Cell Death & Disease
·
2020
·Vol. 11
·期 12
·1-14
·
IF 6.304
Huang Xiaozhong,Shi Yujuan,Chen Hongjin,Le Rongrong,Gong Xiaohua,Xu Ke,Zhu Qihan,Shen Feixia,Chen Zimiao,Gu Xuemei,Chen Xiaojun,Chen Xiong
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the effect of ISL in protecting against the injury in STZ-induced type 1 DN and in high glucose-induced NRK-52E cells. In this study, it was revealed that the administration of ISL not only ameliorated renal fibrosis and apoptosis, but also induced the deterioration of renal function in diabetic mice. Mediated by MAPKs and Nrf-2 signaling pathways, respectively, upstream inflammatory response and oxidative stress were neutralized by ISL in vitro and in vivo. Moreover, as further revealed by the results of molecular docking, sirtuin 1 (SIRT1) binds to ISL directly, and the involvement of SIRT1 in ISL-mediated renoprotective effects was confirmed by studies using in vitro models of SIRT1 overexpression and knockdown. In summary, by reducing inflammation and oxidative stress, ISL has a significant pharmacological effect on the deterioration of DN. The benefits of ISL are associated with the direct binding to SIRT1, the inhibition of MAPK activation, and the induction of Nrf-2 signaling, suggesting the potential of ISL for DN treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2020
·Vol. 8
·期 40
·14066-14074
·
IF 7.059
Yuxiang Wang,Xinan Shi,Gang Wang,Junye Tong,Daocheng Pan
Recently, the binary BiI3 semiconductor has emerged as a novel and potential absorbing material for thin film solar cells. In this work, high-quality BiI3 thin films are obtained by a two-step method via iodization of BiSI precursor thin films at low temperatures. The BiSI precursor solution is made via a Bi(OH)3/I2/butylamine/CS2 method. After the iodization process, the BiSI thin film transforms into a large-grain BiI3 absorber layer. The grain size of the BiI3 thin film is more than 1 μm, which leads to a low density of defects. It is worth-noticing that all of the procedures are conducted in open air. The temperature and duration of the iodization process are systematically investigated. By selecting V2O5 and ZnO as a hole extraction layer and an electron transport layer, an all-inorganic BiI3 thin film solar cell with a structure of ITO/V2O5/BiI3/ZnO/Ag is fabricated, yielding a power conversion efficiency of 1.33%, along with an open-circuit voltage of 601 mV, a short-circuit current density of 5.57 mA cm−2 and a fill factor of 39.87%. The un-encapsulated device shows excellent stability, and the performance decreases by only 8.1% after 100 days of storage in dry air.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Yanfei Wu,Zhuanhong Jia,Chunmiao Bo,Xiaojun Dai
In this study, we successfully prepared two magnetic graphene oxide composites, specifically (mGO @ ILs(1)-βCD and mGO @ ILs(2)-βCD), with different ionic liquid functional group substitution contents on the β-cyclodextrin (β-CD). Structural characterization of the composite material was performed using Fourier transform infrared spectroscopy , X-ray diffraction, field emission scanning electron microscopy , specific surface area and pore volume measurements. Comparison of the adsorption performance of the two materials for anionic dyes (lemon yellow (LY), sunset yellow (SY), and ponceau 4R (P4R)) in simulated wastewater. Effect of initial pH value, contact time were studied and discussed in terms of affinity and adsorption efficiency. The adsorption of the anionic azo dye by two adsorbent followed Langmuir adsorption isotherm models and pseudo-second-order kinetics. Noticeably, the maximum adsorption capacity based on the Langmuir model showed that mGO @ ILs(2)-βCD was better than mGO @ ILs(1)-βCD. Additionally, the adsorbent maintains excellent adsorption capacity after five cycles of adsorption-desorption and has remarkable selective separability. The results showed that the high-density substitution content of the ionic liquid functional groups on β-cyclodextrin in mGO @ ILs(2)-βCD is helpful to improve the adsorption capacity and efficiency.
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHEMISTRY COMMUNICATIONS
·
2020
·
IF 4.333
Jihuai Wu,Shaoyun Wu,Weihai Sun
A polyoxometalate (H 3 PW 12 O 40 , PW 12 )-doped polypyrrole (PW 12 -PPy) hybrid film was successfully prepared by electropolymerization. The PW 12 -PPy composite film was used as an efficient Pt-free counter electrode in a dye-sensitized solar cell (DSSC). The surface appearance, chemical composition and internal phase structure of the samples were investigated by scanning electron microscopy, infrared spectroscopy and X-ray diffraction. Electrochemical impedance spectroscopy and cyclic voltammetry measurements recorded using the prepared electrodes indicate that the PW 12 -PPy electrode has a higher reduction peak current density and a smaller series resistance than the Pt electrode, suggesting that the electrocatalytic activity of the PW 12 -PPy electrode for I 3 − reduction is better than that of the Pt electrode. Under simulated solar irradiation (AM 1.5) with an intensity of 100 mW⋅cm −2 , the DSSC based on the PW 12 -PPy counter electrode produces an average power conversion efficiency (PCE) of 6.19%; this efficiency value is on a par with that of similar devices using Pt as the cathode (6.25%).
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2020
·Vol. 13
·期 20
·4647
·
IF 3.057
Xu Chen,Yang Zhang,Yashuai Pang,Qiwei Jiang
To satisfy the high requirement of catalytic activity for efficient dye-sensitized solar cells (DSSCs), a novel nanoporous NiS film with inverse opal structure and outstanding electrocatalytic properties was prepared by a facile template-assisted electrodeposition method. The inverse opal structure makes the film have a larger specific surface area and more catalytic sites, thereby result to a higher electrocatalytic activity. Compared with the flat NiS/FTO electrode, this kind of nanoporous NiS film with inverse opal structure has higher catalytic activity and can be used as a cheap and efficient Pt-free electrode to replace the traditional Pt/FTO electrode. It is of great significance to reduce the cost and promote the wide application of DSSCs. This study opens up a new experimental exploration for further improving the catalytic activity of NiS electrode and the according photovoltaic efficiency of DSSCs. The template-assisted electrodeposition method proposed in this work provides a facile method for morphology control and an easy to be realized way to optimize the catalytic performance of the metal sulfides counter electrode.Keywords:electrocatalytic activity;nanoporous NiS film;template method;dye-sensitized solar cells;counter electrode
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2020
·
IF 3.784
Dongmei Pu,Pengju Chen,Peng Xiao,Zhuan Li,Pingyi Deng,Liang Pang,Jinwei Li,Yang Li
A dense and uniform c -AlPO 4 and SiC whisker co-modified mullite coating was successfully prepared on SiC-coated C/SiC composites with a thickness of about 70 μm by hydrothermal electrophoretic deposition . The thermal cycling performance of the coating samples was evaluated by thermally cycling between 1773 K and room temperature in a corundum tube furnace. Results show that the addition of SiC whisker (SiC w -mullite coating) significantly improved the thermal cycling resistance of single mullite outer layer on account of the toughening mechanism of SiC whiskers, such as whisker bridging and crack deflection. Then, the addition of c -AlPO 4 ( c -AlPO 4 -SiC w -mullite coating, termed ASM coating) further improved the thermal cycling resistance on account of the healing and bonding performances of c -AlPO 4 at high temperature. After 40 thermal cycles, the weight loss of ASM coating on SiC-coated C/SiC composites was 4.5% compared to 5.24% for the SiC w -mullite coating. The retention rate of compressive strength of ASM coating on SiC-coated C/SiC matrix was 80.66% compared to 73.65% for the SiC w -mullite coating.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Lingchen Meng,Shan Jiang,Meiyu Song,Fei Yan,Wei Zhang,Bin Xu,Wenjing Tian
Fluorescent thermometers with near-infrared (NIR) emission play an important role in visualizing the intracellular temperature with high resolution and investigating the cellular functions and biochemical activities. Herein, we designed and synthesized a donor−Π–acceptor luminogen, 2-([1,1′-biphenyl]-4-yl)-3-(4-((E)-4-(diphenylamino)styryl) phenyl) fumaronitrile (TBB) by Suzuki coupling reaction. TBB exhibited twisted intramolecular charge transfer-based NIR emission, aggregation-induced emission, and temperature-sensitive emission features. A ratiometric fluorescent thermometer was constructed by encapsulating thermosensitive NIR fluorophore TBB and Rhodamine 110 dye into an amphiphilic polymer matrix F127 to form TBB&R110@F127 nanoparticles (TRF NPs). TRF NPs showed a good temperature sensitivity of 2.37%·°C–1, wide temperature response ranges from 25 to 65 °C, and excellent temperature-sensitive emission reversibility. Intracellular thermometry experiments indicated that TRF NPs could monitor the cellular temperature change from 25 to 53 °C for Hep-G2 cells under the photothermal therapy agent heating process, indicating the considerable potential applications of TRF NPs in the biological thermometry field.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NANO
·
2020
·
IF 1.566
Bo Tang,Li Ji,Yuanzhe Dai,Haiqun Chen,Zhenyu Zhang,Zhengwei Wang,Sen Li
MOF-based composite material is adopted to modify photoanode, and the obtained large BET area is found meaningful to the dye loading amount, which brings about a high short circuit current and incident photon to current conversion efficiency. Meanwhile, three-dimensional graphene networks (3DGNs) are employed to provide a fast transport channel for photo-induced electrons. The morphology is analyzed by SEM, TEM, XRD and Raman spectrum, and the photovoltaic performances are recorded to reveal the specific functions of MOF and 3DGNs. The synergy between MOF, 3DGNs and TiO 2 is achieved by adjusting their mass fraction. Moreover, the average size of MOF exerts a significant influence on the resulting properties resulting from the scattering ability to incident light. After corresponding optimizing, the short circuit current, open circuit voltaic, fill factor and energy conversion efficiency reach 20.5 mAcm − 2 , 680 mV, 0.619% and 8.63%.
✓ 已验证
产品关联
DOI
高影响因子
Particuology
·
2020
·
IF 2.787
Zhou Lan,Yangcheng Lu
In this work, we used the inert substances silicone oil and n -hexane to modulate the solvent environment, and in so doing tailor the preparation of magnesium ethoxide (Mg(OEt) 2 ) particles. We found the following: (1) nonpolar n -hexane mainly modulates the polarity of the solvent to control the precipitation rate and size of the Mg(OEt) 2 seeds, thereby triggering accelerated nucleation to form small primary particles; and (2) silicone oil (relatively high polarity and viscosity) facilitates the growth and agglomeration stage, to improve inter-particle dispersion and obtain relatively uniform Mg(OEt) 2 particles. We summarized these findings in a common mechanism for preparing Mg(OEt) 2 particles with uniform morphology, small size, and high bulk density as per the synergistic effect of n -hexane and silicone oil. The ratios of silicone oil and n -hexane are flexible, and afford various regular and well-dispersed Mg(OEt) 2 particles that are 5–30 μm in size and 0.2–0.7 g/cm 3 in bulk density. The nanoparticles thus have the potential to serve in diverse applications such as catalysis.
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2020
·Vol. 25
·期 5
·1157
·
IF 3.267
Sha Cong,Wenjiang Dong,Jianping Zhao,Rongsuo Hu,Yuzhou Long,Xiaoxing Chi
The lipid oxidation process of Robusta green coffee beans was characterized during accelerated storage for 20 days at 40 °C, 50 °C, and 60 °C. The conventional oxidation indexes and fatty acid compositions were evaluated, and the shelf life of the green coffee beans was predicted using the Arrhenius model. The acid value, iodine value, peroxide value, total oxidation value, thiobarbituric acid reactive substances, and free fatty acid content increased throughout storage, while the moisture content,p-anisidine value, and unsaturated fatty acid content decreased, which suggests that lipid oxidation occurred during accelerated storage. The predicted shelf life of green coffee bean samples were 57.39 days, 44.44 days, and 23.12 days when stored at 40 °C, 50 °C, and 60 °C, respectively. This study provided scientific evidence of the impact of lipid oxidation on the loss of quality during the accelerated storage of green coffee beans.Keywords:green coffee beans;lipid oxidation;accelerated storage;shelf life prediction
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Yanfeng He,Zhenyu Zhang,Weiyang Wang,Lipei Fu
Metal organic frameworks (MOFs) and reduced graphene oxide (RGO) are used to modify photoanodes of dyes sensitized solar cells (DSSCs) to improve their photovoltaic performances . The MOFs are found that bring about a significant enhancement of the BET area of photoanodes, which endows a high dye adsorption capacity. Moreover, the added MOFs introduces an improved incident photon to electron efficiency because of the remarkably enhanced scattering power for the incident light. On the other hand, in the presence of RGO provides a fast transport channel for photo-induced electrons, which depresses the dark current of the resulting devices. After optimizing the mass fraction of MOFs and RGO, the synergy has been achieved. Moreover, by using a graphene-based counter electrode, the photovoltaic performances of the resulting full-carbon DSSCs are detected. The short-circuit current, open-circuit voltage, fill factor (FF) and energy conversion efficiency ( η ) reach 18.6 mAcm −2 , 682 mV, 0.608 and 7.67%, indicating the potential application prospection of the as-prepared photoanodes.
✓ 已验证
产品关联
DOI
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2020
·
IF 4.551
Yuhang Wu,Yuanbo Xie,Fangyuan Zhong,Junkuo Gao,Juming Yao
It is of great significance to capture radioiodine from nuclear-related activities. Herein, We fabricated two kinds of hybrid aerogels composed with bimetal Hofmann-type metal-organic frameworks (Co–Fe) II (pz)[Ni II (CN) 4 ] and cellulose aerogels by in-situ growth and doping method (named CoFe@CA-IS and CoFe@CA-D, respectively). The hybrid aerogels possessed excellent iodine adsorption performance. The addition of (Co–Fe) II (pz)[Ni II (CN) 4 ] increased the porosity of the hybrid aerogels. The porosities of CoFe@CA-IS and CoFe@CA-D were reached 86.7% and 87.8%, respectively, which are higher than pure cellulose aerogels. Furthermore, the doping method provide a significant improve of adsorption performance. The equilibrium adsorption capacity of CoFe@CA-D reached 457.99 mg g −1 and the equilibrium adsorption capacity of CoFe@CA-IS was 194.34 mg g −1 . In addition, the hybrid aerogels showed excellent recycle ability, the equilibrium adsorption capacity of CoFe@CA-IS and CoFe@CA-D remained 81% and 91% after 5 cycles. The results suggested that this metal-organic framework@cellulose hybrid aerogel showed great potential in iodine treatment and could be applied in a wide field.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）