POLYMER
·
2022
·
IF 4.432
Hui Wang,Chongrui Zhang,Lusha Jiang,Shan Tong,Yu-Chao Li,Hefu Pu,Qiang Zhao
Calcium bentonites (CaB), rich in European and Asian countries, are potential barrier materials for landfill leachate containment. However, CaB has to be converted into sodium bentonite (NaB) by Na-activation so as to facilitate intercalation modification. In this study, salt-resistant poly(acrylic acid-N, N-diethyl acrylamide) [P(AA-DEA)] was designed to intercalate and graft CaB by in situ polymerization without prior Na-activation. By this design, acrylic acid monomers were first adsorbed into interlayers of Ca-montmorillonite (Ca-MT) through the electrostatic complexation with Ca 2+ , dislodging Ca 2+ from montmorillonite surfaces. Then, ammonium ions of N, N-diethyl acrylamide were adsorbed into Ca-MT interlayers. Swelling index of the obtained CaB/P(AA-DEA) nanocomposite in aggressive coal combustion product (CCP) leachate is 15.8 mL/2g, which is as high as 3.4 times that of CaB. CaB/P(AA-DEA)-based geosynthetic clay liners (GCLs) exhibit very low hydraulic conductivity (1.6✕10 −12 m/s) to CCP leachate, which is as low as 3.3% that of the U.S. standard requirement and ∼4 orders of magnitude lower than that of CaB-based GCL. Polymer elution of CaB/P(AA-DEA)-8% in CCP leachate is as low as 1.9% that of the dry mixed samples.
研究领域:
环境工程
·
材料科学
·
土木工程
·
高分子化学
·
地质屏障材料
✓ 已验证
DOI
高影响因子
MATERIALS SCIENCE FORUM
·
2016
·
IF 0
Xiu Ju Wang,Xin Lian Shi,Shu Fang Hou,Jian Hua Yang,Kai Li Zhou,Zhong Peng Wang,Li Guo Wang
In this paper, a novel nanocomposite forward osmosis membrane (nTiO2-CTA/CA) was fabricated by introducing nanotitaniumdi oxide (nTiO2) into the cellulose triacetate/cellulose acetate (CTA/CA)-based casting solution using phase inversion methods. Casting composite and preparation--nTiO2 content, blend temperature and coagulating bath temperature--were tested for their effects on pure water flux and salt rejection of membranes. Results revealed that the FO membrane prepared under optimized composition showed excellent desalination performance (high water flux = 5.38 L/m2·h and salt rejection > 97 %). Moreover, SEM images showed that addition of nTiO2 resulted in nanocomposite forward osmosis membrane with a smoother surface. The contact angle of the membranes decreased from 76o to 51° with increase nTiO2 concentration from 0% to 0.10%.
研究领域:
膜科学
·
水处理技术
·
材料科学
·
纳米技术
·
环境工程
✓ 已验证
DOI
ENERGY & FUELS
·
2024
·
IF 5.2
Jinchen Ma,Yingjie Mi,Fan Wang,Chaohe Zheng,Haodong Huang,Haibo Zhao
In the chemical looping combustion of chlorine-rich biomass or coal, a trace element, chlorine, will cause serious corrosion of oxygen carriers and heat exchange equipment in boilers. To address this issue, we design Ca- and Ba-decorated oxygen carriers to achieve two goals: on one hand, reducing the concentration of chlorine-containing gases by in situ dechlorination; on the other hand, employing protective materials to preferentially bind with gaseous chlorine to safeguard the active components of the oxygen carriers. Carefully designed experiments are conducted under simplified experimental conditions using 50 ppmv HCl-containing CH4 to evaluate the intrinsic characteristics of oxygen carriers in terms of dechlorination efficiency and reactivity. The results demonstrate that both the reaction performance and the chlorine-resistance performance of Ca–Cu and Ba–Cu composite oxygen carriers are significantly improved. This is because (a) Ca and Ba preferentially form chlorides with HCl, effectively shielding the active Cu component of the oxygen carrier from chlorine poisoning and (b) the specific surface area and pores of Ca/Ba-decorated oxygen carriers are increased, which not only strengthens the heterogeneous reaction between oxygen carrier and combustible gas but also improves the chemical looping combustion performance. The Cl-resistant oxygen carriers, Ca–Cu and Ba–Cu, emerge as promising candidates for the chemical looping combustion of fuels with high chlorine content.
研究领域:
能源化学
·
材料科学
·
环境工程
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Wenjia Yang,Wen Cui,Lin Yang,Guo Zhang,Xiaofang Li,Yu Shen,Fan Dong,Yanjuan Sun
Considering that the structural differences could dictate the photocatalytic efficiency, the cubic SrTiO 3 (STO) and tetragonal CaTiO 3 (CTO) were developed to illustrate the structure–activity relationship. The STO with cubic structure demonstrates much higher photocatalytic toluene removal efficiency ( ca. 80.0%) than that of CTO ( ca. 20.0%), which can be ascribed to boosted formation of reactive oxygen species (ROS), increased selectivity of intermediates, and promoted ring-opening and mineralization rate. Combining theoretical simulation and experimental characterization, the results reveal that the O 2 and H 2 O molecules tend to be adsorbed on the cubic STO, which boosts the formation of ROS. Also, highly selective formation of intermediate (benzoic acid) has been realized to accelerate ring-open and mineralization process as evidenced by the smooth conversion of STO as indicated by Gibbs free energy. This work provides new perspectives on the understanding of relationship between intrinsic structure and photocatalytic performance.
研究领域:
材料科学
·
环境科学
·
催化
·
化学工程
✓ 已验证
DOI
高影响因子
Processes
·
2026
·Vol. 14
·期 8
·1258
·
IF 3.4
Guiping Liao,Hongmei Tang,Jiayan Wu,Quanyun Ye,Yihao Li,Zhongbo Shang,Leiye Sun,Pingxiao Wu
Schwertmannite (Sch) is a widespread iron oxyhydroxysulfate mineral in acid mine drainage (AMD) systems, and its transformation strongly influences the environmental fate of chromium (Cr). However, the role of Ca(II), which is commonly introduced during alkaline neutralization of AMD, in regulating the transformation of Cr(VI)-adsorbed schwertmannite (Cr-Sch) and subsequent Cr redistribution remains insufficiently understood. In this study, transformation experiments were conducted under various pH conditions (3.0, 7.0, and 10.0) to investigate the effects of Ca(II) speciation on mineral transformation and Cr behavior. The results demonstrated that the transformation of Cr-Sch was predominantly pH-dependent. Under acidic conditions, Cr-Sch transformed into goethite via dissolution–recrystallization, resulting in transient Cr release followed by partial refixation. The presence of Ca(II) exerted only a minor influence due to weak interactions between Ca2+and positively charged mineral surfaces. Under alkaline conditions, Cr-Sch preferentially transformed into hematite through dehydroxylation and cation rearrangement, leading to the sustained release of adsorbed Cr(VI). In contrast, Ca(II) predominantly precipitated as CaCO3precipitate (calcite, aragonite, and vaterite) under alkaline conditions, which coated mineral surfaces and inhibited phase transformation and Cr release. These findings reveal that Ca(II) regulates Cr redistribution primarily through pH-dependent speciation and mineral–surface interactions, highlighting coupled geochemical processes governing iron mineral transformation and contaminant mobility in AMD environments. This study provides mechanistic insights for predicting Cr behavior and optimizing alkaline remediation strategies in mining-impacted systems.
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2026
·
IF 3
Jiajia Wang,Chun Kan,Demeng Qian,Mingping Gao,Ayang Zhou,Bao-Kang Jin
CA-125, as a tumor marker for ovarian cancer, plays an importance role for rapid and sensitive detection in early diagnosis. Herein, a label-free electrochemical immunosensor based on COF/PTh/MB nanocomposite was constructed for the detection of CA-125.The TAPB-DMTP-COF material, with its large surface area and stable porous framework, was used as the substrate. However, its poor conductivity hindered electron transfer. To address this, conductive polymer PTh was combined with the COF to enhance the composite's conductivity. Meanwhile, MB was used as a signal probe, and differential pulse voltammetry (DPV) was adopted to measure the electrochemical signal. Under optimized experimental conditions, the proposed immunosensor exhibited excellent performance for the CA-125 detection, with a detection range of 1 mU/mL-10000 mU/mL, and a low detection limit of 0.34 mU/mL (S/N = 3), providing a potential platform for clinical application.
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Kaiwen Ma,Jian Sun,Rongyue Sun,Chuanwen Zhao
Lately, Ca-based sorbents with a core–shell structure have been effectively produced to augment the sorbent’s capabilities. However, modifying the pristine core of Ca-based pellets with a core–shell structure notably influences the performance of the synthesized sorbent, and research in this domain remains scarce. Here, two categories of Al-stabilized, Ca-based pristine cores were produced using Ca(OH) 2 mixed with Al-based stabilizer precursors of insoluble aluminum oxide and soluble aluminum nitrate, respectively, through the extrusion-spheronization technique. Due to the impact of mechanical extrusion, soluble aluminum nitrate can accumulate in-homogeneously in the Ca-based pristine core, leading to its expansion and rupture during the high-temperature calcination stage because of the decomposition of aluminum nitrate. The oxide-form aluminum stabilizer precursor can be uniformly distributed throughout the Ca-based pristine core pellets, demonstrating notably superior cyclic CO 2 sorption capability and mechanical strength. The Al-fortified, core–shell structured Ca-based sorbent pellets demonstrated a peak CaO carbonation conversion rate of 54.8 % after 100 cycles when the Ca:Al molar ratio was precisely set to 85:15, which is about 2.1 times higher compared to the core–shell Ca-based sorbent pellets composed of a pure CaO core. This is primarily due to the formation of an evenly distributed inert Ca 12 Al 14 O 33 within the pristine core, which effectively reduces high-temperature sintering. Hence, core–shell Ca-based sorbent pellet assembled with an Al-stabilized pristine core, could be a promising candidate for application in the CaL process for CO 2 capture.
研究领域:
材料科学
·
环境工程
✓ 已验证
DOI
高影响因子
PHYTOMEDICINE
·
2025
·
IF 8.3
Shuhui Lei,Kaiqun Liu,Cong Liu,Ran An,Zilu Bao,Huan Zhang,Min Zou,Jianqiu Chen,HuiHui Zhang,Liangkai Wei,Zhou Lan,Lvyi Chen
s Background Inflammation is a vital biological defense mechanism, yet uncontrolled or prolonged inflammation can cause tissue damage. The NLRP3 inflammasome, a central component of innate immunity, drives inflammation by activating caspase-1 and promoting the release of cytokines like IL-1β. Monosodium urate (MSU) crystals are potent NLRP3 inflammasome activators implicated in diseases such as gout. While resveratrol, a natural polyphenol, exhibits anti-inflammatory properties, the specific mechanisms by which its cis-isomer (Cis-Resv) inhibits NLRP3 inflammasome activation remain poorly understood. Purpose This study aims to investigate the inhibitory effect of Cis-Resv on MSU-induced NLRP3 inflammasome activation and elucidate the underlying molecular mechanisms. Methods Bone marrow-derived macrophages (BMDMs) from C57BL/6J mice were stimulated with MSU crystals. The effects of Cis-Resv on IL-1β secretion, caspase-1 activation, and ASC oligomerization were evaluated using ELISA, Western blot, and immunoprecipitation, respectively. Transcriptomic analysis was employed to identify potential signaling pathways involved. The in vivo efficacy of Cis-Resv was assessed in MSU-induced acute gouty arthritis and air-pouch models by measuring joint swelling, inflammatory cytokines levels, and histopathological changes. Results Cis-Resv significantly inhibited MSU-induced NLRP3 inflammasome activation in BMDMs, reducing caspase-1 activation, IL-1β secretion, andassociated pyroptosis. Furthermore, Cis-Resv impeded ASC oligomerization, a critical step in inflammasome assembly. Transcriptomic analysis and subsequent functional validation revealed that Cis-Resv exerts these effects primarily through the TRPV4-Ca²⁺-phagocytosis-ROS signaling axis. Specifically, Cis-Resv inhibited macrophage TRPV4 channel activity, leading to decreased Ca²⁺ influx, impaired MSU crystal phagocytosis, and attenuated reactive oxygen species (ROS) accumulation. This reduction in ROS modulated the ROS-TXNIP pathway, diminishing the interaction between TXNIP and NLRP3, thereby suppressing inflammasome activation. In vivo , Cis-Resv effectively alleviated MSU-induced joint swelling, lowered IL-1β and TNF-α levels, and ameliorated histopathological damage in both gouty arthritis and air-pouch models. Conclusion Cis-Resv suppresses MSU-induced NLRP3 inflammasome activation by targeting the TRPV4-Ca²⁺-phagocytosis-ROS axis. This study identifies a novel mechanism and suggests Cis-Resv as a potential therapeutic agent for NLRP3-driven inflammatory conditions like gout.
研究领域:
免疫学
·
炎症研究
·
药理学
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Chengxiang Yang,Tingting Gou,Haoyu Wang,Qi You,Wenwei Lai,Yue Wang,Zhihao Du,Zhaobin Tang,Wei Liu,Xuchuan Jiang
Narrow-band red phosphors excited by blue light are vital for high-color-rendering lighting and wide-color-gamut displays. Nevertheless, the commonly utilized red phosphors exhibit considerable deficiencies in hydrothermal stability and color purity, thus constraining their practical usage. In this study, by using a developed doping strategy with Ca 2+ to regulate a local crystal field and the possible preferential occupation behavior of the Sr 2 YNbO 6 :Eu 3+ red phosphor with a double perovskite structure, it is found that their luminescence intensity and thermal stability are significantly enhanced. High-resolution scanning transmission electron microscope (STEM) measurements equipped with an aberration corrector revealed that Eu 3+ occupied the Sr 2+ or Y 3+ sites, forming two emission centers. This resulted in significant changes in the emission intensity at 594 nm and 611 nm with changes in the excitation wavelength. Furthermore, the introduction of Ca 2+ can increase the proportion of Eu 3+ at the Sr 2+ site, thereby enhancing the emission of the 5 D 0 → 7 F 2 transition at 611 nm. Meanwhile, we have significantly improved the color purity and thermal stability of the obtained red phosphors. The current findings reveal the site-selective luminescence mechanism in Eu 3+ -activated double perovskite structures and propose a cation substitution strategy to optimize excitation and emission simultaneously. This approach may provide an effective pathway for the design of high-performance red phosphors for advanced optoelectronic applications.
研究领域:
材料科学
·
发光材料
·
无机化学
·
固态化学
·
光学材料
·
功能材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENERGY & FUELS
·
2025
·
IF 5.3
Fang Wang,Xueyan Wu,Yuxuan Han,Yan Lv,Jixi Guo,Xiaoman Li,Yaping Zhang
In cement kiln flue gas emissions, high concentrations of alkali and alkaline earth metals cause the deactivation of the NbCe/Ti catalysts, significantly reducing their operational lifespan under industrial conditions. Here, the NbCe-loaded titanium nanotubes (NbCe/TiNTs) catalyst has been synthesized via hydrothermal and impregnation methods. The NbCe/TiNTs catalyst exhibits superior resistance to potassium (K) and calcium (Ca) poisoning. Notably, NbCe/TiNTs catalyst maintains high NOx conversion across a wide temperature range (192–350 °C). The 5Ca-NbCe/TiNTs and 3K-NbCe/TiNTs catalysts achieve a 90% NOx conversion at 235 and 242 °C, respectively, demonstrating remarkable resistance to K and Ca poisoning. The results indicate that TiNTs supports enhance both the specific surface area and surface acid sites of the catalyst, synergistically improving its resistance to K and Ca poisoning. Furthermore, an in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) study elucidates selective catalytic reduction with the NH3 (NH3-SCR) reaction mechanism, revealing dual contributions from both the Eley–Rideal (E–R) and Langmuir–Hinshelwood (L–H) mechanisms on the catalyst. This work provides a research direction for enhancing the alkali poisoning resistance of NOx removal catalysts.
研究领域:
环境催化
·
材料科学
·
化学工程
·
表面科学
✓ 已验证
产品关联
DOI
高影响因子
Acta Metallurgica Sinica-English Letters
·
2024
·Vol. 37
·期 7
·1147-1160
·
IF 2.9
Cheng Bishan,Li Depeng,Xing Baikang,Hou Ruiqing,Jiang Pingli,Zhu Shijie,Guan Shaokang
Magnesium and its alloys have attracting rising attention as one of biodegradable metallic materials. However, the rapid corrosion and severe localized corrosion still hinder their extensive applications in clinics. In this study, micro-alloying of Ca (≤ 0.1 wt%) into Mg0.5Zn0.2Ge alloy developed in our previous work was explored to further enhance the corrosion resistance and alleviate the localized corrosion of the alloy. The results reveal that the addition of Ca leads to the transformation of the cathodic Mg 2 Ge phase in Mg0.5Zn0.2Ca alloy into anodic MgCaGe phase in Ca-containing alloys, thereby changing the galvanic couples in alloys during immersion. The preferential dissolution of MgCaGe phase promotes the participation of Ca and Ge into the formation of corrosion products, resulting in the enrichment of Ca and Ge in the outmost of corrosion product layer, which stabilizes and passivates the corrosion product layer on Mg alloy surface. Additionally, the enrichment of Zn at the corrosion interface seems to further hinder the corrosion of Mg matrix. All of these factors confer a slower and more uniform corrosion on Mg0.5Zn0.2Ge x Ca ( x < 0.1 wt%) alloy, which provides favorable candidates for the further processing to gain suitable biodegradable Mg alloys.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Nanomedicine
·
2025
·
IF 6.5
Yilu Zheng,Gareth R Williams,Ran Hu,Sen Tong,Jianxiang Xu,Tong Wang,Yanyan Zhang,Junzi Wu,Fan Li,Yingyu Cai,Li-Min Zhu
Background: The development of selective formulations able to target and kill tumor cells without the application of external energy has shown great promise for anti-tumor therapy.Methods: Here, we report a “nanobomb” that explosively increases Ca content within cells. It can selectively release Ca2+ and generate H2O2 in the tumor microenvironment (TME) by acid-triggered degradation of the two-layer protective shell (ie, unlocking the “double-lock”). This material, termed CaO2@ZIF8:CUR@PAA, comprises a CaO2 core coated with the ZIF-8 framework, which was then loaded with curcumin (CUR) and coated again with polyacrylic acid (PAA).Results: Under the slightly acidic conditions of the TME, the PAA shell (first lock) breaks down first exposing CaO2@ZIF8 and CUR inside the cell. Then, ZIF8 (second lock) is degraded in response to acid to deposit Ca2+, and H2O2. CUR can promote the release of Ca2+ from the endoplasmic reticulum to the cytoplasm, inhibit the outflow of Ca2+, and accumulates a large amount of Ca2+ intracellularly together with exogenous Ca2+ (calcium storms). The powerful calcium storm that causes mitochondrial dysfunction. The presence of a large amount of exogenous H2O2 causes further oxidative damage to tumor cell membranes and mitochondria where intracellular ROS production far exceeds clearance. CaO2@ZIF8:CUR@PAA NPs can induce cell S cycle arrest and apoptosis to inhibit tumor multiplication and growth. Oxidative damage-triggered immunogenic cell death (ICD) in turn leads to the polarization of macrophages to the M1 phenotype, inducing immunogenic cell death and inhibiting tumor cell proliferation and metastasis.Discussion: The acid two-step unlocking nanoplatform is a therapeutic modality that combines calcium storm and oxidative damage. The mode triggers apoptosis leading to ICD of tumor cells. The material induces cycle blockade during treatment to inhibit cell proliferation. Robust in vitro and in vivo data demonstrate the efficacy of this approach and CaO2@ZIF8:CUR@PAA as an anticancer platform, paving the way for nanomaterials in immune-triggered cancer therapy.Highlights: - A new calcium accumulation nanoplatform plays a role in activate antitumor immunity.- Double-locked structure slows down the premature decomposition of CaO2.- The platform allows Ca2+ and H2O2 to accumulate in tumor cells.- This leads to mitochondrial dysfunction, apoptosis, and M1 macrophage polarization.- Potent anti-tumor effects are seen both in vitro and in vivo.
研究领域:
癌症治疗
·
纳米技术
·
免疫学
·
细胞生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）