Journal of Inorganic and Organometallic Polymers and Materials
·
2021
·Vol. 31
·期 5
·2054-2062
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IF 3.543
Huang Weihong,Si Haojie,Qing Yujie,Zhang Liming,Zhang Wenwen,Song Fei,Ni Xiaoni,Yang Wenming
A magnetic, core–shell structured pH-responsive molecularly imprinted polymer was prepared by surface imprinting technique and free radical polymerization for selective extraction of sulfamethoxazole. The imprinted polymer shell was prepared using 2-(Dimethylamino) ethyl methacrylate as pH-sensitive monomer, a certain amount of 4-vinylphenylbronic acid and methacrylic acid as common monomer to increase selectivity, sulfamethoxazole as template molecules. Excellent adsorption capacity (39.06 mg g −1 ) and selectivity (IF = 2.19) were achieved and the capture/release process can be regulated by pH value. In addition, it has been successfully applied to the detection of sulfamethoxazole in water samples and the recovery rate reached 96.2%. This study provides a new method and idea for the selective separation and detection of sulfamethoxazole in actual samples.
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MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 1
·1-12
·
IF 5.833
Wang Qin,Shi Yupeng,Chen Wandi,Yang Mo,Yi Changqing
A novel dual-functional nanoprobe was designed and synthesized by facile assembly of quinoline derivative (PEIQ) and meso-tetra (4-carboxyphenyl) porphine (TCPP) via electrostatic interaction for simultaneous sensing of fluorescence of Zn 2+ and pH. Under the single-wavelength excitation at 400 nm, this nanoprobe not only exhibits “OFF-ON” green fluorescence at 512 nm by specific PEIQ-Zn 2+ chelation, but also presents red fluorescence enhancement at 654 nm by H + -triggered TCPP release. The nanoprobe demonstrated excellent sensing performance with a good linear range (Zn 2+ , 1–40 μM; pH, 5.0–8.0), low detection limit (Zn 2+ , 0.88 μM), and simultaneous response towards Zn 2+ and pH in pure aqueous solution within 2 min. More importantly, this dual-functional nanoprobe demonstrates the capability of discerning cancerous cells from normal cells, as evidenced by the fact that cancerous HepG2 cells in tumor microenvironment exhibit substantially higher red fluorescence and significantly lower green fluorescence than normal HL-7702 cells. The simultaneous, real-time fluorescence imaging of multiple analytes in a living system could be significant for cell analysis and tracking, cancer diagnosis, and even fluorescence-guided surgery of tumors. Graphical abstract
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JOURNAL OF FOOD SCIENCE
·
2021
·Vol. 86
·期 3
·677-686
·
IF 3.167
Yuanyuan Chen,Yu Tang,Qiming Wang,Lin Lei,Jichun Zhao,Yuhao Zhang,Lin Li,Qiang Wang,Jian Ming
Absract The interaction between gluten and hydrocolloid additive, as well as the pH condition during dough formation is very important in making flour products. In this study, the influence of different pH conditions on the interactions between gluten proteins (including glutenin and gliadin) and carboxymethylcellulose (CMC), and on the rheological and microstructure changes of gluten proteins was investigated. The dynamic frequency sweep indicated CMC-gluten displayed more solid-like behavior under alkaline conditions than that under acidic conditions. The creep-recovery experiment suggested acidic conditions were not conducive to maintain the elasticity of CMC-gluten. Microstructural changes of various glutens with CMC showed that a higher ratio of β-sheets was observed in the CMC-gluten and CMC-glutenin under alkaline conditions. Total free sulfhydryl contents and changes in tryptophan microenvironment showed glutenin played a key role in the G polymerization with the addition of CMC. Lower surface hydrophobicity of CMC-gluten was displayed under acidic conditions. Scanning electron microscopy images showed that neutral and alkaline conditions were conducive to the network structure formation of CMC-gluten and CMC-glutenin. Practical Application This study investigated the interaction of CMC with gluten, gluten, and gliadin under different pH conditions, providing a basis for expanding dough quality improvement, and extending the in-depth application of CMC in the food industry.
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RSC Advances
·
2020
·Vol. 10
·期 69
·42423-42431
·
IF 3.119
Ruidong Luo,Jinfeng Dong,Yunbai Luo
We first synthesized a diblock copolymer poly[tert-butyl methacrylate]-b-poly[3-(trimethoxysilyl)propyl methacrylate] (PtBMA-b-PTMSPMA) through reversible addition–fragmentation chain transfer (RAFT) living radical polymerization and grafted it onto fumed silica by converting the PTMSPMA segment to silanol and the PtBMA segment to polymethylacrylic acid (PMAA) in the presence of trifluoroacetic acid in order to obtain PMAA brush-coated silica nanoaggregates P-Si. TEM, DLS, FTIR, and TGA results confirmed the successful modification of the starting materials. The nanoaggregates flocculated and stabilized a toluene-in-water Pickering emulsion at low pH, while the nanoaggregates were well dispersed in water and broke the emulsion under both neutral and basic conditions. Alternatively, the addition of acid/base induced emulsification/demulsification cycles that were sustained for several cycles. Moreover, when the P-Si was mixed with Rh-loaded silica, Rh-Si, the mixture had the same pH-responsive Pickering emulsion behavior as the single P-Si. This Pickering emulsion system can be used in the biphasic interfacial catalytic hydrogenation of olefins and had excellent yields under a hydrogen atmosphere. The yield of Pickering emulsion catalysis rapidly reached more than 99% in 3 h, while that of the demulsified mixture failed to reach 20% in 4 h, which verified the promotion of catalysis by the Pickering emulsion. Base-induced demulsification can be used to separate the products and recycle the catalyst. This pH-responsive Pickering emulsion catalytic system was capable of several cycles of reuse, and there was no significant decrease in catalytic efficiency even after eight cycles.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2020
·
IF 16.683
Sijin Zuo,Xuming Jin,Xinwei Wang,Yunhao Lu,Qi Zhu,Jiangwei Wang,Weiping Liu,Yonghua Du,Juan Wang
ABSTRACT Atomically dispersed heterogeneous metal catalysts are promising in dealing with the ever-growing environment and energy issues. However, the practical uses of such catalysts are challenged by the concerns of low reliability and reusability of current compositions under changeable conditions. Here we demonstrate a strategy to stabilize the atomically dispersed Fe catalysts through anchoring the Fe atoms in between a C 3 N 4 -rGO double-layered support. The layered structure is found to significantly prohibit acid leaching and agglomeration of Fe atoms while maintaining activity of the reaction sites, even under extreme pH conditions (pH < 3 or> 11). This allows us to realize high performance Fenton-like reaction via activation of persulfate with unforeseen reactive and recycling abilities over all pH values (0 to 14). This work offers opportunities for understanding the Fenton-like system at extreme reaction conditions, while providing keen insights into the development of stable atomic metal catalysts for practical use.
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RSC Advances
·
2020
·Vol. 10
·期 56
·33635-33641
·
IF 3.119
Meihua Lin,Xin Ma,Shijun Lin,Xiaojin Zhang,Yu Dai,Fan Xia
Carbon dots (CDs) as fluorescent probes have been widely exploited to detect biomarkers, however, tedious surface modification of CDs is generally required to achieve a relatively good detection ability. Here, we synthesized N-doped carbon dots (N-CDs) from triethylenetetramine (TETA) and m-phenylenediamine (m-PD) using a one-step hydrothermal method. When the pH increases from 3 to 11, the fluorescence intensity of the N-CDs gradually decreases. Furthermore, it displays a linear response to the physiological pH range of 5–8. Au3+ is reduced by amino groups on the surface of N-CDs to generate gold nanoparticles (AuNPs), causing fluorescence quenching of the N-CDs. If glutathione (GSH) is then added, the fluorescence of the N-CDs is recovered. The fluorescence intensity of the N-CDs is linearly correlated with the GSH concentration in the range of 50–400 μM with a limit of detection (LOD) of 7.83 μM. The fluorescence probe was used to distinguish cancer cells from normal cells using pH and to evaluate intracellular GSH. This work expands the application of CDs in multicomponent detection and provides a facile fluorescent probe for the detection of intracellular pH and GSH.
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AAPS PHARMSCITECH
·
2020
·Vol. 21
·期 7
·1-11
·
IF 2.401
Ma Qun,Luo Rui,Zhang Huimin,Dai Manman,Bai Luyu,Fei Qingsong,Lei Fang,He Ning
We developed a pH-triggered in situ gel (ISG) for ocular delivery of vinpocetine to achieve systemic absorption and a brain-targeting effect in rats. Carbopol acted as a gelling agent combined with hydroxypropyl methylcellulose (HPMC) as a viscosity-enhancing agent. The concentration of Carbopol (0.2%, w/v) and HPMC (1.5%, w/v) was optimized for the ISG system. The optimized formulation was evaluated for studies on release in vitro , rheology, differential scanning calorimetry, ocular irritation, residence time, and in vivo pharmacokinetics. The vinpocetine ISG stayed longer in rabbit eyes than vinpocetine ointment. In vivo pharmacokinetics showed that compared with vinpocetine ointment, vinpocetine ISG attained a peak plasma concentration and area under the curve that was 1–2 folds greater in rat plasma. The Drug Targeting Index (DTI) was 1.06 and 1.26 for vinpocetine ointment and vinpocetine ISG, respectively, after ocular administration, showing that vinpocetine ISG had better distribution in rat brain. These results revealed that a pH-triggered ISG system via ocular administration could be an alternative approach compared with traditional ophthalmic formulations.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2020
·Vol. 137
·期 41
·49250
·
IF 2.52
Ya Li,Cui Cheng,Xiaoran Gao,Siyuan Wang,Hanhui Ye,Xiao Han
Despite aminoglycosides (AGs) have superior antibacterial ability, all approved AGs by FDA are associated with adverse effects such as ototoxicity and nephrotoxicity. To solve these problems, AGs hydrogels based on dynamic covalent bond cross-linking were quickly prepared within 25 s by using AGs, aldehyde hyaluronic acid (A-HA), and adipic acid dihydrazide graft hyaluronic acid (HA-ADH) as materials. FT-IR, thermal analysis, and SEM results exhibited that A-HA/HA-ADH/AGs hydrogels were successfully synthesized with highly porous and interconnected network structure. The water absorption ratio of the hydrogels increased with the decreasing pH and temperature, indicating the hydrogels were pH- and temp-responsive. The pH-dependent degradation also demonstrated pH sensitivity of the hydrogels. Rheology and self-healing analysis assessment displayed that AGs hydrogels had good mechanical property, self-healing ability, and injectability. The hydrogels had no cytotoxicity to L929 cells and their hemolysis ratios were between 0.7% and 1.3%, which reached a nontoxic level. Most importantly, inhibition zones results demonstrated that the hydrogels had excellent and sustained antibacterial performance against Escherichia coli and Staphylococcus aureus . Therefore, A-HA/HA-ADH/AGs hydrogels are potential dressings for wound healing. Further plans including antibacterial and in vivo wound healing assays will be shown in the next work.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 14
·16963-16971
·
IF 3.056
Gong Pijian,Li Chunyu,Li Xinxue
Marine diesel engines produce a lot of exhaust gas (NO, SO 2 ). Based on the situation that wet scrubbing methods have been already applied to ship desulfurization and seawater is easily accessible around the ships, this paper proposed a novel AOP (advanced oxidation process) of NaClO 2 (sodium chlorite) with Cl − (abundant Cl − exist in seawater) to remove NO from the flue gases of marine engines. The buffer capacity of NaAC (sodium acetate), the effect of Cl − concentration, and Cl − promotion mechanism on NO removal were investigated. The result showed that the existence of NaAC in solution could inhibit the rapid decline of the solution pH. The addition of Cl − achieved a remarkable promotion to NO removal at lower NaClO 2 concentration, which was due to the fast generation of ClO 2 from the promotion decomposition of NaClO 2 by Cl − in acidic condition. Then, the thermodynamic and dynamic mechanism of the generation of ClO 2 was intensively analyzed. And the mechanism of NO removal was discussed finally.
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SN Applied Sciences
·
2020
·Vol. 2
·期 3
·1-10
·
IF 0
Jia Shuyue,Wang Qidong,Peng Jing,Gao Jingru,Tang Dongyan
ZnO nanomaterials have been widely studied in medical and biological fields owing to their better biocompatibility, pH-responsibility and higher photocatalytic ability as drug carriers and disease therapy agent. However, the unstability of ZnO nanomaterials within aqueous solution restricts the applications of it to some extent. In this work, ZnO nanofibers with relative higher porosity were fabricated by electrospinning to improve the load capacity as carriers, and then were modified by hydrophobic poly(methyl methacrylate) (PMMA) through graft polymerization on the surface to improve their stability in aqueous solution. Observations on the morphologies of the nanofibers by SEM showed that the surface modification of PMMA well enhanced the water-stability of ZnO nanofibers. Moreover, the photocatalytic degradation of Rhodamine B was investigated, and pH sensitive release behaviors were studied in details under different pH values, by taking Nifedipine as drug model. The results indicated that PMMA modified ZnO nanofibers showed obvious photocatalytic performances and maintained relative excellent pH-response properties. These findings all suggested that the modified ZnO nanofibers might be one kind of excellent material as medical carrier or therapy agents.
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APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Kui Xu,Mi Zhou,Ming Li,Weizhen Chen,Yabin Zhu,Kaiyong Cai
Titanium (Ti)-based implants have to undergo many severe ordeals under the complex in vivo microenvironments, which makes greater demands on the biological function of their surfaces. As a result, it is particularly important to develop the intelligent surfaces of Ti-based implants. In this study, metal-phenolic networks (MPNs) were prepared on pure Ti surfaces to achieve the pH-controlled release of bioactive divalent metal ions ( e.g. , Sr 2+ , Cu 2+ , Zn 2+ , and Mn 2+ ). The practical potential of MPNs-based coatings in biomedical applications was further highlighted by the controllable release amount and species of metal ions. MPNs coated Ti surfaces displayed excellent biological properties, including enhanced protein adsorption, good biocompatibility as well as the promoted adhesion and proliferation of mesenchymal stem cells (MSCs). What’s more, a continuous release of bioactive divalent metal ions ( e.g. , Sr 2+ and/or Cu 2+ ) significantly accelerated the osteogenic differentiation of MSCs. The surface modification method based on MPNs provides an extremely feasible solution for preparing Ti-based implants that can adapt to different in vivo microenvironments.
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JOURNAL OF MOLECULAR LIQUIDS
·
2020
·
IF 5.065
Xinyu Zheng,Huaili Zheng,Rui Zhao,Zikang Xiong,Yili Wang,Yongjun Sun,Wei Ding
In order to deal with the increasingly serious water pollution caused by dye wastewater, a novel sulfonic acid-modified polyacrylamide magnetic composite (Fe 3 O 4 @SiO 2 /P(AM-AMPS)) was facilely prepared by crosslink reaction. The physicochemical properties and adsorption performances of Fe 3 O 4 @SiO 2 /P(AM-AMPS) were systematically studied by different characterization techniques and a series of batch experiments, respectively. It was found that the adsorption capacities of Fe 3 O 4 @SiO 2 /P(AM-AMPS) towards cationic dyes crystal violet (CV) and methylene blue (MB) were largely enhanced than those of silica-coated Fe 3 O 4 (Fe 3 O 4 @SiO 2 ) and maintained at relatively high levels in a wide pH range, due to the three-dimensional network structure and abundant functional groups of modified polyacrylamide. Besides, owing to the introduction of Fe 3 O 4 @SiO 2 , Fe 3 O 4 @SiO 2 /P(AM-AMPS) presented a unique magnetic property that helped it to be rapidly separated from water in a magnetic field. The maximum adsorption capacities of Fe 3 O 4 @SiO 2 /P(AM-AMPS) were 2106.37 mg g −1 for CV removal and 1462.34 mg g −1 for MB removal at 298.15 K, much higher than those of other reported magnetic composites. Furthermore, Fe 3 O 4 @SiO 2 /P(AM-AMPS) was effectively regenerated with HCl solution and the regeneration rates were higher than 97% and 80% for CV and MB removal after five adsorption-desorption cycles, respectively. With its excellent adsorption capacity, wide pH applicability, high separation speed, and satisfactory regeneration ability, Fe 3 O 4 @SiO 2 /P(AM-AMPS) was expected to become a promising adsorbent in the purification of cationic dye wastewater.
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