ZIF-90]/[APTES] loading on the separation performance of the trinity membranes. The results indicated that ZIF-90 particles showed better dispersion and compatibility in PVA-APTES-ZIF-90 trinity membranes than in PVA/ZIF-90 hybrid membrane, attributed to the ternary cross-linking among PVA, APTES, and ZIF-90. Compared with pristine PVA membrane, PVA-APTES-ZIF-90 trinity membranes showed stronger anti-swelling and mechanical properties, as well as more excellent separation performance, which resulted from the incorporation of cross-linker APTES and ZIF-90 particles. The separation factor of the optimal PVA-APTES-ZIF-90 trinity membrane was improved by 215.4%, up to 552, accompanied by a total flux of 82 g/m 2 h. Ternary cross-linking among cross-linker, inorganic filler, and polymeric chain is therefore believed to be a feasible strategy in preparing polymeric-based hybrid membranes with high separation performance. Graphical abstract Summary: A novel ternary cross-linked hybrid membrane with APTES as co-cross-linkers of ZIF-90 and PVA for efficient ethanol dehydration
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2021
·Vol. 25
·期 5
·1541-1553
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IF 2.647
Zeng Laiyuan,Wei Xuefeng,Miao Juan,Zhang Ruichang,Zhang Jun,Zhou Ming,Lu Weiwei
A Sb-doped SnO 2 anode modified with Ni and B was fabricated by the sol–gel method. The effect of major operation parameters of electrode preparation, such as Ni content, B content, and calcination temperature, on the mineralization degree of phenol was investigated. Response surface methodology was used to optimize the experimental conditions and evaluate the association between various operation parameters. The morphology, crystal structure, and electrocatalytic performance of the prepared SnO 2 –Sb–Ni–B anodes were studied by scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), linear sweep voltammetry (LSV), and cyclic voltammetry (CV). The optimized sol–gel preparation ratio of citric acid, ethylene glycol, tin tetrachloride, antimony trichloride, nickel chloride, and boric acid was 650:200:100:6.5:0.5:2, and the calcination temperature of the electrode was 550 °C. The SnO 2 –Sb–Ni–B anode has the highest oxygen evolution potential of 1.63 V (vs. Hg 2 /Hg 2 SO 4 ). The removal degree of phenol reached 58% within 2 h on the SnO 2 –Sb–Ni–B anode. The accelerated lifetime of the selected SnO 2 –Ni–B anode was 720 min, which was carried out in a 3-mol/L sulfuric acid solution with a current density of 500 mA/cm 2 .
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JOURNAL OF POLYMERS AND THE ENVIRONMENT
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2021
·Vol. 30
·期 2
·653-665
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IF 3.667
Zheng Wenting,Kuchukulla Ratnakar Reddy,Xu Xiangning,Zhang Dandan,Zhou Lihong,Zeng Qingle
How to efficiently and economically remove heavy metals from sewage has been a huge challenge in the world. This article reports on an adsorbing material with comb-shaped chitosan–grafted polyethyleneimine dithiocarbamate (CC-GP-D), which is prepared by grafting polyethyleneimine on chitosan as main chain via glutaraldehyde, then reduce the generated C=N double bond using NaBH 4 , and finally functionalizing primary and secondary amino groups with CS 2 . This comb-shaped structure adsorbent material can better contact with heavy metal ions, so that it can absorb more heavy metal ions at a faster rate. This material is more green, environmentally friendly and economical with chitosan as the main chain. The material can effectively adsorb heavy metals in sewage, such as cadmium (II), copper (II), lead (II), nickel (II), and cobalt (II). After 80 min of adsorption, its adsorption capacity for cadmium (II), copper (II), lead (II), nickel (II), and cobalt (II) reached 178.7 mg/g, 138.9 mg/g, 337.7 mg/g, 109.2 mg/g, 157.6 mg/g respectively.
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Nanoscale Research Letters
·
2021
·Vol. 16
·期 1
·1-13
·
IF 4.703
An Li,Tao Qing,Wu Yue,Wang Nana,Liu Yan,Wang Feifei,Zhang Lixing,Shi Aihua,Zhou Xiumin,Yu Shuang,Zhang Jingzhong
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons in the midbrain, and the stem cell transplantation method provides a promising strategy for the treatment. In these studies, tracking the biological behaviors of the transplanted cells in vivo is essential for a basic understanding of stem cell function and evaluation of clinical effectiveness. In the present study, we developed a novel ultrasmall superparamagnetic iron oxide nanoparticles coating with the polyacrylic acid (PAA) and methoxypolyethylene glycol amine (PEG) by thermal decomposition method and a two-step modification. The USPIO-PAA/PEG NPs have a uniform diameter of 10.07 ± 0.55 nm and proper absorption peak of the corresponding ligands, as showed by TEM and FTIR. MTT showed that the survival of cells incubated with USPIO-PAA/PEG NPs remained above 96%. The synthesized USPIO-PAA/PEG had a good relaxation rate of 84.65 s −1 Mm −1 , indicating that they could be efficiently uptake and traced by MRI. Furthermore, the primary human adipose-derived stem cells (HADSCs) were characterized, labeled with USPIO-PAA/PEG and transplanted into the striatum of 6-hydroxydopamine (6-OHDA)-induced PD rat models. The labeled cells could be traced by MRI for up to 3 weeks after the transplantation surgery; moreover, transplantation with the labeled HADSCs significantly attenuated apomorphine-induced rotations in PD models and increased the number of the dopaminergic neurons in the substania nigra . Overall, the development of USPIO-PAA/PEG NPs provides a promising tool for in vivo tracing technique of cell therapy and identifies a novel strategy to track stem cells with therapeutic potential in PD.
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APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2021
·Vol. 127
·期 6
·1-10
·
IF 2.584
Liu Yurong,Niu Shaoyu,Hu Rong
In this work, the ferric cobalt sulfide/aminated graphene quantum dots (FeCo 2 S 4 /NH 2 -GQDs) nanoflowers grown on Ni foam substrate have been successfully fabricated via a facile two-step hydrothermal method. The as-prepared FeCo 2 S 4 /NH 2 -GQDs nanoflowers can expose plenty of electroactive sites, provide fast charge transfer paths and buffer the drastic volume change during long-term charge–discharge cycles. Therefore, the FeCo 2 S 4 /NH 2 -GQDs nanoflowers exhibit excellent supercapacitive performance, including high specific capacitance, excellent rate capability and cycling stability. The specific capacitance of FeCo 2 S 4 /NH 2 -GQDs composite electrode reaches 2314.8 and 1802.5 F g −1 at the current density of 1 and 10 A g −1 , respectively, while maintaining superior cycling stability with 95.1% capacitance retention after 5000 cycles. This study proves that NH 2 -GQDs are promising materials to enhance the electrochemical performance of bimetallic sulfides, providing a new insight for the design and fabrication of novel electrode materials for high-performance supercapacitors.
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Nature Communications
·
2021
·Vol. 12
·期 1
·1-12
·
IF 14.919
Chen Feng,Bai Min,Cao Xiaowen,Xue Jing,Zhao Yue,Wu Na,Wang Lei,Zhang Dexin,Zhao Yongxi
Exploring spatial organization and relationship of diverse biomolecules within cellular nanoenvironments is important to elucidate the fundamental processes of life. However, it remains methodologically challenging. Herein, we report a molecular recognition mechanism cellular macromolecules-tethered DNA walking indexing (Cell-TALKING) to probe the nanoenvironments containing diverse chromatin modifications. As an example, we characterize the nanoenvironments of three DNA modifications around one histone posttranslational modification (PTM). These DNA modifications in fixed cells are labeled with respective DNA barcoding probes, and then the PTM site is tethered with a DNA walking probe. Cell-TALKING can continuously produce cleavage records of any barcoding probes nearby the walking probe. New 3’-OH ends are generated on the cleaved barcoding probes to induce DNA amplification for downstream detections. Combining fluorescence imaging, we identify various combinatorial chromatin modifications and investigate their dynamic changes during cell cycles. We also explore the nanoenvironments in different cancer cell lines and clinical specimens. In principle, using high-throughput sequencing instead of fluorescence imaging may allow the detection of complex cellular nanoenvironments containing tens of biomolecules such as transcription factors.
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