ACS Applied Materials & Interfaces
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2016
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IF 7.145
Xueli Sun,Zhiyong Qian,Lingqiong Luo,Qipeng Yuan,Ximin Guo,Lei Tao,Yen Wei,Xing Wang
Poly(methyl methacrylate) (PMMA) is a widely used biomaterial. But there is still a challenge facing its unwanted bacterial adhesion because the subsequent biofilm formation usually leads to failure of related implants. Herein, we present a borneol-modified PMMA based on a facile and effective stereochemical strategy, generating antibacterial copolymer named as P(MMA-co-BA). It was synthesized by free radical polymerization and studied with different ratio between methyl methacrylate (MMA) and borneol acrylate (BA) monomers. NMR, GPC, and EA, etc., were used to confirm their chemical features. Their films were challenged with Escherichia coli (Gram-negative) and Bacillus subtilis (Gram-positive), showing a BA content dependent antibacterial performance. The minimum effective dose should be 10%. Then in vivo subcutaneous implantations in mice demonstrated their biocompatibilities through routine histotomy and HE staining. Therefore, P(MMA-co-BA)s not only exhibited their unique antibacterial character but also suggested a potential for the safe usage of borneol-modified PMMA frame and devices for further implantation.
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ACS Applied Materials & Interfaces
·
2017
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IF 7.504
Xiaoxia Le,Wei Lu,He Xiao,Li Wang,Chunxin Ma,Jiawei Zhang,Youju Huang,Tao Chen
Poor, nontunable mechanical properties as well as finite shape memory performance pose a barrier to shape memory hydrogels to realize practical applications. Here, a new shape memory hydrogel with tunable mechanical properties and multishape memory effect was presented. Three programmable reversible systems including PBA-diol ester bonds, AAc-Fe3+, and coil–helix transition of agar were applied to memorize temporary shapes and endow the hydrogel with outstanding multishape memory functionalities. Moreover, through changing the cross-linking densities, the mechanical properties of the as-prepared hydrogel can be adjusted.
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Materials Science & Engineering C-Materials for Biological Applications
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2017
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IF 4.164
Yahui Song,Jianping Gao,Xiaoyang Xu,Huilin Zhao,Ruinan Xue,Jingkuo Zhou,Wei Hong,Haixia Qiu
Thermal sensitive supramolecular hybrid gels for injectable drug release were prepared by adding different amounts of agar into folic acid (FA) gelator. The gelation temperature was modulated in order to form injectable gel with body temperature (37 °C). Such kind of folic acid-agar (FAG) hybrid gel makes it possible to use supramolecular gel as injectable drug loaded gels for drug release. FT-IR and UV–vis spectra indicate that agar macromolecules involve in the self-assembly process through intermolecular H-bonding and π-π stacking interactions with FA molecules. The SEM and TEM images demonstrate that the fiber diameter of FAG hybrid gel is about 20 nm, much smaller than that of FA gel (40 nm). However, FAG hybrid has a denser nano-fibrous network structure than FA gels. Moreover, FAG hybrid gel is endowed with a more ordered network structure and a little better crystallization capability by adding agar. FAG hybrid gel also shows a shear-thinning behavior but the shear viscosity is about 2 times higher than that of FA gel. Compared with FA gel, the storage (G′) and loss (G″) moduli of the FAG gel are higher, which implies an enhanced gel strength. At the same time, both FA and FAG gels are facilely affected by some external factors such as acid, base and salts. In acidic or basic conditions, the strength became weak and the gelation temperature (Tg) decreased. While, within certain concentrations, the salt (NaCl) increased the gel strength and Tg. FAG gel suffered lower mass loss and owned better stability in different pH solutions compared with pure FA gel. The release behavior of the FA and injectable FAG gels was investigated by using Rhodamine B as a mimic model drug. FAG hybrid gel shows a long release profile and the release time is 3 times longer than that of FA gel, up to 30 h, and the accumulative release amount reaches about 86%. So it is a potential injectable gel for sustained release drug delivery system.
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ADVANCED FUNCTIONAL MATERIALS
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2024
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IF 18.5
Qianjie Niu,Jiwei Jiang,Changsong Zhan,Yujie Tao,Zijun Ye,Jian Huang,Bin Dong,Zhenhui Kang
With the world's population expanding rapidly, modern agriculture is evolving at a swift pace, leading to a significant increase in food production, primarily through the use of chemical fertilizers. However, this heavy reliance on fertilizers has led to issues such as soil compaction and decrease of earthworm abundance. Herein this study reports a smart soil consisting of conventional soil and carbon dots (CDot) based smart material which is capable of automatically adjusting its porosity and soil aggregate size. Due to the responsiveness, The CDot-based smart soil can lift its height up to 150% upon humidity stimulation due to the increased porosity which is similar to the effect caused by earthworms. Based on this effect, this smart soil can increase the growth rate of maize seedlings by 40%, thus showing great potentials in agriculture.
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CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Yuyang Yao,Yueyue Lu,Yuan Li,Yanjing Ma,Edison Huixiang Ang,Jingwen Xu,Heda Ding,Yuna Shi,Yitao Chen,Junbin Liao,Zhenlu Shen,Jiangnan Shen
Strengthened surface modification via bio-safety and eco-friendly agent requirements, and the development of the antibacterial anion exchange membrane (AEM) has become crucial for resource recovery with water-sustainable management to effectively mitigate bacteria-related fouling control. A synergistic antibacterial system of lysozyme and tetrakis(hydroxymethyl)phosphonium sulfate (THPS) is explored here that is immobilized onto the surface of commercial AEM with L-dopa. Compared to the single biomacromolecule lysozyme, THPS performs a vital role in this functional layer by compensating for the insensitivity of the lysozyme to typical Gram-negative bacteria (Such as E. coli ). This system demonstrated excellent antibacterial performance ( E. coli and S. aureus were selected as test strains) according to the “contact-sterilization”, and the change with contact time was systematically investigated. Based on confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) examination of live and dead bacteria, it was showed that the as-modified membranes by synergistic antibacterial mechanism revealed effective inhibition of biofilm growth. Moreover, these modified layers demonstrated high stability in electrodialysis (ED) desalination systems. The bio-friendly and robust anti-biofouling characteristics of this approach offer valuable insights for constructing antibacterial surfaces in similar applications.
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CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Kaijun Xie,Xin Liu,Baichuan Mo,Tingting Li,Kai Xia,Long Fang,Yihui Zou,Dongjiang Yang,Xiaodong Zhang
Gel polymer electrolytes (GPEs) have attracted much attention due to their excellent flexibility, good interface contact, and high safety in solid-state supercapacitors (SSCs). However, in practical applications, GPEs still face low ionic conductivity and poor mechanical strength. This study delineates a novel dual-cationic Kgu/PAM GPE, the ion diffusion coefficients in which are 1.51 × 10 -8 cm 2 s −1 (K + ) and 4.77 × 10 -9 cm 2 s −1 (Na + ), respectively. Radial distribution function and in-situ Fourier transform infrared spectroscopy have confirmed that the migration mechanism of dual-cations in Kgu/PAM is through the long-range hydration channels, which is depended on the continuous formation of binding water facilitated by movement of Kgu and PAM chain segments. When assembled dual-cationic Kgu/PAM GPE to a flexible solid-state asymmetric supercapacitor, it delivers a high ionic conductivity (86.9 mS cm −1 ), an excellent energy rate density (86.1 Wh kg −1 ) and outstanding power density (476 W kg −1 ). In addition, dual-cationic Kgu/PAM GPE exhibits an excellent strain threshold of 910 % and remarkable mechanical strength of 35 KPa, good flexibility and flame retardant, highlighting the potential for its practical application in various fields. Collectively, these findings herald a novel paradigm in the development of secure and efficacious flexible wearables.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Jufen Yan,Lu Dai,Pei Wang,Yongsheng He,Qi Wang,Yiliang Chen,Haowei Zhang,Abdallah S. Ali,Rasha H. Ahmed,Ivana Radojcic Redovnikovic,Kui Zhang,Hongliang Wang,Xinya Han
The development of multifunctional materials capable of serving both as high-efficiency adsorbents and high-performance supercapacitors is a critical challenge for environmental and energy applications. In this study, a novel zeolitic imidazole framework-8/mycelial pellet (ZIF-8/MP) composite was successfully synthesized using a simple in-situ growth and staged adsorption process. The MP with its three-dimensional porous structure, served as a scaffold, facilitating the uniform distribution of ZIF-8 across the porous carbon matrix. The resulting ZIF-8 in the ZIF-8/MP composite demonstrated a remarkable adsorption capacity for Congo red (CR), with a maximum capacity of 1428.57 mg/g. The adsorption mechanism was attributed to electrostatic interactions, zinc coordination, hydrogen bonding, and π–π conjugation, as confirmed by FTIR, XPS, and DFT analyses. After adsorption, the carbonized ZIF-8/MP composite demonstrated outstanding supercapacitor performance, achieving a specific capacitance of 113.4 F/g at 1 A/g, and maintaining 93 % capacitance retention after 5000 charge/discharge cycles. Additionally, the ZIF-8/MP composite effectively reduced the toxicity of CR, as demonstrated by phytotoxicity assays, underscoring its potential for environmental remediation. This innovative approach provides an eco-friendly, easily separable, efficient, and practical multifunctional material for transforming hazardous waste into valuable resources for environmental detoxification and energy storage applications.
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JOURNAL OF POWER SOURCES
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2024
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IF 8.1
Ziang Min,Qing Tian,Zhuanzhuan Shi,Xiangyu Ding,Chunxian Guo,Chang Ming Li,Xiaoshuai Wu
Microbial Fuel Cells (MFCs) have garnered significant research attention as promising candidates for efficient and eco-friendly energy storage solutions. However, the persistent obstacle of limited electron transfer efficiency continues to hinder their widespread adoption. This study innovatively tackles the challenge of low electron transfer efficiency in MFCs by copolymerizing a conjugated polymer (PDA) with a photocatalytic material (TiO 2 ) onto Shewanella putrefaciens CN32 to create a hybrid microorganism. These hybrids, particularly when utilized as catalysts within MFCs under light illumination, significantly boosted electron transfer rates. Remarkably, the hybrid microorganism demonstrated an impressive current density of 1.07 mA/cm 2 in darkness, which soared to 5.657 mA/cm 2 under illumination. This microorganism exemplifies the synergistic interplay between the PDA and TiO 2 , where the PDA serves as an electron accumulator, while TiO 2 converts photons into valuable energy, ultimately enhancing the overall electrochemical performance of the MFCs. This work not only underscores the potential of integrating conjugated polymers and photocatalytic technology within bioelectrochemical systems but also expands the avenues for the development of more efficient and sustainable MFCs.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Yuyang Yao,Yueyue Lu,Jingwen Xu,Liang Guo,Heda Ding,Yitao Chen,Yuna Shi,Junbin Liao,Edison Huixiang Ang,Zhenlu Shen,Jiangnan Shen
To mitigate biofouling and maintain the properties of the anion exchange membranes (AEMs) in electrodialysis (ED) processes, conferring specialized functional coatings onto surfaces has proven effective in reducing susceptibility to biofouling. In this research, AEM substrates were synthesized using the conventional chemical assembly method, involving the reaction of 1-butylimidazole (BIm) with commercially available bromomethylated poly(2,6-dimethyl-1,4-phenylene oxide) (BPPO). Subsequently, a synergistic anti-biofouling system comprising graphene oxide (GO) and Ag nanoparticles (NPs) co-mingled casting-solution was formulated into a 2-μm coating through spraying onto the AEM surface. Exceptional static antibacterial activity of this system towards prevalent Gram-negative ( E. coli ) and Gram-positive ( S. aureus ) bacteria due to contact killing mechanisms. The dynamic anti-biofilm capability of post-electrodialysis AEM was evaluated using confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM), revealing consistent efficacy. Notably, the enhancement of anti-biofouling properties was achieved without compromising separation efficiency, as the coating solution shares the same composition as the substrate membrane. Crucially, the co-sprayed coating technique on the AEM surface overcomes the conventional “trade-off phenomenon” between performance and stability. This approach to fabricating anti-biofouling AEMs is believed to provide valuable insights for further optimization and application, thereby facilitating their deployment in water treatment and related fields.
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MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 12
·1-10
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IF 5.3
Duan Xiaoge,Shi Xinrui,He Zhaoyuan,Chen Hongcai,Shi Zhuanzhuan,Zhao Zhi,Chen Hailan,Yu Meiling,Guo Chunxian
Escherichia coli ( E. coli ) O157:H7 is an important food-borne pathogen that can cause hemorrhagic diarrhea and enteritis in humans and animals. Realizing the rapid quantitation of E. coli O157:H7 is of great significance for the guarantee of food safety and disease control. In this study, an electrochemical immunosensing technique based on a functionalized composite of Cu-metal organic framework (Cu-MOF) and poly (3,4-ethylenedioxythiophene)-poly (styrenesulfonate) (PEDOT:PSS) is developed, achieving rapid and sensitive quantitation of E. coli O157:H7 in food and clinical feces samples. The organic functionalization of Cu-MOF significantly improves the interface conductivity to facilitate electron transfer and provides the sulfonic groups (–SO 3 H) to conjugate bio-recognizing elements for target determination. The immunosensor delivers a linear detection range of 3 × 10 2 ~ 3 × 10 8 cfu/mL, a low limit of detection (LOD) of 7.4 cfu/mL, and a short analysis time of 40 min. In addition, it does not show any cross-reactivity with other common pathogens and exhibits high repeatability with relative standard deviations (RSDs) all lower than 2.09%, providing a promising approach for warranting food safety and control of E. coli O157:H7 disease. Graphical Abstract
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BioTech
·
2025
·Vol. 14
·期 1
·18
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IF 3.1
Yao Lu,Qiang Jiang,Yamin Dong,Runzhen Ji,Yiwen Xiao,Du Zhu,Boliang Gao
The GH43 family of glycosidases represents an important class of industrial enzymes that are widely utilized across the food, pharmaceutical, and various other sectors. In this study, we identified a GH43 family glycoside hydrolytic enzyme,Xyaf313, derived from the plant endophytic fungusChaetomium globosumDX-THS3, which is capable of transforming several common ginsenosides. The enzyme function analysis reveals that Xyaf313 exhibits dual functionality, displaying both α-L-arabinofuranosidase and β-D-xylosidase activity. When acting as an α-L-arabinofuranosidase, Xyaf313 achieves optimal enzyme activity of 23.96 U/mg at a temperature of 50 °C and a pH of 7. In contrast, its β-D-xylosidase activity results in a slight reduction in enzyme activity to 23.24 U/mg, with similar optimal temperature and pH conditions to those observed for the α-L-arabinofuranosidase activity. Furthermore, Xyaf313 demonstrates considerable resistance to most metal ions and common chemical reagents. Notably, while the maximum enzyme activity of Xyaf313 occurs at 50 °C, it maintains high activity at room temperature (30 °C), with relative enzyme activity exceeding 90%. Measurements of ginsenoside transformation show that Xyaf313 can convert common ginsenosides Rc, Rb1, Rb2, and Rb3into Rd, underscoring its potential for pharmaceutical applications. Overall, our findings contribute to the identification of a new class of bifunctional GH43 glycoside hydrolases, highlight the significance of plant endophytic fungi as a promising resource for the screening of carbohydrate-decomposing enzymes, and present new candidate enzymes for the biotransformation of ginsenosides.
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APPLIED SURFACE SCIENCE
·
2024
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IF 6.3
Qin Huang,Chunling Xie,Xiufeng Xiao
Two primary obstacles impede the longevity of implants: bacterial infection and fixation loosening. This research introduces an innovative near-infrared (NIR) light-activated drug delivery system tailored to enhance the antimicrobial efficacy and bone integration of titanium-based implants. Titanium dioxide nanotube arrays (TNTs) were modified with epoxy for covalent bonding of therapeutic agents, and copper sulfide nanoparticles (CuS NPs) were added for regulated drug release. Alendronate sodium (ALN), an osteoporosis medication, was successfully bonded to the nanotubes. In vitro experiments showed that the release rate of ALN from TNTs-ALN reached 94 % within 36 h. In contrast, minimal release was observed in TNTs-ECH-ALN-CuS, which effectively addresses the prevalent issue of abrupt drug discharge typical in conventional delivery systems. In the context of NIR light exposure, the TNTs-ECH-ALN-CuS exhibited a notable ALN release efficacy of 48 %, demonstrating effective control over drug delivery. Additionally, the generation of ROS, coupled with temperature elevation under NIR exposure, endowed the modified TNTs with exceptional antibacterial efficacy, exceeding 99 % inhibition against E.coli and S.aureus . We observed a pronounced enhancement in the drug delivery mechanism, characterized by a reduction in the initial burst release and a sustained, controlled release, coupled with robust antibacterial action and notable biological performance.
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